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SI2853545T1 - Protitelesa, specifična za IgE - Google Patents

Protitelesa, specifična za IgE

Info

Publication number
SI2853545T1
SI2853545T1 SI200931501A SI200931501A SI2853545T1 SI 2853545 T1 SI2853545 T1 SI 2853545T1 SI 200931501 A SI200931501 A SI 200931501A SI 200931501 A SI200931501 A SI 200931501A SI 2853545 T1 SI2853545 T1 SI 2853545T1
Authority
SI
Slovenia
Prior art keywords
ige
antibody specific
antibody
specific
Prior art date
Application number
SI200931501A
Other languages
English (en)
Inventor
John R. Desjarlais
Seung Y. Chu
Holly M. Horton
Original Assignee
Xencor Inc.,
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Xencor Inc., filed Critical Xencor Inc.,
Publication of SI2853545T1 publication Critical patent/SI2853545T1/sl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • C07K16/4283—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an allotypic or isotypic determinant on Ig
    • C07K16/4291—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an allotypic or isotypic determinant on Ig against IgE
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C07K16/461—Igs containing Ig-regions, -domains or -residues form different species
    • C07K16/464—Igs containing CDR-residues from one specie grafted between FR-residues from another
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SI200931501A 2008-09-17 2009-09-17 Protitelesa, specifična za IgE SI2853545T1 (sl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US9781908P 2008-09-17 2008-09-17
EP14188102.9A EP2853545B8 (en) 2008-09-17 2009-09-17 Antibody specific for IgE
EP09792678.6A EP2331578B1 (en) 2008-09-17 2009-09-17 Novel compositions and methods for treating ige-mediated disorders
EP13185738.5A EP2703415B1 (en) 2008-09-17 2009-09-17 Compositions and methods for treating IgE-mediated disorders

Publications (1)

Publication Number Publication Date
SI2853545T1 true SI2853545T1 (sl) 2016-10-28

Family

ID=41510648

Family Applications (2)

Application Number Title Priority Date Filing Date
SI200931927T SI3190128T1 (sl) 2008-09-17 2009-09-17 Sestavki in postopki za zdravljenje motenj, posredovanih z IgE
SI200931501A SI2853545T1 (sl) 2008-09-17 2009-09-17 Protitelesa, specifična za IgE

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SI200931927T SI3190128T1 (sl) 2008-09-17 2009-09-17 Sestavki in postopki za zdravljenje motenj, posredovanih z IgE

Country Status (20)

Country Link
US (9) US8435517B2 (sl)
EP (7) EP3190128B1 (sl)
JP (2) JP5785493B2 (sl)
KR (1) KR101783272B1 (sl)
CN (2) CN102292353B (sl)
AU (1) AU2009293143C1 (sl)
BR (1) BRPI0918670B8 (sl)
CA (1) CA2736511C (sl)
CY (2) CY1118002T1 (sl)
DK (3) DK2796469T3 (sl)
ES (6) ES2727677T3 (sl)
HR (1) HRP20182135T1 (sl)
HU (2) HUE042901T2 (sl)
LT (2) LT3190128T (sl)
PL (2) PL2853545T3 (sl)
PT (2) PT2853545T (sl)
SI (2) SI3190128T1 (sl)
SM (1) SMT201600288B (sl)
TR (1) TR201821216T4 (sl)
WO (1) WO2010033736A1 (sl)

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