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PT3129470T - Tratamento de cancro usando o recetor de antigénios quiméricos anti-cd19 - Google Patents

Tratamento de cancro usando o recetor de antigénios quiméricos anti-cd19

Info

Publication number
PT3129470T
PT3129470T PT157190430T PT15719043T PT3129470T PT 3129470 T PT3129470 T PT 3129470T PT 157190430 T PT157190430 T PT 157190430T PT 15719043 T PT15719043 T PT 15719043T PT 3129470 T PT3129470 T PT 3129470T
Authority
PT
Portugal
Prior art keywords
cancer
treatment
antigen receptor
chimeric antigen
chimeric
Prior art date
Application number
PT157190430T
Other languages
English (en)
Original Assignee
Univ Pennsylvania
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Pennsylvania, Novartis Ag filed Critical Univ Pennsylvania
Publication of PT3129470T publication Critical patent/PT3129470T/pt

Links

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
    • A61K2239/26—
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
    • A61K2239/31—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterized by the route of administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
    • A61K2239/38—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the dose, timing or administration schedule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
    • A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the cancer treated
    • A61K2239/48—Blood cells, e.g. leukemia or lymphoma
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
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    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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    • C07—ORGANIC CHEMISTRY
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    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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  • Public Health (AREA)
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  • Pharmacology & Pharmacy (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
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  • Biochemistry (AREA)
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  • Biophysics (AREA)
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  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Virology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PT157190430T 2014-04-07 2015-04-07 Tratamento de cancro usando o recetor de antigénios quiméricos anti-cd19 PT3129470T (pt)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201461976396P 2014-04-07 2014-04-07
US201462007309P 2014-06-03 2014-06-03
US201462036493P 2014-08-12 2014-08-12
US201462076238P 2014-11-06 2014-11-06
US201462087888P 2014-12-05 2014-12-05
US201462097278P 2014-12-29 2014-12-29

Publications (1)

Publication Number Publication Date
PT3129470T true PT3129470T (pt) 2021-07-13

Family

ID=53008859

Family Applications (2)

Application Number Title Priority Date Filing Date
PT211602032T PT3888674T (pt) 2014-04-07 2015-04-07 Tratamento de cancro usando o recetor de antigénios quiméricos anti-cd19
PT157190430T PT3129470T (pt) 2014-04-07 2015-04-07 Tratamento de cancro usando o recetor de antigénios quiméricos anti-cd19

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PT211602032T PT3888674T (pt) 2014-04-07 2015-04-07 Tratamento de cancro usando o recetor de antigénios quiméricos anti-cd19

Country Status (24)

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US (2) US10357514B2 (pt)
EP (3) EP3888674B1 (pt)
JP (3) JP6765966B2 (pt)
KR (3) KR20240042250A (pt)
CN (2) CN107075482B (pt)
AU (2) AU2015244039B2 (pt)
CA (1) CA2940671A1 (pt)
DK (2) DK3129470T3 (pt)
ES (1) ES2876263T3 (pt)
FI (1) FI3888674T3 (pt)
HR (2) HRP20240874T1 (pt)
HU (2) HUE054588T2 (pt)
IL (4) IL307423A (pt)
LT (2) LT3129470T (pt)
MX (2) MX2016013239A (pt)
MY (1) MY191608A (pt)
PL (2) PL3888674T3 (pt)
PT (2) PT3888674T (pt)
RU (1) RU2718542C2 (pt)
SG (2) SG11201606909RA (pt)
SI (2) SI3129470T1 (pt)
TW (1) TWI753848B (pt)
WO (1) WO2015157252A1 (pt)
ZA (1) ZA201605657B (pt)

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US10155038B2 (en) 2007-02-02 2018-12-18 Yale University Cells prepared by transient transfection and methods of use thereof
WO2010099205A1 (en) * 2009-02-24 2010-09-02 The Trustees Of The University Of Pennsylvania Methods for treating progressive multifocal leukoencephalopathy (pml)
US10940169B2 (en) 2015-11-30 2021-03-09 Joseph E. Kovarik Method for reducing the likelihood of developing cancer in an individual human being
US11951140B2 (en) 2011-02-04 2024-04-09 Seed Health, Inc. Modulation of an individual's gut microbiome to address osteoporosis and bone disease
US11951139B2 (en) 2015-11-30 2024-04-09 Seed Health, Inc. Method and system for reducing the likelihood of osteoporosis
US11998479B2 (en) 2011-02-04 2024-06-04 Seed Health, Inc. Method and system for addressing adverse effects on the oral microbiome and restoring gingival health caused by sodium lauryl sulphate exposure
US11844720B2 (en) 2011-02-04 2023-12-19 Seed Health, Inc. Method and system to reduce the likelihood of dental caries and halitosis
ES2814962T3 (es) 2013-02-20 2021-03-29 Novartis Ag Fijación eficaz como objetivo de la leucemia humana primaria utilizando células T modificadas con receptor de antígeno quimérico anti-CD123
MY190711A (en) 2013-02-20 2022-05-12 Novartis Ag Treatment of cancer using humanized anti-egfrviii chimeric antigen receptor
ES2769574T3 (es) * 2013-03-15 2020-06-26 Michael C Milone Reconocimiento de células citotóxicas con receptores quiméricos para inmunoterapia adoptiva
UY35468A (es) 2013-03-16 2014-10-31 Novartis Ag Tratamiento de cáncer utilizando un receptor quimérico de antígeno anti-cd19
CN106459989B (zh) 2013-12-19 2023-02-17 诺华股份有限公司 人间皮素嵌合抗原受体及其用途
US11833177B2 (en) 2013-12-20 2023-12-05 Seed Health, Inc. Probiotic to enhance an individual's skin microbiome
EP3087101B1 (en) 2013-12-20 2024-06-05 Novartis AG Regulatable chimeric antigen receptor
US11998574B2 (en) 2013-12-20 2024-06-04 Seed Health, Inc. Method and system for modulating an individual's skin microbiome
US11213552B2 (en) 2015-11-30 2022-01-04 Joseph E. Kovarik Method for treating an individual suffering from a chronic infectious disease and cancer
US11026982B2 (en) 2015-11-30 2021-06-08 Joseph E. Kovarik Method for reducing the likelihood of developing bladder or colorectal cancer in an individual human being
US11980643B2 (en) 2013-12-20 2024-05-14 Seed Health, Inc. Method and system to modify an individual's gut-brain axis to provide neurocognitive protection
US11529379B2 (en) 2013-12-20 2022-12-20 Seed Health, Inc. Method and system for reducing the likelihood of developing colorectal cancer in an individual human being
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