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PL3103784T3 - Wytwarzanie emulsji typu olej w wodzie zawierającej skwalen - Google Patents

Wytwarzanie emulsji typu olej w wodzie zawierającej skwalen

Info

Publication number
PL3103784T3
PL3103784T3 PL16176832T PL16176832T PL3103784T3 PL 3103784 T3 PL3103784 T3 PL 3103784T3 PL 16176832 T PL16176832 T PL 16176832T PL 16176832 T PL16176832 T PL 16176832T PL 3103784 T3 PL3103784 T3 PL 3103784T3
Authority
PL
Poland
Prior art keywords
squalene
manufacture
oil
water emulsion
emulsion
Prior art date
Application number
PL16176832T
Other languages
English (en)
Inventor
Maninder Hora
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44358794&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL3103784(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of PL3103784T3 publication Critical patent/PL3103784T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C11/00—Aliphatic unsaturated hydrocarbons
    • C07C11/21—Alkatrienes; Alkatetraenes; Other alkapolyenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/01—Hydrocarbons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/145—Orthomyxoviridae, e.g. influenza virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D3/00—Distillation or related exchange processes in which liquids are contacted with gaseous media, e.g. stripping
    • B01D3/10—Vacuum distillation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D3/00—Distillation or related exchange processes in which liquids are contacted with gaseous media, e.g. stripping
    • B01D3/14—Fractional distillation or use of a fractionation or rectification column
    • B01D3/143—Fractional distillation or use of a fractionation or rectification column by two or more of a fractionation, separation or rectification step
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/10—Wash bottles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C7/00—Purification; Separation; Use of additives
    • C07C7/04—Purification; Separation; Use of additives by distillation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Water Supply & Treatment (AREA)
  • Analytical Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Pulmonology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Clinical Laboratory Science (AREA)
  • Biophysics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
PL16176832T 2010-05-12 2011-05-12 Wytwarzanie emulsji typu olej w wodzie zawierającej skwalen PL3103784T3 (pl)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US39544810P 2010-05-12 2010-05-12
EP13164769.5A EP2620423B2 (en) 2010-05-12 2011-05-12 Improved methods for preparing squalene
EP11738802.5A EP2569267B2 (en) 2010-05-12 2011-05-12 Improved methods for preparing squalene
EP16176832.0A EP3103784B1 (en) 2010-05-12 2011-05-12 Manufacture of an oil-in-water emulsion comprising squalene
PCT/IB2011/001397 WO2011141819A1 (en) 2010-05-12 2011-05-12 Improved methods for preparing squalene

Publications (1)

Publication Number Publication Date
PL3103784T3 true PL3103784T3 (pl) 2019-07-31

Family

ID=44358794

Family Applications (4)

Application Number Title Priority Date Filing Date
PL13164769T PL2620423T5 (pl) 2010-05-12 2011-05-12 Ulepszone sposoby otrzymywania skwalenu
PL11738802T PL2569267T5 (pl) 2010-05-12 2011-05-12 Ulepszone sposoby otrzymywania skwalenu
PL16176832T PL3103784T3 (pl) 2010-05-12 2011-05-12 Wytwarzanie emulsji typu olej w wodzie zawierającej skwalen
PL19151232T PL3489211T3 (pl) 2010-05-12 2011-05-12 Ulepszone sposoby otrzymywania skwalenu

Family Applications Before (2)

Application Number Title Priority Date Filing Date
PL13164769T PL2620423T5 (pl) 2010-05-12 2011-05-12 Ulepszone sposoby otrzymywania skwalenu
PL11738802T PL2569267T5 (pl) 2010-05-12 2011-05-12 Ulepszone sposoby otrzymywania skwalenu

Family Applications After (1)

Application Number Title Priority Date Filing Date
PL19151232T PL3489211T3 (pl) 2010-05-12 2011-05-12 Ulepszone sposoby otrzymywania skwalenu

Country Status (20)

Country Link
US (5) US9199897B2 (pl)
EP (4) EP3103784B1 (pl)
JP (2) JP5946188B2 (pl)
KR (1) KR101875894B1 (pl)
CN (2) CN105125488A (pl)
AU (1) AU2011251706B2 (pl)
BR (1) BR112012028711B1 (pl)
CA (1) CA2798924C (pl)
EA (1) EA027142B1 (pl)
ES (4) ES2817446T3 (pl)
IL (1) IL222855A (pl)
MX (1) MX352758B (pl)
NZ (1) NZ603918A (pl)
PL (4) PL2620423T5 (pl)
PT (3) PT2620423T (pl)
SG (2) SG10201503689TA (pl)
SI (1) SI2569267T1 (pl)
TR (1) TR201905021T4 (pl)
WO (1) WO2011141819A1 (pl)
ZA (1) ZA201208381B (pl)

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EP2906239A1 (en) 2012-10-12 2015-08-19 GlaxoSmithKline Biologicals SA Non-cross-linked acellular pertussis antigens for use in combination vaccines
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JP7555929B2 (ja) 2018-12-24 2024-09-25 遠大賽威信生命科学（南京）有限公司 Ｂ型肝炎を治療するための薬物製剤、その製造方法及び用途
WO2023056089A1 (en) 2021-10-03 2023-04-06 Eisai R&D Management Co., Ltd. Immunological adjuvant formulations comprising tlr4 agonist e6020
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Also Published As

Publication number Publication date
SI2569267T1 (sl) 2014-03-31
EA027142B1 (ru) 2017-06-30
MX352758B (es) 2017-12-07
ES2597158T3 (es) 2017-01-16
PT3103784T (pt) 2019-05-20
PL3489211T3 (pl) 2020-12-14
SG10201503689TA (en) 2015-06-29
EP2620423B1 (en) 2016-07-20
US20170072053A1 (en) 2017-03-16
EA201291225A1 (ru) 2013-06-28
PL2569267T5 (pl) 2017-10-31
BR112012028711A2 (pt) 2017-03-21
EP3103784B1 (en) 2019-02-06
EP2620423A1 (en) 2013-07-31
US9867877B2 (en) 2018-01-16
PL2569267T3 (pl) 2014-05-30
EP2569267B1 (en) 2013-12-25
EP3489211B1 (en) 2020-07-15
US10517947B2 (en) 2019-12-31
JP5946188B2 (ja) 2016-07-05
PL2620423T5 (pl) 2019-12-31
JP2015157858A (ja) 2015-09-03
BR112012028711B1 (pt) 2020-12-01
KR101875894B1 (ko) 2018-08-02
ES2717266T3 (es) 2019-06-20
NZ603918A (en) 2015-04-24
KR20130103668A (ko) 2013-09-24
US11077186B2 (en) 2021-08-03
US9545440B2 (en) 2017-01-17
CA2798924C (en) 2014-05-06
WO2011141819A1 (en) 2011-11-17
ES2817446T3 (es) 2021-04-07
CN102892734A (zh) 2013-01-23
CN105125488A (zh) 2015-12-09
TR201905021T4 (tr) 2019-05-21
PT2620423T (pt) 2016-09-23
ES2453316T5 (es) 2017-07-18
ES2453316T3 (es) 2014-04-07
CA2798924A1 (en) 2011-11-17
PT3489211T (pt) 2020-09-22
EP2620423B2 (en) 2019-07-31
PL2620423T3 (pl) 2017-09-29
MX2012013027A (es) 2012-12-17
US9199897B2 (en) 2015-12-01
AU2011251706A1 (en) 2012-12-20
EP3489211A1 (en) 2019-05-29
US20180169225A1 (en) 2018-06-21
US20130209510A1 (en) 2013-08-15
SG185419A1 (en) 2012-12-28
ZA201208381B (en) 2014-04-30
AU2011251706B2 (en) 2015-10-22
US20160051670A1 (en) 2016-02-25
US20200061187A1 (en) 2020-02-27
JP2013530941A (ja) 2013-08-01
ES2597158T5 (es) 2020-03-26
EP3103784A1 (en) 2016-12-14
CN102892734B (zh) 2015-07-22
IL222855A (en) 2015-11-30
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EP2569267A1 (en) 2013-03-20

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