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KR910019982A - 시아노퀴놀린 화합물 - Google Patents

시아노퀴놀린 화합물 Download PDF

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Publication number
KR910019982A
KR910019982A KR1019910007170A KR910007170A KR910019982A KR 910019982 A KR910019982 A KR 910019982A KR 1019910007170 A KR1019910007170 A KR 1019910007170A KR 910007170 A KR910007170 A KR 910007170A KR 910019982 A KR910019982 A KR 910019982A
Authority
KR
South Korea
Prior art keywords
alkyl
substituted
hydrogen
group
general formula
Prior art date
Application number
KR1019910007170A
Other languages
English (en)
Korean (ko)
Inventor
하겐 헬무트
피스터 위르겐
브릴 군터
닐츠 게르하르트
뷔르쩌 브루노
베스트팔렌 카알-오토
Original Assignee
바르츠, 비텐베르크
바스프 악티엔게젤샤프트
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 바르츠, 비텐베르크, 바스프 악티엔게젤샤프트 filed Critical 바르츠, 비텐베르크
Publication of KR910019982A publication Critical patent/KR910019982A/ko

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/12Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/32Ingredients for reducing the noxious effect of the active substances to organisms other than pests, e.g. toxicity reducing compositions, self-destructing compositions
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Agronomy & Crop Science (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
KR1019910007170A 1990-05-03 1991-05-03 시아노퀴놀린 화합물 KR910019982A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DEP4014171.3 1990-05-03
DE4014171A DE4014171A1 (de) 1990-05-03 1990-05-03 Cyanochinolinverbindungen

Publications (1)

Publication Number Publication Date
KR910019982A true KR910019982A (ko) 1991-12-19

Family

ID=6405624

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019910007170A KR910019982A (ko) 1990-05-03 1991-05-03 시아노퀴놀린 화합물

Country Status (8)

Country Link
US (1) US5565408A (de)
EP (1) EP0459140B1 (de)
JP (1) JPH04225960A (de)
KR (1) KR910019982A (de)
CA (1) CA2041684A1 (de)
DE (2) DE4014171A1 (de)
ES (1) ES2091258T3 (de)
HU (1) HU209438B (de)

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* Cited by examiner, † Cited by third party
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DE4201720A1 (de) * 1992-01-23 1993-07-29 Basf Ag Thiochromenonderivate als antidots und sie enthaltende herbizide mittel
DE4227896A1 (de) * 1992-08-22 1994-02-24 Basf Ag Cyclohexenonoximether, ihre Herstellung und ihre Verwendung
PL330814A1 (en) 1996-06-20 1999-06-07 Regents Board Of Compounds for and methods of delivering pharmaceutical preparations and their application
US7157408B2 (en) * 2003-12-11 2007-01-02 Valent Biosciences Corporation Quinoline fungicides
AU2009274037B2 (en) * 2008-07-22 2015-07-09 Trustees Of Dartmouth College Monocyclic cyanoenones and methods of use thereof
SI2651902T1 (en) 2010-12-17 2018-02-28 Reata Pharmaceuticals, Inc. Tricyclic pyrazolyl and pyrimidinylenones as antioxidant inflammatory modulators
US9682966B2 (en) * 2012-08-16 2017-06-20 The Scripps Research Institute Kappa opioid ligands
EP3662751B1 (de) * 2015-05-26 2021-10-13 Kaohsiung Medical University Pyrazolo[4,3-c]chinolin-derivate zur hemmung von b-glucuronidase
PE20180462A1 (es) 2015-07-06 2018-03-06 Gilead Sciences Inc Moduladores cot y metodos de uso de los mismos
TW202235416A (zh) 2019-06-14 2022-09-16 美商基利科學股份有限公司 Cot 調節劑及其使用方法
JP2022552019A (ja) 2019-10-18 2022-12-14 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 病的血管障害の治療のための作用物質としての3-フェニルスルホニル-キノリン誘導体
EP4126231A1 (de) 2020-03-30 2023-02-08 Gilead Sciences, Inc. Feste formen von (s)-6-((1-(bicyclo[1.1.1]pentan-1-yl)-1h-1,2,3-triazol-4-yl)2-methyl-1-oxo-1,2-dihydroisochinolin-5-yl)amino)8-chlor-(neopentylamino)chinolin-3-carbonsäure
KR20220160645A (ko) 2020-04-02 2022-12-06 길리애드 사이언시즈, 인코포레이티드 Cot 저해제 화합물의 제조 방법

Family Cites Families (33)

* Cited by examiner, † Cited by third party
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US2507146A (en) * 1946-03-12 1950-05-09 Eastman Kodak Co Method of making a 3-halo-2-methylquinoline
US2991285A (en) * 1958-09-09 1961-07-04 Rohm & Haas Process of cyanation and nitriles produced thereby
DE1170955B (de) * 1961-06-10 1964-05-27 Bayer Ag Verfahren zur Herstellung von 2-Methylmercapto-3-cyano-4-chlorchinolin
GB1207771A (en) * 1968-03-18 1970-10-07 Warner Lambert Pharmaceutical Anti-virally active quinoline derivatives
LU65139A1 (de) * 1972-04-07 1973-10-22
HU167910B (de) * 1972-11-22 1976-01-28
SE406911B (sv) * 1973-08-28 1979-03-05 Chinoin Gyogyszer Es Vegyeszet Sett att framstella nya kinolinderivat
DE2363459A1 (de) * 1973-12-20 1975-06-26 Basf Ag Neue fluoreszierende chinolinverbindungen
US4362876A (en) * 1978-08-11 1982-12-07 The Sherwin-Williams Company Preparation of dihydroxyquinoline and certain derivatives
US4488898A (en) * 1978-08-31 1984-12-18 Ciba-Geigy Corporation Oxime derivatives for protecting plant crops
US4490167A (en) * 1979-08-06 1984-12-25 Ciba-Geigy Corporation Oxime derivatives of diphenyl ethers and their use in herbicidal compositions
US4456468A (en) * 1980-01-14 1984-06-26 Ciba-Geigy Corporation Aminoglyoxylonitrile oximiro carbamates for the protection of crops against injury by herbicides
US4497651A (en) * 1982-02-17 1985-02-05 Basf Aktiengesellschaft Dichloroquinoline derivatives for use as herbicides
MA19709A1 (fr) * 1982-02-17 1983-10-01 Ciba Geigy Ag Application de derives de quinoleine a la protection des plantes cultivees .
EP0089313B1 (de) * 1982-03-15 1985-05-02 Ciba-Geigy Ag Neue Oximäther, Verfahren zu ihrer Herstellung, Mittel die die neuen Oximäther enthalten und ihre Verwendung
DE3210979A1 (de) * 1982-03-25 1983-09-29 Basf Ag, 6700 Ludwigshafen 3-chlor-8-cyano-chinoline, verfahren zu ihrer herstellung und ihre verwendung zur bekaempfung unerwuenschten pflanzenwuchses
SE8206378L (sv) * 1982-11-10 1984-05-11 Sverker Hogberg Nya kelatbildande kinolinforeningar
US4496569A (en) * 1983-03-25 1985-01-29 The Dow Chemical Company Antiallergic (1H-tetrazol-5-yl)tetrazolo[1,5-a]quinolines and derivatives thereof
US4496725A (en) * 1983-05-23 1985-01-29 The Dow Chemical Company Substituted 1,2,3-triazino[4',5':4,5]-thieno[2,3-B]quinolin-4(3H)-ones
US4540786A (en) * 1983-08-22 1985-09-10 The Dow Chemical Company Preparation of 2-chloro-3-cyano-quinolines
ATE47001T1 (de) * 1984-03-15 1989-10-15 Ciba Geigy Ag Verwendung von chinolinderivaten zum schuetzen von kulturpflanzen.
EP0159290A1 (de) * 1984-03-28 1985-10-23 Ciba-Geigy Ag Verwendung von Chinolinderivaten zum Schützen von Kulturpflanzen
DE3620856A1 (de) * 1986-06-21 1987-12-23 Basf Ag 3-cyanchinolinderivate
EP0258184A3 (de) * 1986-08-13 1988-11-30 Ciba-Geigy Ag Chinolinderivate als Herbizid- antagonisten für Kulturpflanzen
GB8702613D0 (en) * 1987-02-05 1987-03-11 Ici Plc Compositions
US4920128A (en) * 1987-07-08 1990-04-24 Sterling Drug Inc. Pyrazolo[3,4-b]quinolines and their use as antiviral agents
US4933447A (en) * 1987-09-24 1990-06-12 Ss Pharmaceutical Co., Ltd. Quinoline derivatives
GB8727737D0 (en) * 1987-11-26 1987-12-31 Ici Plc Antitumour agents
IE892088L (en) * 1988-07-12 1990-01-12 William Henry Deryk Morris Quinoline derivatives, their production and use
DE3829851A1 (de) * 1988-09-02 1990-03-08 Basf Ag Tetraazaporphyrine sowie strahlungsempfindliche beschichtungsfilme
DE3837926A1 (de) * 1988-11-09 1990-05-17 Basf Ag Herbizide mittel, die 2-(4-heteroaryloxy)- oder 2-(4-aryloxy)-phenoxyessig- oder -propionsaeurederivate und/oder cyclohexenonderivate als herbizide wirkstoffe und naphthalinderivate als antidots enthalten, sowie ihre verwendung zur bekaempfung unerwuenschten pflanzenwuchses
DE3907938A1 (de) * 1989-03-11 1990-09-13 Basf Ag 2,3-substituierte 1,8-naphthyridine, verfahren zu ihrer herstellung und ihre verwendung als antidots
US4929128A (en) * 1989-06-23 1990-05-29 Affleck Robert J Masonry drill assembly

Also Published As

Publication number Publication date
DE4014171A1 (de) 1991-11-07
HUT57539A (en) 1991-12-30
DE59108164D1 (de) 1996-10-17
CA2041684A1 (en) 1991-11-04
JPH04225960A (ja) 1992-08-14
EP0459140A2 (de) 1991-12-04
ES2091258T3 (es) 1996-11-01
US5565408A (en) 1996-10-15
EP0459140B1 (de) 1996-09-11
HU911479D0 (en) 1991-11-28
HU209438B (en) 1994-06-28
EP0459140A3 (en) 1992-05-20

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