KR102613672B1 - A composition that does not irritate the skin and has excellent skin moisture containing the extract of emilia coccinea - Google Patents
A composition that does not irritate the skin and has excellent skin moisture containing the extract of emilia coccinea Download PDFInfo
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- KR102613672B1 KR102613672B1 KR1020210131834A KR20210131834A KR102613672B1 KR 102613672 B1 KR102613672 B1 KR 102613672B1 KR 1020210131834 A KR1020210131834 A KR 1020210131834A KR 20210131834 A KR20210131834 A KR 20210131834A KR 102613672 B1 KR102613672 B1 KR 102613672B1
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- skin
- composition
- extract
- skin moisturizing
- cacalia
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9706—Algae
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/007—Preparations for dry skin
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2200/00—Function of food ingredients
- A23V2200/30—Foods, ingredients or supplements having a functional effect on health
- A23V2200/318—Foods, ingredients or supplements having a functional effect on health having an effect on skin health and hair or coat
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2250/00—Food ingredients
- A23V2250/20—Natural extracts
- A23V2250/202—Algae extracts
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/85—Products or compounds obtained by fermentation, e.g. yoghurt, beer, wine
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- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
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- Biotechnology (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Microbiology (AREA)
- Dermatology (AREA)
- Nutrition Science (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- Chemical & Material Sciences (AREA)
- Cosmetics (AREA)
Abstract
본 발명은 카칼리아 추출물을 유효 성분으로 포함하는 피부 보습용 조성물로, 피부 자극이 없고, 피부 보습 효과가 우수한 조성물에 관한 것으로, 화장료 조성물로 제공되어, 피부에 도포 시 피부 자극이 없어, 피부 트러블의 발생을 유발하지 않고, 천연물질 유래 성분을 포함하여 환경성 피부 질환을 가지는 경우에도 사용이 가능하며, 우수한 피부 보습 효과를 나타낼 수 있다.
또한, 식품 조성물로 제공되어, 섭취에 의한 피부 보습 효과를 나타낼 수 있다.The present invention relates to a skin moisturizing composition containing Cacalia extract as an active ingredient, which does not cause skin irritation and has an excellent skin moisturizing effect. It is provided as a cosmetic composition and does not cause skin trouble when applied to the skin. It does not cause the occurrence of , can be used even in cases of environmental skin diseases as it contains ingredients derived from natural substances, and can have an excellent skin moisturizing effect.
Additionally, it can be provided as a food composition and have a skin moisturizing effect upon ingestion.
Description
본 발명은 카칼리아 추출물을 유효 성분으로 포함하는 피부 자극이 없고, 피부 보습 효과가 우수한 조성물에 관한 것이다. The present invention relates to a composition containing Cacalia extract as an active ingredient, which does not cause skin irritation and has excellent skin moisturizing effect.
피부는 신체 중 가장 큰 기관으로 항상 외부와 접하고 있으면서, 여러 가지 자극이나 건조한 환경으로부터 생체를 보호하는 보호막의 역할을 하고 있으며, 다른 기관에 비하여 새로운 세포의 생성과 소멸이 활발히 일어나는 기관이다. 또한, 물리적인 찰과상으로부터 보호하고, 몸 안에 가지고 있는 물의 손실을 막아주며, 태양으로부터 나오는 해로운 자외선으로부터 보호해주고, 몸의 체온을 조절해주는데 매우 중요한 역할을 담당하고 있다. 아기 피부는 하얗고 부드러우며 여드름 같은 염증이 없는 것이 일반적이다. 그러나 아기 피부는 결코 성인들이 이상적이라 생각하는 것처럼 좋은 것은 아니다. 오히려 극히 미성숙한 상태로 인해 외부와의 경계를 이루는 각질층이 성인에 비해 얇고 각질층의 수분 함유량 및 각질층이 보유한 중요한 기능 중 하나인 표피의 보호 장벽 기능이 약한 것이다. 이러한 이유로 아기피부는 외부영향에 민감하며, 바이러스에 쉽게 노출될 수 있다. 이렇듯 아기 피부는 건조한 피부가 되기 쉽고 이 건조한 피부는 면역기능이 약화되어 아토피 피부염뿐만 아니라 여러 피부 질환으로 발전할 수도 있으며, 마찬가지로 약하고 민감한 피부일수록 항염 및 피부 자극완화 기능의 강화 가 절실하다고 하겠다.The skin is the largest organ in the body and is always in contact with the outside world. It acts as a protective layer that protects the living body from various stimuli or dry environments. Compared to other organs, the skin is an organ where the creation and extinction of new cells occurs more actively. It also plays a very important role in protecting against physical abrasions, preventing the loss of water in the body, protecting against harmful ultraviolet rays from the sun, and regulating body temperature. Baby's skin is generally white, soft, and free of inflammation such as acne. However, baby skin is never as good as adults think is ideal. Rather, due to its extremely immature state, the stratum corneum that forms the border with the outside is thinner than that of an adult, and the moisture content of the stratum corneum and the protective barrier function of the epidermis, which is one of the important functions of the stratum corneum, are weak. For this reason, baby skin is sensitive to external influences and can be easily exposed to viruses. As such, baby skin is prone to dry skin, and this dry skin can weaken immune function, which can lead to not only atopic dermatitis but also various skin diseases. Similarly, the weaker and more sensitive the skin is, the more urgent it is to strengthen anti-inflammatory and skin irritation-relieving functions.
일반적으로 피부에 적용되는 제품 가운데는 자극이나 염증, 알레르기를 유발할 수 있는 물질을 함유하고 있는 경우가 많아서 개인 관리 제품 (Personal care products)을 사용하는 사람 중 10% 이상이 피부에 대한 부작용을 호소하고 있으며, 1990년대 미국에서 소비자를 대상으로 조사한 결과 50% 이상이 자신을 민감성 피부라고 생각 하고 있는 것으로 나타났다. 더구나, 최근의 화장품은 피부에 실질적인 효과(real effect)를 줄 수 있는 기능성 화장품(cosmeceutical)에 치중하는 경향을 보이므로 화장품 등의 개인 관리 제품의 사용으로 인한 피부 부작용은 점점 증가할 것으로 보인다.In general, many products applied to the skin contain substances that can cause irritation, inflammation, or allergies, so more than 10% of people who use personal care products complain of side effects on the skin. A survey of consumers in the United States in the 1990s found that more than 50% considered themselves to have sensitive skin. Moreover, as recent cosmetics tend to focus on functional cosmetics that can have real effects on the skin, skin side effects due to the use of personal care products such as cosmetics are expected to increase.
이처럼 민감 피부라고 느끼고 있는 비율이 증가하고 있는 요인은 오존층 파괴에 따른 자외선 조사량 증가, 생활 공간의 건조화, 개인의 알레르기 체질, 스트레스, 화학 유해 물질의 증가 등이 거론되고 있으며, 한편으로 최근 소비자의 지향이 자연 친화적, 저자극으로 이행되고 있는 것도 민감 피부에 대한 의식을 향상시키는 요인이 되고 있는 것으로 추측되고 있다. 따라서 화장품의 자극을 완화시켜 주는 물질에 대한 관심이 높아지고 있다.The factors that are causing the increase in the proportion of people feeling that they have sensitive skin include increased ultraviolet irradiation due to ozone layer destruction, drying of living spaces, individual allergic constitution, stress, and increase in chemical harmful substances. On the other hand, recent consumer trends It is presumed that this transition to a nature-friendly and hypoallergenic diet is also a factor in improving awareness of sensitive skin. Therefore, interest in substances that relieve irritation from cosmetics is increasing.
최근 국민들의 생활수준이 향상되면서 피부와 관련된 기능성 화장품에 대한 관심과 수요가 급증하고 있지만, 합성소재 기능성 화장품과 관련된 부작용이 지속적으로 제기되면서 효과적이면서도 독성이 없는 천연물을 이용한 화장품 개발연구가 활발히 진행되고 있다. 천연물을 이용한 화장품 개발연구는 안전함과 동시에 피부자극이 없고, 피부보습력을 향상시키는 효과적인 화장품 소재 발굴의 일환으로 기능성 천연물에 대한 지속적인 개발이 필요하다.Recently, as people's living standards have improved, interest in and demand for skin-related functional cosmetics has been rapidly increasing. However, as side effects related to functional cosmetics made of synthetic materials continue to be raised, research on the development of cosmetics using effective and non-toxic natural products is being actively conducted. there is. Cosmetic development research using natural products requires continuous development of functional natural products as part of the discovery of effective cosmetic materials that are safe, do not irritate the skin, and improve skin moisturization.
이에, 천연 추출물을 포함함으로써 부작용의 문제가 없고 피부 자극이 없어 사용에 불편함이 없으며, 피부 보습 효과가 우수한 화장료 조성물의 개발이 필요하다.Accordingly, there is a need to develop a cosmetic composition that contains natural extracts, has no problems with side effects, does not cause skin irritation, does not cause discomfort in use, and has excellent skin moisturizing effects.
본 발명의 목적은 카칼리아 추출물을 유효 성분으로 포함하는 피부 보습용 조성물로, 피부 자극이 없고, 피부 보습 효과가 우수한 조성물을 제공하는 것이다. The purpose of the present invention is to provide a skin moisturizing composition containing Cacalia extract as an active ingredient, which does not cause skin irritation and has excellent skin moisturizing effect.
본 발명의 다른 목적은 화장료 조성물로 제공되어, 피부에 도포 시 피부 자극이 없어, 피부 트러블의 발생을 유발하지 않고, 카칼리아 추출물과 같은 천연물질 유래 성분을 포함하여 환경성 피부 질환을 가지는 경우에도 사용이 가능하며, 우수한 피부 보습 효과를 나타낼 수 있는 조성물을 제공하는 것이다. Another object of the present invention is to provide a cosmetic composition that does not cause skin irritation when applied to the skin, does not cause skin troubles, and contains ingredients derived from natural substances such as Cacalia extract, so that it can be used even in cases of environmental skin diseases. The aim is to provide a composition that is possible and can exhibit excellent skin moisturizing effects.
본 발명의 다른 목적은 식품 조성물로 제공되어, 섭취에 의한 피부 보습 효과를 나타낼 수 있는 조성물을 제공하는 것이다. Another object of the present invention is to provide a composition that can be provided as a food composition and exhibit a skin moisturizing effect upon ingestion.
상기 목적을 달성하기 위하여, 본 발명의 일 실시예에 따른 피부 보습용 조성물은 카칼리아 추출물을 유효 성분으로 포함한다.In order to achieve the above object, a composition for skin moisturizing according to an embodiment of the present invention includes Cacalia extract as an active ingredient.
상기 조성물은 피부 자극이 없고, 피부 보습 효과가 우수하다. The composition does not cause skin irritation and has excellent skin moisturizing effect.
상기 추출물은 물, 탄소수 1 내지 6의 저급 알코올 및 이들의 혼합물로 이루어진 군으로부터 선택되는 어느 하나를 추출 용매로 하여 추출된 것이다. The extract is extracted using any one selected from the group consisting of water, lower alcohols having 1 to 6 carbon atoms, and mixtures thereof as an extraction solvent.
상기 조성물은 발효 해조류 추출물을 추가로 포함할 수 있다.The composition may further include fermented seaweed extract.
본 발명의 다른 일 실시예에 따른 피부 보습용 화장료 조성물은 상기 피부 보습용 조성물을 포함한다. A cosmetic composition for moisturizing skin according to another embodiment of the present invention includes the composition for moisturizing skin.
상기 화장료 조성물은 스킨, 세럼, 로션, 에멀전, 크림, 에센스, 화장수, 파운데이션, 팩, 비누, 계면활성제-함유 클렌징, 스프레이 및 파우더로 구성된 군으로부터 선택된 제형일 수 있다.The cosmetic composition may be a formulation selected from the group consisting of skin, serum, lotion, emulsion, cream, essence, lotion, foundation, pack, soap, surfactant-containing cleansing, spray, and powder.
본 발명의 다른 일 실시예에 따른 피부 보습용 기능성 식품 조성물은 상기 피부 보습용 조성물을 포함한다. A functional food composition for skin moisturizing according to another embodiment of the present invention includes the skin moisturizing composition.
이하, 본 발명을 더욱 상세하게 설명한다.Hereinafter, the present invention will be described in more detail.
인체에 있어서 피부는 외부환경으로부터 생체를 보호하는 보호막의 기능을 하는 기관으로서, 인체 내의 생체성 분 즉, 물이나 전해질 등의 손실을 방지하는 동시에 외부로부터 유해물질이 인체 내로 침입하지 못하도록 하는 역할을 한다. In the human body, the skin is an organ that functions as a protective film that protects the living body from the external environment. It prevents the loss of biological components in the human body, such as water and electrolytes, and also prevents harmful substances from entering the human body from the outside. do.
이러한 피부는 크게 표피층, 진피층 및 피하지방층으로 구분된다. 표피층은 각질세포와 멜라닌 세포로 구성되는데, 피부 최외곽의 각질세포층은 외부환경과 직접 접촉하기 때문에 물리적, 화학적 혹은 물질의 투과에 대한 강한 저항성이 요구되며, 인체로부터 외부로 수분이 손실되는 것을 막아줌과 동시에 자체로도 적당한 수분을 보유함으로써 유연성을 유지하여야 한다.This skin is largely divided into the epidermis layer, dermis layer, and subcutaneous fat layer. The epidermal layer is composed of keratinocytes and melanocytes. The outermost keratinocyte layer of the skin is in direct contact with the external environment, so it requires strong resistance to physical, chemical, or material penetration, and prevents moisture loss from the human body to the outside. It must maintain flexibility by retaining adequate moisture while simultaneously shrinking.
일반적으로 피부의 수분량은 진피층에서는 70% 정도이나 표피층으로 갈수록 감소하여 각질세포층에서는 약 10 내지 30%가 된다. 진피층에서 공급된 물은 주로 수동적 확산에 의해 각질층 상부로 이동하며 최종적으로는 외부로 배출된다. In general, the moisture content of the skin is about 70% in the dermis layer, but decreases toward the epidermis layer, reaching about 10 to 30% in the keratinocyte layer. Water supplied from the dermal layer mainly moves to the upper part of the stratum corneum by passive diffusion and is ultimately discharged to the outside.
이를 경피수분손실(Trans Epidermal Water Loss:TEWL)이라 하며, 이러한 경피수분손실을 적절한 수준으로 유지시켜주는 것이 각질세포층의 지질막 성분인 피지성분과 표피지질이라고 알려져 있다. 그리고 각질 세포층에는 천연보습 인자(Natural Moisturizing Factor:NMF)라고 하는 친수성의 수분 보유능을 가진 물질이 존재하여 피부의 보습에 중요한 역할을 담당하는 것으로 알려져 있다. This is called Trans Epidermal Water Loss (TEWL), and it is known that the sebum component and epidermal lipid, which are lipid membrane components of the keratinocyte layer, maintain this transepidermal water loss at an appropriate level. In addition, it is known that the keratinocyte layer contains a hydrophilic substance with water-retaining ability called Natural Moisturizing Factor (NMF), which plays an important role in moisturizing the skin.
정상적인 각질세포층의 수분이 10 내지 30% 정도가 유지되면 피부는 매끄럽고 부드러우며, 신체 보호기능을 정상적으로 발휘하게 된다. 그러나 각질세포층의 수분함량이 10% 이하가 되면 피부는 거칠어지고 신체의 보호기능을 잃게 되어 노화현상이 일어난다. When the moisture content of the normal keratinocyte layer is maintained at about 10 to 30%, the skin is smooth and soft and functions to protect the body normally. However, when the moisture content of the keratinocyte layer falls below 10%, the skin becomes rough and loses its protective function, causing aging.
예를 들어, 건성피부의 경우에는 각질세포의 결집력이 약화되어 피부표면으로부터 비늘조각과 같이 각질세포가 허옇게 벗겨져 나오는 스케일링(Scaling) 현상이 나타나는 바, 이와 같이 피부가 건성화되는 것은 각질세포층의 수분함량이 정상피부에 비해 적기 때문이다. For example, in the case of dry skin, the cohesion of keratinocytes is weakened and a scaling phenomenon occurs in which keratinocytes peel off from the skin surface like scales. This drying of the skin is due to the moisture content of the keratinocyte layer. This is because it is less than normal skin.
이 밖에, 건강한 피부라 할지라도 혹독한 외부환경, 즉, 바람, 추운 날씨, 햇빛, 세안, 면도 등에 의해 수분 부족현상이 일어나 피부상태가 나빠지기도 한다. In addition, even if the skin is healthy, the skin condition may worsen due to lack of moisture due to harsh external environments, such as wind, cold weather, sunlight, washing the face, and shaving.
따라서 피부의 각질세포층의 수분함량을 적절히 유지하는 것은 매우 중요하다. 각질층의 수분이 10 % 이하일 경우, 피부는 건성화되고 피부트러블의 원인이 된다고 알려져 있다. 규칙적인 각질화(keratinization)로 생성된 각질층 안의 수분의 양은 항상 10 내지 20 %를 유지한다.Therefore, it is very important to maintain the appropriate moisture content of the skin's keratinocyte layer. It is known that when the moisture content of the stratum corneum is less than 10%, the skin becomes dry and causes skin problems. The amount of moisture in the stratum corneum created by regular keratinization is always maintained at 10 to 20%.
현재 피부내 수분 유지방법 은폐색제(occlusive agent)를 사용하고 있으며, 폐색제는 수분손실을 막는 장벽을 피부위에 형성함으로써, 수분보유를 촉진하는 소수성 물질이다. Currently, occlusive agents are used to retain moisture in the skin. Occlusive agents are hydrophobic substances that promote moisture retention by forming a barrier on the skin that prevents moisture loss.
가장 일반적으로 사용되는 폐색제에는, 바세린, 라놀린, 코코아버터, 미네랄 오일 및 실리콘이 포함된다. 또한 화장품을 만들기 위해서는 이외에도 소듐라우릴 설페이트 (Sodium Lauryl Sulfate), 디메틸 술폭사이드(Dimethyl Sulfoxide), 크로톤오일(Croton Oil), 수산화 나트륨등과 같이 일반적으로 20종에서 50여종의 다양한 원료들이 사용되며, 이들 원료들이 제품에 적용됨으로써 피부에 염증, 가려움증, 알러지 등의 자극을 일으킬 수 있다.The most commonly used occlusives include petrolatum, lanolin, cocoa butter, mineral oil, and silicone. In addition, to make cosmetics, 20 to 50 different raw materials are generally used, such as sodium lauryl sulfate, dimethyl sulfoxide, croton oil, sodium hydroxide, etc. When these raw materials are applied to products, they can cause skin irritation such as inflammation, itching, and allergies.
본 발명의 조성물은 피부에 도포 시, 피부 자극이 없고, 우수한 피부 보습 효과를 나타내는 것을 주요 특징으로 한다. The main characteristic of the composition of the present invention is that it does not cause skin irritation when applied to the skin and exhibits an excellent skin moisturizing effect.
본 발명의 일 실시예에 따른 피부 보습용 조성물은 카칼리아 추출물을 유효 성분으로 포함한다. A skin moisturizing composition according to an embodiment of the present invention includes Cacalia extract as an active ingredient.
상기 카칼리아(Emilia coccinea)는 쌍떡잎식물 초롱꽃목 국화과의 한해살이풀로 인도가 원산지이고 관상 식물로 재배한다. 잎은 어긋나고 긴 달걀 모양이며 가장자리에 둔한 톱니가 있고 잎자루가 없으며 분을 칠한 것처럼 보인다. 꽃은 6∼10월에 주황색이 도는 붉은 색으로 피고 가는 꽃줄기 끝에 두상화(頭狀花, 꽃대 끝에 꽃자루가 없는 작은 꽃이 많이 모여 피어 머리 모양을 이룬 꽃)가 달린다. 두상화는 관상화로 구성되며, 관상화의 화관은 5개로 갈라진다. 열매는 수과이다. 봄에 파종하며 성질이 강하다. 카칼리아란 과거의 속명(屬名)인 Cacalia에서 유래했으며, 불꽃씀바귀와 비슷하다.The Emilia coccinea is an annual herb of the dicotyledonous plant Campanula Asteraceae, is native to India, and is cultivated as an ornamental plant. The leaves are alternate, long egg-shaped, have dull sawtooth edges, have no petioles, and look like they are powdered. The flowers bloom in an orange-red color from June to October, and a capitate flower (a flower made up of many small flowers without peduncles blooming at the end of a flower stalk, forming a head) hangs at the end of a thin flower stem. The capitol flower is composed of tubular flowers, and the corolla of the tubular flower is divided into five parts. The fruit is an achene. It is sown in spring and has strong properties. Cacalia is derived from the old genus name Cacalia, and is similar to the fireweed.
상기 추출물은 물, 탄소수 1 내지 6의 저급 알코올 및 이들의 혼합물로 이루어진 군으로부터 선택되는 어느 하나를 추출 용매로 하여 추출될 수 있다. The extract may be extracted using any one selected from the group consisting of water, lower alcohols having 1 to 6 carbon atoms, and mixtures thereof as an extraction solvent.
구체적으로, 건조한 카칼리아를 분쇄하는 단계; 유기 용매를 사용하여 상기 분쇄물을 침출시키는 단계; 시료를 침출 후 건조시키는 단계; 건조된 시료를 유기 용매를 사용하여 재 침출시키는 단계; 시료를 침출 후 건조시키는 단계; 물을 이용하여 침출시키는 단계; 및 침출하는 단계를 포함하여, 카칼리아 추출물을 획득할 수 있다.Specifically, grinding dried Cacalia; leaching the pulverized material using an organic solvent; Leaching and drying the sample; Re-leaching the dried sample using an organic solvent; Leaching and drying the sample; Leaching using water; And including the step of leaching, a Cacalia extract can be obtained.
상기 유기 용매를 사용하여 추출한 카칼리아 추출물을 유기 용매를 사용하여 분획을 실시하는 단계를 더 포함할 수 있다.It may further include the step of fractionating the Cacalia extract extracted using the organic solvent using an organic solvent.
상기 추출물을 제조하는 방법은 초음파 추출법, 침출법 및 환류 추출법 등 당업계의 통상적인 추출 방법일 수 있다. 구체적으로 세척 및 건조로 이물질이 제거된 천연물을 물, 탄소수 1 내지 6의 알코올 또는 이들의 혼합 용매로 추출한 추출물일 수 있으며, 상기 용매들을 순차적으로 시료에 적용하여 추출한 추출물일 수도 있다.The method of preparing the extract may be a conventional extraction method in the art, such as ultrasonic extraction, leaching, and reflux extraction. Specifically, it may be an extract obtained by extracting a natural product from which foreign substances have been removed by washing and drying with water, an alcohol having 1 to 6 carbon atoms, or a mixed solvent thereof, or it may be an extract obtained by sequentially applying the solvents to the sample.
상기 환류 추출법은 탄소수 1 내지 6의 알코올 100mL기준으로, 천연물의 분쇄물 10 내지 30g, 환류 시간 1 내지 3시간 및 50 내지 100%의 탄소수 1 내지 6의 알코올에 의한다. 보다 구체적으로, 탄소수 1 내지 6의 알코올 100mL기준으로, 천연물의 분쇄물 10 내지 20g, 환류 시간 1 내지 2시간 및 70 내지 90%의 탄소수 1 내지 4의 알코올에 의한 것이다.The reflux extraction method is based on 100 mL of alcohol having 1 to 6 carbon atoms, 10 to 30 g of pulverized natural product, a reflux time of 1 to 3 hours, and 50 to 100% of alcohol having 1 to 6 carbon atoms. More specifically, based on 100 mL of alcohol with 1 to 6 carbon atoms, 10 to 20 g of pulverized natural product, reflux time of 1 to 2 hours, and 70 to 90% of alcohol with 1 to 4 carbon atoms.
상기 침출법은 15 내지 30℃, 24 내지 72시간 동안 및 50 내지 100%의 탄소수 1 내지 6의 알코올에 의한 것이다. 보다 구체적으로는 20 내지 25℃, 30 내지 54시간 동안 및 70 내지 80%의 탄소수 1 내지 6의 알코올에 의한 것이다.The leaching method is performed at 15 to 30° C. for 24 to 72 hours and 50 to 100% of alcohol with 1 to 6 carbon atoms. More specifically, at 20 to 25° C., for 30 to 54 hours, and 70 to 80% of alcohol having 1 to 6 carbon atoms.
상기 초음파 추출법은 30 내지 50℃, 0.5 내지 2.5시간 동안 및 50 내지 100%의 탄소수 1 내지 6의 알코올에 의한 것이다. 구체적으로는 40 내지 50℃, 1 내지 2.5시간 동안 및 70 내지 80%의 탄소수 1 내지 6의 알코올에 의한 것이다.The ultrasonic extraction method is performed at 30 to 50° C. for 0.5 to 2.5 hours and 50 to 100% alcohol with 1 to 6 carbon atoms. Specifically, at 40 to 50° C. for 1 to 2.5 hours and 70 to 80% of alcohol having 1 to 6 carbon atoms.
상기 추출 용매는 시료의 중량 기준으로 2 내지 50배를 사용할 수 있으며, 보다 구체적으로는 2 내지 20배이다. 추출을 위해 시료는 추출 용매에서 침출을 위해 1 내지 72 시간 동안 방치될 수 있으며, 보다 구체적으로 24 내지 48시간 동안 방치될 수 있다.The extraction solvent can be used in an amount of 2 to 50 times, more specifically, 2 to 20 times the weight of the sample. For extraction, the sample may be left for 1 to 72 hours, more specifically, 24 to 48 hours for leaching in the extraction solvent.
추출 후, 추출물은 새로운 분획 용매를 순차적으로 적용하여 분획할 수 있다. 분획시 사용하는 분획 용매는 상기 용매는 물, 헥산, 부탄올, 에틸아세트산, 에틸 아세테이트, 메틸렌클로라이드 및 이들의 혼합물로 이루어진 군으로부터 선택된 어느 하나 이상이며, 바람직하게는 에틸아세테이트 또는 메틸렌클로라이드이다.After extraction, the extract can be fractionated by sequentially applying a new fractionation solvent. The fractionating solvent used during fractionation is at least one selected from the group consisting of water, hexane, butanol, ethyl acetic acid, ethyl acetate, methylene chloride, and mixtures thereof, and is preferably ethyl acetate or methylene chloride.
추출물 또는 분획물을 얻은 후에는 농축 또는 동결건조 등의 방법을 추가적으로 사용할 수 있다.After obtaining the extract or fraction, additional methods such as concentration or freeze-drying can be used.
상기 조성물은 발효 해조류 추출물을 추가로 포함할 수 있다. 상기 피부 보습용 조성물은 카칼리아 추출물만 포함하는 경우에도 우수한 보습 효과 및 기호도 높은 보습용 조성물로 제공될 수 있으나, 발효 해조류 추출물과 혼합 사용에 의하여 상승된 보습 효과를 나타낼 수 있고, 기호도 높은 화장료 조성물 또는 식품 조성물로의 제공을 가능하게 한다. The composition may further include fermented seaweed extract. The skin moisturizing composition can be provided as a moisturizing composition with excellent moisturizing effect and high preference even when it contains only Cacalia extract. However, it can exhibit increased moisturizing effect by mixing with fermented seaweed extract and is a cosmetic composition with high preference. Or it makes it possible to provide it as a food composition.
또한, 상기 발효 해조류 추출물은 해조류 추출물을 그대로 이용 시, 해조류 특유의 이취로 인해 기호도가 떨어지는 문제가 있다. 이러한 문제를 방지하기 위해, 발효시킨 해조류로부터 유효 성분을 추출하고 이를 카칼리아 추출물과 혼합하여 사용 시, 보습 효과를 높일 뿐 아니라 기호도 높은 조성물로의 제공을 가능하게 한다. In addition, when the fermented seaweed extract is used as is, there is a problem in that the preference is lowered due to the unique off-flavor of the seaweed. To prevent this problem, extracting active ingredients from fermented seaweed and mixing them with Cacalia extract not only increases the moisturizing effect but also makes it possible to provide a composition with high preference.
상기 해조류 추출물은 구체적으로 꼬시래기 추출물, 파래 추출물, 모자반 추출물, 매생이 추출물, 톳 추출물, 미역 추출물, 김 추출물, 다시마 추출물, 감태 추출물, 우뭇가사리 추출물, 청각 추출물, 클로렐라 추출물, 함초 추출물, 세모가사리 추출물, 대황 추출물 및 이들의 혼합물로 이루어진 군에서 선택되며, 바람직하게는 꼬시래기 추출물, 세모가사리 추출물 및 이들의 혼합으로 이루어진 군으로부터 선택될 수 있으나, 상기 예시에 국한되지 않는다. The seaweed extract is specifically, seaweed extract, green seaweed extract, cap extract, seaweed extract, hijiki extract, seaweed extract, seaweed extract, kelp extract, Ecklonia cava extract, Agar extract, Agar extract, chlorella extract, Salicornia extract, Agar extract, and rhubarb. It may be selected from the group consisting of extracts and mixtures thereof, and preferably may be selected from the group consisting of Siberian lanceolate extract, Semogasari extract, and mixtures thereof, but is not limited to the above examples.
상기 꼬시래기(Gracilaria verrucosa)는 홍색 해조류의 일종으로 돌가사리목 꼬시래기과에 속하며 한국, 일본, 사할린섬, 타이완 등의 조간대의 돌과 조개껍데기 등에 붙어 자란다. 특히 강물이 바다 로 흘러 드는 얕은 바닷가의 자갈이나 말뚝 등에서 번식하며, 외해(外海)의 암초 위에서도 자란다. 몸통은 작은 쟁반 모양의 뿌리에서 모여나고 원기둥 모양이다. 촘촘하게 깃꼴로 갈라지고 가지는 한쪽으로 치우쳐 나기도 한다. 몸에서 뻗어 나온 가지는 지름 1mm 이하의 철사 모양을 한 연골질(軟骨質)로서 검은빛을 띤 자주색 또는 짙은 갈색으로, 직경 1-3㎜, 원기둥이 2-3m까지 성장하며, 약간 데쳐 무침으로 먹거나 한천 원료로 이용하기도 한다.Gracilaria verrucosa is a type of red seaweed that belongs to the family Gracilaria verrucosa and grows attached to stones and shells in the intertidal zone of Korea, Japan, Sakhalin Island, and Taiwan. In particular, it breeds on pebbles or piles in shallow beaches where river water flows into the sea, and also grows on reefs in the open sea. The body grows from small tray-shaped roots and has a cylindrical shape. It is densely divided into pinnate shapes, and the branches sometimes grow out to one side. The branches extending from the body are wire-shaped cartilaginous with a diameter of less than 1 mm, blackish purple or dark brown, 1-3 mm in diameter, and grow to a cylindrical length of 2-3 m. They are slightly boiled and eaten as a seasoning or agar. It is also used as a raw material.
상기 세모가사리(Gloiopeltis furcate)는 적갈색 한해살이 해조류로, 풀가사리 가운데 줄기가 가는 것을 의미한다. 세모가사리는 높이가 5 내지 15cm로 몸체가 원기둥 모양이고, 조금 불규칙적으로 가지가 갈라지며 체형은 자라는 곳에 따라 변화가 많다. 가지는 속이 비어 있으며 가지가 갈라지는 곳은 잘록하고 가지는 너비가 4mm에 달한다. 세모가사리는 겨울과 봄에 걸쳐 무성하게 자라고 초여름에 성숙하여 포자를 만든다. The Gloiopeltis furcate is a reddish-brown annual seaweed, which means that the stem is thin in the middle of the seaweed. Semogasari is 5 to 15 cm tall, has a cylindrical body, branches slightly irregularly, and its body shape varies greatly depending on where it grows. The branches are hollow, the branching points are narrow, and the width of the branches reaches 4 mm. Semogasari grows luxuriantly throughout winter and spring, matures in early summer and produces spores.
상기 발효 해조류 추출물은, 세척한 해조류를 발효 용기에 넣고 미생물을 접종하여 발효 숙성 공정을 진행한다. The fermented seaweed extract is subjected to a fermentation and aging process by placing washed seaweed in a fermentation vessel and inoculating microorganisms.
상기 미생물은 락토바실러스 살리바리우스(Lactobacillus salivarius), 락토바실러스 아시도필루스(Lactobacillus acidophilus), 락토바실러스 브레비스(Lactobacillus brevis), 락토바실러스 람노수스(Lactobacillus rhamnosus), 락토바실러스 플랜타룸(Lactobacillus plantarum), 락토바실러스 헬베티쿠스(Lactobacillus helveticus), 락토바실러스 퍼멘툼(Lactobacillus fermentum), 락토바실러스 파라카세이(Lactobacillus paracasei), 락토바실러스 카세이(Lactobacillus casei), 락토바실러스 델브루에키(Lactobacillus delbrueckii), 락토바실러스 레우테리(Lactobacillus reuteri), 락토바실러스 부츠네리(Lactobacillus buchneri), 락토바실러스 가세리(Lactobacillus gasseri), 락토바실러스 존스니(Lactobacillus johonsonii), 락토바실러스 케피르(Lactobacillus kefir) 등과 같은 유산 바실리, 락토코코스 락티스(Lactococcus lactis), 락토코코스 플랜타룸(Lactococcus plantarum), 락토코코스 라피노락티스(Lactococcus raffinolactis), 엔테로코코스파에칼리스(Enterococcus faecalis), 엔테로코코스 파에시늄(Enterococcus faecium), 스트렙토코코스 터모필리우스(Streptococcus thermophilus), 류코노스톡락티스(Leuconostoc lactis), 류코노스톡 메센테로이드(Leuconostoc mesenteroides) 등과 같은 유산 콕사이 및 비피도박테리움 애닐멀스(Bifidobacterium animals), 비피도 박테리움 비피듐(Bifidobacterium bifidum),비피도박테리움 브레브(Bifidobacterium breve), 비피도박테리움 인판티스(Bifidobacterium infantis), 비피도바테리움 롱굼(Bifidobacterium longum), 비피도박테리움 수도롱굼(Bifidobacterium pseudolongum), 비피도박테리움 터모필룸(Bifidobacterium themophilum), 비피도박테리움 아돌센티스(Bifidobacterium adolescentis) 등과 같은 비피도박테리아를 포함할 수 있으며, 더욱 바람직하게는 락토바실러스 카제이(Lactobacillus casei), 락토바실러스 람노수스(Lactobacillus rhamnosus), 비피도 박테리윰 비피듐(Bifidobacterium bifidum) 비피더스균, 비피도 박테리움 브레브(Bifidobacterium breve) 비피더스균, 및 락토바실러스 아시도 필루스(Lactobacillus acidophilus)로 이루어진 군에서 선택될 수 있으나, 상기 미생물의 범위에 한정되지 않고 제한 없이 사용 가능하다. The microorganisms include Lactobacillus salivarius, Lactobacillus acidophilus, Lactobacillus brevis, Lactobacillus rhamnosus, Lactobacillus plantarum, and lactobacillus. Lactobacillus helveticus, Lactobacillus fermentum, Lactobacillus paracasei, Lactobacillus casei, Lactobacillus delbrueckii, Lactobacillus reuteri ( Lactobacillus, Lactococcus, such as Lactobacillus reuteri, Lactobacillus buchneri, Lactobacillus gasseri, Lactobacillus johonsonii, Lactobacillus kefir, etc. lactis), Lactococcus plantarum, Lactococcus raffinolactis, Enterococcus faecalis, Enterococcus faecium, Streptococcus thermophilus, Leuconostoc lactis, Leuconostoc mesenteroides, etc. and Bifidobacterium animals, Bifidobacterium bifidum, Bifidobacterium breve, Bifidobacterium infantis, Bifidobacterium longum, Bifidobacterium pseudolongum, Bifidobacterium thermophilum It may include bifidobacteria such as (Bifidobacterium themophilum), Bifidobacterium adolescentis, etc., and more preferably Lactobacillus casei, Lactobacillus rhamnosus, and Bifidobacteria. Bifidobacterium bifidum may be selected from the group consisting of Bifidobacterium, Bifidobacterium breve, and Lactobacillus acidophilus, but may be selected from the group consisting of the above microorganisms. It is not limited and can be used without restrictions.
상기 미생물을 접종한 후, 1 내지 2일 동안 30 내지 35℃에서 발효 숙성 공정을 진행한다. 발효 숙성 공정이 완료되면, 상기 설명한 추출물 제조 공정에 의해 발효 해조류 추출물로 제조한다.After inoculating the microorganism, a fermentation and maturation process is performed at 30 to 35° C. for 1 to 2 days. Once the fermentation and maturation process is completed, the fermented seaweed extract is produced by the extract production process described above.
상기 조성물은 카칼리아 추출물 100 중량부에 대하여, 발효 꼬시래기 추출물 20 내지 40 중량부 및 발효 세모가사리 추출물 20 내지 40 중량부로 포함할 수 있다. 상기 범위 내에서 혼합하여 사용하는 경우, 피부 자극이 발생하지 않으며, 보습 효과가 상대적으로 개선될 뿐 아니라, 피부 발림성이 개선될 수 있다. The composition may include 20 to 40 parts by weight of fermented Siberian snail extract and 20 to 40 parts by weight of fermented Siberian cypress extract based on 100 parts by weight of Cacalia extract. When mixed and used within the above range, skin irritation does not occur, moisturizing effect is relatively improved, and skin applicability can be improved.
본 발명의 다른 일 실시예에 따른 피부 보습용 화장료 조성물은 상기 본 발명의 조성물을 포함한다. A cosmetic composition for moisturizing skin according to another embodiment of the present invention includes the composition of the present invention.
본 발명의 화장료 조성물은 본 발명의 조성물에 추가적으로 피부학적으로 허용된 담체를 혼합하여 제조될 수 있다. The cosmetic composition of the present invention can be prepared by additionally mixing the composition of the present invention with a dermatologically acceptable carrier.
상기 피부학적으로 허용된 담체는 정제수, 오일, 왁스, 지방산, 지방산 알코올, 지방산 에스테르, 계면활성제, 흡습제, 증점제, 항산화제, 점도 안정화제, 킬레이팅제, 완충제, 방부제, 저급 알코올 등이 포함될 수 있지만, 이에 한정되는 것은 아니며, 그 종류와 농도는 다양하고, 당업자가 본 발명의 범위 내에서 변경할 수 있는 부분을 포함한다. The dermatologically acceptable carrier may include purified water, oil, wax, fatty acid, fatty alcohol, fatty acid ester, surfactant, moisture absorbent, thickener, antioxidant, viscosity stabilizer, chelating agent, buffer, preservative, lower alcohol, etc. However, it is not limited to this, and its types and concentrations are diverse, and includes parts that can be changed by those skilled in the art within the scope of the present invention.
또한, 필요에 따라 기능적 물질, 예컨대, 미백제, 보습제, 항염증제, 항박테리아제, 항진 균제, 비타민, 자외선 차단제, 항생제, 여드름 방지제, 향수, 염료가 포함될 수도 있으며, 이들은 화장품 분야에서 통상적으로 사용되는 양으로 본 발명에 따른 화장용 조성물에 포함될 수 있다. 본 발명의 화장료는 그 기능적 효과를 증대시키기 위하여 본 발명의 조성물에 추가로 동일 또는 유사한 기능을 나타내는 보습 활성 성분을 1종 이상 함유할 수 있다.In addition, functional substances such as whitening agents, moisturizers, anti-inflammatory agents, antibacterial agents, antifungal agents, vitamins, sunscreens, antibiotics, anti-acne agents, perfumes, and dyes may be included as needed, and these may be included in amounts commonly used in the cosmetics field. It can be included in the cosmetic composition according to the present invention. In order to increase its functional effect, the cosmetic of the present invention may contain one or more types of moisturizing active ingredients that exhibit the same or similar functions as the composition of the present invention.
본 발명의 화장료 조성물로부터 제조되는 화장품은 일반적인 유화 제형 및 가용화 제형의 형태로 제조할 수 있다. 유화 제형의 화장품으로는 영양화장수, 크림, 에센스 등이 있으며, 가용화 제형의 화장품으로는 유연화장수가 있다. Cosmetics prepared from the cosmetic composition of the present invention can be manufactured in the form of general emulsified formulations and solubilized formulations. Cosmetics in emulsified formulations include nourishing lotions, creams, and essences, and cosmetics in solubilized formulations include flexible lotions.
상기 화장품은 본 발명의 조성물 이외에도 피부학적으로 허용된 매질 또는 기제를 함유함으로써 당업계에서 통상적으로 사용되는 국소 적용 또는 전신 적용할 수 있는 보조제 형태로 제조될 수도 있다. In addition to the composition of the present invention, the cosmetic product may also be manufactured in the form of an auxiliary agent commonly used in the art for topical or systemic application by containing a dermatologically acceptable medium or base.
적합한 화장품의 제형으로는 예를 들면, 용액, 겔, 고체 또는 반죽 무수 생성물, 수상에 유상을 분산시켜 얻은 에멀젼, 현탁액, 마이크로에멀젼, 마이크로캡슐, 미세과립구 또는 이온형(리포좀), 비이온형의 소낭 분산제의 형태, 크림, 스킨, 로션, 파우더, 연고, 스프레이 또는 콘실 스틱(conceal stick)의 형태로 제공될 수 있다. 또한, 포말 (foam)의 형태 또는 압축된 추진제를 더 함유한 에어로졸 조성물의 형태로도 제조될 수 있다. Suitable cosmetic formulations include, for example, solutions, gels, solid or pasty anhydrous products, emulsions obtained by dispersing the oil phase in the aqueous phase, suspensions, microemulsions, microcapsules, microgranules or in ionic (liposome) or non-ionic form. It may be provided in the form of a vesicular dispersion, cream, skin, lotion, powder, ointment, spray or conceal stick. Additionally, it can be prepared in the form of foam or in the form of an aerosol composition further containing compressed propellant.
본 발명의 화장료 조성물을 첨가할 수 있는 제품으로는, 예를 들어, 수렴화장수, 유연화장수, 영양화장수, 각종 크림, 에센스, 팩, 파운데이션 등과 같은 화장품류와 클렌징, 세안제, 비누, 트리트먼트 또는 미용액 등이 있다. 구체적인 제형으로서는 스킨로션, 스킨 소프너, 스킨토너, 아스트린젠트, 로션, 밀크로션, 모이스처 로션, 영양로션, 맛사지크림, 영양크림, 모이스처 크림, 핸드크림, 에센스, 영양에센스, 팩, 비누, 샴푸, 클렌징 폼, 클렌징로션, 클 렌징크림, 바디로션, 바디클렌저, 유액, 프레스파우더, 루스파우더 또는 아이섀도 등의 제형을 포함한다.Products to which the cosmetic composition of the present invention can be added include, for example, cosmetics such as astringent lotion, softening lotion, nourishing lotion, various creams, essences, packs, foundations, etc., and cleansers, face washes, soaps, treatments, or serums. etc. Specific formulations include skin lotion, skin softener, skin toner, astringent, lotion, milk lotion, moisture lotion, nutritional lotion, massage cream, nutritional cream, moisture cream, hand cream, essence, nutritional essence, pack, soap, shampoo, and cleansing foam. , cleansing lotion, cleansing cream, body lotion, body cleanser, emulsion, pressed powder, loose powder or eye shadow.
본 발명의 다른 일 실시예에 따른 식품 조성물은 상기 피부 보습용 조성물을 포함한다. A food composition according to another embodiment of the present invention includes the skin moisturizing composition.
이 때, 식품 또는 음료 중의 상기 추출물의 양은 전체 식품 중량의 약 0.01 내지 15 중량%로 가할 수 있으며, 건강음료 조성물은 100 ㎖를 기준으로 약 0.01 내지 10g의 비율로 가할 수 있으나, 이에 제한되지 않는다.At this time, the amount of the extract in the food or beverage can be added at about 0.01 to 15% by weight of the total weight of the food, and the health drink composition can be added at a rate of about 0.01 to 10g based on 100 ml, but is not limited thereto. .
본 발명의 식품 조성물이 음료 조성물인 경우, 지시된 비율로 필수 성분으로서 상기 추출물을 함유하는 외에는 다른 성분에는 특별한 제한이 없으며 통상의 음료와 같이 여러 가지 향미제 또는 천연 탄수화물 등을 추가 성분으로서 함유할 수 있다. 상술한 천연 탄수화물의 예는 모노사카라이드, 예를 들어, 포도당, 과당 등; 디사카라이드, 예를 들어 말토스, 슈크로스 등; 및 폴리사카라이드, 예를 들어 덱스트린, 시클로덱스트린 등과 같은 통상적인 당, 및 자일리톨, 소르비톨, 에리트리톨 등의 당알코올이다. 상술한 것 이외의 향미제로서 천연 향미제(타우마틴, 스테비아 추출물 (예를 들어 레바우디오시드 A, 글리시르히진등) 및 합성 향미제 (사카린, 아스파탐 등)를 사용할 수 있으나, 이에 제한되지 않을 수 있다. 상기 천연 탄수화물의 비율은 본 발명의 조성물 100 ㎖ 당 일반적으로 약 1 내지 20g의 범위일 수 있으나, 이에 제한되지 않을 수 있다.When the food composition of the present invention is a beverage composition, other than containing the extract as an essential ingredient in the ratio indicated, there are no particular restrictions on other ingredients, and various flavoring agents or natural carbohydrates may be contained as additional ingredients like ordinary beverages. You can. Examples of the above-mentioned natural carbohydrates include monosaccharides such as glucose, fructose, etc.; Disaccharides such as maltose, sucrose, etc.; and polysaccharides, such as common sugars such as dextrin and cyclodextrin, and sugar alcohols such as xylitol, sorbitol, and erythritol. As flavoring agents other than those mentioned above, natural flavoring agents (thaumatin, stevia extract (e.g., rebaudioside A, glycyrrhizin, etc.) and synthetic flavoring agents (saccharin, aspartame, etc.) can be used, but are not limited to these. The ratio of the natural carbohydrate may generally range from about 1 to 20 g per 100 ml of the composition of the present invention, but may not be limited thereto.
상기 외에 본 발명의 조성물은 여러 가지 영양제, 비타민, 광물 (전해질), 합성 풍미제 및 천연 풍미제 등의 풍미제, 착색제 및 중진제 (치즈, 초콜릿 등), 펙트산 및 그의 염, 알긴산 및 그의 염, 유기산, 보호성 콜로이드 증점제, pH 조절제, 안정화제, 방부제, 글리세린, 알코올, 탄산 음료에 사용되는 탄산화제 등을 함유할 수 있으나, 이에 제한되지 않을 수 있다.In addition to the above, the composition of the present invention contains various nutrients, vitamins, minerals (electrolytes), flavoring agents such as synthetic and natural flavors, colorants and thickening agents (cheese, chocolate, etc.), pectic acid and its salts, alginic acid and its It may contain salt, organic acid, protective colloidal thickener, pH adjuster, stabilizer, preservative, glycerin, alcohol, carbonating agent used in carbonated beverages, etc., but may not be limited thereto.
그 밖에 본 발명의 조성물은 천연 과일 주스 및 과일 주스 음료 및 야채 음료의 제조를 위한 과육을 함유할 수 있고, 이러한 성분은 독립적으로 또는 조합하여 사용할 수 있다. 이러한 첨가제의 비율은 중요하지는 않지만 본 발명의 조성물 100 중량부 당 약 0.1 내지 약 20 중량부의 범위에서 선택될 수 있으나, 이에 제한되지 않는다.In addition, the composition of the present invention may contain natural fruit juice and pulp for the production of fruit juice drinks and vegetable drinks, and these ingredients can be used independently or in combination. The proportion of these additives is not critical, but may be selected in the range of about 0.1 to about 20 parts by weight per 100 parts by weight of the composition of the present invention, but is not limited thereto.
본 발명의 또 다른 일 실시예에 따른 기능성 식품 조성물은 상기 피부 보습용 조성물을 포함하는 것일 수 있다.A functional food composition according to another embodiment of the present invention may include the skin moisturizing composition.
본 발명에서 말하는 기능성 식품은 건강보조의 목적으로 특정성분을 원료로 하거나 식품원료에 들어있는 특정성분을 추출, 농축, 정제, 혼합 등의 방법으로 제조, 가공한 식품으로 건강보조식품을 포함하며, 기타, 식품성분이 갖는 생체방어, 생체리듬의 조절, 질병의 방지와 회복 등 생체조절기능을 생체에 대하여 충분히 발휘할 수 있도록 설계되고 가공된 식품으로서, 질병의 예방 및 질병의 회복 등과 관련된 기능도 갖는 것을 모두 포함하는 것으로 한다.Functional foods as referred to in the present invention include health supplements, which are foods manufactured and processed using specific ingredients as raw materials or specific ingredients contained in food ingredients by methods such as extraction, concentration, purification, and mixing for the purpose of health supplementation, In addition, it is a food designed and processed to fully exert the bioregulatory functions of food ingredients, such as biodefense, regulation of biorhythm, prevention and recovery of disease, etc., and also has functions related to disease prevention and recovery from disease. Make sure to include everything.
본 발명은 카칼리아 추출물을 유효 성분으로 포함하는 피부 보습용 조성물로, 피부 자극이 없고, 피부 보습 효과가 우수한 조성물에 관한 것으로, 화장료 조성물로 제공되어, 피부에 도포 시 피부 자극이 없어, 피부 트러블의 발생을 유발하지 않고, 천연물질 유래 성분을 포함하여 환경성 피부 질환을 가지는 경우에도 사용이 가능하며, 우수한 피부 보습 효과를 나타낼 수 있다. The present invention relates to a skin moisturizing composition containing Cacalia extract as an active ingredient, which does not cause skin irritation and has an excellent skin moisturizing effect. It is provided as a cosmetic composition, and does not cause skin trouble when applied to the skin. It does not cause the occurrence of , can be used even in cases of environmental skin diseases as it contains ingredients derived from natural substances, and can have an excellent skin moisturizing effect.
또한, 식품 조성물로 제공되어, 섭취에 의한 피부 보습 효과를 나타낼 수 있다.Additionally, it can be provided as a food composition and have a skin moisturizing effect upon ingestion.
이하, 본 발명이 속하는 기술 분야에서 통상의 지식을 가진 자가 용이하게 실시할 수 있도록 본 발명의 실시예에 대하여 상세히 설명한다. 그러나 본 발명은 여러 가지 상이한 형태로 구현될 수 있으며 여기에서 설명하는 실시예에 한정되지 않는다.Hereinafter, embodiments of the present invention will be described in detail so that those skilled in the art can easily implement it. However, the present invention may be implemented in many different forms and is not limited to the embodiments described herein.
제조예Manufacturing example
카칼리아 추출물의 제조Preparation of Cacalia extract
카칼리아는 잎만 수득한 후, 이를 세척하고, 건조시킨 후, 분쇄하여 분쇄물로 제조하고, 동결 건조하였다. 동결 건조된 카칼리아 잎 3g을 15ml 튜브(tube)에 1mg을 넣고, 70% 에탄올(ethanol)을 10ml를 다시 넣었다. 시료를 rounded mixed machine에서 18시간동안 넣고 혼합 및 추출하였다. 추출 후 3000rpm, 10분 원심분리 후 상층액만 채취하였다. 이렇게 채취된 상층액에 포함된 에탄올(ethanol)을 40℃에서 증발하였다. 그리고 남은 시료는 동결건조하였다. 본 실험에 사용한 카칼리아 추출물(SE)은 카칼리아 원재료에서의 수득률이 11.5%로 추출하였다.After obtaining only the leaves of Cacalia, they were washed, dried, pulverized to produce pulverized powder, and freeze-dried. 1 mg of 3 g of freeze-dried Cacalia leaves was placed in a 15 ml tube, and 10 ml of 70% ethanol was added again. Samples were mixed and extracted in a rounded mixing machine for 18 hours. After extraction, centrifugation at 3000 rpm for 10 minutes was performed, and only the supernatant was collected. Ethanol contained in the supernatant collected in this way was evaporated at 40°C. And the remaining samples were freeze-dried. Caccalia extract (SE) used in this experiment was extracted from Cacalia raw materials with a yield of 11.5%.
발효 해조류 추출물의 제조Preparation of fermented seaweed extract
꼬시래기는 건조한 이후, 분쇄기를 이용하여 분쇄하였다. 분쇄한 꼬시래기에 Lactobacillus rhamnosus를 접종 후 25℃에 3일간 발효시켜 발효 꼬시래기를 제조하였다. 이후 카칼리아 추출물의 제조 방법과 동일한 방법으로 발효 꼬시래기 추출물(GE)을 제조하였다. After drying the sea snail, it was pulverized using a grinder. Fermented yellowtail was produced by inoculating the crushed yellowtail with Lactobacillus rhamnosus and fermenting it at 25°C for 3 days. Afterwards, fermented Brassica serrata extract (GE) was prepared in the same manner as the Cacalia extract preparation method.
발효 세모가사리 추출물(FE)은 발효 꼬시래기 추출물과 동일한 방법을 이용하여 제조하였다.Fermented Siberian snail extract (FE) was prepared using the same method as the fermented Siberian snail extract.
혼합 추출물의 제조Preparation of mixed extract
카칼리아 추출물(SE), 발효 꼬시래기 추출물(GE) 및 발효 세모가사리 추출물(FE)은 하기 표 1과 같이 혼합하여 사용하였다. Cacalia extract (SE), fermented Red-eared cypress extract (GE), and fermented Trifolium vulgaris extract (FE) were mixed and used as shown in Table 1 below.
(단위 중량부)(unit weight)
실험예 1Experimental Example 1
피부 자극 실험skin irritation test
과거력상 피부자극에 과민반응을 보인 적이 없으며, 현재 피부병 내지 피부 알러지 증상이 없는 20, 30대 여성 15명을 대상으로 인체 피부 첩포시험을 통하여 자극 완화 효과를 확인하였다. 피부 자극 물질인 락틱산 1.0중량%를 자극원으로 첨가한 실시예 및 비교예를 사용하였다. The irritation-relieving effect was confirmed through a human skin patch test on 15 women in their 20s and 30s who had never shown hypersensitivity to skin irritation in the past and had no current skin disease or skin allergy symptoms. Examples and comparative examples in which 1.0% by weight of lactic acid, a skin irritant, was added as an irritant were used.
우선 참가자의 시험에 70 중량% 에탄올을 이용하여 세정 후 건조하였다. 준비된 시험물질을 15 ㎍씩 핀챔버(Finn chamber, 100x10, EPITEST, 핀란드) 내에 적하시킨 후 시험 대상자의 전박(forearm) 안쪽 부위에 밀폐 첩포하였다. 24시간 동안 첩포하고 첩포를 제거한 후 마킹펜으로 시험부위를 표시하였다. 표시 후 각각 1시간 및 24시간 후에 확대경(8MC-150, DAZOR, 미국)을 이용하여 시험 부위를 관찰하여 홍반 및 부종 유무를 관찰하였다. First, the participant's test was washed with 70% by weight ethanol and dried. 15 ㎍ of the prepared test substance was dropped into a Finn chamber (100x10, EPITEST, Finland) and then sealed and applied to the inside of the test subject's forearm. The patch was applied for 24 hours, the patch was removed, and the test area was marked with a marking pen. One hour and 24 hours after marking, the test area was observed using a magnifying glass (8MC-150, DAZOR, USA) to observe the presence or absence of erythema and edema.
피부 반응은 표 2의 국제접촉피부염연구회 (ICDRG, InternationalContact Dermatitis Research Group)의 규정에 따라 판정하였으며, 그 결과는 표 3과 같다.Skin reactions were determined according to the regulations of the International Contact Dermatitis Research Group (ICDRG) in Table 2, and the results are shown in Table 3.
[수학식 1][Equation 1]
평균피부반응도 (mean response rate)=(점수 x 반응 수 x 100 x 1/2)/[3(최대 점수) x 총피검자수(n)]Mean skin response rate = (score x number of reactions x 100 x 1/2)/[3 (maximum score) x total number of subjects (n)]
상기 실험 결과에 따르면 카칼리아 추출물을 사용하는 경우 피부 자극이 발생하지 않았으며, 발효 꼬시래기 추출물 및 발효 세모가사리 추출물을 사용한 경우에도 피부 자극이 심하게 발생하지 않음을 확인하였다. 다만, 복합 추출물의 경우, 특정 범위내에서 혼합하여 사용 시, 추출물 간의 혼합 사용에 따른 상승 작용으로 인해, 사용 시에 가장 우수한 피부 자극 완화 효과가 나타남을 확인하였다. According to the above experimental results, it was confirmed that skin irritation did not occur when using the Cacalia extract, and that skin irritation did not occur significantly even when using the fermented Corolla extract and the fermented Semogasari extract. However, in the case of complex extracts, it was confirmed that when mixed and used within a certain range, the best skin irritation relief effect was observed due to the synergistic effect of the mixed use of extracts.
실험예 2Experimental Example 2
보습 효과 실험Moisturizing effect experiment
수분 보유능의 측정수분 보유능 측정은 Corneometer (Courage + Khazaka, GmbH, Germany)를 사용하여 피부 표면의 전기 전도도를 측정하였으며, 측정온도는 25℃, 45% 상대습도를 유지하는 항온항습실에서 실시예 및 비교예에서 제조된 각 화장료를 15명의 피시험자 하박 안쪽에 일정량 (0.03g/16cm2)을 도포하고 도포 전 및 도포 2시간 후의 피부의 수분함량을 측정하였으며, 아무런 처리를 하지 않은 정상 피부를 대조군으로 사용하였다. 그 결과는 다음 표 4와 같다.Measurement of water retention capacity The electrical conductivity of the skin surface was measured using a Corneometer (Courage + Khazaka, GmbH, Germany), and the measurement temperature was 25°C and 45% relative humidity was maintained in a constant temperature and humidity room. Examples and comparisons A certain amount (0.03g/16cm 2 ) of each cosmetic product prepared in the example was applied to the inside of the lower arm of 15 test subjects, and the moisture content of the skin was measured before and 2 hours after application. Normal skin without any treatment was used as the control group. used. The results are shown in Table 4 below.
상기 실험 결과에 따르면 카칼리아 추출물을 사용한 경우, 2시간 경과 후에도 우수한 피부 보습 효과가 나타나며, 복합 추출물로 사용 시 특정 범위 내에서 우수한 피부 보습 효과가 나타남을 확인하였다. According to the above experimental results, it was confirmed that when using the Cacalia extract, an excellent skin moisturizing effect was observed even after 2 hours, and when used as a complex extract, an excellent skin moisturizing effect was observed within a certain range.
실험예 3Experimental Example 3
피부 발림성 평가Skin applicability evaluation
상기 실시예 및 비교예 조성물을 이용하여 화장 크림으로 제조하고, 이의 발림성을 평가하였다. A cosmetic cream was prepared using the compositions of the examples and comparative examples above, and its spreadability was evaluated.
상기 실시예 및 비교예 조성물 각 3 중량%, 아스코르빈산-2-인산마그네슘 1 중량%, 수용성 콜라겐(1% 수용액) 1 중량%, 시트르산나트륨 0.01 중량%, 시트르산 0.05 중량%, 1,3-부틸렌글리콜 3 중량% 및 나머지 정제수를 혼합하여 크림으로 제조하고, 20, 30대 여성 15명에게 6개의 제품을 제공한 후, 피부 발림성에 대한 상대적인 평가를 요청하였다. 1 내지 5점으로 평가를 요청하였으며 점수가 높을수록 우수한 제품을 의미한다. 3% by weight of each of the above Example and Comparative Example compositions, 1% by weight of magnesium ascorbic acid-2-phosphate, 1% by weight of water-soluble collagen (1% aqueous solution), 0.01% by weight of sodium citrate, 0.05% by weight of citric acid, 1,3- A cream was prepared by mixing 3% by weight of butylene glycol and the remaining purified water. Six products were provided to 15 women in their 20s and 30s, and a relative evaluation of their applicability to the skin was requested. Evaluation was requested from 1 to 5 points, with higher scores indicating better products.
상기 평가 결과에 따르면, 카칼리아 추출물만 포함한 크림에서는 발림성이 중간 정도로 평가되었으나, 복합 추출물을 이용한 경우, 매우 우수한 발림성을 나타내어, 기호도가 높은 크림으로의 제공 가능성이 높였다. According to the above evaluation results, the cream containing only the Cacalia extract was evaluated as having medium spreadability, but when the complex extract was used, the cream had excellent spreadability, increasing the possibility of providing the cream with a high preference.
이상에서 본 발명의 바람직한 실시예에 대하여 상세하게 설명하였지만 본 발명의 권리범위는 이에 한정되는 것은 아니고 다음의 청구범위에서 정의하고 있는 본 발명의 기본 개념을 이용한 당업자의 여러 변형 및 개량 형태 또한 본 발명의 권리범위에 속하는 것이다.Although the preferred embodiments of the present invention have been described in detail above, the scope of the present invention is not limited thereto, and various modifications and improvements made by those skilled in the art using the basic concept of the present invention defined in the following claims are also possible. falls within the scope of rights.
Claims (7)
피부 보습용 조성물.Contains Cacalia leaf extract as an active ingredient
Composition for skin moisturizing.
상기 조성물은 피부 자극이 없고, 피부 보습 효과가 우수한
피부 보습용 조성물.According to paragraph 1,
The composition does not irritate the skin and has an excellent skin moisturizing effect.
Composition for skin moisturizing.
상기 추출물은 물, 탄소수 1 내지 6의 저급 알코올 및 이들의 혼합물로 이루어진 군으로부터 선택되는 어느 하나를 추출 용매로 하여 추출된 것인
피부 보습용 조성물.According to paragraph 1,
The extract is extracted using any one selected from the group consisting of water, lower alcohols having 1 to 6 carbon atoms, and mixtures thereof as an extraction solvent.
Composition for skin moisturizing.
상기 조성물은 발효 꼬시래기 추출물 및 발효 세모가사리 추출물을 추가로 포함하는
피부 보습용 조성물.According to paragraph 1,
The composition further comprises a fermented snail extract and a fermented cypress extract.
Composition for skin moisturizing.
피부 보습용 화장료 조성물.Containing the skin moisturizing composition according to any one of claims 1 to 4.
Cosmetic composition for skin moisturizing.
상기 화장료 조성물은 스킨, 세럼, 로션, 에멀전, 크림, 에센스, 화장수, 파운데이션, 팩, 비누, 계면활성제-함유 클렌징, 스프레이 및 파우더로 구성된 군으로부터 선택된 제형인
피부 보습용 화장료 조성물.According to clause 5,
The cosmetic composition is a formulation selected from the group consisting of skin, serum, lotion, emulsion, cream, essence, lotion, foundation, pack, soap, surfactant-containing cleansing, spray, and powder.
Cosmetic composition for skin moisturizing.
기능성 식품 조성물.Containing the skin moisturizing composition according to any one of claims 1 to 4.
Functional food composition.
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