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IT1306205B1 - Macrolidi ad attivita' antiinfiammatoria. - Google Patents

Macrolidi ad attivita' antiinfiammatoria.

Info

Publication number
IT1306205B1
IT1306205B1 IT1999MI000061A ITMI990061A IT1306205B1 IT 1306205 B1 IT1306205 B1 IT 1306205B1 IT 1999MI000061 A IT1999MI000061 A IT 1999MI000061A IT MI990061 A ITMI990061 A IT MI990061A IT 1306205 B1 IT1306205 B1 IT 1306205B1
Authority
IT
Italy
Prior art keywords
inflammatory activity
macrolids
oxyimino
macrolides
endowed
Prior art date
Application number
IT1999MI000061A
Other languages
English (en)
Inventor
Franco Pellacini
Daniela Botta
Stefano Romagnano
Ermanno Moriggi
Lorenzo Pradella
Original Assignee
Zambon Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to IT1999MI000061A priority Critical patent/IT1306205B1/it
Application filed by Zambon Spa filed Critical Zambon Spa
Priority to MXPA01007164A priority patent/MXPA01007164A/es
Priority to EP00904899A priority patent/EP1144427B1/en
Priority to RU2001118831/04A priority patent/RU2243230C2/ru
Priority to JP2000593622A priority patent/JP4568433B2/ja
Priority to PCT/EP2000/000163 priority patent/WO2000042055A2/en
Priority to ES00904899T priority patent/ES2251966T3/es
Priority to HU0105105A priority patent/HU229228B1/hu
Priority to AT00904899T priority patent/ATE308552T1/de
Priority to SK981-2001A priority patent/SK286772B6/sk
Priority to DE60023647T priority patent/DE60023647T2/de
Priority to BR0007514-0A priority patent/BR0007514A/pt
Priority to CA002368400A priority patent/CA2368400C/en
Priority to CNB008027676A priority patent/CN1151165C/zh
Priority to IL14404400A priority patent/IL144044A0/xx
Priority to AU26636/00A priority patent/AU769006B2/en
Publication of ITMI990061A1 publication Critical patent/ITMI990061A1/it
Priority to US09/889,284 priority patent/US6455576B1/en
Publication of IT1306205B1 publication Critical patent/IT1306205B1/it
Application granted granted Critical
Priority to IL144044A priority patent/IL144044A/en
Priority to ZA200105748A priority patent/ZA200105748B/en
Priority to NO20013517A priority patent/NO318982B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Rheumatology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
IT1999MI000061A 1999-01-15 1999-01-15 Macrolidi ad attivita' antiinfiammatoria. IT1306205B1 (it)

Priority Applications (20)

Application Number Priority Date Filing Date Title
IT1999MI000061A IT1306205B1 (it) 1999-01-15 1999-01-15 Macrolidi ad attivita' antiinfiammatoria.
CA002368400A CA2368400C (en) 1999-01-15 2000-01-12 Macrolides with anti-inflammatory activity
EP00904899A EP1144427B1 (en) 1999-01-15 2000-01-12 Macrolides with anti-inflammatory activity
JP2000593622A JP4568433B2 (ja) 1999-01-15 2000-01-12 抗炎症活性を有するマクロライド
PCT/EP2000/000163 WO2000042055A2 (en) 1999-01-15 2000-01-12 Macrolides with anti-inflammatory activity
ES00904899T ES2251966T3 (es) 1999-01-15 2000-01-12 Macrolidos con actividad anti-inflamatoria.
HU0105105A HU229228B1 (en) 1999-01-15 2000-01-12 Macrolides with anti-inflammatory activity
AT00904899T ATE308552T1 (de) 1999-01-15 2000-01-12 Makrolide mit entzündungshemmender wirkung
CNB008027676A CN1151165C (zh) 1999-01-15 2000-01-12 具有抗炎活性的大环内酯
DE60023647T DE60023647T2 (de) 1999-01-15 2000-01-12 Makrolide mit entzündungshemmender wirkung
MXPA01007164A MXPA01007164A (es) 1999-01-15 2000-01-12 Macrolidos con actividad anti-inflamatoria.
RU2001118831/04A RU2243230C2 (ru) 1999-01-15 2000-01-12 Макролиды и фармацевтический состав на их основе
SK981-2001A SK286772B6 (sk) 1999-01-15 2000-01-12 Makrolidy, farmaceutický prostriedok s ich obsahom a ich použitie
IL14404400A IL144044A0 (en) 1999-01-15 2000-01-12 Macrolides with anti-inflammatory activity
AU26636/00A AU769006B2 (en) 1999-01-15 2000-01-12 Macrolides with anti-inflammatory activity
BR0007514-0A BR0007514A (pt) 1999-01-15 2000-01-12 Macrolìdeos com atividade anti-inflamatória
US09/889,284 US6455576B1 (en) 1999-01-15 2001-01-12 Macrolides with anti-inflammatory activity
IL144044A IL144044A (en) 1999-01-15 2001-06-28 Anti- inflammatory 3' - de (dimethylamino) - erythromycin a-9-oxime derivatives and pharmaceutical compositions containing them
ZA200105748A ZA200105748B (en) 1999-01-15 2001-07-12 Macrolides with anti-inflammatory activity.
NO20013517A NO318982B1 (no) 1999-01-15 2001-07-16 Makrolider med anti-inflammatorisk aktivitet, farmasoytisk sammensetning som inneholder disse og anvendelse av 3'-desdimetylamino-3', 4'-dehydroerytromycin A- oksim og 3'-desdimetylamino-3', 4'dehydroerytromycin A-9-O-metyloksim som anti-inflammatoriske forbindelser

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT1999MI000061A IT1306205B1 (it) 1999-01-15 1999-01-15 Macrolidi ad attivita' antiinfiammatoria.

Publications (2)

Publication Number Publication Date
ITMI990061A1 ITMI990061A1 (it) 2000-07-15
IT1306205B1 true IT1306205B1 (it) 2001-05-30

Family

ID=11381492

Family Applications (1)

Application Number Title Priority Date Filing Date
IT1999MI000061A IT1306205B1 (it) 1999-01-15 1999-01-15 Macrolidi ad attivita' antiinfiammatoria.

Country Status (19)

Country Link
US (1) US6455576B1 (it)
EP (1) EP1144427B1 (it)
JP (1) JP4568433B2 (it)
CN (1) CN1151165C (it)
AT (1) ATE308552T1 (it)
AU (1) AU769006B2 (it)
BR (1) BR0007514A (it)
CA (1) CA2368400C (it)
DE (1) DE60023647T2 (it)
ES (1) ES2251966T3 (it)
HU (1) HU229228B1 (it)
IL (2) IL144044A0 (it)
IT (1) IT1306205B1 (it)
MX (1) MXPA01007164A (it)
NO (1) NO318982B1 (it)
RU (1) RU2243230C2 (it)
SK (1) SK286772B6 (it)
WO (1) WO2000042055A2 (it)
ZA (1) ZA200105748B (it)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HRP20010018A2 (en) 2001-01-09 2002-12-31 Pliva D D Novel anti-inflammatory compounds
RU2330858C2 (ru) 2002-07-08 2008-08-10 Глаксомитклайн Истраживацки Центар Загреб Д.О.О. Новые соединения, составы и способы лечения воспалительных заболеваний и состояний
RS20050007A (en) * 2002-07-08 2007-09-21 Glaxo Smith Kline Istraživački Centar Zagreb D.O.O., Novel nonsteroidal anti- inflammatory substances, compositions and methods for their use
AU2003264917A1 (en) 2002-07-08 2004-01-23 Pliva - Istrazivacki Institut D.O.O. Hybrid molecules of macrolides with steroid/non-steroid anti-inflammatory, antineoplastic and antiviral active molecules
ITMI20021726A1 (it) * 2002-08-01 2004-02-02 Zambon Spa Macrolidi ad attivita' antiinfiammatoria.
TW200420573A (en) 2002-09-26 2004-10-16 Rib X Pharmaceuticals Inc Bifunctional heterocyclic compounds and methods of making and using same
ITMI20022292A1 (it) * 2002-10-29 2004-04-30 Zambon Spa 9a-azalidi ad attivita' antiinfiammatoria.
US7410952B2 (en) 2003-04-17 2008-08-12 Sandoz Ag Derivatives of azithromycin
HRP20030324A2 (en) 2003-04-24 2005-02-28 Pliva-Istra�iva�ki institut d.o.o. Compounds of antiinflammatory effect
ITMI20040124A1 (it) 2004-01-29 2004-04-29 Zambon Spa Macrolidi ad attivita' antiinfiammatoria
WO2006130128A2 (en) * 2004-02-18 2006-12-07 Chiron Corporation Methods of identifying anti-inflammatory macrolides
CN102816194A (zh) 2004-02-27 2012-12-12 瑞伯-X医药品有限公司 大环化合物以及其制作和使用方法
WO2006035301A2 (en) * 2004-09-27 2006-04-06 Ranbaxy Laboratories Limited Erythromycin a derivatives as antibacterial agents
CA2585711A1 (en) 2004-10-27 2006-05-04 Glaxosmithkline Istrazivacki Centar Zagreb D.O.O. Conjugates with anti-inflammatory activity
US20080249034A1 (en) * 2005-03-21 2008-10-09 Zambon S.P.A. Use of Macrolides for Treating Intestinal Inflammation
US7582611B2 (en) * 2005-05-24 2009-09-01 Pfizer Inc. Motilide compounds
US20110178287A1 (en) 2010-01-19 2011-07-21 Cerulean Pharma Inc. Cyclodextrin-based polymers for therapeutic delivery
RU2455309C2 (ru) * 2010-07-20 2012-07-10 Открытое Акционерное Общество "Татхимфармпрепараты" Способ получения аморфной формы рокситромицина
GB201608236D0 (en) 2016-05-11 2016-06-22 Fidelta D O O Seco macrolide compounds
AU2021241591A1 (en) 2020-03-24 2022-10-20 Michael W. BURNET Anti-infective and anti-viral compounds and compositions

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3928387A (en) * 1974-02-04 1975-12-23 Hoffmann La Roche Antibiotic 1745A/X and methods for the production thereof
IT1189285B (it) * 1982-05-28 1988-02-04 Nuovo Consor Sanitar Nazionale Sali dell'antibiotico eritromicina e del suo estere propionico con acidi ad attivita' terapeutica coadiuvante
EP0254534A3 (en) * 1986-07-24 1991-04-17 William S. Robinson Erythromycin derivatives and compositions and use for inhibiting virus replication and disease
IT1276901B1 (it) * 1994-12-13 1997-11-03 Zambon Spa Derivati dell'eritromicina a 9-0-ossina dotati di attivita' antibiotica
KR19980701895A (ko) * 1995-03-08 1998-06-25 이라우치지마 가즈다카 면역관련병 처치제 및 그의 탐색 방법

Also Published As

Publication number Publication date
RU2243230C2 (ru) 2004-12-27
NO20013517D0 (no) 2001-07-16
CN1151165C (zh) 2004-05-26
HUP0105105A2 (hu) 2002-04-29
CA2368400A1 (en) 2000-07-20
IL144044A0 (en) 2002-04-21
WO2000042055A2 (en) 2000-07-20
CA2368400C (en) 2007-06-05
WO2000042055A3 (en) 2001-09-07
BR0007514A (pt) 2001-11-20
MXPA01007164A (es) 2002-03-27
US6455576B1 (en) 2002-09-24
ATE308552T1 (de) 2005-11-15
EP1144427A3 (en) 2002-08-28
SK286772B6 (sk) 2009-05-07
HU229228B1 (en) 2013-09-30
IL144044A (en) 2006-12-31
NO318982B1 (no) 2005-05-30
DE60023647D1 (de) 2005-12-08
ZA200105748B (en) 2002-10-14
HUP0105105A3 (en) 2003-05-28
SK9812001A3 (en) 2002-01-07
EP1144427A2 (en) 2001-10-17
ES2251966T3 (es) 2006-05-16
ITMI990061A1 (it) 2000-07-15
NO20013517L (no) 2001-07-16
JP4568433B2 (ja) 2010-10-27
DE60023647T2 (de) 2006-08-10
JP2002534531A (ja) 2002-10-15
EP1144427B1 (en) 2005-11-02
AU769006B2 (en) 2004-01-15
AU2663600A (en) 2000-08-01
CN1336932A (zh) 2002-02-20

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