[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

ITMI20022292A1 - 9a-azalidi ad attivita' antiinfiammatoria. - Google Patents

9a-azalidi ad attivita' antiinfiammatoria.

Info

Publication number
ITMI20022292A1
ITMI20022292A1 IT002292A ITMI20022292A ITMI20022292A1 IT MI20022292 A1 ITMI20022292 A1 IT MI20022292A1 IT 002292 A IT002292 A IT 002292A IT MI20022292 A ITMI20022292 A IT MI20022292A IT MI20022292 A1 ITMI20022292 A1 IT MI20022292A1
Authority
IT
Italy
Prior art keywords
inflammatory activity
azalids
azalides
cladinose
macrolides
Prior art date
Application number
IT002292A
Other languages
English (en)
Inventor
Gabriele Morazzoni
Ermanno Moriggi
Mauro Napoletano
Fernando Ornaghi
Franco Pellacini
Original Assignee
Zambon Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zambon Spa filed Critical Zambon Spa
Priority to IT002292A priority Critical patent/ITMI20022292A1/it
Priority to CNB2003801023509A priority patent/CN100486985C/zh
Priority to DE60303967T priority patent/DE60303967D1/de
Priority to AU2003276214A priority patent/AU2003276214B2/en
Priority to PCT/EP2003/012071 priority patent/WO2004039821A1/en
Priority to RU2005116248/04A priority patent/RU2320668C2/ru
Priority to EP03809747A priority patent/EP1556397B1/en
Priority to CA2502347A priority patent/CA2502347C/en
Priority to US10/531,462 priority patent/US7419961B2/en
Priority to JP2004547618A priority patent/JP4536516B2/ja
Priority to AT03809747T priority patent/ATE319729T1/de
Publication of ITMI20022292A1 publication Critical patent/ITMI20022292A1/it
Priority to IL167882A priority patent/IL167882A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Biochemistry (AREA)
  • Vascular Medicine (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Biotechnology (AREA)
  • Pain & Pain Management (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
IT002292A 2002-10-29 2002-10-29 9a-azalidi ad attivita' antiinfiammatoria. ITMI20022292A1 (it)

Priority Applications (12)

Application Number Priority Date Filing Date Title
IT002292A ITMI20022292A1 (it) 2002-10-29 2002-10-29 9a-azalidi ad attivita' antiinfiammatoria.
RU2005116248/04A RU2320668C2 (ru) 2002-10-29 2003-10-28 9а-азалиды с противовоспалительной активностью
DE60303967T DE60303967D1 (de) 2002-10-29 2003-10-28 9a-azalide mit entzündungshemmender wirkung
AU2003276214A AU2003276214B2 (en) 2002-10-29 2003-10-28 9a-azalides with anti-inflammatory activity
PCT/EP2003/012071 WO2004039821A1 (en) 2002-10-29 2003-10-28 9a-azalides with anti-inflammatory activity
CNB2003801023509A CN100486985C (zh) 2002-10-29 2003-10-28 具有抗炎活性的9a-氮杂内酯类
EP03809747A EP1556397B1 (en) 2002-10-29 2003-10-28 9a-azalides with anti-inflammatory activity
CA2502347A CA2502347C (en) 2002-10-29 2003-10-28 9a-azalides with anti-inflammatory activity
US10/531,462 US7419961B2 (en) 2002-10-29 2003-10-28 9a-azalides with anti-inflammatory activity
JP2004547618A JP4536516B2 (ja) 2002-10-29 2003-10-28 抗炎症性活性を有する９ａ−アザライド
AT03809747T ATE319729T1 (de) 2002-10-29 2003-10-28 9a-azalide mit entzündungshemmender wirkung
IL167882A IL167882A (en) 2002-10-29 2005-04-06 9a-AZALIDES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT002292A ITMI20022292A1 (it) 2002-10-29 2002-10-29 9a-azalidi ad attivita' antiinfiammatoria.

Publications (1)

Publication Number Publication Date
ITMI20022292A1 true ITMI20022292A1 (it) 2004-04-30

Family

ID=32211389

Family Applications (1)

Application Number Title Priority Date Filing Date
IT002292A ITMI20022292A1 (it) 2002-10-29 2002-10-29 9a-azalidi ad attivita' antiinfiammatoria.

Country Status (12)

Country Link
US (1) US7419961B2 (it)
EP (1) EP1556397B1 (it)
JP (1) JP4536516B2 (it)
CN (1) CN100486985C (it)
AT (1) ATE319729T1 (it)
AU (1) AU2003276214B2 (it)
CA (1) CA2502347C (it)
DE (1) DE60303967D1 (it)
IL (1) IL167882A (it)
IT (1) ITMI20022292A1 (it)
RU (1) RU2320668C2 (it)
WO (1) WO2004039821A1 (it)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20021726A1 (it) * 2002-08-01 2004-02-02 Zambon Spa Macrolidi ad attivita' antiinfiammatoria.
US7601695B2 (en) 2003-03-10 2009-10-13 Optimer Pharmaceuticals, Inc. Antibacterial agents
WO2006077501A2 (en) * 2005-01-13 2006-07-27 Glaxosmithkline Istrazivacki Centar Zagreb D.O.O. Decladinosyl-macrolides with anti-inflammatory activity
US20080200403A1 (en) * 2005-01-14 2008-08-21 Glaxosmithkline 9A-Carbamoyl and Thiocarbamoyl Azalides with Anti-Inflammatory Activity
EP2012776A2 (en) * 2006-05-03 2009-01-14 GlaxoSmithKline istrazivacki centar Zagreb d.o.o. 9a-substituted azalides
WO2009055557A1 (en) 2007-10-25 2009-04-30 Cempra Pharmaceuticals, Inc. Process for the preparation of macrolide antibacterial agents
EP3031460A1 (en) 2008-10-24 2016-06-15 Cempra Pharmaceuticals Inc. Biodefenses using triazole-containing macrolides
US9937194B1 (en) * 2009-06-12 2018-04-10 Cempra Pharmaceuticals, Inc. Compounds and methods for treating inflammatory diseases
EP2475253B1 (en) 2009-09-10 2016-10-26 Cempra Pharmaceuticals, Inc. Methods for treating malaria, tuberculosis and mac diseases
DK2550286T3 (en) 2010-03-22 2016-02-29 Cempra Pharmaceuticals Inc CRYSTALLINE FORMS OF A MACROLID AND APPLICATIONS THEREOF
US9051346B2 (en) 2010-05-20 2015-06-09 Cempra Pharmaceuticals, Inc. Process for preparing triazole-containing ketolide antibiotics
KR20180110181A (ko) 2010-09-10 2018-10-08 셈프라 파마슈티컬스, 인크. 질환을 치료하기 위한 수소결합 형성 플루오로 케토라이드
MX2014011537A (es) 2012-03-27 2015-02-10 Cempra Pharmaceuticals Inc Formulaciones parenterales para la administracion de antibioticos macrolidos.
RU2015138796A (ru) 2013-03-14 2017-04-19 Семпра Фармасьютикалс, Инк. Способы и составы для лечения респираторных заболеваний
EP2968384A4 (en) 2013-03-15 2017-02-15 Cempra Pharmaceuticals, Inc. Convergent processes for preparing macrolide antibacterial agents
WO2014166503A1 (en) * 2013-04-10 2014-10-16 Probiotic Pharmaceuticals Aps Azithromycin antimicrobial derivatives with non-antibiotic pharmaceutical effect
GB201520419D0 (en) 2015-11-19 2016-01-06 Epi Endo Pharmaceuticals Ehf Compounds
MX2021003808A (es) 2018-10-02 2021-05-27 Lunella Biotech Inc Derivados de azitromicina y roxitromicina como farmacos senoliticos.

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1100504A (en) * 1967-08-16 1968-01-24 Pliva Pharm & Chem Works Erythromycin oxime and 9-amino-3-o-cladinosyl-5-o-desosaminyl-6,11,12-trihydroxy-2,4,6,8,10,12-hexamethylpentadecane-13-olide
US3928387A (en) * 1974-02-04 1975-12-23 Hoffmann La Roche Antibiotic 1745A/X and methods for the production thereof
SI7910768A8 (en) * 1979-04-02 1996-06-30 Pliva Pharm & Chem Works Process for pripering 11-aza-4-0-cladinosyl-6-0-desosaminyl-15-ethyl- 7,13,14-trihydroxy-3,5,7,9,12,14-hexamethyl- oxacyclopentadecane-2-one and their derivatives
YU43006B (en) 1981-03-06 1989-02-28 Pliva Pharm & Chem Works Process for preparing n-methyl-11-aza-10-deoxo-10-dihydro erythromycin and derivatives thereof
US4464527A (en) * 1983-06-30 1984-08-07 Pfizer Inc. Antibacterial 9-deoxo-9a-alkyl-9a-aza-9a-homoerythromycin A derivatives and intermediates therefore
DE3860503D1 (de) * 1987-09-03 1990-10-04 Pliva Pharm & Chem Works 10-dihydro-10-deoxo-11-azaerythronolid-a-verbindungen,verfahren und zwischenprodukte zu ihrer herstellung und ihre verwendung in arzneimitteln und in deren herstellung.
SI9011409A (en) * 1990-07-18 1995-10-31 Pliva Pharm & Chem Works O-methyl azitromycin derivates, methods and intermediates for their preparation and methods for preparation of pharmaceuticals products which comprise them
WO1992016226A1 (en) 1991-03-19 1992-10-01 Smithkline Beecham Corporation Il-1 inhibitors
FR2691464B1 (fr) * 1992-05-21 1995-06-02 Roussel Uclaf Nouveaux dérivés de la 1-oxa 6-azacyclopentadécane 13,15-dione, leur procédé de préparation et leur application comme médicaments.
CN1159757A (zh) 1994-08-12 1997-09-17 大正制药株式会社 抑制白细胞介素5产生的抑制剂
EP0775489A4 (en) 1994-08-12 1998-05-06 Taisho Pharmaceutical Co Ltd INTERLEUKIN-5 PRODUCTION INHIBITOR
WO1999000124A1 (en) * 1997-06-26 1999-01-07 Merck & Co., Inc. 9a-azalides, compositions containing such compounds and methods of treatment
NZ503897A (en) * 1997-10-16 2002-10-25 Pliva Pharm & Chem Works 3,6-hemiketals from the class of 9a-azalides
EP0941998B1 (en) * 1998-03-03 2004-09-01 Pfizer Products Inc. 3,6-ketal macrolide antibiotics
US6262030B1 (en) * 1998-11-03 2001-07-17 Pfizer Inc. Erythromycin derivatives
IT1306205B1 (it) 1999-01-15 2001-05-30 Zambon Spa Macrolidi ad attivita' antiinfiammatoria.

Also Published As

Publication number Publication date
JP4536516B2 (ja) 2010-09-01
CA2502347A1 (en) 2004-05-13
US20060166904A1 (en) 2006-07-27
US7419961B2 (en) 2008-09-02
JP2006513157A (ja) 2006-04-20
ATE319729T1 (de) 2006-03-15
EP1556397A1 (en) 2005-07-27
CN1708507A (zh) 2005-12-14
CA2502347C (en) 2011-06-28
EP1556397B1 (en) 2006-03-08
IL167882A (en) 2010-06-30
CN100486985C (zh) 2009-05-13
RU2320668C2 (ru) 2008-03-27
WO2004039821A1 (en) 2004-05-13
DE60303967D1 (de) 2006-05-04
AU2003276214B2 (en) 2009-05-28
AU2003276214A1 (en) 2004-05-25
RU2005116248A (ru) 2006-01-20

Similar Documents

Publication Publication Date Title
ITMI20021726A1 (it) Macrolidi ad attivita' antiinfiammatoria.
ITMI20022292A1 (it) 9a-azalidi ad attivita' antiinfiammatoria.
NO2017047I1 (no) Tofacitinib, evt. i form av et farmasøytisk akseptabelt salt, inkludert citratsalt
IL163552A (en) Conjugates of biologically active compounds, uses thereof and pharmaceutical compositions comprising the same
ATE374016T1 (de) Tablette mit hohem wirkstoffgehalt
DK1183014T3 (da) Smagsmaskerede orale farmaceutiske sammensætninger med kontrolleret frigivelse
TR200003787A3 (tr) Kararli yavas salimli oral dozaj bilesimi.
CO5050297A1 (es) Uso de peg-ifn-alfa y ribavirina para el tratamiento de hepatitis c cronica
BR0115810B1 (pt) composições cosméticas, dermatológicas e farmacêuticas isentas de tensoativos.
ITTO20010005A1 (it) Formulazione farmaceutica.
SE0003449D0 (sv) Anticancer compositions
IS6263A (is) Lyfjasamsetningar, sem innihalda trípeptíð
DK1526839T3 (da) Orale farmaceutiske former for flydende lægemidler med forbedret biotilgængelighed
NO992102L (no) Peptidblanding, samt farmasøytisk sammensetning og kreftvaksine som innbefatter peptidblandingen
BR0008228A (pt) Composições de n-benzoil estaurosporinaespontaneamente dispersìveis
PT1121127E (pt) Composicoes farmaceuticas orais contendo buprenorfina
BR0112847A (pt) Uso de uma forma de dosagem sólida
IS2258B (is) Setin tríasóló-pýridasín afleiða, lyfjasamsetningar gerðar úr henni
ITMI20021725A1 (it) Composizioni farmaceutiche ad attivita' antibiotica.
DE69915487D1 (de) Erythromycin-derivate mit antibiotischer wirkung
ITRM20030363A0 (it) Composizioni comprendenti la 3, 5diiodotironina e uso farmaceutico diesse.
SE0001916D0 (sv) Novel formulation
ATE279180T1 (de) Feste pharmazeutische zubereitungen mit nanosols aus chitosan, sowie deren herstellung
MA26677A1 (fr) Medicaments antiparkinsoniens.
DE60312642D1 (de) Pharmazeutische zusammensetzung mit modifizierter freisetzung