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DE60023647D1 - Makrolide mit entzündungshemmender wirkung - Google Patents

Makrolide mit entzündungshemmender wirkung

Info

Publication number
DE60023647D1
DE60023647D1 DE60023647T DE60023647T DE60023647D1 DE 60023647 D1 DE60023647 D1 DE 60023647D1 DE 60023647 T DE60023647 T DE 60023647T DE 60023647 T DE60023647 T DE 60023647T DE 60023647 D1 DE60023647 D1 DE 60023647D1
Authority
DE
Germany
Prior art keywords
makrolide
inflammatory effect
oxyimino
macrolides
endowed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60023647T
Other languages
English (en)
Other versions
DE60023647T2 (de
Inventor
Franco Pellacini
Daniela Botta
Stefano Romagnano
Ermanno Moriggi
Lorenzo Pradella
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zambon SpA
Original Assignee
Zambon SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zambon SpA filed Critical Zambon SpA
Publication of DE60023647D1 publication Critical patent/DE60023647D1/de
Application granted granted Critical
Publication of DE60023647T2 publication Critical patent/DE60023647T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Rheumatology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
DE60023647T 1999-01-15 2000-01-12 Makrolide mit entzündungshemmender wirkung Expired - Lifetime DE60023647T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ITMI990061 1999-01-15
IT1999MI000061A IT1306205B1 (it) 1999-01-15 1999-01-15 Macrolidi ad attivita' antiinfiammatoria.
PCT/EP2000/000163 WO2000042055A2 (en) 1999-01-15 2000-01-12 Macrolides with anti-inflammatory activity

Publications (2)

Publication Number Publication Date
DE60023647D1 true DE60023647D1 (de) 2005-12-08
DE60023647T2 DE60023647T2 (de) 2006-08-10

Family

ID=11381492

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60023647T Expired - Lifetime DE60023647T2 (de) 1999-01-15 2000-01-12 Makrolide mit entzündungshemmender wirkung

Country Status (19)

Country Link
US (1) US6455576B1 (de)
EP (1) EP1144427B1 (de)
JP (1) JP4568433B2 (de)
CN (1) CN1151165C (de)
AT (1) ATE308552T1 (de)
AU (1) AU769006B2 (de)
BR (1) BR0007514A (de)
CA (1) CA2368400C (de)
DE (1) DE60023647T2 (de)
ES (1) ES2251966T3 (de)
HU (1) HU229228B1 (de)
IL (2) IL144044A0 (de)
IT (1) IT1306205B1 (de)
MX (1) MXPA01007164A (de)
NO (1) NO318982B1 (de)
RU (1) RU2243230C2 (de)
SK (1) SK286772B6 (de)
WO (1) WO2000042055A2 (de)
ZA (1) ZA200105748B (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HRP20010018A2 (en) 2001-01-09 2002-12-31 Pliva D D Novel anti-inflammatory compounds
RU2330858C2 (ru) 2002-07-08 2008-08-10 Глаксомитклайн Истраживацки Центар Загреб Д.О.О. Новые соединения, составы и способы лечения воспалительных заболеваний и состояний
RS20050007A (en) * 2002-07-08 2007-09-21 Glaxo Smith Kline Istraživački Centar Zagreb D.O.O., Novel nonsteroidal anti- inflammatory substances, compositions and methods for their use
AU2003264917A1 (en) 2002-07-08 2004-01-23 Pliva - Istrazivacki Institut D.O.O. Hybrid molecules of macrolides with steroid/non-steroid anti-inflammatory, antineoplastic and antiviral active molecules
ITMI20021726A1 (it) * 2002-08-01 2004-02-02 Zambon Spa Macrolidi ad attivita' antiinfiammatoria.
TW200420573A (en) 2002-09-26 2004-10-16 Rib X Pharmaceuticals Inc Bifunctional heterocyclic compounds and methods of making and using same
ITMI20022292A1 (it) * 2002-10-29 2004-04-30 Zambon Spa 9a-azalidi ad attivita' antiinfiammatoria.
US7410952B2 (en) 2003-04-17 2008-08-12 Sandoz Ag Derivatives of azithromycin
HRP20030324A2 (en) 2003-04-24 2005-02-28 Pliva-Istra�iva�ki institut d.o.o. Compounds of antiinflammatory effect
ITMI20040124A1 (it) 2004-01-29 2004-04-29 Zambon Spa Macrolidi ad attivita' antiinfiammatoria
WO2006130128A2 (en) * 2004-02-18 2006-12-07 Chiron Corporation Methods of identifying anti-inflammatory macrolides
CN102816194A (zh) 2004-02-27 2012-12-12 瑞伯-X医药品有限公司 大环化合物以及其制作和使用方法
WO2006035301A2 (en) * 2004-09-27 2006-04-06 Ranbaxy Laboratories Limited Erythromycin a derivatives as antibacterial agents
CA2585711A1 (en) 2004-10-27 2006-05-04 Glaxosmithkline Istrazivacki Centar Zagreb D.O.O. Conjugates with anti-inflammatory activity
US20080249034A1 (en) * 2005-03-21 2008-10-09 Zambon S.P.A. Use of Macrolides for Treating Intestinal Inflammation
US7582611B2 (en) * 2005-05-24 2009-09-01 Pfizer Inc. Motilide compounds
US20110178287A1 (en) 2010-01-19 2011-07-21 Cerulean Pharma Inc. Cyclodextrin-based polymers for therapeutic delivery
RU2455309C2 (ru) * 2010-07-20 2012-07-10 Открытое Акционерное Общество "Татхимфармпрепараты" Способ получения аморфной формы рокситромицина
GB201608236D0 (en) 2016-05-11 2016-06-22 Fidelta D O O Seco macrolide compounds
AU2021241591A1 (en) 2020-03-24 2022-10-20 Michael W. BURNET Anti-infective and anti-viral compounds and compositions

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3928387A (en) * 1974-02-04 1975-12-23 Hoffmann La Roche Antibiotic 1745A/X and methods for the production thereof
IT1189285B (it) * 1982-05-28 1988-02-04 Nuovo Consor Sanitar Nazionale Sali dell'antibiotico eritromicina e del suo estere propionico con acidi ad attivita' terapeutica coadiuvante
EP0254534A3 (de) * 1986-07-24 1991-04-17 William S. Robinson Erythromycin-Derivate und Zusammensetzungen und ihre Verwendung, um Virusreplikation und Krankheiten zu Inhibieren
IT1276901B1 (it) * 1994-12-13 1997-11-03 Zambon Spa Derivati dell'eritromicina a 9-0-ossina dotati di attivita' antibiotica
KR19980701895A (ko) * 1995-03-08 1998-06-25 이라우치지마 가즈다카 면역관련병 처치제 및 그의 탐색 방법

Also Published As

Publication number Publication date
RU2243230C2 (ru) 2004-12-27
NO20013517D0 (no) 2001-07-16
CN1151165C (zh) 2004-05-26
HUP0105105A2 (hu) 2002-04-29
CA2368400A1 (en) 2000-07-20
IL144044A0 (en) 2002-04-21
WO2000042055A2 (en) 2000-07-20
CA2368400C (en) 2007-06-05
WO2000042055A3 (en) 2001-09-07
BR0007514A (pt) 2001-11-20
MXPA01007164A (es) 2002-03-27
US6455576B1 (en) 2002-09-24
IT1306205B1 (it) 2001-05-30
ATE308552T1 (de) 2005-11-15
EP1144427A3 (de) 2002-08-28
SK286772B6 (sk) 2009-05-07
HU229228B1 (en) 2013-09-30
IL144044A (en) 2006-12-31
NO318982B1 (no) 2005-05-30
ZA200105748B (en) 2002-10-14
HUP0105105A3 (en) 2003-05-28
SK9812001A3 (en) 2002-01-07
EP1144427A2 (de) 2001-10-17
ES2251966T3 (es) 2006-05-16
ITMI990061A1 (it) 2000-07-15
NO20013517L (no) 2001-07-16
JP4568433B2 (ja) 2010-10-27
DE60023647T2 (de) 2006-08-10
JP2002534531A (ja) 2002-10-15
EP1144427B1 (de) 2005-11-02
AU769006B2 (en) 2004-01-15
AU2663600A (en) 2000-08-01
CN1336932A (zh) 2002-02-20

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: ZAMBON S.P.A., BRESSO, IT