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ES8600783A1 - Procedimiento para la preparacion de la hormona polipeptidica factor de crecimiento de nervios de humano. - Google Patents

Procedimiento para la preparacion de la hormona polipeptidica factor de crecimiento de nervios de humano.

Info

Publication number
ES8600783A1
ES8600783A1 ES530202A ES530202A ES8600783A1 ES 8600783 A1 ES8600783 A1 ES 8600783A1 ES 530202 A ES530202 A ES 530202A ES 530202 A ES530202 A ES 530202A ES 8600783 A1 ES8600783 A1 ES 8600783A1
Authority
ES
Spain
Prior art keywords
growth factor
producing
nerve growth
host cells
cells transformed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES530202A
Other languages
English (en)
Other versions
ES530202A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genentech Inc
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23873671&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES8600783(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of ES8600783A1 publication Critical patent/ES8600783A1/es
Publication of ES530202A0 publication Critical patent/ES530202A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/48—Nerve growth factor [NGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Neurosurgery (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Neurology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE LA HORMONA POLIPEPTICA, FACTOR DE CRECIMIENTO DE NERVIOS DE HUMANO.COMPRENDE LAS SIGUIENTES OPERACIONES: PRIMERA, SE TRANSFORMA UNA CELULA HOSPEDANTE RECOMBINANTE CON UN VECTOR DE EXPRESION REPLICABLE, CAPAZ DE EXPRESAR UNA SECUENCIA DE ADN QUE CODIFICA BBBNGF DE HUMANO, ENLAZADO OPERANTEMENTE CON UNA SECUENCIA DE ADN CAPAZ DE EFECTUAR UNA EXPRESION DELA MISMA EN UNA CELULA HOSPEDANTE RECOMBINANTE; SEGUNDA, SE CULTIVA DICHA CELULA EN UN CULTIVO PREPARADO ADECUADAMENTE; Y POR ULTIMO, SE AISLA PERIODICAMENTE EL BBBNGF OBTENIDO EN DICHO CULTIVO.DE APLICACION EN LA PREPARACION DE COMPOSICIONES FARMACEUTICAS UTILIZADAS EN TERAPEUTICA.
ES530202A 1983-03-03 1984-03-01 Procedimiento para la preparacion de la hormona polipeptidica factor de crecimiento de nervios de humano. Granted ES530202A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US47196283A 1983-03-03 1983-03-03

Publications (2)

Publication Number Publication Date
ES8600783A1 true ES8600783A1 (es) 1985-11-01
ES530202A0 ES530202A0 (es) 1985-11-01

Family

ID=23873671

Family Applications (1)

Application Number Title Priority Date Filing Date
ES530202A Granted ES530202A0 (es) 1983-03-03 1984-03-01 Procedimiento para la preparacion de la hormona polipeptidica factor de crecimiento de nervios de humano.

Country Status (12)

Country Link
EP (1) EP0121338B2 (es)
JP (4) JPS6084299A (es)
KR (1) KR840008026A (es)
AT (1) ATE45382T1 (es)
AU (1) AU574350B2 (es)
CA (1) CA1220736A (es)
DE (1) DE3479321D1 (es)
DK (1) DK161152C (es)
ES (1) ES530202A0 (es)
IE (1) IE57013B1 (es)
NZ (1) NZ207337A (es)
ZA (1) ZA841597B (es)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE222602T1 (de) * 1985-09-12 2002-09-15 Scios Inc Rekombinante fibroblasten-wachstums-faktoren
JPH01102096A (ja) * 1987-10-15 1989-04-19 Sanwa Kagaku Kenkyusho Co Ltd モチリン様活性を有するポリペプチド、その発現用微生物及び該ポリペプチドの製法
JPH01211490A (ja) * 1988-02-19 1989-08-24 Tosoh Corp ヒト神経成長因子遺伝子セグメント
IT1219874B (it) * 1988-03-18 1990-05-24 Fidia Farmaceutici Utilizzazione del fattore di crescita nervoso umano e sue composizioni farmaceutiche
US5134121A (en) * 1988-03-28 1992-07-28 Regents Of The University Of California Nerve growth factor peptides
US5683894A (en) * 1988-04-29 1997-11-04 University Of California Recombinant nerve growth factor
JPH0771509B2 (ja) * 1988-07-12 1995-08-02 工業技術院長 ヒトβ−ＮＧＦの発現法
US5082774A (en) * 1988-08-30 1992-01-21 The General Hospital Corporation Recombinant human nerve growth factor
US5272063A (en) * 1988-11-22 1993-12-21 Syntex (U.S.A.) Inc. Process of making human nerve growth factor
US6709837B1 (en) 1989-03-10 2004-03-23 Takeda Chemical Industries, Inc. Polypeptide and production thereof
SE8901715L (sv) * 1989-05-12 1990-11-13 Lope Medicine Ab En plasmid dna-konstruktion innehaallande dna-sekvenser
IT1232157B (it) * 1989-07-20 1992-01-25 Fidia Farmaceutici Purificazione del fattore di crescita nervoso tramite cromatografia a scambio di subunita'
DK0414151T3 (da) * 1989-08-21 1995-05-22 Takeda Chemical Industries Ltd Humane nervevæskstfaktorproteiner og fremstilling deraf
US5656435A (en) * 1989-08-28 1997-08-12 Takeda Chemical Industries, Ltd. Antibodies to peptides having NGF-like activity, said antibodies having no substantial cross-reactivity with NGF, and use thereof
US6933276B1 (en) 1989-08-30 2005-08-23 Regeneron Pharmaceuticals, Inc. Methods of treating peripheral neuropathies using neurotrophin-3
US5180820A (en) * 1989-08-30 1993-01-19 Barde Yves Alain Brain-derived neurotrophic factor
GR1000980B (el) * 1989-08-30 1993-03-31 Max Planck Gesellschaft Νευροτροφινη-3,ενας νεος neυροτροφικος παραγοντας που σχετιζεται με τον παραγοντα αναπτυξης νευρων και τον νευροτροφικο παραγοντα που προερχεται απο τον εγκεφαλο.
IT1238348B (it) * 1989-11-16 1993-07-13 Processo per la preparazione di costrutti genetici per l'espressione del fattore di crescita nervoso in cellule eucariote.
JPH03244385A (ja) * 1990-02-21 1991-10-31 Hitachi Ltd ヒト神経成長因子の遺伝子工学的生産方法
IT1239271B (it) * 1990-02-27 1993-10-01 Fidia Spa Processo per l'espressione del fattore di crescita nervoso umano in cellule di artropoda frugiperda via infezione con baculovirus ricombinante
US5606031A (en) * 1990-04-06 1997-02-25 Lile; Jack Production and purification of biologically active recombinant neurotrophic protein in bacteria
US5986070A (en) * 1990-04-06 1999-11-16 Amgen Inc. Production of biologically active NGF proteins
US5235043A (en) * 1990-04-06 1993-08-10 Synergen, Inc. Production of biologically active, recombinant members of the ngf/bdnf family of neurotrophic proteins
US5389529A (en) * 1991-06-12 1995-02-14 Regeneron Pharmaceuticals, Inc. Modified lamβ signal sequence and processes for producing recombinant neurotrophins
PT100580A (pt) * 1991-06-12 1993-09-30 Regeneron Pharma Producao e recuperacao de neurotrofinas recombinantes
DE4139000A1 (de) * 1991-11-27 1993-06-03 Boehringer Mannheim Gmbh Verfahren zur gentechnologischen herstellung von biologisch aktivem ss-ngf
US6063757A (en) * 1995-11-29 2000-05-16 Urso; Richard G. Wound treatment method with nerve growth factor
EP0960937B1 (en) * 1996-09-11 2007-11-14 Dainippon Sumitomo Pharma Co., Ltd. Novel semaphorin gene: semaphorin y
DE69738074T2 (de) * 1996-11-15 2008-05-21 Genentech, Inc., South San Francisco Reinigung von neurotrophinen
AU5734298A (en) * 1997-02-06 1998-08-26 Aventis Pharmaceuticals Inc. Human nerve growth factor exon 1 and exon 3 promoters
US6197551B1 (en) * 1998-01-27 2001-03-06 Millennium Pharmaceuticals, Inc. Spoil-1 protein and nucleic acid molecules and uses therefor
ITRM20050045A1 (it) * 2005-02-02 2006-08-03 Consiglio Nazionale Ricerche Proteina isolata da eisenia foetida simile all'ngf umano e usi relativi.
US7378359B2 (en) 2005-09-27 2008-05-27 Eleazer Howell B Moldable fibrous construction incorporating non-woven layers
US7300691B2 (en) 2005-09-27 2007-11-27 Milliken & Company Moldable construction incorporating non-olefin bonding interface
US7294384B2 (en) 2005-09-27 2007-11-13 Milliken & Company Moldable construction incorporating bonding interface
US20080124513A1 (en) 2006-09-11 2008-05-29 Eleazer Howell B Moldable fabric with unidirectional tape yarns
JP6767688B2 (ja) 2015-05-20 2020-10-14 パナソニックＩｐマネジメント株式会社 室内空調システム
IT202000005542A1 (it) 2020-03-16 2021-09-16 Themis S R L Metodo cosmetico per il trattamento della pelle e per la ricrescita dei capelli

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4185095A (en) * 1977-11-23 1980-01-22 The Massachusetts General Hospital Nerve growth factor
ZA811368B (en) † 1980-03-24 1982-04-28 Genentech Inc Bacterial polypedtide expression employing tryptophan promoter-operator

Also Published As

Publication number Publication date
DK161152C (da) 1991-11-11
EP0121338B1 (en) 1989-08-09
EP0121338A1 (en) 1984-10-10
DK98884A (da) 1984-10-04
DK161152B (da) 1991-06-03
NZ207337A (en) 1987-11-27
AU574350B2 (en) 1988-07-07
DK98884D0 (da) 1984-02-24
EP0121338B2 (en) 1999-10-27
DE3479321D1 (en) 1989-09-14
JPH067169A (ja) 1994-01-18
ZA841597B (en) 1984-10-31
KR840008026A (ko) 1984-12-12
ATE45382T1 (de) 1989-08-15
JP2898494B2 (ja) 1999-06-02
JPH0536031B2 (es) 1993-05-28
JPH0690764A (ja) 1994-04-05
JPS6084299A (ja) 1985-05-13
JP2740417B2 (ja) 1998-04-15
IE57013B1 (en) 1992-03-11
IE840493L (en) 1984-09-03
CA1220736A (en) 1987-04-21
JPH05310792A (ja) 1993-11-22
AU2525284A (en) 1984-09-06
ES530202A0 (es) 1985-11-01

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20050712