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ES8502476A1 - Un procedimiento para obtener polipeptidos similares a la hormona del crecimiento de ganado bovino - Google Patents

Un procedimiento para obtener polipeptidos similares a la hormona del crecimiento de ganado bovino

Info

Publication number
ES8502476A1
ES8502476A1 ES524971A ES524971A ES8502476A1 ES 8502476 A1 ES8502476 A1 ES 8502476A1 ES 524971 A ES524971 A ES 524971A ES 524971 A ES524971 A ES 524971A ES 8502476 A1 ES8502476 A1 ES 8502476A1
Authority
ES
Spain
Prior art keywords
polypeptides
processes
high yield
growth hormone
bovine growth
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES524971A
Other languages
English (en)
Other versions
ES524971A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biogen NV
Original Assignee
Biogen NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogen NV filed Critical Biogen NV
Publication of ES524971A0 publication Critical patent/ES524971A0/es
Publication of ES8502476A1 publication Critical patent/ES8502476A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/61—Growth hormone [GH], i.e. somatotropin
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/168—Steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/12—Growth hormone, growth factor other than t-cell or b-cell growth factor, and growth hormone releasing factor; related peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/30—Signal or leader sequence

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Endocrinology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Polymers & Plastics (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Husbandry (AREA)
  • Food Science & Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Fodder In General (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Feed For Specific Animals (AREA)
  • Steroid Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

PROCEDIMIENTO PARA OBTENER POLIPEPTIDOS SIMILARES A LA HORMONA DE CRECIMIENTO DEL GANADO BOVINO.CONSISTE EN CULTIVAR UN HOSPEDANTE TRANSFORMADO CON UNA MOLECULA DE DNA RECOMBINANTE, QUE COMPRENDE UNA SECUENCIA DE DNA QUE CODIFICA DICHO POLIPEPTIDO Y QUE ESTA LIGADA OPERATIVAMENTE A UNA SECUENCIA DE CONTROL DE EXPRESION, ESTANDO DICHA SECUENCIA DE DNA PARTICULARIZADA POR UNA SUPRESION DE TERMINAL AMINO DE LA SECUENCIA DE DNA QUE CODIFICA LA HORMONA DE CRECIMIENTO BOVIDO MADURA. DICHA SECUENCIA DE DNA PERMITE LA PRODUCCION DEL POLIPEPTIDO CON UN RENDIMIENTO DE AL MENOS 100 VECES SUPERIOR AL DE LA SECUENCIA DE DNA QUE CODIFICA LA HORMONA DE CRECIMIENTO BOVINO MADURA.
ES524971A 1982-08-17 1983-08-16 Un procedimiento para obtener polipeptidos similares a la hormona del crecimiento de ganado bovino Expired ES8502476A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8223695 1982-08-17

Publications (2)

Publication Number Publication Date
ES524971A0 ES524971A0 (es) 1985-01-01
ES8502476A1 true ES8502476A1 (es) 1985-01-01

Family

ID=10532360

Family Applications (1)

Application Number Title Priority Date Filing Date
ES524971A Expired ES8502476A1 (es) 1982-08-17 1983-08-16 Un procedimiento para obtener polipeptidos similares a la hormona del crecimiento de ganado bovino

Country Status (12)

Country Link
US (1) US4693973A (es)
EP (1) EP0103395A3 (es)
JP (1) JPS5963197A (es)
AU (1) AU568597B2 (es)
CA (1) CA1224432A (es)
DD (1) DD212982A5 (es)
DK (1) DK375283A (es)
ES (1) ES8502476A1 (es)
NO (1) NO832948L (es)
NZ (1) NZ205212A (es)
PT (1) PT77206B (es)
ZA (1) ZA835880B (es)

Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ201918A (en) * 1981-09-18 1987-04-30 Genentech Inc N-terminal methionyl analogues of bovine growth hormone
US5254463A (en) * 1981-09-18 1993-10-19 Genentech, Inc. Method for expression of bovine growth hormone
EP0111814A3 (en) * 1982-12-16 1985-08-14 Mgi Pharma, Inc. The cloning and expression of nucleotide sequences encoding bovine growth hormone
BG49718A3 (en) * 1983-07-15 1992-01-15 Bio- Technology General Corp Method for preparing of polypeptid with superoxiddismutasne activitty
US4935370A (en) * 1983-12-23 1990-06-19 Pfizer Inc. Expression plasmids for improved production of heterologous protein in bacteria
EP0159123B1 (en) * 1984-03-06 1992-01-15 Eli Lilly And Company Vectors for expressing bovine growth hormone derivatives
US5489529A (en) * 1984-07-19 1996-02-06 De Boer; Herman A. DNA for expression of bovine growth hormone
US5037806A (en) * 1985-02-22 1991-08-06 Monsanto Company Biologically active method using somatotropins
US4861868A (en) * 1985-02-22 1989-08-29 Monsanto Company Production of proteins in procaryotes
US5141922A (en) * 1985-02-22 1992-08-25 Monsanto Company Biologically active proteins and a method for their use
US4670249A (en) * 1985-04-12 1987-06-02 International Minerals & Chemical Corp. Growth-promoting compositions
WO1987000204A2 (en) 1985-06-26 1987-01-15 The Upjohn Company Purification of somatotropin from transformed microorganisms
US4788144A (en) * 1985-06-28 1988-11-29 International Minerals & Chemical Corp. Fermentation process for the high level production of swine growth
US4786501A (en) * 1985-07-15 1988-11-22 International Minerals & Chemical Corp. Cylindrical implants for the controlled release of growth hormones
US4762784A (en) * 1985-07-15 1988-08-09 International Minerals & Chemical Corp. Fermemtation process for the high level production of bovine growth hormone
AU599922B2 (en) * 1985-09-10 1990-08-02 Natinco Nv Improving carcass quality
US5631227A (en) * 1985-09-18 1997-05-20 The Upjohn Company Somatotropin analogs
AU6469886A (en) * 1985-11-08 1987-05-14 Smithkline Beckman Corporation Mutant alpha-1-antitryosin and dna sequence therefor
US4892764A (en) * 1985-11-26 1990-01-09 Loctite Corporation Fiber/resin composites, and method of making the same
JPH0712318B2 (ja) * 1986-12-31 1995-02-15 株式会社ラッキー 合成遺伝子を使用したウシ成長ホルモンの製造方法
US5366876A (en) * 1986-12-31 1994-11-22 Lucky Ltd. Method for production of bovine growth hormone using a synthetic gene
EP0279616A3 (en) * 1987-02-17 1990-03-07 International Minerals And Chemical Corporation Swine growth promotion
US5240837A (en) * 1987-02-19 1993-08-31 The Upjohn Company CDNAS encoding somatotropin, expression vectors and hosts
WO1988007084A1 (en) * 1987-03-12 1988-09-22 Amgen Inc. Bovine growth hormone analogs
US5104806A (en) * 1987-03-12 1992-04-14 Amgen, Inc. Porcine growth hormone analogs encoding dna
US4888416A (en) * 1987-03-30 1989-12-19 International Minerals & Chemical Corp. Method for stabilizing somatotropins
US5192669A (en) * 1987-11-09 1993-03-09 Eli Lilly And Company Method to produce recombinant proteins using an expression vector comprising transcriptional and translational activating sequences
US5063158A (en) * 1987-11-09 1991-11-05 Eli Lilly And Company Recombinant DNA expression vector comprising both transcriptional and translational activating sequences
US5268284A (en) * 1988-03-11 1993-12-07 The Upjohn Company Ribosome binding site
EP0394409B1 (en) 1988-09-02 1997-06-11 The Rockefeller University Macrophage-derived inflammatory mediator (mip-2)
US5079230A (en) * 1988-09-12 1992-01-07 Pitman-Moore, Inc. Stable bioactive somatotropins
DK472189A (da) * 1988-09-29 1990-03-30 Bunge Australia Vaeksthormon
WO1990005185A1 (fr) * 1988-11-07 1990-05-17 L'universite De L'etat A Liege Hormone de croissance humaine modifiee
US5350836A (en) * 1989-10-12 1994-09-27 Ohio University Growth hormone antagonists
US6583115B1 (en) 1989-10-12 2003-06-24 Ohio University/Edison Biotechnology Institute Methods for treating acromegaly and giantism with growth hormone antagonists
US6787336B1 (en) 1989-10-12 2004-09-07 Ohio University/Edison Biotechnology Institute DNA encoding growth hormone antagonists
US5958879A (en) * 1989-10-12 1999-09-28 Ohio University/Edison Biotechnology Institute Growth hormone receptor antagonists and methods of reducing growth hormone activity in a mammal
US5266477A (en) * 1990-02-02 1993-11-30 Pitman-Moore, Inc. Monoclonal antibodies which differentiate between native and modified porcine somatotropins
JP3417558B2 (ja) * 1991-05-10 2003-06-16 ジェネンテク，インコーポレイテッド 配位子作用薬および拮抗薬の選択
GB2273931A (en) * 1992-09-28 1994-07-06 Unilever Plc Mutant polypeptides
EP0752853B1 (en) 1993-03-10 2005-09-21 Smithkline Beecham Corporation Human brain phosphodiesterase
SE9303068D0 (sv) * 1993-09-21 1993-09-21 Kabi Pharmacia Ab New use
US5767080A (en) * 1996-05-01 1998-06-16 Cargill, Incorporated Enhanced milk production in dairy cattle
ZA9711733B (en) 1996-12-31 1998-07-01 Monsanto Co Method for solubilization and naturation of somatotropins
US6087128A (en) * 1998-02-12 2000-07-11 Ndsu Research Foundation DNA encoding an avian E. coli iss
US20050256239A1 (en) * 2004-05-11 2005-11-17 Lee Chun D White polyolefin compositions having reduced die drool
CN107446943A (zh) * 2017-09-12 2017-12-08 浙江华军药业有限公司 重组牛生长激素的表达方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3265579A (en) * 1964-01-08 1966-08-09 Upjohn Co Process for purification of bovine growth hormone
US3308027A (en) * 1965-05-13 1967-03-07 Upjohn Co Bovine pituitary growth hormone process
US3664925A (en) * 1970-02-20 1972-05-23 Martin Sonenberg Clinically active bovine growth hormone fraction
US4056520A (en) * 1972-03-31 1977-11-01 Research Corporation Clinically active bovine growth hormone fraction
NZ187300A (en) * 1977-05-27 1982-08-17 Univ California Dna transfer vector and micro-organism modified to contain a nucleotide sequence equivalent to the gene of a higher organism
GR71912B (es) * 1978-08-11 1983-08-16 Univ California
US4443539A (en) * 1980-02-05 1984-04-17 The Upjohn Company Process for preparing bovine growth hormone
IL59690A (en) * 1980-03-24 1983-11-30 Yeda Res & Dev Production of bovine growth hormone by microorganisms and modified microorganisms adapted to produce it
IE52755B1 (en) * 1980-08-26 1988-02-17 Univ California Bovine pre-growth and growth hormone
DK188582A (da) * 1981-04-29 1982-10-30 Biogen Nv Bacillus-kloningsvektorer rekombinations-dna-molekyler bacillus-vaerter transformeret dermed samt fremgangsmaader til ekspressionaf fremmede dna-sekvenser og fremstilling af polypeptideer som er kodede dermed
JPS58996A (ja) * 1981-06-01 1983-01-06 ザ・ボ−ド・オブ・トラステイ−ズ・ミシガンステ−トユニバ−シテイ− 細菌中での牛成長ホルモン遺伝子のクロ−ン化
NZ201918A (en) * 1981-09-18 1987-04-30 Genentech Inc N-terminal methionyl analogues of bovine growth hormone
US4371462A (en) * 1982-01-21 1983-02-01 Genex Corporation Method for purification of anterior pituitary hormones

Also Published As

Publication number Publication date
ZA835880B (en) 1984-04-25
US4693973A (en) 1987-09-15
DK375283D0 (da) 1983-08-16
NZ205212A (en) 1987-03-31
ES524971A0 (es) 1985-01-01
CA1224432A (en) 1987-07-21
AU568597B2 (en) 1988-01-07
JPS5963197A (ja) 1984-04-10
PT77206B (en) 1986-06-02
PT77206A (en) 1983-09-01
DK375283A (da) 1984-02-18
AU1802183A (en) 1984-02-23
DD212982A5 (de) 1984-08-29
EP0103395A3 (en) 1985-05-22
NO832948L (no) 1984-02-20
EP0103395A2 (en) 1984-03-21

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