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ES2179829T3 - Preparacion de hidrogel de liberacion prolongada. - Google Patents

Preparacion de hidrogel de liberacion prolongada.

Info

Publication number
ES2179829T3
ES2179829T3 ES93919648T ES93919648T ES2179829T3 ES 2179829 T3 ES2179829 T3 ES 2179829T3 ES 93919648 T ES93919648 T ES 93919648T ES 93919648 T ES93919648 T ES 93919648T ES 2179829 T3 ES2179829 T3 ES 2179829T3
Authority
ES
Spain
Prior art keywords
preparation
drug
release
hydrogel
colon
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93919648T
Other languages
English (en)
Inventor
Kazuhiro Sako
Hiroshi Nakashima
Toyohiro Sawada
Akira Okada
Muneo Fukui
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yamanouchi Pharmaceutical Co Ltd
Original Assignee
Yamanouchi Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26490061&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2179829(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Yamanouchi Pharmaceutical Co Ltd filed Critical Yamanouchi Pharmaceutical Co Ltd
Application granted granted Critical
Publication of ES2179829T3 publication Critical patent/ES2179829T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • A61K9/2018Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2031Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

UNA PREPARACION DE HIDROGEL DE REPOSICION SOSTENIDA COMPRENDE AL MENOS UN MEDICAMENTO, UN ADITIVO PARA HACER QUE EL AGUA PENETRE EN LA PREPARACION Y UNA SUSTANCIA MACROMOLECULAR QUE FORMA EL HIDROGEL. ELLO CONSERVA CASI TOTALMENTE EL GEL CUANDO PERMANECE EN LAS PARTES SUPERIORES DE LA ZONA DIGESTIVA, EJ. EL ESTOMAGO E INTESTINO DELGADO, Y PUEDE REPONER EL MEDICAMENTO EN LA PARTE INFERIOR DEL MISMO, EJ. EL COLON. LA PREPARACION POSIBILITA QUE EL MEDICAMENTO SE DISUELVA Y ABSORBA BIEN INCLUSO EN EL COLON, ASEGURANDO ADEMAS UN EFECTO ESTABLE DE REPOSICION SOSTENIDA.
ES93919648T 1992-09-18 1993-09-10 Preparacion de hidrogel de liberacion prolongada. Expired - Lifetime ES2179829T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP27497992 1992-09-18
JP16526393 1993-06-08

Publications (1)

Publication Number Publication Date
ES2179829T3 true ES2179829T3 (es) 2003-02-01

Family

ID=26490061

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93919648T Expired - Lifetime ES2179829T3 (es) 1992-09-18 1993-09-10 Preparacion de hidrogel de liberacion prolongada.

Country Status (23)

Country Link
US (3) US6436441B1 (es)
EP (1) EP0661045B1 (es)
JP (1) JP3140465B2 (es)
KR (1) KR100355130B1 (es)
CN (1) CN1048397C (es)
AT (1) ATE219933T1 (es)
AU (1) AU682827B2 (es)
BG (1) BG61861B1 (es)
CA (1) CA2144077C (es)
CZ (1) CZ291495B6 (es)
DE (1) DE69332081T2 (es)
DK (1) DK0661045T3 (es)
ES (1) ES2179829T3 (es)
FI (1) FI115697B (es)
HU (1) HU226456B1 (es)
NO (1) NO312811B1 (es)
NZ (1) NZ255579A (es)
PL (1) PL175026B1 (es)
PT (1) PT661045E (es)
RO (1) RO112991B1 (es)
RU (1) RU2121830C1 (es)
SK (1) SK281042B6 (es)
WO (1) WO1994006414A1 (es)

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* Cited by examiner, † Cited by third party
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