EP0749290A1 - Platzhalter zum anordnen in einer körperröhre - Google Patents
Platzhalter zum anordnen in einer körperröhreInfo
- Publication number
- EP0749290A1 EP0749290A1 EP95942643A EP95942643A EP0749290A1 EP 0749290 A1 EP0749290 A1 EP 0749290A1 EP 95942643 A EP95942643 A EP 95942643A EP 95942643 A EP95942643 A EP 95942643A EP 0749290 A1 EP0749290 A1 EP 0749290A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- placeholder
- wires
- jacket
- placeholder according
- wire
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
- A61F2/06—Blood vessels
- A61F2/07—Stent-grafts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/02—Inorganic materials
- A61L31/022—Metals or alloys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/04—Macromolecular materials
- A61L31/06—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
- A61F2/89—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure the wire-like elements comprising two or more adjacent rings flexibly connected by separate members
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
- A61F2/06—Blood vessels
- A61F2/07—Stent-grafts
- A61F2002/072—Encapsulated stents, e.g. wire or whole stent embedded in lining
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2210/0014—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof using shape memory or superelastic materials, e.g. nitinol
- A61F2210/0019—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof using shape memory or superelastic materials, e.g. nitinol operated at only one temperature whilst inside or touching the human body, e.g. constrained in a non-operative shape during surgery, another temperature only occurring before the operation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2220/00—Fixations or connections for prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2220/0025—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
- A61F2220/0075—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements sutured, ligatured or stitched, retained or tied with a rope, string, thread, wire or cable
Definitions
- the invention relates to a placeholder (stent) for arrangement in a body tube according to the features in the preamble of claim 1.
- a placeholder for arrangement in a body tube according to the features in the preamble of claim 1.
- Such placeholders are used in the treatment of stenoses.
- Stenosis is a congenital or acquired narrowing in a tube. It can affect hollow organs, such as the trachea, esophagus, stomach and intestines, or blood vessels and can be caused as a result of disease processes through the formation of tumors, inflammation with connective tissue growths or shrinking scars, through thrombosis or arteriosclerotic processes as well as through burns.
- a stenosis causes congestion or even occlusion of the affected body tube.
- stents to widen or keep open stenoses, be it in blood vessels or in other hollow organs. As an internal support, the stents keep the vessel open and thus act as a placeholder.
- Placeholders for keeping stenoses open are known in various embodiments. They are made of metal and / or plastic material. They usually consist of a network of metal wires, which expand themselves due to their inherent tension. However, there are also placeholders which only have to be expanded into their expanded position at their place of use by means of a suitable device, for example a balloon catheter. Due to DE-OS 42 19 949 or DE-OS 43 01 181, placeholders made of so-called memory metal also belong to the prior art. These placeholders have a small radial diameter at a low temperature. In this state, they are placed in the stenosis. They then expand radially when a limit temperature which is below body temperature is exceeded, so that they can keep a stenosis open in this way.
- the above-mentioned embodiments have the disadvantage that the placeholders, when radial pressure is exerted on them, such as, for example, by compression before insertion, move in the axial direction lengthen and shorten accordingly when expanding.
- a change in length can also be observed with natural stresses on the placeholder, such as during a coughing process. This can lead to problems because it can lead to relative movements between the placeholder and the wall of the body tube in which the placeholder is placed. As a result, irritation of the tube wall or the surrounding tissue occurs. Furthermore, the relative movement can also cause the placeholder to slip.
- the invention has for its object to provide a placeholder with a simple structure in which in particular the risk of growing through is avoided and which ensures gentle placement in the body tube.
- Each wire has at least three legs, the middle leg with the two adjacent legs each forming an acute angle.
- the individual wires of the scaffolding therefore have a fir tree-like configuration.
- One leg merges into an opposing leg, including an acute angle. This leg then adjoins the next leg at an acute angle.
- the support structure formed from a plurality of staggered wires is embedded in a jacket which is made of a plastic which is elastic at body temperature.
- the jacket prevents tissue cells from growing through the scaffold.
- an entire wire can consist of only three legs. Because the middle leg with the two adjacent legs each encloses an acute angle, the middle leg can be shorter than the two adjacent outer legs.
- This geometric shape of the wires ensures that the placeholder is stable in length. Even if the placeholder is compressed, its length does not change. This is particularly important when planning the treatment of a stenosis, since the placeholder can now be precisely adjusted to its required length.
- the placeholder Even if pressure is exerted on a wire perpendicular to the longitudinal axis of the leg, the placeholder remains stable in length. In this case, the wire bends towards the middle. The adjacent wires would then move relatively apart. However, this is prevented by embedding the support structure in the elastic jacket. If a length stability of the placeholder is not necessary or not wanted, the placeholder can also be designed according to the features of claim 3 so that the angle between two legs is greater than or equal to 45 ° and less than or equal to 90 °.
- Such a placeholder has a uniform restoring force on the circumference. It is uncomplicated in its structure and can be easily manufactured accordingly.
- the placeholder also has advantages with regard to the assembly, which must be matched to the respective stenosis, since the placeholder can simply be cut to the required length.
- the circumferential restoring force of the placeholder is supported by the features of claim 4. Thereafter, two wires that are adjacent to one another on the circumferential side of the sheath mesh with one another in a tooth-like manner. This means that the tips formed by two legs of a wire overlap each other by a certain amount, in such a way that the tips of one wire engage in the bulges of the adjacent wire. However, the wires do not touch. In this way, an effective interaction of the support structure with the jacket is ensured. If pressure is exerted on the placeholder, the legs move away from each other, which creates a tensile stress in the jacket which causes the resetting. This transforms the tensile force in the jacket into a compressive force.
- the respective adjacent legs are connected to one another via rounded longitudinal sections. So sharp edges are avoided, which u. U. damage to the jacket could lead.
- a wire can then be produced in a simple manner by bending over rounded forming tools.
- projections are provided on the jacket distributed over the circumference. These can be arranged evenly or irregularly.
- the abutments can be produced in that two adjacent legs do not run plane-parallel to the outer circumference of the placeholder, but are instead tilted or twisted relative to the outside.
- the placeholder is given a non-smooth, protruded surface.
- this configuration is gentler for the affected organ or vessel walls and also the mucous membranes than a circular anchoring.
- the surface then has an irregular corrugated structure. This prevents blood vessels from being pinched off or pressed on the circumference of the placeholder. As a result, a better blood supply in the external blood vessels is guaranteed.
- the abutment structure of the wire can be provided over its entire length. However, it is also conceivable to form the projections only on a few legs at a time. Another possibility is to create a placeholder with projections if the ends of the wires of the supporting structure protrude beyond the jacket and / or are still formed. In this way, projections can be formed in the form of claws at the ends.
- the wires are made of metal. Any metal that meets the requirements from a medical point of view can be used here.
- the wires are made of steel and the sheath is made of an elastomer, as provided for in claim 9. It must be stainless steel. This is inexpensive and easy to use.
- the self-expanding effect of the placeholder is promoted by the inherent tension in the steel. Silicone is the preferred material for the jacket.
- other types of synthetic rubber which have the medical requirements, in particular with regard to tissue compatibility and the absence of allergens.
- a suitable tool is required to insert the placeholder.
- the tool holds the placeholder together during the insertion process.
- the placeholder is released by the tool for placement and expands into its expanded position solely by the inherent tension in the material.
- the wires can also be made of a memory metal, as provided for in claim 10.
- This is a shape-memory alloy.
- Such alloys are used mostly formed from a combination of the two metals nickel and titanium (nitinol).
- This material has a compressed structure at a low temperature. However, it expands when a limit temperature is exceeded.
- the respectively desired limit conditions can be set by a corresponding choice of the alloy components.
- An elastomer with a low tensile force such as latex, is used as the material for the jacket.
- the sheath must allow the expansion of the MemoryMetall wires and, after the expansion, ensure such elasticity that collapse, i. H. a collapse of the overall structure is prevented.
- the elastomer consequently ensures sufficient stabilization of the wires.
- An advantageous embodiment of the invention consists in the feature of claim 11.
- the jacket then consists of a memory elastomer.
- This is a temperature-dependent elastomer (Shape Memory Polyurethane), which is hard and small when cold. As a result, the placeholder can be inserted easily. Only at body temperature or slightly below does the placeholder expand.
- the combination of a memory elastomer as a jacket with wires made of a memory metal, as provided in claim 12, is considered to be particularly advantageous.
- the wires made of memory metal or nitinol are soft at room temperature.
- a shape memory polyurethane is hard on the other hand. The combination results in a tube Chen, which is thin and hard at room temperature.
- the shape memory polyurethane becomes soft and flexible at body temperature, while the Nitinol support unit unfolds. This creates a thick, hard, but elastic placeholder.
- An insertion tool is not required for such a placeholder because the placeholder is hard and small when cold. It can therefore be easily introduced. This also contributes to the fact that Nitinol is deformable in the cold state, i. H. is plastically soft.
- the placeholder is produced in such a way that the memory metal, in a state in which it is still soft and malleable, is brought together with the memory elastomer when it is already soft.
- the support structure is therefore cast into the elastomer in a narrow, small condition.
- the manufacturing process is carried out in a temperature range in which the two materials have not yet changed their physical state.
- the wires forming the supporting structure are made of plastic. Suitable plastics are available for this, which ensure the desired stability and resilience for the placeholder.
- the wires made of plastic can also be embedded in a jacket which consists of a memory elastomer (claim 14).
- the wires have predetermined bending points.
- a placeholder can be provided which is characterized by its length stability. For example If an external force is applied vertically to the tip formed by two legs, this leads to a deflection of the legs. However, the other ends of a leg remain in a stable position, ie they are not seen in the axial direction of the placeholder. The placeholder thus remains constant in its entire length.
- the legs are reset by the elastic properties of the wire, which are supported by the elastic properties of the sheath.
- the predetermined bending points according to the invention can be produced, for example, by thinning or indenting the wire at suitable points. are provided. However, it is also possible to generate the predetermined bending points by combining two or more different materials in the wires.
- Figure 1 in side view of a wire with three legs and the representation of motion sequences
- FIG. 2 shows a wire according to the invention with rounded break points
- FIG. 3a-g seven different types of wire
- Figure 4 shows a placeholder in a three-dimensional representation
- Fig. 5a a developed section of a
- FIG. 5b shows the developed section of a further alternative of a placeholder
- Figure 6 is a vertical side view
- Figure 7 shows a detail of a placeholder in horizontal cross section
- Figure 8a two legs of a wire with predetermined bending points;
- Figure 8b shows the representation of Figure 8a in a bent position
- Figure 9 shows a section of a wire that is made of two different materials.
- three legs 2, 3, 4 of a wire 1 are illustrated.
- the middle leg 3 includes with the two adjacent legs 2 and 4 each an acute angle a, ⁇ of 35 c .
- the break point B moves downward and inward in the image plane in a rotational movement (identified by PFl).
- the inner break point C moves in an opposite direction (marked PF2) outwards or upwards. Due to the overlapping movements, they lift each other on.
- the total length X of wire 1 consequently remains constant.
- the end points A and D can move radially in the direction PF3 and PF4 without experiencing an axial displacement.
- a placeholder whose support structure is constructed from the zigzag-shaped wires remains stable in its entire length, even when it is pressed together.
- FIG. 2 shows a section of a wire 5, the legs 6, 7, 8 of which are connected to one another via rounded longitudinal sections 9, 10, 11.
- FIGS. 3a to 3g Different configurations of wires 12 to 18 are shown in FIGS. 3a to 3g. All wires 12 to 18 have in common is that the legs each enclose acute angles.
- angles ⁇ ', ⁇ ' 'of the wires 12, 13, 14 and 17 are each less than 45 °.
- the angles ⁇ ', ⁇ ' 'of the wires 15 and 16, however, are larger than 45 °.
- Figure 3g shows one.
- Wire 18 with legs 19-22 in which the angle u between the legs 19 and 20 or 21 and 22 in each case is greater than 45 °, the angle ⁇ between the legs 20 and 21 is less than 45 °.
- a placeholder 23 with a hollow cylindrical jacket 24 can be seen from FIG.
- a support structure 25 is embedded in the jacket 24.
- the support structure 25 is formed by the wires 26, which extend parallel to the longitudinal axis L of the jacket 24 and are each offset from one another.
- the jacket 24 is made of an elastomer.
- a memory elastomer is preferably used here.
- the wires 26 are made of metal, a memory metal advantageously being used here.
- FIG. 5 a shows a section from a placeholder in which 28 wires 29 with rounded length sections 30 are embedded in the jacket.
- the wires 29 also interlock like a tooth.
- a toothing is also implemented in the configuration according to FIG. 5b.
- the individual legs 32, 33, 34 merge into one another with pointed edges 35.
- FIGS. 6 and 7 show a wire 36 which forms projections 39 in the sheath 37 distributed over its circumference 38.
- the bends 40 between the individual legs 41, 42 of the wire 36 are twisted outward over the circumference 38 such that the projections 39 are formed out of the jacket 37.
- the projections 39 ensure that a placeholder is held securely after it has been installed in a body tube.
- FIGS. 8a and 8b show a section of a wire 43, in the legs 44, 45 of which predetermined bending points 46, 47 are integrated. If the wire 43 is loaded from the direction marked PF5, the tip 48 is displaced between the two legs 44, 45 to the right in the image plane with deformation of the predetermined bending points 46, 47, without the leg regions 49, 50 being displaced. As a result, the wire 43 remains constant in its entire length.
- FIG. 9 A further embodiment of a wire 51 with predetermined bending points 52, 53 is shown in FIG. 9.
- the wire 51 has sections 54, 55 which are made of different materials. By combining the different materials with different material parameters, zones are realized in the wire 51, on which the wire 51 preferably bends under load.
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- Veterinary Medicine (AREA)
- Vascular Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Surgery (AREA)
- Cardiology (AREA)
- Epidemiology (AREA)
- Transplantation (AREA)
- Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Pulmonology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Prostheses (AREA)
- Media Introduction/Drainage Providing Device (AREA)
Abstract
Description
Claims
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4446036 | 1994-12-23 | ||
DE4446036A DE4446036C2 (de) | 1994-12-23 | 1994-12-23 | Platzhalter zum Anordnen in einer Körperröhre |
PCT/DE1995/001849 WO1996019952A2 (de) | 1994-12-23 | 1995-12-19 | Platzhalter zum anordnen in einer körperröhre |
Publications (2)
Publication Number | Publication Date |
---|---|
EP0749290A1 true EP0749290A1 (de) | 1996-12-27 |
EP0749290B1 EP0749290B1 (de) | 2003-02-19 |
Family
ID=6536756
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP95942643A Expired - Lifetime EP0749290B1 (de) | 1994-12-23 | 1995-12-19 | Platzhalter zum anordnen in einer körperröhre |
Country Status (5)
Country | Link |
---|---|
US (1) | US5814063A (de) |
EP (1) | EP0749290B1 (de) |
JP (1) | JP3734505B2 (de) |
DE (2) | DE4446036C2 (de) |
WO (1) | WO1996019952A2 (de) |
Families Citing this family (68)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6814747B2 (en) | 1995-09-08 | 2004-11-09 | Anthony Walter Anson | Surgical graft/stent system |
US6451044B1 (en) | 1996-09-20 | 2002-09-17 | Board Of Regents, The University Of Texas System | Method and apparatus for heating inflammed tissue |
US6432127B1 (en) | 1996-10-11 | 2002-08-13 | Transvascular, Inc. | Devices for forming and/or maintaining connections between adjacent anatomical conduits |
US6330884B1 (en) | 1997-11-14 | 2001-12-18 | Transvascular, Inc. | Deformable scaffolding multicellular stent |
US7520890B2 (en) * | 1998-01-26 | 2009-04-21 | Phillips Peter W | Reinforced graft and method of deployment |
ES2252926T3 (es) * | 1998-01-26 | 2006-05-16 | Anson Medical Limited | Injerto reforzado. |
US20050154446A1 (en) * | 1998-01-26 | 2005-07-14 | Peter Phillips | Reinforced graft |
US6533807B2 (en) * | 1998-02-05 | 2003-03-18 | Medtronic, Inc. | Radially-expandable stent and delivery system |
US7887578B2 (en) | 1998-09-05 | 2011-02-15 | Abbott Laboratories Vascular Enterprises Limited | Stent having an expandable web structure |
US7815763B2 (en) | 2001-09-28 | 2010-10-19 | Abbott Laboratories Vascular Enterprises Limited | Porous membranes for medical implants and methods of manufacture |
DE19840645A1 (de) | 1998-09-05 | 2000-03-09 | Jomed Implantate Gmbh | Stent |
US20020019660A1 (en) * | 1998-09-05 | 2002-02-14 | Marc Gianotti | Methods and apparatus for a curved stent |
US6682554B2 (en) | 1998-09-05 | 2004-01-27 | Jomed Gmbh | Methods and apparatus for a stent having an expandable web structure |
US6755856B2 (en) | 1998-09-05 | 2004-06-29 | Abbott Laboratories Vascular Enterprises Limited | Methods and apparatus for stenting comprising enhanced embolic protection, coupled with improved protection against restenosis and thrombus formation |
US6475234B1 (en) * | 1998-10-26 | 2002-11-05 | Medinol, Ltd. | Balloon expandable covered stents |
US6214042B1 (en) * | 1998-11-10 | 2001-04-10 | Precision Vascular Systems, Inc. | Micro-machined stent for vessels, body ducts and the like |
US6334868B1 (en) | 1999-10-08 | 2002-01-01 | Advanced Cardiovascular Systems, Inc. | Stent cover |
US6537310B1 (en) * | 1999-11-19 | 2003-03-25 | Advanced Bio Prosthetic Surfaces, Ltd. | Endoluminal implantable devices and method of making same |
KR100319663B1 (ko) * | 1999-12-07 | 2002-01-05 | 이길환 | 스텐트 |
US6423090B1 (en) | 2000-02-11 | 2002-07-23 | Advanced Cardiovascular Systems, Inc. | Stent pattern with staged expansion |
US6805704B1 (en) | 2000-06-26 | 2004-10-19 | C. R. Bard, Inc. | Intraluminal stents |
US6641607B1 (en) | 2000-12-29 | 2003-11-04 | Advanced Cardiovascular Systems, Inc. | Double tube stent |
DE10118944B4 (de) | 2001-04-18 | 2013-01-31 | Merit Medical Systems, Inc. | Entfernbare, im wesentlichen zylindrische Implantate |
US7547321B2 (en) | 2001-07-26 | 2009-06-16 | Alveolus Inc. | Removable stent and method of using the same |
US6652508B2 (en) | 2001-11-09 | 2003-11-25 | Scimed Life Systems, Inc. | Intravascular microcatheter having hypotube proximal shaft with transition |
US7670302B2 (en) * | 2001-12-18 | 2010-03-02 | Boston Scientific Scimed, Inc. | Super elastic guidewire with shape retention tip |
US7488338B2 (en) | 2001-12-27 | 2009-02-10 | Boston Scientific Scimed, Inc. | Catheter having an improved torque transmitting shaft |
US20040093056A1 (en) | 2002-10-26 | 2004-05-13 | Johnson Lianw M. | Medical appliance delivery apparatus and method of use |
US7875068B2 (en) | 2002-11-05 | 2011-01-25 | Merit Medical Systems, Inc. | Removable biliary stent |
US7527644B2 (en) | 2002-11-05 | 2009-05-05 | Alveolus Inc. | Stent with geometry determinated functionality and method of making the same |
US7637942B2 (en) | 2002-11-05 | 2009-12-29 | Merit Medical Systems, Inc. | Coated stent with geometry determinated functionality and method of making the same |
US7959671B2 (en) | 2002-11-05 | 2011-06-14 | Merit Medical Systems, Inc. | Differential covering and coating methods |
US8105373B2 (en) * | 2002-12-16 | 2012-01-31 | Boston Scientific Scimed, Inc. | Flexible stent with improved axial strength |
US7637934B2 (en) | 2003-03-31 | 2009-12-29 | Merit Medical Systems, Inc. | Medical appliance optical delivery and deployment apparatus and method |
US7604660B2 (en) | 2003-05-01 | 2009-10-20 | Merit Medical Systems, Inc. | Bifurcated medical appliance delivery apparatus and method |
DE10336965B4 (de) * | 2003-08-12 | 2010-06-17 | B. Braun Melsungen Ag | Radial aufweitbares, hohlzylindrisches Implantat |
US20050131515A1 (en) * | 2003-12-16 | 2005-06-16 | Cully Edward H. | Removable stent-graft |
US7887579B2 (en) | 2004-09-29 | 2011-02-15 | Merit Medical Systems, Inc. | Active stent |
US7731654B2 (en) | 2005-05-13 | 2010-06-08 | Merit Medical Systems, Inc. | Delivery device with viewing window and associated method |
US20070233221A1 (en) * | 2006-03-31 | 2007-10-04 | The Board Of Regents, The University Of Texas System | Esophageal dilation and stent delivery system and method of use |
US10004584B2 (en) | 2006-07-10 | 2018-06-26 | First Quality Hygienic, Inc. | Resilient intravaginal device |
US8613698B2 (en) | 2006-07-10 | 2013-12-24 | Mcneil-Ppc, Inc. | Resilient device |
US10219884B2 (en) | 2006-07-10 | 2019-03-05 | First Quality Hygienic, Inc. | Resilient device |
WO2008008794A2 (en) | 2006-07-10 | 2008-01-17 | Mc Neil-Ppc, Inc. | Resilient device |
US7717892B2 (en) | 2006-07-10 | 2010-05-18 | Mcneil-Ppc, Inc. | Method of treating urinary incontinence |
CA2665868C (en) * | 2006-10-16 | 2013-08-06 | Wilson-Cook Medical Inc. | Nonexpandable stent |
US9622888B2 (en) | 2006-11-16 | 2017-04-18 | W. L. Gore & Associates, Inc. | Stent having flexibly connected adjacent stent elements |
US8128679B2 (en) | 2007-05-23 | 2012-03-06 | Abbott Laboratories Vascular Enterprises Limited | Flexible stent with torque-absorbing connectors |
US8016874B2 (en) | 2007-05-23 | 2011-09-13 | Abbott Laboratories Vascular Enterprises Limited | Flexible stent with elevated scaffolding properties |
DE102007032338B4 (de) * | 2007-07-11 | 2009-08-20 | Acandis Gmbh & Co. Kg | Implantat und Verfahren zur Herstellung eines derartigen Implantats |
US7850726B2 (en) | 2007-12-20 | 2010-12-14 | Abbott Laboratories Vascular Enterprises Limited | Endoprosthesis having struts linked by foot extensions |
US8337544B2 (en) | 2007-12-20 | 2012-12-25 | Abbott Laboratories Vascular Enterprises Limited | Endoprosthesis having flexible connectors |
US8920488B2 (en) | 2007-12-20 | 2014-12-30 | Abbott Laboratories Vascular Enterprises Limited | Endoprosthesis having a stable architecture |
US8926688B2 (en) | 2008-01-11 | 2015-01-06 | W. L. Gore & Assoc. Inc. | Stent having adjacent elements connected by flexible webs |
US9375307B2 (en) * | 2008-09-17 | 2016-06-28 | Cook Medical Technologies Llc | Graft fabric crimping pattern |
DE102010026830A1 (de) * | 2010-07-12 | 2012-01-12 | Acandis Gmbh & Co. Kg | Medizinische Vorrichtung und Verfahren zur Herstellung eines derartigen Vorrichtung |
EP2658484A1 (de) | 2010-12-30 | 2013-11-06 | Boston Scientific Scimed, Inc. | Stentausführungen mit mehrstufiger öffnung |
WO2012119037A1 (en) | 2011-03-03 | 2012-09-07 | Boston Scientific Scimed, Inc. | Stent with reduced profile |
WO2012118526A1 (en) | 2011-03-03 | 2012-09-07 | Boston Scientific Scimed, Inc. | Low strain high strength stent |
WO2014178198A1 (ja) * | 2013-05-02 | 2014-11-06 | テルモ株式会社 | 血栓除去デバイス |
CN105705118B (zh) | 2013-09-12 | 2018-03-30 | 波士顿科学国际有限公司 | 具有防移位连接器的支架 |
EP3119354B1 (de) | 2014-03-18 | 2018-06-06 | Boston Scientific Scimed, Inc. | Stententwurf für reduzierte granulierung und entzündung |
WO2016054536A1 (en) | 2014-10-02 | 2016-04-07 | Boston Scientific Scimed, Inc. | Controlled ingrowth feature for antimigration |
KR101949065B1 (ko) | 2014-10-22 | 2019-02-15 | 보스톤 싸이엔티픽 싸이메드 인코포레이티드 | 가요성 힌지를 구비한 스텐트 |
WO2016073597A1 (en) | 2014-11-06 | 2016-05-12 | Boston Scientific Scimed, Inc. | Tracheal stent |
US10299948B2 (en) | 2014-11-26 | 2019-05-28 | W. L. Gore & Associates, Inc. | Balloon expandable endoprosthesis |
US10568752B2 (en) | 2016-05-25 | 2020-02-25 | W. L. Gore & Associates, Inc. | Controlled endoprosthesis balloon expansion |
CN114938628A (zh) | 2020-01-13 | 2022-08-23 | 波士顿科学国际有限公司 | 防移位支架 |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4604762A (en) * | 1981-02-13 | 1986-08-12 | Thoratec Laboratories Corporation | Arterial graft prosthesis |
US4503569A (en) * | 1983-03-03 | 1985-03-12 | Dotter Charles T | Transluminally placed expandable graft prosthesis |
JP2561853B2 (ja) * | 1988-01-28 | 1996-12-11 | 株式会社ジェイ・エム・エス | 形状記憶性を有する成形体及びその使用方法 |
DE4102550A1 (de) * | 1990-02-02 | 1991-08-08 | Stephan Prof Dr Bockenheimer | Stent zur abdichtung von gefaessen bei arteriovenoesen fisteln oder gefaessbandaussackungen im arteriellen bereich (aneurysmata) |
JPH067843B2 (ja) * | 1990-02-15 | 1994-02-02 | 寛治 井上 | フレーム付き人工血管 |
US5064435A (en) * | 1990-06-28 | 1991-11-12 | Schneider (Usa) Inc. | Self-expanding prosthesis having stable axial length |
US5258020A (en) * | 1990-09-14 | 1993-11-02 | Michael Froix | Method of using expandable polymeric stent with memory |
DK0480667T3 (da) * | 1990-10-09 | 1996-06-10 | Cook Inc | Perkutan stentkonstruktion |
DE9014230U1 (de) * | 1990-10-13 | 1991-11-21 | Angiomed AG, 7500 Karlsruhe | Vorrichtung zum Aufweiten einer Stenose in einer Körperröhre |
US5330500A (en) * | 1990-10-18 | 1994-07-19 | Song Ho Y | Self-expanding endovascular stent with silicone coating |
US5250070A (en) * | 1991-05-28 | 1993-10-05 | Parodi Juan C | Less traumatic angioplasty balloon for arterial dilatation |
US5314472A (en) * | 1991-10-01 | 1994-05-24 | Cook Incorporated | Vascular stent |
US5167614A (en) * | 1991-10-29 | 1992-12-01 | Medical Engineering Corporation | Prostatic stent |
US5683448A (en) * | 1992-02-21 | 1997-11-04 | Boston Scientific Technology, Inc. | Intraluminal stent and graft |
DE4219949A1 (de) * | 1992-06-18 | 1993-12-23 | Angiomed Ag | Stent zum Offenhalten von Stenosen in Gefässen oder dergleichen |
DE4301181C2 (de) * | 1993-01-19 | 1996-06-27 | Dester Kaelte Anlagenbau Gmbh | Kältemaschine |
AU694420B2 (en) * | 1993-03-11 | 1998-07-23 | Medinol Ltd | Stent |
ATE164056T1 (de) * | 1993-04-23 | 1998-04-15 | Schneider Europ Ag | Stent mit einer beschichtung aus elastischem material und verfahren zum anbringen der beschichtung auf dem stent |
US5397355A (en) * | 1994-07-19 | 1995-03-14 | Stentco, Inc. | Intraluminal stent |
-
1994
- 1994-12-23 DE DE4446036A patent/DE4446036C2/de not_active Expired - Lifetime
-
1995
- 1995-12-19 EP EP95942643A patent/EP0749290B1/de not_active Expired - Lifetime
- 1995-12-19 DE DE59510558T patent/DE59510558D1/de not_active Expired - Lifetime
- 1995-12-19 WO PCT/DE1995/001849 patent/WO1996019952A2/de active IP Right Grant
- 1995-12-19 JP JP52012396A patent/JP3734505B2/ja not_active Expired - Lifetime
-
1996
- 1996-11-27 US US08/758,216 patent/US5814063A/en not_active Expired - Lifetime
Non-Patent Citations (1)
Title |
---|
See references of WO9619952A2 * |
Also Published As
Publication number | Publication date |
---|---|
EP0749290B1 (de) | 2003-02-19 |
JPH09509606A (ja) | 1997-09-30 |
DE59510558D1 (de) | 2003-03-27 |
WO1996019952A3 (de) | 1996-09-06 |
DE4446036C2 (de) | 1999-06-02 |
JP3734505B2 (ja) | 2006-01-11 |
US5814063A (en) | 1998-09-29 |
WO1996019952A2 (de) | 1996-07-04 |
DE4446036A1 (de) | 1996-07-04 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EP0749290B1 (de) | Platzhalter zum anordnen in einer körperröhre | |
EP0746269B1 (de) | Platzhalter zum anordnen in einer körperröhre | |
EP0734698B1 (de) | Stent zur transluminalen Implantation in Hohlorgane | |
DE69934244T2 (de) | Spiralförmiger stent | |
DE69727178T2 (de) | Profilierter Stent und Herstellungsverfahren dafür | |
DE68924625T3 (de) | Radial ausdehnbare Endoprothese. | |
DE69533985T2 (de) | Stent | |
DE4240177C2 (de) | Selbstexpandierender Stent für Hohlorgane | |
DE69729633T2 (de) | Implantierbare vorrichtung zum festerhalten oder wiederherstellen eines normalen körpergefässquerschnittes | |
DE69733111T2 (de) | Kompositstent | |
DE69831935T2 (de) | Bistabiler federaufbau für ein stent | |
DE69309132T2 (de) | Instraluminarer Stent | |
EP1023008B1 (de) | Aufgeweiteter stent und verfahren zum herstellen desselben | |
DE69420549T2 (de) | Elastische prothese zur verbreiterung eines gefässes, insbesondere eines blutgefässes, und verfahren zu deren herstellung | |
EP1184007A2 (de) | Spannungsoptimierter Stent | |
DE19633901A1 (de) | Gefäßstütze in Form einer Schlauchabschnitts-artigen Stützstruktur | |
DE69023277T2 (de) | Orthodontische Schraubenfeder. | |
EP0481365A1 (de) | Vorrichtung zum Aufweiten einer Stenose in einer Körperröhre | |
DE60020979T2 (de) | Einführsystem mit reduziertem profil | |
DE10253633A1 (de) | Tragstruktur | |
DE10050970A1 (de) | Stent | |
DE102018133345B4 (de) | Stent | |
WO2005051238A1 (de) | Kompressionsmanschette | |
EP0682922B1 (de) | Selbstexpandierender Stent für Hohlorgane | |
DE19524653A1 (de) | Platzhalter zum Anordnen in einer Körperröhre |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): DE ES FR GB IT |
|
17P | Request for examination filed |
Effective date: 19960806 |
|
RAP1 | Party data changed (applicant data changed or rights of an application transferred) |
Owner name: FREITAG, LUTZ DR. |
|
RIN1 | Information on inventor provided before grant (corrected) |
Inventor name: FREITAG, LUTZ DR. |
|
GRAH | Despatch of communication of intention to grant a patent |
Free format text: ORIGINAL CODE: EPIDOS IGRA |
|
GRAH | Despatch of communication of intention to grant a patent |
Free format text: ORIGINAL CODE: EPIDOS IGRA |
|
GRAA | (expected) grant |
Free format text: ORIGINAL CODE: 0009210 |
|
RAP1 | Party data changed (applicant data changed or rights of an application transferred) |
Owner name: ALVEOLUS, INC. |
|
RIN1 | Information on inventor provided before grant (corrected) |
Inventor name: FREITAG, LUTZ DR. |
|
AK | Designated contracting states |
Designated state(s): DE ES FR GB IT |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: IT Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRE;WARNING: LAPSES OF ITALIAN PATENTS WITH EFFECTIVE DATE BEFORE 2007 MAY HAVE OCCURRED AT ANY TIME BEFORE 2007. THE CORRECT EFFECTIVE DATE MAY BE DIFFERENT FROM THE ONE RECORDED.SCRIBED TIME-LIMIT Effective date: 20030219 Ref country code: GB Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20030219 Ref country code: FR Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20030219 |
|
REG | Reference to a national code |
Ref country code: GB Ref legal event code: FG4D Free format text: NOT ENGLISH |
|
REF | Corresponds to: |
Ref document number: 59510558 Country of ref document: DE Date of ref document: 20030327 Kind code of ref document: P |
|
GBV | Gb: ep patent (uk) treated as always having been void in accordance with gb section 77(7)/1977 [no translation filed] |
Effective date: 20030219 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: ES Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20030828 |
|
PLBE | No opposition filed within time limit |
Free format text: ORIGINAL CODE: 0009261 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: NO OPPOSITION FILED WITHIN TIME LIMIT |
|
EN | Fr: translation not filed | ||
26N | No opposition filed |
Effective date: 20031120 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: DE Payment date: 20141222 Year of fee payment: 20 |
|
REG | Reference to a national code |
Ref country code: DE Ref legal event code: R071 Ref document number: 59510558 Country of ref document: DE |