EE05171B1 - Peroraalne ravimvorm, mis sisaldab opioidagonisti vabanevas vormis ja eraldatud opioidantagonisti, meetod selle valmistamiseks ning selle kasutamine meditsiinis - Google Patents
Peroraalne ravimvorm, mis sisaldab opioidagonisti vabanevas vormis ja eraldatud opioidantagonisti, meetod selle valmistamiseks ning selle kasutamine meditsiinisInfo
- Publication number
- EE05171B1 EE05171B1 EEP200200437A EEP200200437A EE05171B1 EE 05171 B1 EE05171 B1 EE 05171B1 EE P200200437 A EEP200200437 A EE P200200437A EE P200200437 A EEP200200437 A EE P200200437A EE 05171 B1 EE05171 B1 EE 05171B1
- Authority
- EE
- Estonia
- Prior art keywords
- medicine
- preparation
- oral dosage
- isolated
- liberated
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
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- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
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- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
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- A61K9/1605—Excipients; Inactive ingredients
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- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
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- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
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- A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
- A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
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- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
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- Inorganic Chemistry (AREA)
- Toxicology (AREA)
- Psychiatry (AREA)
- Rheumatology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US18136900P | 2000-02-08 | 2000-02-08 | |
PCT/US2001/004346 WO2001058451A1 (en) | 2000-02-08 | 2001-02-08 | Tamper-resistant oral opioid agonist formulations |
Publications (2)
Publication Number | Publication Date |
---|---|
EE200200437A EE200200437A (et) | 2003-12-15 |
EE05171B1 true EE05171B1 (et) | 2009-06-15 |
Family
ID=22663996
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EEP200200437A EE05171B1 (et) | 2000-02-08 | 2001-02-08 | Peroraalne ravimvorm, mis sisaldab opioidagonisti vabanevas vormis ja eraldatud opioidantagonisti, meetod selle valmistamiseks ning selle kasutamine meditsiinis |
Country Status (35)
Country | Link |
---|---|
US (15) | US6696088B2 (es) |
EP (6) | EP2092936B1 (es) |
JP (10) | JP2003522144A (es) |
KR (2) | KR20020071032A (es) |
CN (3) | CN100563656C (es) |
AP (1) | AP1665A (es) |
AT (1) | ATE431145T1 (es) |
AU (2) | AU776904B2 (es) |
BG (1) | BG65828B1 (es) |
BR (2) | BRPI0108380B8 (es) |
CA (1) | CA2400567C (es) |
CY (2) | CY1109270T1 (es) |
CZ (1) | CZ299991B6 (es) |
DE (1) | DE60138706D1 (es) |
DK (5) | DK2517710T3 (es) |
EA (1) | EA004876B1 (es) |
EE (1) | EE05171B1 (es) |
ES (5) | ES2540103T3 (es) |
GE (1) | GEP20053614B (es) |
HK (3) | HK1051487A1 (es) |
HU (2) | HU229705B1 (es) |
IL (5) | IL151057A0 (es) |
ME (1) | ME00398B (es) |
MX (2) | MXPA02007686A (es) |
NO (2) | NO324717B1 (es) |
NZ (1) | NZ520554A (es) |
OA (1) | OA12215A (es) |
PL (1) | PL210845B1 (es) |
PT (6) | PT2092936E (es) |
RS (1) | RS50407B (es) |
SI (5) | SI1299104T1 (es) |
SK (1) | SK287107B6 (es) |
TW (1) | TWI292317B (es) |
UA (1) | UA79069C2 (es) |
WO (2) | WO2001058451A1 (es) |
Families Citing this family (331)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6375957B1 (en) | 1997-12-22 | 2002-04-23 | Euro-Celtique, S.A. | Opioid agonist/opioid antagonist/acetaminophen combinations |
BR9813827A (pt) | 1997-12-22 | 2000-10-10 | Euro Celtique Sa | Analgésico opióide aplicável em mamìferos e método para impedir o uso oral abusivo de uma formulação opióide oral |
JP2001526229A (ja) * | 1997-12-22 | 2001-12-18 | ユーロ−セルティーク,エス.エイ. | オピオイド投薬剤形の乱用を防止する方法 |
US10179130B2 (en) | 1999-10-29 | 2019-01-15 | Purdue Pharma L.P. | Controlled release hydrocodone formulations |
ATE526950T1 (de) | 1999-10-29 | 2011-10-15 | Euro Celtique Sa | Hydrocodon-formulierungen mit gesteuerter freisetzung |
MXPA02007686A (es) * | 2000-02-08 | 2003-03-27 | Euro Celtique Sa | Formulaciones orales y resistentes a intervenciones de agonistas opioides.. |
EP2932964A1 (en) | 2000-10-30 | 2015-10-21 | Euro-Celtique S.A. | Controlled release hydrocodone formulations |
US7858118B2 (en) * | 2001-04-11 | 2010-12-28 | Galephar Pharmaceutical Research, Inc. | Extended release composition containing Tramadol |
ATE493130T1 (de) * | 2001-05-11 | 2011-01-15 | Endo Pharmaceuticals Inc | Opioid enthaltende arzneiform gegen missbrauch |
WO2002092059A1 (en) * | 2001-05-11 | 2002-11-21 | Endo Pharmaceuticals, Inc. | Abuse-resistant opioid dosage form |
WO2003002100A1 (en) * | 2001-06-26 | 2003-01-09 | Farrell John J | Tamper-proof narcotic delivery system |
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