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EA201490715A1 - Рнк-интерференция для борьбы с грибами и оомицетами путем ингибирования гена сахаропиндегидрогеназы - Google Patents

Рнк-интерференция для борьбы с грибами и оомицетами путем ингибирования гена сахаропиндегидрогеназы

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Publication number
EA201490715A1
EA201490715A1 EA201490715A EA201490715A EA201490715A1 EA 201490715 A1 EA201490715 A1 EA 201490715A1 EA 201490715 A EA201490715 A EA 201490715A EA 201490715 A EA201490715 A EA 201490715A EA 201490715 A1 EA201490715 A1 EA 201490715A1
Authority
EA
Eurasian Patent Office
Prior art keywords
inhibiting
rna interference
gene
saharopindehydrogenase
oomicets
Prior art date
Application number
EA201490715A
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English (en)
Other versions
EA028662B1 (ru
Inventor
Тома Делебарр
Сесиль Дорме
Бернд Эссигманн
Фредерик Шмитт
Франсуа Виллалба
Эрик Паже
Original Assignee
Байер Интеллекчуал Проперти Гмбх
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Байер Интеллекчуал Проперти Гмбх filed Critical Байер Интеллекчуал Проперти Гмбх
Publication of EA201490715A1 publication Critical patent/EA201490715A1/ru
Publication of EA028662B1 publication Critical patent/EA028662B1/ru

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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1137Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/02Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
    • A01N43/04Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom
    • A01N43/14Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom six-membered rings
    • A01N43/16Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom six-membered rings with oxygen as the ring hetero atom
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N63/00Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
    • A01N63/60Isolated nucleic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088Compounds having three or more nucleosides or nucleotides
    • A61K31/713Double-stranded nucleic acids or oligonucleotides
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8216Methods for controlling, regulating or enhancing expression of transgenes in plant cells
    • C12N15/8218Antisense, co-suppression, viral induced gene silencing [VIGS], post-transcriptional induced gene silencing [PTGS]
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8279Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
    • C12N15/8282Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for fungal resistance
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    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0012Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0026Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on CH-NH groups of donors (1.5)
    • C12N9/0028Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on CH-NH groups of donors (1.5) with NAD or NADP as acceptor (1.5.1)
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    • C12Y105/00Oxidoreductases acting on the CH-NH group of donors (1.5)
    • C12Y105/01Oxidoreductases acting on the CH-NH group of donors (1.5) with NAD+ or NADP+ as acceptor (1.5.1)
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    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/10Type of nucleic acid
    • C12N2310/14Type of nucleic acid interfering N.A.
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A40/00Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
    • Y02A40/10Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
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  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
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  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Agronomy & Crop Science (AREA)
  • Environmental Sciences (AREA)
  • Dentistry (AREA)
  • Pest Control & Pesticides (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pretreatment Of Seeds And Plants (AREA)

Abstract

Настоящее изобретение относится к борьбе с патогенами растений, в частности грибами или оомицетами, путем ингибирования одной или нескольких биологических функций, в частности путем ингибирования гена(ов) сахаропиндегидрогеназы при помощи РНК-интерференции. Изобретение относится к способам и композициям, в которых используют для указанной борьбы РНК-интерференцию генов-мишеней патогенов растений. Изобретение также относится к способам получения трансгенных растений, толерантных к указанным патогенам растений, и к трансгенным растениям и к семенам, полученным из них.
EA201490715A 2011-10-04 2012-10-03 Рнк-интерференция для борьбы с грибами и оомицетами путем ингибирования гена сахаропиндегидрогеназы EA028662B1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP11356013 2011-10-04
US201261661062P 2012-06-18 2012-06-18
PCT/EP2012/069521 WO2013050410A1 (en) 2011-10-04 2012-10-03 RNAi FOR THE CONTROL OF FUNGI AND OOMYCETES BY INHIBITING SACCHAROPINE DEHYDROGENASE GENE

Publications (2)

Publication Number Publication Date
EA201490715A1 true EA201490715A1 (ru) 2014-07-30
EA028662B1 EA028662B1 (ru) 2017-12-29

Family

ID=48043183

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201490715A EA028662B1 (ru) 2011-10-04 2012-10-03 Рнк-интерференция для борьбы с грибами и оомицетами путем ингибирования гена сахаропиндегидрогеназы

Country Status (15)

Country Link
US (2) US20150082495A1 (ru)
EP (1) EP2764101B1 (ru)
JP (1) JP6255344B2 (ru)
CN (1) CN103842507A (ru)
AR (1) AR088113A1 (ru)
AU (1) AU2012320554B2 (ru)
BR (1) BR112014008059A2 (ru)
CA (1) CA2844868A1 (ru)
EA (1) EA028662B1 (ru)
ES (1) ES2628436T3 (ru)
IN (1) IN2014DN03473A (ru)
PL (1) PL2764101T3 (ru)
UA (1) UA115132C2 (ru)
WO (1) WO2013050410A1 (ru)
ZA (1) ZA201403196B (ru)

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WO2015004174A1 (en) * 2013-07-10 2015-01-15 Basf Se Rnai for the control of phytopathogenic fungi and oomycetes by inhibiting the expression of cyp51 genes
EP3101135A1 (en) 2015-06-01 2016-12-07 Universität Hamburg Method of conferring resistance against a fusarium plant disease
WO2017191580A1 (en) * 2016-05-03 2017-11-09 University Of Manitoba Plants and methods for controlling fungal plant pathogens
US10392620B2 (en) 2016-11-10 2019-08-27 Dow Agrosciences Llc Cytochrome B (CYTB) nucleic acid molecules that control pathogens
US10913955B2 (en) 2017-10-10 2021-02-09 Dow Agrosciences Llc Aldehyde dehydrogenase (ALDH1) nucleic acid molecules that control pathogens
EP3802521A1 (de) 2018-06-04 2021-04-14 Bayer Aktiengesellschaft Herbizid wirksame bizyklische benzoylpyrazole
CA3109666A1 (en) * 2018-08-17 2020-02-20 Centre National De La Recherche Scientifique (Cnrs) Rna-based therapeutic methods to protect animals against pathogenic bacteria and / or promote beneficial effects of symbiotic and commensal bacteria
CN111647572A (zh) * 2020-06-01 2020-09-11 中国科学院天津工业生物技术研究所 源于里氏木霉的还原酶及其编码基因和用途
WO2022146195A1 (ru) * 2020-12-30 2022-07-07 Общество с ограниченной ответственностью "Международная лаборатория "Резистом" ИНТЕРФЕРИРУЮЩАЯ дцРНК ДЛЯ ЗАЩИТЫ РАСТЕНИЙ ОТ ФИТОФТОРОЗА

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ES2628436T3 (es) 2017-08-02
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ZA201403196B (en) 2015-07-29
US20190382770A1 (en) 2019-12-19
AU2012320554A1 (en) 2014-05-22
BR112014008059A2 (pt) 2018-04-24
IN2014DN03473A (ru) 2015-06-05
EP2764101B1 (en) 2017-03-29
AR088113A1 (es) 2014-05-07
JP2015501139A (ja) 2015-01-15
US20150082495A1 (en) 2015-03-19
WO2013050410A1 (en) 2013-04-11
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CN103842507A (zh) 2014-06-04
UA115132C2 (uk) 2017-09-25

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