[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

DK2190289T3 - Isoxazolinforbindelser og deres anvendelse som antiparasitika - Google Patents

Isoxazolinforbindelser og deres anvendelse som antiparasitika

Info

Publication number
DK2190289T3
DK2190289T3 DK08803041.6T DK08803041T DK2190289T3 DK 2190289 T3 DK2190289 T3 DK 2190289T3 DK 08803041 T DK08803041 T DK 08803041T DK 2190289 T3 DK2190289 T3 DK 2190289T3
Authority
DK
Denmark
Prior art keywords
antiparasitics
isoxazoline compounds
isoxazoline
compounds
Prior art date
Application number
DK08803041.6T
Other languages
English (en)
Inventor
Anja Regina Heckeroth
Juergen Lutz
Heike Williams
Hartmut Zoller
Takeshi Mita
Christina Mertens
Original Assignee
Intervet Int Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40152741&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK2190289(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Intervet Int Bv filed Critical Intervet Int Bv
Application granted granted Critical
Publication of DK2190289T3 publication Critical patent/DK2190289T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/04—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
    • A01N43/80—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,2
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
    • A01N47/10—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof
    • A01N47/12—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof containing a —O—CO—N< group, or a thio analogue thereof, neither directly attached to a ring nor the nitrogen atom being a member of a heterocyclic ring
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
    • A01N47/10—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof
    • A01N47/18—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof containing a —O—CO—N< group, or a thio analogue thereof, directly attached to a heterocyclic or cycloaliphatic ring
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N53/00—Biocides, pest repellants or attractants, or plant growth regulators containing cyclopropane carboxylic acids or derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/14—Ectoparasiticides, e.g. scabicides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Plant Pathology (AREA)
  • Agronomy & Crop Science (AREA)
  • Environmental Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Dentistry (AREA)
  • Pest Control & Pesticides (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DK08803041.6T 2007-08-17 2008-08-15 Isoxazolinforbindelser og deres anvendelse som antiparasitika DK2190289T3 (da)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US95644807P 2007-08-17 2007-08-17
EP07016152 2007-08-17
EP07150309 2007-12-21
US8044408P 2008-07-14 2008-07-14
PCT/EP2008/060732 WO2009024541A2 (en) 2007-08-17 2008-08-15 Isoxazoline compositions and their use as antiparasitics

Publications (1)

Publication Number Publication Date
DK2190289T3 true DK2190289T3 (da) 2013-07-29

Family

ID=40152741

Family Applications (2)

Application Number Title Priority Date Filing Date
DK18205103.7T DK3473101T3 (da) 2007-08-17 2008-08-15 Isoxazolinsammensætninger og deres anvendelse som antiparasitik for feliner
DK08803041.6T DK2190289T3 (da) 2007-08-17 2008-08-15 Isoxazolinforbindelser og deres anvendelse som antiparasitika

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK18205103.7T DK3473101T3 (da) 2007-08-17 2008-08-15 Isoxazolinsammensætninger og deres anvendelse som antiparasitik for feliner

Country Status (20)

Country Link
US (6) US20110059988A1 (da)
EP (3) EP2190289B1 (da)
JP (4) JP5411135B2 (da)
KR (3) KR101725320B1 (da)
CN (2) CN103705509A (da)
AU (2) AU2008290581C1 (da)
BR (2) BR122020005235B1 (da)
CA (1) CA2694919C (da)
DK (2) DK3473101T3 (da)
ES (2) ES2417157T3 (da)
HK (1) HK1143037A1 (da)
MX (2) MX351346B (da)
NO (1) NO2016018I1 (da)
NZ (2) NZ583045A (da)
PL (2) PL2545777T5 (da)
PT (1) PT2190289E (da)
RU (3) RU2481837C2 (da)
TW (1) TWI556741B (da)
WO (1) WO2009024541A2 (da)
ZA (1) ZA201203080B (da)

Families Citing this family (112)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1930136B (zh) 2004-03-05 2012-02-08 日产化学工业株式会社 异*唑啉取代苯甲酰胺化合物及有害生物防除剂
TW200803740A (en) * 2005-12-16 2008-01-16 Du Pont 5-aryl isoxazolines for controlling invertebrate pests
TWI412322B (zh) 2005-12-30 2013-10-21 Du Pont 控制無脊椎害蟲之異唑啉
WO2008108448A1 (ja) * 2007-03-07 2008-09-12 Nissan Chemical Industries, Ltd. イソキサゾリン置換ベンズアミド化合物及び有害生物防除剤
AU2008261793A1 (en) * 2007-06-13 2008-12-18 E. I. Du Pont De Nemours And Company Isoxazoline insecticides
MX361762B (es) * 2007-06-27 2018-12-17 Du Pont Metodo de control de plagas en animales.
TWI649303B (zh) 2007-08-17 2019-02-01 杜邦股份有限公司 製備４-乙醯基-ｎ-〔２-側氧基-２-〔（２，２，２-三氟乙基）胺基〕乙基〕-１-萘甲醯胺之化合物及方法
TWI556741B (zh) * 2007-08-17 2016-11-11 英特威特國際股份有限公司 異唑啉組成物及其作為抗寄生蟲藥上的應用
TWI583664B (zh) 2008-04-09 2017-05-21 杜邦股份有限公司 羰基化合物及其製備方法
AU2009270255B2 (en) 2008-07-09 2013-12-12 Nissan Chemical Corporation Process for production of isoxazoline-substituted benzoic acid amide compound
JP2011527307A (ja) 2008-07-09 2011-10-27 ビーエーエスエフ ソシエタス・ヨーロピア イソオキサゾリン化合物ｉを含む殺有害生物活性混合物
MX2011001851A (es) 2008-08-22 2011-03-21 Syngenta Participations Ag Compuestos insecticidas.
BRPI0917369A2 (pt) 2008-08-22 2015-08-04 Syngenta Participations Ag Compostos inseticidas
JP2012501989A (ja) 2008-09-04 2012-01-26 シンジェンタ パーティシペーションズ アクチェンゲゼルシャフト 殺虫化合物
EP3498696A1 (en) 2008-11-14 2019-06-19 Merial, Inc. Enantiomerically enriched aryloazol-2-yl cyanoethylamino parasiticidal compounds
KR101660068B1 (ko) 2008-11-19 2016-09-26 메리얼 인코포레이티드 기생충 감염 치료를 위한 1-아릴피라졸 단독 또는 포름아미딘과의 조합을 포함하는 조성물
US8426460B2 (en) 2008-12-04 2013-04-23 Merial Limited Dimeric avermectin and milbemycin derivatives
EP2424862B1 (en) 2009-04-30 2014-10-08 Basf Se Process for preparing substituted isoxazoline compounds and their precursors
TWI487486B (zh) 2009-12-01 2015-06-11 Syngenta Participations Ag 以異唑啉衍生物為主之殺蟲化合物
NZ600922A (en) 2009-12-17 2013-10-25 Merial Ltd Anti parasitic dihydroazole compounds and compositions comprising same
UA108641C2 (uk) 2010-04-02 2015-05-25 Паразитицидна композиція, яка містить чотири активних агенти, та спосіб її застосування
US8598087B2 (en) 2010-05-27 2013-12-03 E. I. Du Pont De Nemours And Company Crystalline form of 4-[5-[3-chloro-5-(trifluoromethyl)phenyl]-4, 5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-N-[2-0X0-2-[(2,2,2-trifluoroethyl)amino]ethyl]-1- naph-thalenecarboxamide
TW201211057A (en) * 2010-06-11 2012-03-16 Syngenta Participations Ag Process for the preparation of dihydropyrrole derivatives
US9085541B2 (en) 2010-06-23 2015-07-21 Basf Se Process for producing imine compounds for combating invertebrate pests
WO2012007426A1 (en) 2010-07-13 2012-01-19 Basf Se Azoline substituted isoxazoline benzamide compounds for combating animal pests
WO2012059441A2 (en) 2010-11-03 2012-05-10 Basf Se Method for preparing substituted isoxazoline compounds and their precursors 4-chloro, 4-bromo- or 4-iodobenzaldehyde oximes
JP2014015397A (ja) * 2010-11-04 2014-01-30 Nippon Soda Co Ltd 動物用外部寄生虫防除剤
DE102010063691A1 (de) 2010-12-21 2012-06-21 Bayer Animal Health Gmbh Ektoparasitizide Wirkstoffkombinationen
HUE058290T2 (hu) 2010-12-27 2022-07-28 Intervet Int Bv Topikális lokalizált izoxazolin formuláció, amely tartalmaz glikofurolt
NZ745590A (en) * 2010-12-27 2020-02-28 Intervet Int Bv Topical localized isoxazoline formulation
DK2658542T3 (da) * 2010-12-27 2022-03-28 Intervet Int Bv Topisk lokaliseret isoxazolinformulering
WO2012155352A1 (en) 2011-05-19 2012-11-22 Eli Lilly And Company Dihydroisoxazole compounds, parasiticidal uses and formulations thereof
AU2012275435B2 (en) 2011-06-27 2016-07-21 Boehringer Ingelheim Animal Health USA Inc. Amido-pyridyl ether compounds and compositions and their use against parasites
KR102081036B1 (ko) 2011-09-12 2020-02-24 뵈링거 잉겔하임 애니멀 헬스 유에스에이 인코포레이티드 이속사졸 활성화제를 포함하는 구충 조성물, 이의 용도 및 구충 방법
CN104023720B (zh) 2011-11-17 2016-10-26 梅里亚有限公司 包含芳基吡唑和取代咪唑的组合物，其方法和用途
AR088669A1 (es) * 2011-11-21 2014-06-25 Lilly Co Eli Derivados de dihidrodibenzo[c][1,2]oxaborol y dihidroisoxazol utiles para el control de ectoparasitos
US20140343085A1 (en) * 2011-11-29 2014-11-20 Novartis Ag Use of aryl derivatives for controlling ectoparasites
CN104053660B (zh) 2011-12-02 2016-12-28 梅里亚有限公司 长效的可注射的莫昔克丁配制剂和新的莫昔克丁晶型
DK2811998T3 (da) 2012-02-06 2019-02-25 Merial Inc Parasiticide orale veterinære sammensætninger omfattende systemisk virkende aktivstoffer, fremgangsmåder og anvendelser deraf
JO3626B1 (ar) 2012-02-23 2020-08-27 Merial Inc تركيبات موضعية تحتوي على فيبرونيل و بيرميثرين و طرق استخدامها
CN109010296A (zh) 2012-04-04 2018-12-18 英特维特国际股份有限公司 异噁唑啉化合物的固体口服药物组合物
UA115981C2 (uk) 2012-04-20 2018-01-25 Меріал, Інк. Паразитицидні композиції, що містять похідні бензимідазолу, способи їх одержання та застосування
AU2013245478A1 (en) * 2012-11-01 2014-05-15 Sumitomo Chemical Company, Limited Method for administering agent for controlling ectoparasite to dog
SI2922845T1 (sl) 2012-11-20 2018-10-30 Merial, Inc. Antihelmintske spojine in sestavki ter postopek za njihovo uporabo
US9532946B2 (en) 2012-11-20 2017-01-03 Intervet Inc. Manufacturing of semi-plastic pharmaceutical dosage units
LT2953942T (lt) 2013-02-06 2018-02-12 Bayer Cropscience Aktiengesellschaft Halogenpakeistieji pirazolo dariniai kaip pesticidai
CA2906295C (en) 2013-03-15 2019-01-22 Argenta Manufacturing Limited Chewable formulation
EP3030084A4 (en) 2013-07-29 2016-07-27 Attillaps Holdings Organophosphates for the treatment of skin disorders
US11446241B2 (en) 2013-07-29 2022-09-20 Attillaps Holdings Inc. Treatment of ophthalmological conditions with acetylcholinesterase inhibitors
US9371293B2 (en) 2013-10-25 2016-06-21 Sumitomo Chemical Company, Limited Isoxazoline compound composition
CA2929234C (en) 2013-11-01 2022-01-11 Merial Limited Antiparisitic and pesticidal isoxazoline compounds
US9655884B2 (en) 2013-12-10 2017-05-23 Intervet Inc. Antiparasitic use of isoxazoline compounds
CN105813651B (zh) * 2013-12-20 2021-11-23 英特维特国际股份有限公司 异噁唑啉组合物及其在预防或治疗动物的寄生虫侵袭中的用途
JP6506763B2 (ja) * 2013-12-20 2019-04-24 インターベット インターナショナル ベー． フェー． 家禽類における節足動物侵襲の処置または予防のためのイソオキサゾリン誘導体の使用
CA2935646A1 (en) 2014-01-03 2015-07-09 Bayer Animal Health Gmbh Novel pyrazolyl-heteroarylamides as pesticides
EP3131398B1 (en) 2014-04-17 2019-10-23 Boehringer Ingelheim Animal Health USA Inc. Use of malononitrile compounds for protecting animals from parasites
NZ726874A (en) 2014-05-19 2018-03-23 Merial Inc Anthelmintic compounds
BR122020023385B1 (pt) 2014-06-19 2021-05-25 Merial, Inc composições parasiticidas compreendendo derivados de indol, métodos e usos dos mesmos
LT3157534T (lt) 2014-06-19 2022-09-12 Attillaps Holdings Acetilcholinesterazės inhibitoriai, skirti dermatologinių būklių gydymui
WO2016008830A1 (de) 2014-07-15 2016-01-21 Bayer Cropscience Aktiengesellschaft Aryl-triazolyl-pyridine als schädlingsbekämpfungsmittel
US10864193B2 (en) 2014-10-31 2020-12-15 Boehringer Ingelheim Animal Health USA Inc. Parasiticidal compositions comprising fipronil at high concentrations
BR112017013286A2 (pt) * 2014-12-22 2018-03-06 Intervet International B.V. composto de isoxazolina, e, uso de um composto de isoxazolina.
UY36570A (es) 2015-02-26 2016-10-31 Merial Inc Formulaciones inyectables de acción prolongada que comprenden un agente activo isoxazolina, métodos y usos de las mismas
AU2016246598B2 (en) 2015-04-08 2020-07-23 Boehringer lngelheim Vetmedica GMBH Extended release injectable formulations comprising an isoxazoline active agent, methods and uses thereof
RU2707298C2 (ru) 2015-05-20 2019-11-26 Мериал, Инк. Противогельминтные депсипептидные соединения
JP6933983B2 (ja) * 2015-06-23 2021-09-08 インターベット インターナショナル ベー． フェー． 衛生化飲料水と共に使用するためのビタミンｅを含有するイソオキサゾリン溶液
UY37137A (es) * 2016-02-24 2017-09-29 Merial Inc Compuestos antiparasitarios de isoxazolina, formulaciones inyectables de acción prolongada que los comprenden, métodos y usos de los mismos
EP3440062B1 (en) 2016-04-06 2021-10-06 Boehringer Ingelheim Animal Health USA Inc. Process for the preparation of enantiomerically enriched isoxazoline compounds - crystalline toluene solvate of (s)-afoxolaner
WO2018039508A1 (en) 2016-08-25 2018-03-01 Merial, Inc. Method for reducing unwanted effects in parasiticidal treatments
EP3525590A1 (en) 2016-10-14 2019-08-21 Boehringer Ingelheim Animal Health USA Inc. Pesticidal and parasiticidal vinyl isoxazoline compounds
BR112019009977A2 (pt) 2016-11-16 2019-08-27 Boehringer Ingelheim Animal Health Usa Inc compostos depsipeptídicos anti-helmínticos
CN107535503A (zh) * 2017-07-21 2018-01-05 陕西康禾立丰生物科技药业有限公司 一种含有氟噁唑酰胺和新烟碱类的杀虫组合物
HUE061497T2 (hu) 2017-08-14 2023-07-28 Boehringer Ingelheim Animal Health Usa Inc Peszticid és paraziticid hatású pirazol-izoxazolin vegyületek
CN107593723A (zh) * 2017-09-29 2018-01-19 北京科发伟业农药技术中心 一种含fluxametamide的组合物
CN111295375A (zh) 2017-11-07 2020-06-16 英特维特国际股份有限公司 制备大尺寸异噁唑啉粒子的方法
AU2018363682B2 (en) 2017-11-07 2023-11-23 Intervet International B.V. Injectable isoxazoline pharmaceutical compositions and their use against parasite infestation
MX2020006055A (es) 2017-12-12 2020-08-20 Intervet Int Bv Composiciones farmaceuticas implantables de isoxazolina y usos de las mismas.
US10835517B2 (en) 2017-12-15 2020-11-17 Tarsus Pharmaceuticals, Inc. Methods for treating ocular demodex using isoxazoline parasiticide formulations
AR113997A1 (es) 2017-12-21 2020-07-08 Intervet Int Bv Composiciones antiparasitarias para unción dorsal continua
US11583545B2 (en) 2018-02-08 2023-02-21 Boehringer Ingelheim Animal Health USA Inc. Parasiticidal compositions comprising eprinomectin and praziquantel, methods and uses thereof
WO2020014068A1 (en) 2018-07-09 2020-01-16 Boehringer Ingelheim Animal Health USA Inc. Anthelminthic heterocyclic compounds
EP3883648A1 (en) 2018-11-20 2021-09-29 Boehringer Ingelheim Animal Health USA Inc. Indazolylcyanoethylamino compound, compositions of same, method of making, and methods of using thereof
NZ776819A (en) 2019-01-16 2023-04-28 Boehringer Ingelheim Animal Health Usa Inc Topical compositions comprising a neonicotinoid and a macrocyclic lactone, methods and uses thereof
WO2020180635A1 (en) 2019-03-01 2020-09-10 Boehringer Ingelheim Animal Health USA Inc. Injectable clorsulon compositions, methods and uses thereof
CA3133100A1 (en) 2019-03-19 2020-09-24 Boehringer Ingelheim Animal Health USA Inc. Anthelmintic aza-benzothiophene and aza-benzofuran compounds
WO2020202111A1 (en) * 2019-04-04 2020-10-08 Tarsus Pharmaceuticals, Inc. Systemic isoxazoline parasiticides for vector-borne and viral disease treatment or prophylaxis
BR112021021649A2 (pt) 2019-05-03 2021-12-21 Intervet Int Bv Composições farmacêuticas injetáveis e usos das mesmas
CN112174904B (zh) * 2019-07-01 2023-08-18 沈阳化工大学 一种异噁唑啉类化合物及其应用
US20220323421A1 (en) 2019-07-22 2022-10-13 Intervet Inc. Soft Chewable Veterinary Dosage Form
WO2021122521A1 (en) 2019-12-16 2021-06-24 Intervet International B.V. Composition for lice control in poultry
AU2020409532A1 (en) 2019-12-16 2022-05-12 Intervet International B.V. Composition for lice control
WO2021122515A1 (en) 2019-12-16 2021-06-24 Intervet International B.V. Parasite control in ruminants
CN115666514A (zh) 2020-05-20 2023-01-31 英特维特国际股份有限公司 可注射的药物组合物及其用途
WO2021242481A1 (en) 2020-05-28 2021-12-02 Boehringer Ingelheim Animal Health USA Inc. Bi-modal release intra-ruminal capsule device and methods of use thereof
KR20230028268A (ko) 2020-05-29 2023-02-28 뵈링거 잉겔하임 애니멀 헬스 유에스에이 인코포레이티드 구충성 헤테로시클릭 화합물
CN111657292A (zh) * 2020-06-03 2020-09-15 浙江中山化工集团股份有限公司 一种含有氟噁唑酰胺和高效氯氰菊酯的杀虫组合物
CN111909143B (zh) * 2020-07-30 2021-10-29 山东省联合农药工业有限公司 一种异噁唑啉取代的苯甲酰胺类衍生物及其制备方法与用途
CA3201608A1 (en) 2020-12-18 2022-06-23 Boehringer Ingelheim Animal Health USA Inc. Boron containing pyrazole compounds, compositions comprising them, methods and uses thereof
CA3205997A1 (en) 2020-12-21 2022-06-30 University Of Georgia Research Foundation Inc. Parasiticidal collar comprising isoxazoline compounds
US20240116854A1 (en) 2021-01-27 2024-04-11 Intervet Inc. Cyclopropylamide compounds against parasites in fish
WO2022162016A1 (en) 2021-01-27 2022-08-04 Intervet International B.V. Cyclopropylamide compounds against parasites in fish
WO2022192631A1 (en) * 2021-03-11 2022-09-15 In The Bowl Animal Health, Inc. Oral canine feed and methods for controlling tick infestations in a canine
WO2022192623A1 (en) * 2021-03-11 2022-09-15 In The Bowl Animal Health, Inc. Oral canine feed and methods for controlling flea infestations in a canine
CA3217124A1 (en) * 2021-04-30 2022-11-03 John O'halloran Use of isoxazoline for protection against parasitic pests in fish
WO2022269042A1 (en) 2021-06-25 2022-12-29 Intervet International B.V. Palatable veterinary compositions
CN113563322B (zh) * 2021-07-26 2023-07-07 海利尔药业集团股份有限公司 一种取代的苯甲酰胺类异噁唑啉衍生物或其作为农药可接受的盐、组合物及其用途
KR102660238B1 (ko) * 2021-12-20 2024-04-25 주식회사경농 다이하이드로아이소옥사졸 유도체 화합물 및 이를 포함하는 살충제 조성물
WO2023156938A1 (en) 2022-02-17 2023-08-24 Boehringer Ingelheim Vetmedica Gmbh Method and system for providing a fluid product mailer
CN117126116A (zh) * 2022-05-20 2023-11-28 天津瑞普生物技术股份有限公司 一种异噁唑啉类化合物的衍生物及其应用
CN117122571A (zh) * 2022-05-20 2023-11-28 天津瑞普生物技术股份有限公司 一种抗寄生虫感染的口服药物制剂及其制备方法和应用
KR20240002746A (ko) * 2022-06-30 2024-01-08 주식회사경농 이속사졸린 유도체 화합물 및 이를 포함하는 살충제 조성물
CN115785017B (zh) * 2022-12-06 2023-12-08 海利尔药业集团股份有限公司 一种取代的苯酰胺异噁唑啉衍生物或其作为农药可接受的盐、组合物及其用途

Family Cites Families (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3984564A (en) 1972-06-08 1976-10-05 Sankyo Company Limited Antibiotic substances B-41, their production and their use as insecticides and acaricides
US3950360A (en) 1972-06-08 1976-04-13 Sankyo Company Limited Antibiotic substances
SE434277B (sv) 1976-04-19 1984-07-16 Merck & Co Inc Sett att framstella nya antihelmintiskt verkande foreningar genom odling av streptomyces avermitilis
US4199569A (en) 1977-10-03 1980-04-22 Merck & Co., Inc. Selective hydrogenation products of C-076 compounds and derivatives thereof
ES8800986A1 (es) 1985-07-27 1987-12-01 Pfizer Un procedimiento para la produccion de un nuevo derivado de avermectina
US4916154A (en) 1986-09-12 1990-04-10 American Cyanamid Company 23-Imino derivatives of LL-F28249 compounds
IL98599A (en) 1990-06-28 1995-06-29 Merck & Co Inc Stable salts of "4-deoxy-" 4-epi-methylamino abramectin and insecticides containing them
WO1992000964A1 (en) 1990-07-05 1992-01-23 Nippon Soda Co., Ltd. Amine derivative
GB9205007D0 (en) * 1992-03-07 1992-04-22 Pfizer Ltd Antiparasitic agents
US5399717A (en) 1993-09-29 1995-03-21 Merck & Co., Inc. Glycosidation route to 4"-epi-methylamino-4"-deoxyavermectin B1
US5399582A (en) 1993-11-01 1995-03-21 Merck & Co., Inc. Antiparasitic agents
US5962499A (en) 1995-03-20 1999-10-05 Merck & Co., Inc. Nodulisporic acid derivatives
US5595991A (en) 1995-03-20 1997-01-21 Merck & Co., Inc. Anthelmintic use of nodulisporic acid and analogs thereof
US6221894B1 (en) 1995-03-20 2001-04-24 Merck & Co., Inc. Nodulisporic acid derivatives
EP0819000B1 (en) 1995-03-20 2009-07-08 Merck & Co., Inc. Nodulisporic acid derivatives
FR2750861B1 (fr) 1996-07-11 1998-12-24 Rhone Merieux Procedes d'elimination des parasites, et notamment des ectoparasites de vertebres, notamment de mammiferes et compositions pour la mise en oeuvre de ce procede
US5834260A (en) 1996-08-30 1998-11-10 Merck & Co., Inc. Antiparasitic agents
FR2753377B1 (fr) 1996-09-19 1999-09-24 Rhone Merieux Nouvelle association parasiticide a base de 1-n-phenylpyra- zoles et de lactones macrocycliques endectocides
US20050192319A1 (en) 1996-09-19 2005-09-01 Albert Boeckh Spot-on formulations for combating parasites
FR2761232B1 (fr) 1997-03-26 2000-03-10 Rhone Merieux Procede et moyens d'eradication des puces dans les locaux habites par les petits mammiferes
RU2129430C1 (ru) * 1998-03-17 1999-04-27 Общество С Ограниченной Ответственностью "Вик - Здоровье Животных" Препарат для борьбы с экто- и эндопаразитами животных "сантомектин"
US6265384B1 (en) * 1999-01-26 2001-07-24 Dale L. Pearlman Methods and kits for removing, treating, or preventing lice with driable pediculostatic agents
GB9916052D0 (en) 1999-07-08 1999-09-08 Pfizer Ltd Anthelmintic compositions
RU2149007C1 (ru) * 1999-09-28 2000-05-20 Закрытое акционерное общество "Агроветсервис" Антипаразитарная, антимикробная противовоспалительная мазь пролонгированного действия
AU4509502A (en) * 2000-12-08 2002-07-01 Us Gov Health & Human Serv Compounds for pest control and methods for their use
WO2005030699A1 (ja) 2003-09-30 2005-04-07 Nissan Chemical Industries, Ltd. 置換ベンズアニリド化合物及び有害生物防除剤
GB0402677D0 (en) 2003-11-06 2004-03-10 Novartis Ag Organic compounds
US7361689B2 (en) 2003-12-31 2008-04-22 Schering-Plough Animal Health Corporation Antibacterial 1-(4-mono- and di-halomethylsulphonylphenyl)-2-acylamino-3-fluoroproponals and preparation thereof
KR20060110344A (ko) 2003-12-31 2006-10-24 쉐링-프라우 리미티드 이미다조[1,2-ｂ]피리다진 유도체를 사용하여 동물에서기생충을 방제하는 방법
CN1930136B (zh) 2004-03-05 2012-02-08 日产化学工业株式会社 异*唑啉取代苯甲酰胺化合物及有害生物防除剂
KR20070054691A (ko) 2004-09-23 2007-05-29 쉐링-프라우 리미티드 신규한 트리플루오로메탄설폰아미드 옥심 에테르 유도체를사용하여 동물의 기생충 방제
EP1812385B1 (en) 2004-11-09 2012-07-18 Novartis AG Process for the preparation of enantiomers of amidoacetonitrile compounds from their racemates
DE602005017419D1 (de) 2004-11-19 2009-12-10 Schering Plough Ltd Kontrolle von parasiten bei tieren mittels verwendung von parasitiziden 2-phenyl-3-(1h-pyrrol-2-yl) acrylonitril-derivaten
ES2297332T3 (es) 2004-12-15 2008-05-01 Matsushita Electric Industrial Co., Ltd Apoyo del trafico de tasa de bits garantizada para transmisiones del enlace ascendente.
JP2008545788A (ja) 2005-06-09 2008-12-18 シェーリング−プラウ・リミテッド Ｎ−［（フェニルオキシ）フェニル］−１，１，１−トリフルオロメタンスルホンアミドおよびｎ−［（フェニルスルファニル）フェニル）］−１，１，１−トリフルオロメタンスルホンアミド誘導体による動物中の寄生生物の制御
US20070010465A1 (en) * 2005-07-06 2007-01-11 Branimir Sikic Zosuquidar, daunorubicin, and cytarabine for the treatment of cancer
JP4479917B2 (ja) 2005-09-02 2010-06-09 日産化学工業株式会社 イソキサゾリン置換ベンズアミド化合物及び有害生物防除剤
ES2443690T3 (es) 2005-09-02 2014-02-20 Nissan Chemical Industries, Ltd. Compuesto de benzamida sustituido con isoxazolina y agente controlador de organismos dañinos
WO2007067470A2 (en) 2005-12-06 2007-06-14 Wyeth Benzimidazole non-aqueous compositions
EP1965645A2 (en) 2005-12-14 2008-09-10 E.I. Du Pont De Nemours And Company Isoxazolines for controlling invertebrate pests
TW200803740A (en) 2005-12-16 2008-01-16 Du Pont 5-aryl isoxazolines for controlling invertebrate pests
TWI412322B (zh) 2005-12-30 2013-10-21 Du Pont 控制無脊椎害蟲之異唑啉
DE102006015470A1 (de) 2006-03-31 2007-10-04 Bayer Cropscience Ag Substituierte Enaminocarbonylverbindungen
UA110598C2 (uk) 2006-11-10 2016-01-25 Басф Се Спосіб одержання кристалічної модифікації фіпронілу
JP2008133242A (ja) 2006-11-29 2008-06-12 Nissan Chem Ind Ltd 置換フェニルリチウム化合物の製造方法
MX361762B (es) * 2007-06-27 2018-12-17 Du Pont Metodo de control de plagas en animales.
TWI556741B (zh) 2007-08-17 2016-11-11 英特威特國際股份有限公司 異唑啉組成物及其作為抗寄生蟲藥上的應用
US8044409B2 (en) 2008-08-11 2011-10-25 Taiwan Semiconductor Manufacturing Company, Ltd. III-nitride based semiconductor structure with multiple conductive tunneling layer

Also Published As

Publication number Publication date
EP2190289A2 (en) 2010-06-02
US20240239759A1 (en) 2024-07-18
PL2190289T3 (pl) 2013-09-30
JP5411135B2 (ja) 2014-02-12
KR101725320B1 (ko) 2017-04-10
RU2715051C2 (ru) 2020-02-25
PT2190289E (pt) 2013-08-22
JP2017222692A (ja) 2017-12-21
US20110059988A1 (en) 2011-03-10
CA2694919A1 (en) 2009-02-26
RU2010109901A (ru) 2011-09-27
ES2785104T5 (es) 2023-04-28
RU2481837C2 (ru) 2013-05-20
AU2008290581C1 (en) 2019-07-11
KR20100057066A (ko) 2010-05-28
EP3473101B1 (en) 2021-05-12
CA2694919C (en) 2017-10-17
US20210061775A1 (en) 2021-03-04
JP6014006B2 (ja) 2016-10-25
ES2417157T3 (es) 2013-08-06
US20150111936A1 (en) 2015-04-23
MX351346B (es) 2017-10-11
TWI556741B (zh) 2016-11-11
US20180155301A1 (en) 2018-06-07
NO2016018I1 (no) 2016-10-05
RU2013107094A (ru) 2014-08-27
WO2009024541A2 (en) 2009-02-26
PL2545777T3 (pl) 2020-06-15
JP2016147888A (ja) 2016-08-18
RU2602308C2 (ru) 2016-11-20
JP2010536733A (ja) 2010-12-02
EP3473101A1 (en) 2019-04-24
EP2545777B1 (en) 2020-03-11
RU2016133168A3 (da) 2019-12-12
DK3473101T3 (da) 2021-07-12
BR122020005235B1 (pt) 2023-11-14
CN103705509A (zh) 2014-04-09
KR101792547B1 (ko) 2017-11-02
HK1143037A1 (en) 2010-12-24
EP2545777B2 (en) 2023-01-18
CN101778566A (zh) 2010-07-14
AU2008290581A1 (en) 2009-02-26
US20160332975A1 (en) 2016-11-17
KR20160032278A (ko) 2016-03-23
KR20170041281A (ko) 2017-04-14
AU2008290581B2 (en) 2013-07-25
JP2014097982A (ja) 2014-05-29
PL2545777T5 (pl) 2023-03-27
WO2009024541A3 (en) 2010-04-01
JP6251308B2 (ja) 2017-12-20
ES2785104T3 (es) 2020-10-05
AU2013207639B2 (en) 2016-05-12
EP2190289B1 (en) 2013-05-01
TW200924649A (en) 2009-06-16
BRPI0815227B1 (pt) 2021-02-23
MX2010001907A (es) 2010-04-27
EP2545777A1 (en) 2013-01-16
JP6458095B2 (ja) 2019-01-23
NZ583045A (en) 2012-06-29
ZA201203080B (en) 2012-12-27
RU2016133168A (ru) 2018-02-16
BRPI0815227A2 (pt) 2019-08-06
NZ599797A (en) 2013-08-30

Similar Documents

Publication Publication Date Title
DK2190289T3 (da) Isoxazolinforbindelser og deres anvendelse som antiparasitika
DK2327694T3 (da) Substituerede 4-aminopicolinsyrer og deres anvendelse som herbicider
BRPI0909770A2 (pt) Vacina, e, kit
SE0702657L (sv) Hantel
DK2303872T3 (da) Isoxazolderivater og deres anvendelse som metabotrope glutamatreceptorforstærkere
ATE450271T1 (de) Impfstoff
DK2364293T3 (da) Hidtil ukendte pyrazol-4-N-alkoxycarboxamider som mikrobiocider
CR10571A (es) Vacuna virica recombinante
FR2918570B1 (fr) DIGLYCATION DES AGEs.
DK2222675T3 (da) 5-anilinoimidazopyridiner og fremgangsmåder til deres anvendelse
DK2229572T3 (da) Rekuperator
NO20085030L (no) Pyrrolopyrimidinforbindelser og deres anvendelser
DK2114993T3 (da) Vaccine
BRPI0811578A2 (pt) Tetramatos substituídos por 3-(2-alcóxi-fenila)
DK2086939T3 (da) Pyridiacarboxamid som II-beta-HSDI-inhibitorer
DK2234985T3 (da) 4-(4-cyano-2-thioaryl)-dihydropyrimidinoner og deres anvendelse
DE502008000295D1 (de) Nockenwelle
BRPI0817537A2 (pt) 4-[3-(4-ciclopropanocarbonil-piperazina-i-carboni-,-fl uoro-benzil]-2h-ftalazin-1-ona
BRPI0814314A2 (pt) Microbiocidas
DE602008005502D1 (de) Bohrhammer
DK3338790T3 (da) Oligopeptid-forbindelser og anvendelser deraf
BRPI0821267A2 (pt) Ensaio distintivo
DE102007041169B8 (de) Flugkorbball
NO20073112A (no) Hylseventil
DK2459528T3 (da) 2-(3-alkylthiobenzoyl) cyclohexandion og anvendelsen heraf som herbicider