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DK198390D0 - Heterocykliske forbindelser, deres fremstilling og anvendelse - Google Patents

Heterocykliske forbindelser, deres fremstilling og anvendelse

Info

Publication number
DK198390D0
DK198390D0 DK198390A DK198390A DK198390D0 DK 198390 D0 DK198390 D0 DK 198390D0 DK 198390 A DK198390 A DK 198390A DK 198390 A DK198390 A DK 198390A DK 198390 D0 DK198390 D0 DK 198390D0
Authority
DK
Denmark
Prior art keywords
compounds
preparation
heterocyclic compounds
forebrain
hippocampus
Prior art date
Application number
DK198390A
Other languages
Danish (da)
English (en)
Inventor
Per Sauerberg
Preben H Olesen
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Priority to DK198390A priority Critical patent/DK198390D0/da
Publication of DK198390D0 publication Critical patent/DK198390D0/da
Priority to IL9914591A priority patent/IL99145A/en
Priority to US07/745,033 priority patent/US5328924A/en
Priority to NZ239451A priority patent/NZ239451A/en
Priority to AT91915249T priority patent/ATE159940T1/de
Priority to EP91915249A priority patent/EP0544756B1/en
Priority to JP03513657A priority patent/JP3100158B2/ja
Priority to CA002089767A priority patent/CA2089767C/en
Priority to AU84169/91A priority patent/AU660937B2/en
Priority to ES91915249T priority patent/ES2110997T3/es
Priority to DE69128145T priority patent/DE69128145T2/de
Priority to ZA916579A priority patent/ZA916579B/xx
Priority to PCT/DK1991/000234 priority patent/WO1992003430A1/en
Priority to IE295891A priority patent/IE912958A1/en
Priority to PT98734A priority patent/PT98734B/pt
Priority to NO930599A priority patent/NO302414B1/no
Priority to FI930745A priority patent/FI111640B/fi
Priority to US08/026,708 priority patent/US5376668A/en
Priority to US08/362,031 priority patent/US5571826A/en
Priority to US08/455,300 priority patent/US5559136A/en
Priority to US08/453,605 priority patent/US5658932A/en
Priority to US08/472,351 priority patent/US5534528A/en
Priority to US08/770,484 priority patent/USRE35822E/en
Priority to US08/874,054 priority patent/US5919805A/en
Priority to US09/025,266 priority patent/USRE36375E/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Ophthalmology & Optometry (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Anesthesiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Lubricants (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK198390A 1990-08-21 1990-08-21 Heterocykliske forbindelser, deres fremstilling og anvendelse DK198390D0 (da)

Priority Applications (25)

Application Number Priority Date Filing Date Title
DK198390A DK198390D0 (da) 1990-08-21 1990-08-21 Heterocykliske forbindelser, deres fremstilling og anvendelse
IL9914591A IL99145A (en) 1990-08-21 1991-08-09 History 3- (3-Transformed 1,2,5-thia) or oxa (diazol-4-yl) - 1,2,5,6-tetrahydropyridine, their preparation and pharmaceutical preparations containing them
US07/745,033 US5328924A (en) 1990-08-21 1991-08-14 Heterocyclic compounds and their use
NZ239451A NZ239451A (en) 1990-08-21 1991-08-19 Thiadiazole and oxadiaxole derivatives, preparation and pharmaceutical compositions thereof
PCT/DK1991/000234 WO1992003430A1 (en) 1990-08-21 1991-08-20 Heterocyclic compounds and their preparation and use
DE69128145T DE69128145T2 (de) 1990-08-21 1991-08-20 1,2,5,6-tetrahydro-1-methylpyridine, ihre herstellung und anwendung
EP91915249A EP0544756B1 (en) 1990-08-21 1991-08-20 1,2,5,6-tetrahydro-1-methylpyridines, their preparation and use
JP03513657A JP3100158B2 (ja) 1990-08-21 1991-08-20 複素環化合物及びそれらの製造及び用途
CA002089767A CA2089767C (en) 1990-08-21 1991-08-20 Pyridinyl thiadiazolyl- and oxadiazolyl derivatives
AU84169/91A AU660937B2 (en) 1990-08-21 1991-08-20 Thiadiazole/oxadiazole substituted tetrahydropyridines
ES91915249T ES2110997T3 (es) 1990-08-21 1991-08-20 1,2,5,6-tetrahidro-1-metilpiridinas, su preparacion y uso.
AT91915249T ATE159940T1 (de) 1990-08-21 1991-08-20 1,2,5,6-tetrahydro-1-methylpyridine, ihre herstellung und anwendung
ZA916579A ZA916579B (en) 1990-08-21 1991-08-20 Heterocyclic compounds and their preparation and use
IE295891A IE912958A1 (en) 1990-08-21 1991-08-21 Heterocyclic compounds and their preparation and use
PT98734A PT98734B (pt) 1990-08-21 1991-08-21 Processo de preparacao de compostos 1,2,5,6-tetra-hidropiridina e de composicoes farmaceuticas que os contem
FI930745A FI111640B (fi) 1990-08-21 1993-02-19 Menetelmä uusien terapeuttisesti käyttökelpoisten tetrahydropyridiinijohdannaisten valmistamiseksi
NO930599A NO302414B1 (no) 1990-08-21 1993-02-19 Analogifremgangsmåte for fremstilling av heterocykliske forbindelser
US08/026,708 US5376668A (en) 1990-08-21 1993-03-05 Heterocyclic compounds
US08/362,031 US5571826A (en) 1990-08-21 1994-12-22 Heterocyclic compounds and their preparation and use
US08/455,300 US5559136A (en) 1990-08-21 1995-05-30 Treatment of Alzheimer's disease using azacyclic compounds
US08/453,605 US5658932A (en) 1990-08-21 1995-05-30 Heterocyclic compounds and their preparation and use
US08/472,351 US5534528A (en) 1990-08-21 1995-06-07 Thiadiazolyl tetrhydrpyridines for treating glaucoma
US08/770,484 USRE35822E (en) 1990-08-21 1996-12-20 Heterocyclic compounds
US08/874,054 US5919805A (en) 1990-08-21 1997-06-12 Hetrocyclic compounds and their preparation and use
US09/025,266 USRE36375E (en) 1990-08-21 1998-02-18 Treatment of Alzheimer's disease using azacyclic compounds

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK198390A DK198390D0 (da) 1990-08-21 1990-08-21 Heterocykliske forbindelser, deres fremstilling og anvendelse

Publications (1)

Publication Number Publication Date
DK198390D0 true DK198390D0 (da) 1990-08-21

Family

ID=8109264

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198390A DK198390D0 (da) 1990-08-21 1990-08-21 Heterocykliske forbindelser, deres fremstilling og anvendelse

Country Status (17)

Country Link
US (2) US5328924A (pt)
EP (1) EP0544756B1 (pt)
JP (1) JP3100158B2 (pt)
AT (1) ATE159940T1 (pt)
AU (1) AU660937B2 (pt)
CA (1) CA2089767C (pt)
DE (1) DE69128145T2 (pt)
DK (1) DK198390D0 (pt)
ES (1) ES2110997T3 (pt)
FI (1) FI111640B (pt)
IE (1) IE912958A1 (pt)
IL (1) IL99145A (pt)
NO (1) NO302414B1 (pt)
NZ (1) NZ239451A (pt)
PT (1) PT98734B (pt)
WO (1) WO1992003430A1 (pt)
ZA (1) ZA916579B (pt)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5043345A (en) * 1989-02-22 1991-08-27 Novo Nordisk A/S Piperidine compounds and their preparation and use
DK198490D0 (da) * 1990-08-21 1990-08-21 Novo Nordisk As Heterocykliske forbindelser, deres fremstilling og anvendelse
US5376668A (en) * 1990-08-21 1994-12-27 Novo Nordisk A/S Heterocyclic compounds
US5753683A (en) * 1993-08-19 1998-05-19 Novo Nordisk A/S Antipsychotic method
NZ336597A (en) * 1993-08-19 2001-02-23 Novo Nordisk As Use of oxa- or thia-diazole substituted pyridines for treatment of schizophrenia
IL112024A (en) * 1993-12-21 1999-07-14 Novo Nordisk As Pharmaceutical compositions comprising tetrahydropyridine derivatives substituted with oxadiazole or thiadiazole for treating gastrointestinal motility disorders
US5545638A (en) * 1993-12-21 1996-08-13 Novo Nordisk A/S Method of treating gastrointestinal motility disorders
US5821371A (en) * 1994-10-24 1998-10-13 Eli Lilly And Comany Heterocyclic compounds and their preparation and use
US5998404A (en) 1994-10-24 1999-12-07 Eli Lilly And Company Heterocyclic compounds and their use
US5605908A (en) * 1994-10-24 1997-02-25 Eli Lilly And Company Heterocyclic compounds and their use
US5726193A (en) * 1994-10-31 1998-03-10 Eli Lilly And Company Method for treating anxiety
US5488056A (en) * 1994-10-31 1996-01-30 Eli Lilly And Company Method for treating anxiety
US5574028A (en) * 1994-10-31 1996-11-12 Eli Lilly And Company Method for treating anxiety
US5565475A (en) * 1994-11-08 1996-10-15 Muhlhauser; Mark A. Method of treating urinary bladder dysfunctions with 3-tetrahydropyridine derivatives
AU3203297A (en) * 1996-04-23 1997-11-12 Eli Lilly And Company Heterocyclic compounds
JP2000509046A (ja) * 1996-04-23 2000-07-18 イーライ・リリー・アンド・カンパニー ヘテロサイクリック化合物群
JP2000509044A (ja) * 1996-04-23 2000-07-18 イーライ・リリー・アンド・カンパニー ヘテロサイクリック化合物群
DE69724967D1 (de) * 1996-04-24 2003-10-23 Novo Nordisk As Heterozyklische verbindungen, ihre herstellung und ihre anwendung
US6117890A (en) * 1996-08-01 2000-09-12 Eli Lilly And Company Method for treating bipolar disorder
US6043258A (en) * 1996-08-01 2000-03-28 Eli Lilly And Company Method for treating disruptive behavior disorders with xanomeline
US6090829A (en) * 1996-08-01 2000-07-18 Eli Lilly And Company Method for treating excessive aggression
US6034108A (en) * 1997-07-28 2000-03-07 Eli Lilly And Company Method for treating mental retardation
US6376675B2 (en) * 1999-01-22 2002-04-23 The University Of Toledo Muscarinic receptor agonists
US6490844B1 (en) 2001-06-21 2002-12-10 Emerging Technologies Trust Film wrap packaging apparatus and method
US20110294835A1 (en) 2008-05-15 2011-12-01 The Board Of Trustees Of The University Of Illinois Muscarinic Agonists as Cognitive Enhancers
CA2786716A1 (en) * 2010-01-11 2011-07-14 Mithridion, Inc. Compounds and compositions for cognition-enhancement, methods of making, and methods of treating
WO2012033956A1 (en) 2010-09-08 2012-03-15 Mithridion, Inc. Cognition enhancing compounds and compositions, methods of making, and methods of treating
US9549928B2 (en) 2011-04-29 2017-01-24 The University Of Toledo Muscarinic agonists as enhancers of cognitive flexibility
US11534434B2 (en) 2019-11-15 2022-12-27 Karuna Therapeutics, Inc. Xanomeline derivatives and methods for treating neurological disorders

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ219646A (en) * 1986-03-27 1990-10-26 Merck Sharp & Dohme Oxadiazole derivatives of azacyclics for treating cns disorders
GB8610432D0 (en) * 1986-04-29 1986-06-04 Akzo Nv Amino-thiazole & oxazole derivatives
GB8714789D0 (en) * 1987-06-24 1987-07-29 Lundbeck & Co As H Heterocyclic compounds
GB8717446D0 (en) * 1987-07-23 1987-08-26 Merck Sharp & Dohme Chemical compounds
NZ225999A (en) * 1987-09-10 1992-04-28 Merck Sharp & Dohme Azacyclic- or azabicyclic-substituted thiadiazole derivatives and pharmaceutical compositions
IE63906B1 (en) * 1987-11-13 1995-06-14 Novo Nordisk As Azabicyclic compounds and their preparation and use
EP0322182A3 (en) * 1987-12-22 1992-01-02 Beecham Group Plc Azabicyclic compounds, process for their preparation and pharmaceutical compositions containing them
NZ227841A (en) * 1988-02-12 1991-08-27 Merck Sharp & Dohme Heterocyclic compounds with at least two non-condensed five membered rings and pharmaceutical compositions
DK162892C (da) * 1988-07-04 1992-05-11 Novo Nordisk As 1,2,5,6-tetrahydropyridinforbindelser, deres fremstilling og farmaceutiske praeparater indeholdende disse
US5043345A (en) * 1989-02-22 1991-08-27 Novo Nordisk A/S Piperidine compounds and their preparation and use
DE3905775A1 (de) 1989-02-24 1990-08-30 Kat Tec Ges Fuer Katalysatorte Verfahren und vorrichtung zur reduzierung von schadstoffen eines verbrennungsverfahrens mit oxidations-wabenkatalysatoren und katalysatoren mit entschwefelungseigenschaften und abgasrueckfuehrung
DK198490D0 (da) * 1990-08-21 1990-08-21 Novo Nordisk As Heterocykliske forbindelser, deres fremstilling og anvendelse

Also Published As

Publication number Publication date
US5328924A (en) 1994-07-12
ZA916579B (en) 1992-05-27
EP0544756A1 (en) 1993-06-09
FI930745A (fi) 1993-03-30
ATE159940T1 (de) 1997-11-15
NO302414B1 (no) 1998-03-02
NO930599D0 (no) 1993-02-19
WO1992003430A1 (en) 1992-03-05
NZ239451A (en) 1994-09-27
DE69128145T2 (de) 1998-05-20
IL99145A0 (en) 1992-07-15
AU8416991A (en) 1992-03-17
DE69128145D1 (de) 1997-12-11
PT98734A (pt) 1992-08-31
IE912958A1 (en) 1992-02-26
IL99145A (en) 1996-10-31
CA2089767A1 (en) 1992-02-22
EP0544756B1 (en) 1997-11-05
PT98734B (pt) 1999-01-29
NO930599L (no) 1993-04-19
CA2089767C (en) 2005-05-03
US5534528A (en) 1996-07-09
JPH06501682A (ja) 1994-02-24
JP3100158B2 (ja) 2000-10-16
AU660937B2 (en) 1995-07-13
ES2110997T3 (es) 1998-03-01
FI111640B (fi) 2003-08-29
FI930745A0 (fi) 1993-02-19

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Legal Events

Date Code Title Description
AHS Application shelved for other reasons than non-payment