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DK1511761T3 - Fremgangsmåde til fremstilling af cykliske peptider - Google Patents

Fremgangsmåde til fremstilling af cykliske peptider

Info

Publication number
DK1511761T3
DK1511761T3 DK04759123T DK04759123T DK1511761T3 DK 1511761 T3 DK1511761 T3 DK 1511761T3 DK 04759123 T DK04759123 T DK 04759123T DK 04759123 T DK04759123 T DK 04759123T DK 1511761 T3 DK1511761 T3 DK 1511761T3
Authority
DK
Denmark
Prior art keywords
cyclic peptides
producing cyclic
polypeptides
producing
peptides
Prior art date
Application number
DK04759123T
Other languages
English (en)
Inventor
Avi Tovi
Chaim Eidelman
Shimon Shushan
Shai Elster
Hagi Alon
Original Assignee
Novetide Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=33299783&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1511761(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novetide Ltd filed Critical Novetide Ltd
Application granted granted Critical
Publication of DK1511761T3 publication Critical patent/DK1511761T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/585—Calcitonins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C07K1/061—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
    • C07K1/067—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups for sulfur-containing functions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C07K14/6555—Somatostatins at least 1 amino acid in D-form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/75—Fibrinogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/16—Oxytocins; Vasopressins; Related peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK04759123T 2003-04-07 2004-04-05 Fremgangsmåde til fremstilling af cykliske peptider DK1511761T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US46122203P 2003-04-07 2003-04-07

Publications (1)

Publication Number Publication Date
DK1511761T3 true DK1511761T3 (da) 2006-11-27

Family

ID=33299783

Family Applications (1)

Application Number Title Priority Date Filing Date
DK04759123T DK1511761T3 (da) 2003-04-07 2004-04-05 Fremgangsmåde til fremstilling af cykliske peptider

Country Status (9)

Country Link
US (3) US20040249121A1 (da)
EP (1) EP1511761B1 (da)
AT (1) ATE334998T1 (da)
DE (2) DE04759123T1 (da)
DK (1) DK1511761T3 (da)
ES (1) ES2237356T3 (da)
PT (1) PT1511761E (da)
TW (1) TW200505939A (da)
WO (1) WO2004092202A1 (da)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1735345E (pt) * 2004-04-08 2009-09-11 Millennium Pharm Inc Processos para a preparação de eptifibatida e compostos intermediários pertinentes
US20080182781A1 (en) * 2004-06-14 2008-07-31 Saksena Divya L Process for the Preparation of Peptides
US7897724B2 (en) * 2004-10-10 2011-03-01 Usv, Ltd. Solid phase Fmoc chemistry process to prepare peptides
DE602005021614D1 (de) * 2004-10-04 2010-07-15 Novetide Ltd Gegenionenaustauschverfahren für peptide
ES2339791T3 (es) * 2004-10-19 2010-05-25 Lonza Ag Ciclizacion de peptidos sobre resina.
US8226949B2 (en) * 2006-06-23 2012-07-24 Aegis Therapeutics Llc Stabilizing alkylglycoside compositions and methods thereof
WO2008109079A2 (en) * 2007-03-01 2008-09-12 Novetide, Ltd. High purity peptides
CN101372505B (zh) * 2007-08-22 2011-03-30 深圳翰宇药业股份有限公司 一种制备醋酸去氨加压素的方法
WO2009150657A1 (en) * 2008-06-09 2009-12-17 Natco Pharma Limited Improved process for preparation of eptifibatide by fmoc solid phase synthesis
WO2010089757A2 (en) 2008-11-07 2010-08-12 Usv Limited An improved process for synthesis of cyclic octapeptide
US20120094910A1 (en) 2009-04-06 2012-04-19 Ananda Kuppanna Improved process for the preparation of desmopressin or its pharmaceutically acceptable salts
WO2011011342A1 (en) * 2009-07-20 2011-01-27 Mallinckrodt Inc. Synthesis of desmopressin
US20120178900A1 (en) * 2009-08-11 2012-07-12 Biocon Limited Chromatographic processes and purified compounds thereof
EP3056510B1 (en) 2010-03-03 2018-10-03 The University Of British Columbia Oligomer-specific amyloid beta epitope and antibodies
WO2011156686A2 (en) * 2010-06-11 2011-12-15 The Regents Of The University Of Colorado, A Body Corporate Method for synthesizing a cyclic multivalent peptide using a thiol-mediated reaction
US9388212B2 (en) 2013-02-21 2016-07-12 Chemical & Biopharmaceutical Laboratories Of Patras S.A. Solid phase peptide synthesis via side chain attachment
KR102159138B1 (ko) * 2013-02-21 2020-09-24 케미컬 앤드 바이오파마슈티컬 라보라토리즈 오브 파트라스 에스.에이. 측쇄 부착을 통한 고상 펩타이드 합성 방법
CN104761619A (zh) * 2015-01-06 2015-07-08 苏州天马医药集团天吉生物制药有限公司 醋酸去氨加压素的固相制备工艺
CN108350052A (zh) 2015-11-09 2018-07-31 英属哥伦比亚大学 淀粉样蛋白β中间区域中的表位及其构象选择性抗体
WO2019246201A1 (en) 2018-06-20 2019-12-26 Axcella Health Inc. Methods of manufacturing amino acid compositions
CN110016070B (zh) * 2019-05-06 2021-07-20 上海上药第一生化药业有限公司 一种加压素[+Gly]杂质的精制方法
CN109942686B (zh) * 2019-05-06 2021-06-25 上海上药第一生化药业有限公司 一种加压素乙酰化杂质的精制方法
CN112521482B (zh) * 2019-08-28 2023-09-12 深圳翰宇药业股份有限公司 一种固液结合合成奈西立肽的制备方法
CN114437233A (zh) * 2020-11-06 2022-05-06 湖北健翔生物制药有限公司 一种多肽二聚体的定向合成方法
CN115057913A (zh) * 2022-06-20 2022-09-16 遵义医科大学珠海校区 一种短杆菌肽s类似物gs-5的制备方法
WO2024112250A1 (en) * 2022-11-23 2024-05-30 Polypeptide Laboratories Holding (Ppl) Ab Method of preparing vasopressin
CN116023441A (zh) * 2022-12-29 2023-04-28 江苏诺泰澳赛诺生物制药股份有限公司 一种制备纯化去氨加压素亚砜杂质的方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LU78191A1 (de) * 1977-09-28 1979-05-25 Ciba Geigy Ag Verfahren zur herstellung von neuen cyclopeptiden
DE2923787A1 (de) * 1979-06-12 1980-12-18 Max Planck Gesellschaft Verfahren zur selektiven bildung von disulfidbruecken in polypeptiden und die dabei erhaltenen produkte als wirkstoffe enthaltende arzneimittel
US4235886A (en) * 1979-10-31 1980-11-25 Merck & Co., Inc. Cyclic hexapeptide somatostatin analogs
US4310518A (en) * 1979-10-31 1982-01-12 Merck & Co., Inc. Cyclic hexapeptide somatostatin analogs
CY1327A (en) * 1979-11-27 1986-06-27 Sandoz Ag Novel polypeptides,processes for their production,pharmaceutical compositions comprising said polypeptides and their use
US5770564A (en) * 1989-06-16 1998-06-23 Cor Therapeutics, Inc. Platelet aggregation inhibitors
US5500413A (en) * 1993-06-29 1996-03-19 Ferring Ab Process for manufacture of 1-deamino-8-D-arginine vasopressin
WO1999014238A1 (en) * 1997-09-18 1999-03-25 Hyundai Pharm. Ind. Co., Ltd. Process for the preparation of calcitonin
US5889146A (en) * 1997-11-26 1999-03-30 Institute Of Nuclear Energy Research Method for synthesis of bifunctional chelating agents-peptides
ES2144357B1 (es) * 1998-01-29 2000-12-16 Lipotec Sa Procedimiento para la obtencion del analogo de somatostatina octreotide.
DE60026708T2 (de) * 1999-07-19 2006-12-14 Amersham Health As Verfahren zur entschützung von geschützten thiolen

Also Published As

Publication number Publication date
TW200505939A (en) 2005-02-16
EP1511761B1 (en) 2006-08-02
US20040249121A1 (en) 2004-12-09
ES2237356T3 (es) 2007-04-01
DE602004001727D1 (de) 2006-09-14
PT1511761E (pt) 2006-11-30
ES2237356T1 (es) 2005-08-01
US20100240865A1 (en) 2010-09-23
WO2004092202A1 (en) 2004-10-28
EP1511761A1 (en) 2005-03-09
DE04759123T1 (de) 2005-08-18
US20100137559A1 (en) 2010-06-03
ATE334998T1 (de) 2006-08-15
DE602004001727T2 (de) 2007-08-02

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