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DK0666868T3 - Anvendelse af anti-VEGF-antistoffer til behandling af cancer - Google Patents

Anvendelse af anti-VEGF-antistoffer til behandling af cancer

Info

Publication number
DK0666868T3
DK0666868T3 DK92923512T DK92923512T DK0666868T3 DK 0666868 T3 DK0666868 T3 DK 0666868T3 DK 92923512 T DK92923512 T DK 92923512T DK 92923512 T DK92923512 T DK 92923512T DK 0666868 T3 DK0666868 T3 DK 0666868T3
Authority
DK
Denmark
Prior art keywords
hvegf
antagonist
treat cancer
hvegfr
tumour
Prior art date
Application number
DK92923512T
Other languages
English (en)
Other versions
DK0666868T4 (da
Inventor
Kyung Jin Kim
Napoleone Ferrara
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44652081&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0666868(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of DK0666868T3 publication Critical patent/DK0666868T3/da
Application granted granted Critical
Publication of DK0666868T4 publication Critical patent/DK0666868T4/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Mycology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK92923512T 1992-10-28 1992-10-28 Anvendelse af anti-VEGF-antistoffer til behandling af cancer DK0666868T4 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1992/009218 WO1994010202A1 (en) 1992-10-28 1992-10-28 Vascular endothelial cell growth factor antagonists

Publications (2)

Publication Number Publication Date
DK0666868T3 true DK0666868T3 (da) 2002-07-29
DK0666868T4 DK0666868T4 (da) 2006-09-18

Family

ID=44652081

Family Applications (4)

Application Number Title Priority Date Filing Date
DK08010320.3T DK1975181T3 (da) 1992-10-28 1992-10-28 Anvendelse af vaskulære endothelcelle-vækstfaktor-antagonister
DK02006351T DK1238986T3 (da) 1992-10-28 1992-10-28 Anvendelse af antagonister mod vaskulær endotelcellevækstfaktor
DK01119430T DK1167384T3 (da) 1992-10-28 1992-10-28 Vaskular endotheliel cellevækstfaktor antagonister
DK92923512T DK0666868T4 (da) 1992-10-28 1992-10-28 Anvendelse af anti-VEGF-antistoffer til behandling af cancer

Family Applications Before (3)

Application Number Title Priority Date Filing Date
DK08010320.3T DK1975181T3 (da) 1992-10-28 1992-10-28 Anvendelse af vaskulære endothelcelle-vækstfaktor-antagonister
DK02006351T DK1238986T3 (da) 1992-10-28 1992-10-28 Anvendelse af antagonister mod vaskulær endotelcellevækstfaktor
DK01119430T DK1167384T3 (da) 1992-10-28 1992-10-28 Vaskular endotheliel cellevækstfaktor antagonister

Country Status (18)

Country Link
EP (4) EP1167384B1 (da)
JP (1) JP3398382B2 (da)
KR (1) KR100335584B1 (da)
AT (4) ATE498632T1 (da)
AU (1) AU687727B2 (da)
BG (1) BG99605A (da)
BR (1) BR9207175A (da)
CA (1) CA2145985C (da)
CZ (1) CZ291047B6 (da)
DE (3) DE69233803D1 (da)
DK (4) DK1975181T3 (da)
ES (4) ES2360641T3 (da)
FI (1) FI951987A0 (da)
HU (2) HU225646B1 (da)
NO (1) NO321825B1 (da)
RO (1) RO119721B1 (da)
SK (1) SK285035B6 (da)
WO (1) WO1994010202A1 (da)

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