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DK0448930T3 - Stabile præparater til parenteral administration og fremgangsmåde til fremstilling deraf - Google Patents

Stabile præparater til parenteral administration og fremgangsmåde til fremstilling deraf

Info

Publication number
DK0448930T3
DK0448930T3 DK91100650.0T DK91100650T DK0448930T3 DK 0448930 T3 DK0448930 T3 DK 0448930T3 DK 91100650 T DK91100650 T DK 91100650T DK 0448930 T3 DK0448930 T3 DK 0448930T3
Authority
DK
Denmark
Prior art keywords
preparation
methods
parenteral administration
stable preparations
preparations
Prior art date
Application number
DK91100650.0T
Other languages
Danish (da)
English (en)
Inventor
William Steber
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Application granted granted Critical
Publication of DK0448930T3 publication Critical patent/DK0448930T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/27—Growth hormone [GH], i.e. somatotropin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
DK91100650.0T 1990-03-30 1991-01-21 Stabile præparater til parenteral administration og fremgangsmåde til fremstilling deraf DK0448930T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/502,382 US5213810A (en) 1990-03-30 1990-03-30 Stable compositions for parenteral administration and method of making same

Publications (1)

Publication Number Publication Date
DK0448930T3 true DK0448930T3 (da) 1994-06-20

Family

ID=23997559

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91100650.0T DK0448930T3 (da) 1990-03-30 1991-01-21 Stabile præparater til parenteral administration og fremgangsmåde til fremstilling deraf

Country Status (29)

Country Link
US (1) US5213810A (ko)
EP (1) EP0448930B1 (ko)
JP (1) JP2966564B2 (ko)
KR (1) KR0159778B1 (ko)
CN (1) CN1063941C (ko)
AR (1) AR248085A1 (ko)
AT (1) ATE106240T1 (ko)
AU (1) AU641994B2 (ko)
BG (1) BG60850B1 (ko)
CA (1) CA2039491C (ko)
CZ (1) CZ283053B6 (ko)
DE (1) DE69102176T2 (ko)
DK (1) DK0448930T3 (ko)
ES (1) ES2054380T3 (ko)
FI (1) FI101676B (ko)
HK (1) HK1000004A1 (ko)
HU (1) HU219584B (ko)
IE (1) IE65970B1 (ko)
IL (1) IL97145A (ko)
MX (1) MX172602B (ko)
NO (1) NO300717B1 (ko)
NZ (1) NZ237509A (ko)
PL (1) PL167692B1 (ko)
PT (1) PT97160B (ko)
RO (1) RO106191B1 (ko)
RU (1) RU2011377C1 (ko)
SK (1) SK279461B6 (ko)
YU (1) YU47650B (ko)
ZA (1) ZA912398B (ko)

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US5683720A (en) * 1994-10-28 1997-11-04 Fuisz Technologies Ltd. Liquiflash particles and method of making same
US6083430A (en) * 1994-10-28 2000-07-04 Fuisz Technologies Ltd. Method of preparing a dosage unit by direct tableting and product therefrom
DE69828635T2 (de) 1997-09-19 2005-06-16 Shire Laboratories, Inc. Feste lösungskügelchen
AU2002300572B2 (en) * 1997-09-19 2004-11-25 Shire Laboratories, Inc. Solid Solution Beadlet
US6117452A (en) * 1998-08-12 2000-09-12 Fuisz Technologies Ltd. Fatty ester combinations
BR0010354A (pt) * 1999-05-07 2002-03-05 Pharmasol Gmbh Partìculas de lipìdeo à base em misturas de lipìdeos lìquidos e sólidos e método para a sua produção
US8663692B1 (en) * 1999-05-07 2014-03-04 Pharmasol Gmbh Lipid particles on the basis of mixtures of liquid and solid lipids and method for producing same
MXPA01012659A (es) * 1999-06-07 2003-09-04 Altana Pharma Ag Nueva forma de administracion y preparacion que comprende un compuesto activo labil acido.
WO2001080831A2 (en) 2000-04-27 2001-11-01 Verion Inc. Zero order release and temperature-controlled microcapsules and process for the preparation thereof
AU7302801A (en) * 2000-06-26 2002-01-08 Omegatech Inc Improved methods of incorporating polyunsaturated fatty acids in milk
CA2423484A1 (en) 2000-09-27 2002-04-04 Verion Inc. Instant water dissolvable encapsulate and process
PT1197207E (pt) * 2000-10-10 2008-07-01 Wyeth Corp Composições estáveis para administração parentérica
FR2852843B1 (fr) 2003-03-24 2008-05-23 Karim Ioualalen Systeme galenique permettant le masquage du gout
RU2006119453A (ru) * 2003-12-04 2007-12-20 Пфайзер Продактс Инк. (Us) Получение посредством основанных на применении жидкостей способов лекарственные формы азитромицина с большим количеством частиц
PT1691787E (pt) * 2003-12-04 2008-09-02 Pfizer Prod Inc Método de formação de multipartículas farmacêuticas
KR20080064209A (ko) * 2003-12-04 2008-07-08 화이자 프로덕츠 인코포레이티드 바람직하게는 폴록사머와 글리세라이드를 함유하는다미립자 아지트로마이신 조성물의 제조를 위해 압출기를사용하는 분무응결 방법
WO2005053652A1 (en) 2003-12-04 2005-06-16 Pfizer Products Inc. Multiparticulate crystalline drug compositions containing a poloxamer and a glyceride
BRPI0416534A (pt) * 2003-12-04 2007-01-09 Pfizer Prod Inc composições multiparticuladas com estabilidade melhorada
EP1689368B1 (en) * 2003-12-04 2016-09-28 Bend Research, Inc Spray-congeal process using an extruder for preparing multiparticulate crystalline drug compositions
US6984403B2 (en) * 2003-12-04 2006-01-10 Pfizer Inc. Azithromycin dosage forms with reduced side effects
WO2005053639A2 (en) * 2003-12-04 2005-06-16 Pfizer Products Inc. Controlled release multiparticulates formed with dissolution enhancers
US11246913B2 (en) 2005-02-03 2022-02-15 Intarcia Therapeutics, Inc. Suspension formulation comprising an insulinotropic peptide
US8299025B2 (en) 2005-02-03 2012-10-30 Intarcia Therapeutics, Inc. Suspension formulations of insulinotropic peptides and uses thereof
US8221809B2 (en) * 2006-06-22 2012-07-17 Martek Biosciences Corporation Encapsulated labile compound compositions and methods of making the same
JP5048773B2 (ja) 2006-08-09 2012-10-17 インターシア セラピューティクス，インコーポレイティド 浸透圧式デリバリーシステム及びピストンアセンブリー
WO2009102467A2 (en) 2008-02-13 2009-08-20 Intarcia Therapeutics, Inc. Devices, formulations, and methods for delivery of multiple beneficial agents
CN104248623B (zh) 2008-09-04 2020-04-03 安米林药品有限责任公司 使用非水性载体的持续释放制剂
JP5494957B2 (ja) 2009-06-11 2014-05-21 株式会社リコー 静電荷像現像用トナー、現像剤、画像形成方法及び画像形成装置
NO2462246T3 (ko) 2009-09-28 2018-02-03
US20120208755A1 (en) 2011-02-16 2012-08-16 Intarcia Therapeutics, Inc. Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers
US9364549B2 (en) 2011-11-30 2016-06-14 Andreas Voigt Hydrophobic drug-delivery material, method for manufacturing thereof and methods for delivery of a drug-delivery composition
US20160151286A1 (en) * 2013-05-29 2016-06-02 Therakine Biodelivery Gmbh Hydrophilic Microparticles, Drug-Delivery Material, Method For Manufacturing Thereof And Methods For Delivery of A Drug-Delivery Composition
US9889085B1 (en) 2014-09-30 2018-02-13 Intarcia Therapeutics, Inc. Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c
KR102650751B1 (ko) 2015-06-03 2024-03-22 인타르시아 세라퓨틱스 인코포레이티드 임플란트 배치 및 제거 시스템들
EP3458084B1 (en) 2016-05-16 2020-04-01 Intarcia Therapeutics, Inc Glucagon-receptor selective polypeptides and methods of use thereof
USD840030S1 (en) 2016-06-02 2019-02-05 Intarcia Therapeutics, Inc. Implant placement guide
USD860451S1 (en) 2016-06-02 2019-09-17 Intarcia Therapeutics, Inc. Implant removal tool
AU2018206539A1 (en) 2017-01-03 2019-07-18 Intarcia Therapeutics, Inc. Methods comprising continuous administration of a GLP-1 receptor agonist and co-administration of a drug
KR20220013540A (ko) * 2019-02-21 2022-02-04 크로마덱스 아이엔씨. 니코틴아미드 리보사이드, 니코틴산 리보사이드, 환원 니코티닐 리보사이드 화합물, 및 니코티닐 리보사이드 화합물 유도체의 제형에서의 용도

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US3147187A (en) * 1962-09-10 1964-09-01 Don Hall Lab Sustained release pharmaceutical
CH637297A5 (fr) * 1978-12-05 1983-07-29 Nestle Sa Microbille comprenant un microorganisme et son procede de fabrication.
JPS56140915A (en) * 1980-04-07 1981-11-04 Yamanouchi Pharmaceut Co Ltd Pharmaceutical preparation for solid drug
US4331654A (en) * 1980-06-13 1982-05-25 Eli Lilly And Company Magnetically-localizable, biodegradable lipid microspheres
DE3024416C2 (de) * 1980-06-28 1982-04-15 Gödecke AG, 1000 Berlin Verfahren zur Herstellung von Arzneimitteln mit retardierter Wirkstoff-Freisetzung
US4666839A (en) * 1982-12-01 1987-05-19 Amgen Methods and materials for obtaining microbial expression of polypeptides including bovine prolactin
US4452775A (en) * 1982-12-03 1984-06-05 Syntex (U.S.A.) Inc. Cholesterol matrix delivery system for sustained release of macromolecules
US4603044A (en) * 1983-01-06 1986-07-29 Technology Unlimited, Inc. Hepatocyte Directed Vesicle delivery system
US4568559A (en) * 1984-02-06 1986-02-04 Biotek, Inc. Composite core coated microparticles and process of preparing same
US4568536A (en) * 1985-02-08 1986-02-04 Ethicon, Inc. Controlled release of pharmacologically active agents from an absorbable biologically compatible putty-like composition
US4755387A (en) * 1985-03-21 1988-07-05 The Procter & Gamble Company Therapeutic particles
DE3527356A1 (de) * 1985-07-31 1987-02-05 Degussa Verfahren zur verbesserung der fruchtbarkeit von haustieren
SE462894B (sv) * 1985-10-28 1990-09-17 Biogram Ab Mikrokapslar, foerfarande foer framstaellning daerav samt anvaendning
US4837381A (en) * 1986-08-11 1989-06-06 American Cyanamid Company Compositions for parenteral administration and their use
US4911928A (en) * 1987-03-13 1990-03-27 Micro-Pak, Inc. Paucilamellar lipid vesicles

Also Published As

Publication number Publication date
NZ237509A (en) 1993-04-28
BG93923A (bg) 1993-12-24
CZ283053B6 (cs) 1997-12-17
NO911228D0 (no) 1991-03-26
HU911054D0 (en) 1991-10-28
ZA912398B (en) 1992-01-29
HK1000004A1 (en) 1997-10-03
EP0448930A1 (en) 1991-10-02
MX172602B (es) 1993-01-03
CN1063941C (zh) 2001-04-04
KR910016322A (ko) 1991-11-05
FI101676B1 (fi) 1998-08-14
PT97160A (pt) 1991-11-29
IE911041A1 (en) 1991-10-09
FI911531A0 (fi) 1991-03-28
YU57091A (sh) 1994-01-20
CN1055293A (zh) 1991-10-16
CA2039491C (en) 2001-09-04
KR0159778B1 (ko) 1998-12-01
IL97145A0 (en) 1992-05-25
YU47650B (sh) 1995-12-04
FI911531A (fi) 1991-10-01
AU7397291A (en) 1991-10-03
NO300717B1 (no) 1997-07-14
RO106191B1 (ro) 1993-03-31
ES2054380T3 (es) 1994-08-01
PL167692B1 (en) 1995-10-31
PT97160B (pt) 1998-07-31
PL289657A1 (en) 1992-01-13
NO911228L (no) 1991-10-01
BG60850B1 (bg) 1996-05-31
IE65970B1 (en) 1995-11-29
FI101676B (fi) 1998-08-14
CA2039491A1 (en) 1991-10-01
HU219584B (hu) 2001-05-28
DE69102176T2 (de) 1995-01-05
IL97145A (en) 1996-06-18
HUT59834A (en) 1992-07-28
ATE106240T1 (de) 1994-06-15
AU641994B2 (en) 1993-10-07
AR248085A1 (es) 1995-06-30
RU2011377C1 (ru) 1994-04-30
US5213810A (en) 1993-05-25
SK279461B6 (sk) 1998-11-04
EP0448930B1 (en) 1994-06-01
DE69102176D1 (de) 1994-07-07
JPH04221319A (ja) 1992-08-11
JP2966564B2 (ja) 1999-10-25

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