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DD265141A5 - Verfahren zur herstellung einer antiallergisch und entzuendungshemmende wirkende verbindung - Google Patents

Verfahren zur herstellung einer antiallergisch und entzuendungshemmende wirkende verbindung Download PDF

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Publication number
DD265141A5
DD265141A5 DD87303578A DD30357887A DD265141A5 DD 265141 A5 DD265141 A5 DD 265141A5 DD 87303578 A DD87303578 A DD 87303578A DD 30357887 A DD30357887 A DD 30357887A DD 265141 A5 DD265141 A5 DD 265141A5
Authority
DD
German Democratic Republic
Prior art keywords
compounds
hydrogen
nmr
methyl
formula
Prior art date
Application number
DD87303578A
Other languages
German (de)
English (en)
Inventor
Kitaura Yoshihiko
Ito Fumitaka
Rodney W Stevens
Asai Nobuko
Original Assignee
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Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ������@������������k�� filed Critical ������@������������k��
Publication of DD265141A5 publication Critical patent/DD265141A5/de

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54Benzoxazoles; Hydrogenated benzoxazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54Benzoxazoles; Hydrogenated benzoxazoles
    • C07D263/58Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32Oxygen atoms
    • C07D209/34Oxygen atoms in position 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/26Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62Benzothiazoles
    • C07D277/68Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Fats And Perfumes (AREA)
  • External Artificial Organs (AREA)
  • Indole Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Non-Silver Salt Photosensitive Materials And Non-Silver Salt Photography (AREA)
  • Hydrogenated Pyridines (AREA)
DD87303578A 1986-06-09 1987-06-05 Verfahren zur herstellung einer antiallergisch und entzuendungshemmende wirkende verbindung DD265141A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP13347086 1986-06-09

Publications (1)

Publication Number Publication Date
DD265141A5 true DD265141A5 (de) 1989-02-22

Family

ID=15105525

Family Applications (1)

Application Number Title Priority Date Filing Date
DD87303578A DD265141A5 (de) 1986-06-09 1987-06-05 Verfahren zur herstellung einer antiallergisch und entzuendungshemmende wirkende verbindung

Country Status (21)

Country Link
EP (1) EP0249407B1 (xx)
JP (1) JPH0623199B2 (xx)
KR (1) KR900000552B1 (xx)
CN (1) CN1015334B (xx)
AT (1) ATE60596T1 (xx)
AU (1) AU586337B2 (xx)
CA (1) CA1305151C (xx)
DD (1) DD265141A5 (xx)
DE (1) DE3767778D1 (xx)
DK (1) DK288287A (xx)
ES (1) ES2031892T3 (xx)
FI (1) FI87924C (xx)
GR (1) GR3001584T3 (xx)
HU (1) HU198451B (xx)
IE (1) IE60015B1 (xx)
NO (1) NO168246C (xx)
PL (1) PL150631B1 (xx)
PT (1) PT85035B (xx)
SU (1) SU1757464A3 (xx)
YU (1) YU45423B (xx)
ZA (1) ZA874046B (xx)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4720297A (en) * 1985-09-27 1988-01-19 Sumitomo Chemical Company, Limited Benzothiazolones, and their production and use as herbicides
JPH0283376A (ja) * 1988-09-19 1990-03-23 Pfizer Pharmaceut Co Ltd ベンゾオキサゾロン誘導体および抗アレルギー又は抗炎症組成物
IL93473A0 (en) * 1989-02-28 1990-11-29 Pfizer Antiinflammatory benzoxazolones
JPH0678327B2 (ja) * 1989-07-20 1994-10-05 ファイザー製薬株式会社 4,5,6,7,―四置換ベンゾオキサゾロン類
JPH0729998B2 (ja) * 1990-01-22 1995-04-05 ファイザー製薬株式会社 新規ベンゾキノン化合物およびその組成物
AU6966696A (en) * 1995-10-05 1997-04-28 Warner-Lambert Company Method for treating and preventing inflammation and atherosclerosis
US6001866A (en) * 1995-10-05 1999-12-14 Warner-Lambert Company Method for treating and preventing inflammation and atherosclerosis
US5972980A (en) * 1995-10-05 1999-10-26 Warner-Lambert Company Method for treating and preventing inflammation and atherosclerosis
WO2002070478A1 (en) 2001-03-06 2002-09-12 Astrazeneca Ab Indolone derivatives having vascular-damaging activity
DE10210779A1 (de) * 2002-03-12 2003-10-09 Merck Patent Gmbh Cyclische Amide
TW200508197A (en) * 2003-03-31 2005-03-01 Ucb Sa Indolone-acetamide derivatives, processes for preparing them and their uses
US7270805B1 (en) * 2006-03-30 2007-09-18 Conopco, Inc. Skin lightening agents, compositions and methods
WO2010090680A1 (en) * 2008-12-15 2010-08-12 Wyeth Llc Substituted oxindole cb2 agonists
JP5964965B2 (ja) * 2011-08-18 2016-08-03 ドクター レディズ ラボラトリーズ リミテッド コレステリルエステル転送タンパク質(cetp)インヒビターとしての置換複素環式アミン化合物
DK2852581T3 (en) 2012-05-21 2016-08-01 Dr August Wolff Gmbh & Co Kg Arzneimittel NOVEL 1,3-benzoxazol-2 (3H) -ONES and Their Use as médicaments AND COSMETICS
EP3932395A1 (en) * 2020-07-03 2022-01-05 Dr. August Wolff GmbH & Co. KG Arzneimittel Stable emulsion containing an active pharmaceutical ingredient based on n(3-methyl-2-oxo-2,3-dihydrobenzo[d]oxazol-5-yl)dodecanamide, production and use

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5663972A (en) * 1979-10-30 1981-05-30 Tetsujirou Masuko Preparation of novel benzothiazolone derivative containing novel heterocyclic quaternary salt
DE3017977A1 (de) * 1980-05-10 1981-11-19 Dr. Karl Thomae Gmbh, 7950 Biberach Neue substituierte 2(3h)-benzothiazolone
DE3042481A1 (de) * 1980-11-11 1982-06-16 A. Nattermann & Cie GmbH, 5000 Köln (omega)-(2-oxo-benzazolinyl)-alkansaeure-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
GB8325370D0 (en) * 1983-09-22 1983-10-26 Fujisawa Pharmaceutical Co Benzoxazoline and benzothiazoline derivatives
US4569942A (en) * 1984-05-04 1986-02-11 Pfizer Inc. N,3-Disubstituted 2-oxindole-1-carboxamides as analgesic and antiinflammatory agents
US4690943A (en) * 1984-09-19 1987-09-01 Pfizer Inc. Analgesic and antiinflammatory 1,3-diacyl-2-oxindole compounds

Also Published As

Publication number Publication date
HU198451B (en) 1989-10-30
NO872382L (no) 1987-12-10
AU586337B2 (en) 1989-07-06
PT85035B (pt) 1990-03-08
JPS63107958A (ja) 1988-05-12
CA1305151C (en) 1992-07-14
ATE60596T1 (de) 1991-02-15
YU45423B (en) 1992-05-28
GR3001584T3 (en) 1992-11-23
NO168246C (no) 1992-01-29
PT85035A (en) 1987-07-01
HUT48209A (en) 1989-05-29
EP0249407B1 (en) 1991-01-30
SU1757464A3 (ru) 1992-08-23
FI87924C (fi) 1993-03-10
CN87104099A (zh) 1988-02-10
NO872382D0 (no) 1987-06-05
FI872555A (fi) 1987-12-10
ES2031892T3 (es) 1996-07-16
AU7387887A (en) 1987-12-10
YU104987A (en) 1988-08-31
NO168246B (no) 1991-10-21
EP0249407A2 (en) 1987-12-16
PL266132A1 (en) 1988-06-23
FI872555A0 (fi) 1987-06-08
KR880000413A (ko) 1988-03-25
ZA874046B (en) 1989-01-25
PL150631B1 (en) 1990-06-30
FI87924B (fi) 1992-11-30
JPH0623199B2 (ja) 1994-03-30
DE3767778D1 (de) 1991-03-07
KR900000552B1 (ko) 1990-01-31
CN1015334B (zh) 1992-01-29
IE60015B1 (en) 1994-05-18
IE871505L (en) 1987-12-09
EP0249407A3 (en) 1988-10-19
DK288287D0 (da) 1987-06-04
DK288287A (da) 1987-12-10

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Legal Events

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ENJ Ceased due to non-payment of renewal fee