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CN101791283A - Cosmetic capable of eliminating striae gravidarum and scars - Google Patents

Cosmetic capable of eliminating striae gravidarum and scars Download PDF

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Publication number
CN101791283A
CN101791283A CN201010106552A CN201010106552A CN101791283A CN 101791283 A CN101791283 A CN 101791283A CN 201010106552 A CN201010106552 A CN 201010106552A CN 201010106552 A CN201010106552 A CN 201010106552A CN 101791283 A CN101791283 A CN 101791283A
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skin
parts
striae gravidarum
cicatrix
repair
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CN101791283B (en
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张德文
徐凤伟
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Abstract

The invention discloses a cosmetic capable of eliminating striae gravidarum and scars, which is prepared by the following components: 1.8-2.3 parts of 1,3-butanediol, 1.6-2.4 parts of nicotinamide, 0.08-0.13 part of allantoin, 0.05-0.6 part of preservative, 0.8-1.3 parts of cell growth factor, 0.6-1.5 parts of VB2, 0.85-1.35 parts of asiaticoside, 2.0-3.0 parts of cocoa oil, 2.5-3.5 parts of collagen, etc. The cosmetic can ensure skin to be moist and soft, promote cell growth, quicken wound healing, promote wound surfaces of skin and mucosa to heal, shrink scar, quicken the repair of injured epidermic cells, and strengthen regeneration ability of epidermic cells, thus enabling skin to be full, keeping skin elasticity and strengthening skin physiological function. The cosmetic is safe and reliable without any toxic or side effect, can narrow, shallow, lighten and fade away striae gravidarum and scars with effective repair rate of 100%, harmlessly repair scar cells, prevent pigmentation, promote normal growth of skin cells, update scar tissue, recovery original memory of skin and restore beautiful skin.

Description

A kind of cosmetics of eliminating striae gravidarum and cicatrix
Technical field
The present invention relates to cosmetic field, be specifically related to eliminate the preparation of striae gravidarum and cicatrix.
Background technology
The modern times women that likes to be beautiful is more and more higher to the concern of self pretty figure, and that women's problem in various puerperal and cicatrix have had a strong impact on the women's that likes to be beautiful confidence and family is stable.And for repair puerperal striae gravidarum and the cicatrix problem more and more paid attention to, many industries have used diverse ways to repair striae gravidarum and cicatrix in puerperal, common method has following several:
1. quintessence oil champignon method, this method need interval procedure when repairing, the course of treatment is long, generally needs 6~12 months, and to cosmetologist's specification requirement height, the effect of the best only can make cyasma the superficial venule of the index finger being light in colourization 20%.
2. change the skin method, the method is to use the Chemopeel agent, uses acidity or corrosive substance more, therefore causes the propagation cicatrix easily and takes place, and the thin and responsive skin 50% of skin can cause the propagation cicatrix.Large tracts of land is used has harmful effect to health, and Skin Cell is impaired, influences metabolism.Chemical substance produces post precipitation and causes the skin pigment precipitation.
3. Photon Thherapy: by laser damaged skin is come off, this therapy can only the point-like treatment, and large tracts of land needs interval procedure, is difficult for grasping the depth.Easy skin ambustion, regular meeting stays cicatrix.
4. filing: large area treatment can bring misery and leave cicatrix to the patient, is not suitable for the striae gravidarum treatment.
5. premature labor method: though the premature labor method can be avoided the generation of striae gravidarum, having increased the ill probability of baby, also made a lot of babies innately retarded, is the method for nocuity maximum.
In sum, existing various puerperal striae gravidarum and cicatrix reparation ubiquity repairing effect undesirable, to drawbacks such as actual bodily harm are big, side effect is big.
Summary of the invention
The present invention aims to provide medicament of a kind of more safe and effective elimination striae gravidarum and cicatrix and preparation method thereof, to overcome the drawback that exists in the prior art.
Be to realize that the object of the invention, this cosmetics of eliminating striae gravidarum and cicatrix is characterized in that it is made by the raw material of following weight parts:
1,3 butanediol 1.8~2.3, nicotiamide 1.6~2.4, allantoin 0.08~0.13, antiseptic 0.1~0.6, cell growth factor 0.8~1.3, VB 20.6~1.5, Asiaticoside 0.85~1.35, cupu oil 2.0~3.0, collagen protein 2.5~3.5, deionized water 4~6.
Get material by above-mentioned prescription, be incubated 15~20 minutes after deionized water is heated to 85~95 ℃, add glycerol successively after the sterilization then, 1,3 butylene glycol, allantoin are cooled to 40~50 ℃ after stirring and dissolving is complete, and then add cell growth factor, cupu oil, collagen protein, VB successively 2, Asiaticoside and antiseptic, stirring and dissolving gets final product after fully.
Used 1,3 butanediol of the present invention is colourless, liquid of vicidity, has good hygroscopicity and bactericidal action, and people's mucosa and skin is had no stimulation.
Nicotiamide has another name called vitamin PP, be nadide and coenzyme II ingredient, play a part to pass hydrogen in the biological oxidation respiratory chain, nicotiamide can promote biological oxidation process and organize metabolism, to keep normal structure particularly the integrity of skin have important function.
The allantoin chemical name is 5-dioxo-4-imidazolidinyl urea, is a kind of nontoxic, tasteless, nonirritant, no hypersensitive white crystal, and allantoin once was called as counter-stimulus, and it has weak local paralysis effect, effectively the stimulation of abirritate thing.It also is a kind of antioxidant simultaneously, and is similar with the ability and the vitamin C of the same its set free radical of some other water soluble vitamins, so can strengthen the oxidation resistance of cell.Allantoin has weak local paralysis effect, the effective stimulation of abirritate thing, and it once was called as counter-stimulus, can promote cell to grow, accelerating wound, the proteic function of horny layer softening is the advantages of good skin Wound healing agent.Because allantoin is a kind of amphoteric compound, can form double salt in conjunction with multiple material, have lucifuge, sterilization and anticorrosion, pain relieving, antioxidation, can make skin keep moisture content, moist and soft.
Epithelical cell growth factor is a kind of important cells somatomedin of human endocrine, very strong physiologically active is arranged, can be initiatively with wound near specific receptor on the cell membrane combine, thereby the activator protein enzyme, accelerate proteinic synthesizing, its major function is the division that promotes Skin Cell.Studies show that: the EGF of denier can grow by the intense stimulus cell, suppresses aging gene and expresses, and strengthens the vigor of epidermis cell, delays wearing out of epidermis cell, the prevention skin aging, and each forms part best physiological status of maintenance to make skin.Synthetic and the secretion of its can also irritation cell outer macromole such as hyaluronic acid and collagen protein etc., skin care is decision skin vitality and healthy key factor.
Asiaticoside is a Herba Centellae extract, keratinocyte synthetic fibers cell there are obvious promotion increment and DNA anabolic effect, show through zoopery, intramuscular injection or subcutaneous implantation Asiaticoside can promote skin growth, application on human skin horn cell synthetic fibers cell all had tangible biological activity, fibroblastic ultrastructure can not only be influenced, and the synthetic of fibroblast proliferation and collagen protein can be suppressed.
Cupu oil can effectively nourish and protect the skin of dry hydropenia, can increase the elasticity and the degree of packing of skin; Glycerol has very strong hygroscopicity, can form thin film on skin, and secluding air and the effect that prevents water evaporates are arranged, and makes skin keep soft.
Collagen protein is that human body is concluded the main component in the tissue, accounts for 1/3rd of body internal protein total amount.Active collagen can directly infiltrate skin bottom, and good with the affinity of surrounding tissue, but helper cell manufactures collagen protein, impels Skin Cell normally to grow up.Collagen protein is strong to the permeability of skin, can see through horny layer and combine with the skin epithelial cell, participates in and improve the metabolism of Skin Cell, makes active reinforcement of collagen protein in the skin.It can keep the integrity of horny layer moisture and fibre structure, improves the metabolism of Skin Cell living environment and promotion skin histology, strengthens blood circulation, reaches the purpose of skin care.
The technological progress that the present invention obtains: the combination of each component of the present invention, can make skin keep moisture content, moist and soft, can promote the cell growth, accelerating wound promotes skin and mucosa wound healing and makes cicatrix shrink and suppress the lopsided hypertrophy of skin, quickens the reparation of injured epidermis cell, quicken metabolism, improve new cell proportion in skin, play enhancing reepithelialization ability, make skin full, keep skin elasticity with moist, strengthen the skin physiology function.Compared with similar products safely, effectively, have no side effect, can rebuild the destroyed fibre structure of abdominal part, allow striae gravidarum and cicatrix narrow down, shoal, thin out and subtract and take off, repair effective percentage and can reach 100%, the present invention can harmlessly repair the cicatrix cell, and the stimulating activity cell activates skin histology, replenishing collagen, rebuild elastic fiber, repair damaged cell, the fast updating connective tissue, deep layer is nourished skin, improve the crackle symptom of skin, strengthen the skin regeneration function, repair cicatrix gradually thereby repair activation damaged cell tissue.By the flow velocity of epidermis cell, the balance sebum secretion suppresses pigmentation, promotes the Skin Cell normal growth, and the more dead scar tissue of the old and new is recovered original memory of skin, thereby reappeared beautiful skin.
The specific embodiment
For further specifying the present invention, be further described below in conjunction with specific embodiment.
Embodiment 1: take by weighing 1,3 butanediol 20g respectively, nicotiamide 20g, allantoin 1g, methyl ester 2g, cell growth factor 10 g, VB 210g, Asiaticoside 10g, cupu oil 25g, collagen protein 30g, deionized water 50g.
After getting material by above-mentioned prescription, be incubated 15~20 minutes after deionized water is heated to 85~95 ℃, the sterilization back adds glycerol then, 1,3 butylene glycol, allantoin are cooled to 45~50 ℃ after stirring and dissolving is complete, and then add cell growth factor, cupu oil, collagen protein, VB successively 2, Asiaticoside and methyl ester antiseptic, stirring and dissolving gets final product after fully.
Wherein used 1,3 butanediol of the present invention is produced by the safe outstanding Chemical Industry Science Co., Ltd in Guangzhou; Nicotiamide is by the blue rich bio tech ltd production in Zhejiang; Allantoin is produced by Shandong Qingzhou Ailitong Chemicals Technical Co., Ltd.; Epithelical cell growth factor (EGF) is produced by Zhuhai Grace cosmetics company limited; Asiaticoside is produced by Guangxi Chang Zhou natural product development corporation, Ltd.; Antiseptic methyl ester, propyl ester are produced by Beijing Sang Pu biochemical technology company limited, and germall tlus is by the U.S.'s international special product company limited production; Collagen protein is produced by Shanghai Shou Yuan Bioisystech Co., Ltd, and its molecular weight is 3000 dalton, or adopts the collagen protein product of molecular weight between 1500~3000 dalton, and its activity is the strongest, and assimilation effect is best.
Other embodiment difference from Example 1 sees the following form:
Unit: g
Figure GSA00000022005300051
For checking effect of the present invention, from the women of the different time limits in puerperal, select 100 as the trier.Following table is that the striae gravidarum behind use the present invention is repaired statistical conditions, and wherein the clinical repair standard is: invalid standard is: skin and reparation are before without any change; Effectively standard is: skin surface tightens up, not lax and obvious wrinkle; Fully repairing standard is: skin consolidation, the colour of skin are evenly, not aberration with other position colour of skin.
Striae gravidarum clinical repair statistical table
Figure GSA00000022005300052
Wherein using method is: behind the clean skin, get an amount of the present invention and be applied to abdominal part, buttocks and thigh place, pat and be massaged into absorption.Every day 3 times, massaged 5~10 minutes at every turn, be 1~3 month service time continuously.
Be checking effect of the present invention, never have among the crowd of operative scar and select 200 as the trier with the time limit.Following table is that the cicatrix behind use the present invention is repaired statistical conditions.Wherein the clinical repair standard is: invalid: cicatrix is not seen any change after repairing; Effectively: after repairing the operation local cicatrix deliquescing, flatten; Repair fully: pachyderma, elasticity increase through repairing after, skin wrinkle is obvious, the twinge of very itching disappearance, cicatrix and other skin no significant difference.Wherein restorative procedure is: behind the clean skin, get an amount of the present invention and be applied to the cicatrix place, pat and be massaged into absorption.Every day 3 times, massaged 5~10 minutes at every turn, be 1~3 month service time continuously.
Cicatrix clinical repair statistical table
Figure GSA00000022005300061
Can find out from above clinical repair statistics:
1. indication of the present invention is extensive, to various types of striae gravidarum, operative scar, repairs the elastic webs of impaired fracture from skin corium, and 15 days take effect, and has clear improvement in 1 month, repaired fully in 3~6 months, and effective percentage 100%, repair rate is more than 75% fully.
2. colorless and odorless has no side effect.The present invention is none routine anaphylaxis in 300 people's test crowd.Be that the present invention is non-stimulated to skin, mucosa, safe in utilization.
3. there is not the Chemopeel agent, no acidic material, non-corrosiveness material.Can harmlessly repair elastic fiber and cicatrix cell, activate skin histology, strengthen the skin regeneration function, safeguard the skin environmental health.
The present invention is as follows in some typical cases of aesthetic nursing clinical practice:
Case 1: Zhang Xiaoning, the woman, 35 years old, Qian'an people from town, Qianan City, Hebei province, daughter 5 years old had striae gravidarum 5 years, and the skin fiber fracture is serious.Bring into use the preparation of the embodiment of the invention 1 preparation in January, 2009, repair fully after five months.
Case 2: Yang Xiaomei, the woman, 33 years old, Qianan City, Hebei province poplar was coughed up people from village, does caesarean operation before the Yu Banian, stays cicatrix and is about 12cm.Bring into use the preparation of the embodiment of the invention 2 preparation in March, 2009, use that cicatrix occurs disconnecting phenomenon after one month, adhere to using after three months cicatrix to repair the line that looks like a white, after use two months again after, cicatrix is repaired fully.
Case 3: Yang Hua, the woman, 36 years old, Qian'an town, Qianan City, Hebei province resident performed an operation in 2008, stayed about 5cm cicatrix in shank, and the preparation that uses the embodiment of the invention 3 preparations is after three months, and cicatrix is repaired fully.
Case 4: Ma Huandi, woman, 28 years old, resident in the Qianan City, Hebei province, son is given birth in natural labor in 2007, and striae gravidarum is serious, cutis laxa, the preparation of the use embodiment of the invention 1 preparation is skin recovery elasticity after one month, striae gravidarum obviously narrows down, and the preparation that continues to use the embodiment of the invention 2 preparations is after two months, and striae gravidarum disappears substantially, after used again one month, skin is repaired fully.
Case 5: Zhang Hong, the woman, 26 years old, Qianan City, the Hebei province pheasant resident that sticks together, cesarean was given birth to daughter in 2006, because fetus is bigger, striae gravidarum is serious, and scar is arranged.Use the preparation of the embodiment of the invention 5 preparations to repair cicatrix and striae gravidarum simultaneously, cicatrix obtains repairing after using three months, and striae gravidarum is repaired after using six months fully.
Case 6: Li Xiaoyu, woman, 18 years old, Qianan City, Hebei province button people from village, arm injury in 2008 stays and is about the 3cm cicatrix, influences attractive in appearancely, and the preparation of this use inventive embodiments 6 preparation is after one month, and the cicatrix color is thin out, and shorten, use three months continuously after, cicatrix is repaired fully.
Case 7: Zhang Ran, the woman, 40 years old, Qianan City, Hebei province owner of a private enterprise had daughter 18 years old in the family, son 10 years old.Because secondary production, skin is very lax, the build obesity.Abdominal part, buttocks all have serious striae gravidarum, and striae gravidarum has become silvery white.The preparation that uses inventive embodiments 7 preparations after six months skin begin to recover elasticity, skin is glossy, the striae gravidarum color is near the normal colour of skin.
Case 8: Lang Xiaoying, the woman, 28 years old, Qian'an people from town, Qianan City, Hebei province, natural labor daughter in 2009, two months puerperal, striae gravidarum takes on a red color, and behind the preparation two weeks of the use embodiment of the invention 8 preparations, redness is taken off, skin color is near the normal colour of skin, after adhere to using after two months striae gravidarum to repair fully again.
Case 9: Yang Meili, the woman, 35 years old, Qianan City, Hebei province poplar was coughed up village resident, and on November 20th, 2008 performed an operation, and stayed cicatrix in abdominal part, repaired fully behind two first quarter moons of preparation that use the embodiment of the invention 9 to prepare in May, 2009.
Case 10: Xu Yan, the woman, 24 years old, resident in the Qianan City, Hebei province, after the natural labor on March 10 in 2009, the huckle striae gravidarum is serious.Bring into use the preparation of the embodiment of the invention 10 preparations in June, 2009, striae gravidarum is repaired fully after three months.

Claims (3)

1. the cosmetics that can eliminate striae gravidarum and cicatrix is characterized in that it is made by the raw material of following weight parts:
1,3 butanediol 1.8~2.3, nicotiamide 1.6~2.4, allantoin 0.08~0.13, antiseptic 0.05~0.6, cell growth factor 0.8~1.3, VB 20.6~1.5, Asiaticoside 0.85~1.35, cupu oil 2.0~3.0, glycerol 2.5~3.5, collagen protein 2.5~3.5, deionized water 4~6;
Get material by above-mentioned prescription, be incubated 15~20 minutes after deionized water is heated to 85~95 ℃, add glycerol successively after the sterilization then, 1,3 butylene glycol, allantoin are cooled to 40~50 ℃ after stirring and dissolving is complete, and then add cell growth factor, cupu oil, collagen protein, VB successively 2, Asiaticoside and antiseptic, stirring and dissolving gets final product after fully.
2. the cosmetics of eliminating striae gravidarum and cicatrix according to claim 1 is characterized in that described each raw material weight umber ratio is:
1,3 butanediol 2.00, nicotiamide 2.00, allantoin 0.10, antiseptic 0.20, growth factor-21 .00, VB21.00, Asiaticoside 1.00, cupu oil 2.50, collagen protein 3.00, deionized water 5.00.
3. the cosmetics of eliminating striae gravidarum and cicatrix according to claim 1 and 2 is characterized in that described antiseptic adopts methyl ester, propyl ester or germall tlus.
CN2010101065522A 2010-02-05 2010-02-05 Cosmetic capable of eliminating striae gravidarum and scars Expired - Fee Related CN101791283B (en)

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CN102973466A (en) * 2012-12-13 2013-03-20 浙江久晟茶业发展有限公司 Cosmetic used for removing stretch marks and prepared by camellia oil and preparation method thereof
CN103961269A (en) * 2013-02-01 2014-08-06 大连美诺伊生物科技有限公司 striae gravidarum repair paste and repair method thereof
CN104546606A (en) * 2014-12-26 2015-04-29 青蛙王子(中国)日化有限公司 Oil-in-water stretch marks remover and preparation method thereof
CN104814901A (en) * 2015-05-18 2015-08-05 南阳市汇博生物技术有限公司 Striae gravidarum preventing gel and preparation method thereof
CN105708722A (en) * 2016-03-15 2016-06-29 深圳市真兴病毒技术有限公司 Factor composition and composite freeze-dried powder for promoting skin cell growth and skin care product
CN105816377A (en) * 2016-04-15 2016-08-03 冯昱钦 Wrinkle-free repair cream and preparation method thereof
CN106362141A (en) * 2016-11-22 2017-02-01 郑州兰茜生物工程有限公司 Safe and multi-effect freckle removing agent and preparation method thereof
CN107028830A (en) * 2017-04-25 2017-08-11 徐子雁 It is a kind of to prevent the medicine and its preparation technology of scar hyperplasia
CN108030754A (en) * 2017-12-29 2018-05-15 吕玲 A kind of face cream for eliminating striae of pregnancy and desalinating scar and preparation method thereof
CN108904393A (en) * 2018-09-20 2018-11-30 浙江美之源化妆品有限公司 A kind of preparation method for desalinating skin orange peel line and moisturizing whitening type body lotion

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CN102973466A (en) * 2012-12-13 2013-03-20 浙江久晟茶业发展有限公司 Cosmetic used for removing stretch marks and prepared by camellia oil and preparation method thereof
CN102973466B (en) * 2012-12-13 2015-01-28 浙江久晟茶业发展有限公司 Cosmetic used for removing stretch marks and prepared by camellia oil and preparation method thereof
CN103961269A (en) * 2013-02-01 2014-08-06 大连美诺伊生物科技有限公司 striae gravidarum repair paste and repair method thereof
CN104546606A (en) * 2014-12-26 2015-04-29 青蛙王子(中国)日化有限公司 Oil-in-water stretch marks remover and preparation method thereof
CN104546606B (en) * 2014-12-26 2017-12-29 青蛙王子(中国)日化有限公司 A kind of oil-in-water is dispelled striae of pregnancy frost and preparation method thereof
CN104814901B (en) * 2015-05-18 2017-10-24 河南汇博医疗股份有限公司 One kind prevention striae of pregnancy gel and preparation method thereof
CN104814901A (en) * 2015-05-18 2015-08-05 南阳市汇博生物技术有限公司 Striae gravidarum preventing gel and preparation method thereof
CN105708722A (en) * 2016-03-15 2016-06-29 深圳市真兴病毒技术有限公司 Factor composition and composite freeze-dried powder for promoting skin cell growth and skin care product
CN105816377A (en) * 2016-04-15 2016-08-03 冯昱钦 Wrinkle-free repair cream and preparation method thereof
CN106362141A (en) * 2016-11-22 2017-02-01 郑州兰茜生物工程有限公司 Safe and multi-effect freckle removing agent and preparation method thereof
CN107028830A (en) * 2017-04-25 2017-08-11 徐子雁 It is a kind of to prevent the medicine and its preparation technology of scar hyperplasia
CN107028830B (en) * 2017-04-25 2021-03-09 徐子雁 Medicine for preventing scar hyperplasia and preparation process thereof
CN108030754A (en) * 2017-12-29 2018-05-15 吕玲 A kind of face cream for eliminating striae of pregnancy and desalinating scar and preparation method thereof
CN108904393A (en) * 2018-09-20 2018-11-30 浙江美之源化妆品有限公司 A kind of preparation method for desalinating skin orange peel line and moisturizing whitening type body lotion

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