CN105125476B - A kind of anti-wrinkle essence and preparation method thereof - Google Patents
A kind of anti-wrinkle essence and preparation method thereof Download PDFInfo
- Publication number
- CN105125476B CN105125476B CN201510673049.8A CN201510673049A CN105125476B CN 105125476 B CN105125476 B CN 105125476B CN 201510673049 A CN201510673049 A CN 201510673049A CN 105125476 B CN105125476 B CN 105125476B
- Authority
- CN
- China
- Prior art keywords
- elite
- essence
- wrinkle
- alcohol
- skin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/99—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/981—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of mammals or bird
- A61K8/986—Milk; Derivatives thereof, e.g. butter
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
- A61K2800/782—Enzyme inhibitors; Enzyme antagonists
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Dermatology (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Cosmetics (AREA)
Abstract
The invention belongs to cosmetic technical fields, and in particular to a kind of anti-wrinkle essence and preparation method thereof.The anti-wrinkle essence includes cyclomethicone, butanediol, dimethyl silicone polymer, polyglutamic acid sodium, glycerine, propylene glycol, polyglycereol 10, dipropylene glycol, erythrite, hydroxy-ethyl acrylate/sodium acryloyldimethyl taurate copolymers, biological carbohydrate gum 1, xylitol, 22 alcohol phosphates of C20/22 alcohol of C20, Bacillus acidi lactici/pomegranate fruit tunning extract, arctic Ascophyllum nodosum elite, starfish elite, hexapeptide 3, flores aurantii elite, rough gentian root extract, ursin, milk protein, tranexamic acid etc., its good penetrability, easily absorb, effective replenishing water and preserving moisture, repair wrinkle of skin, inhibit wrinkle regeneration, delay skin aging.
Description
Technical field
The present invention relates to cosmetic technical fields, and in particular to a kind of anti-wrinkle essence and preparation method thereof.
Background technology
Puberty is people's most pretty beautiful period in life, at this time skin slip, gloss, plentiful, high resilience, Bai Li
It is thoroughly red.To after 25 years old, metabolism starts to slow down, and moisture and subcutaneous fat are reduced, and elastomer is gradually thicker, and skin becomes
Wrinkle, gloss disappear.After 40 years old, hormone in vivo dysequilibrium, keratin reduce, elastic fibers break, cutis laxa, it is coarse,
Wrinkle increases, and progresses into aging period.Skin aging is the outstanding behaviours of entire body aging, and wherein facial skin aging is particularly
Substantially, fibroblastic quantity gradually decreases in human body, and the collagen and elastic fibers albumen of secretion are also because by oxygen
Change gradually decrease, be broken, just disappear to the supporting role of epidermis, cause it is inhomogenous collapse, skin corium starts thinning, skin bullet
Property be deteriorated, wrinkle also begins to gradually generate.
Skin aging by objective factors such as age, heredity in addition to being influenced, also by many factors such as daylight, environment, health
It influences.Undue solarization is exposed to the sun, and is not only speeded up skin aging, is also also easy to produce pigmented spots；Seriously polluted environment is lived in for a long time
In or excessively contact the chemical substance being harmful to skin, can all make skin damage, accelerated ageing；Malnutrition, lassitude, disease
Disease is burdened with, and skin is more easy to premature aging.Particularly modern life pressure is big, overtime work stays up late, for a long time to computer, smoke, sleep
Sleep deficiency, stay in air-conditioned room for a long time, drink, excess eye-using etc. becomes life normality.According to the U.S. beautiful scientific center of Dior Christian Dior
Research, daily, each layer of skin can be accumulated largely as the cellular elements toxin caused by inherent or external factor, and skin can be caused thin
Born of the same parents suffocate, and affect the toxin Scavenging activity of skin itself, and so as to just generate, the colour of skin is obscure, lack gloss, tired state is showed fully
Etc. worries；The burden of skin has been aggravated, has accelerated skin aging.
Although skin aging is irreversible physiological phenomenon, its process can delay or slow down.For face wrinkles,
Common anti-wrinkle method is operation smoothing wrinkle, injection anti-wrinkle and anti-wrinkle cosmetic.The treatment cost height of smoothing wrinkle of performing the operation and injection anti-wrinkle,
Risk is big, is not that each consumer can bear, and anti-wrinkle cosmetic is a selection well.Anti-wrinkle cosmetic is again
It is a variety of to be divided into anti-wrinkle face mask, mildy wash, crease-resistant toner, face cream, Essence etc., anti-wrinkle face mask, mildy wash face stop
Time is short, and effect unobvious are and also inconvenient using process, it is necessary to long-time service；Active ingredient in crease-resistant toner, face cream
Content is relatively low, anti-wrinkle effect also unobvious, and nutriment and active ingredient that Essence contains are compared with toner, face cream
High more, effect is powerful, and anti-wrinkle effect is notable, but current Essence commonly there are poor permeability, be not easy to absorb
Problem, and anti-wrinkle effect need to be improved.
It therefore, it is necessary to research and develop its a kind of good penetrability, easily absorbs, effective replenishing water and preserving moisture, repairs wrinkle of skin, inhibit wrinkle
Line regenerates, delay skin aging anti-wrinkle essence.
The content of the invention
For overcome the deficiencies in the prior art, it is an object of the invention to provide a kind of anti-wrinkle essence, good penetrability,
It easily absorbs, effective replenishing water and preserving moisture, repairs wrinkle of skin, inhibit wrinkle regeneration, delay skin aging.
To achieve these goals, technical scheme is as follows：
A kind of anti-wrinkle essence includes the raw material of following weight percent meter：Cyclomethicone 4 ~ 10%, fourth two
Alcohol 4 ~ 10%, dimethyl silicone polymer 2 ~ 8%, polyglutamic acid sodium 1 ~ 5%, glycerine 0.5 ~ 4%, propylene glycol 0.5 ~ 4%, Natrulon H-10
0.5 ~ 4%, dipropylene glycol 0.5 ~ 4%, erythrite 0.5 ~ 4%, hydroxy-ethyl acrylate/sodium acryloyldimethyl taurate copolymers 0.5
~ 4%, biological carbohydrate gum -1 0.5 ~ 3%, xylitol 0.5 ~ 3%, C20-22 alcohol phosphate/C20-22 alcohol 0.5 ~ 3%, Bacillus acidi lactici/stone
Pomegranate fruit tunning extract 0.3 ~ 2%, arctic Ascophyllum nodosum elite 0.3 ~ 2%, starfish elite 0.3 ~ 2%, hexapeptide -3 0.3 ~ 2%, orange
Anthosin China 0.3 ~ 2%, rough gentian root extract 0.3 ~ 2%, ursin 0.1 ~ 1%, milk protein 0.1 ~ 1%, tranexamic acid 0.05 ~ 1%, hydroxyl
Benzene methyl 0.01 ~ 0.1%, Phenoxyethanol 0.01 ~ 0.1%, essence 0.0002 ~ 0.05% and water 40 ~ 70%.
Further, the anti-wrinkle essence includes the raw material of following weight percent meter：Cyclomethicone 4
~ 8%, butanediol 4 ~ 8%, dimethyl silicone polymer 2 ~ 6%, polyglutamic acid sodium 1 ~ 4%, glycerine 0.5 ~ 3%, propylene glycol 0.5 ~ 3%, poly- sweet
Oil -10 0.5 ~ 3%, dipropylene glycol 0.5 ~ 2%, erythrite 0.5 ~ 2%, hydroxy-ethyl acrylate/sodium acryloyldimethyl taurate are common
Polymers 0.5 ~ 2%, biological carbohydrate gum -1 0.5 ~ 1.5%, xylitol 0.5 ~ 1.5%, C20-22 alcohol phosphate/C20-22 alcohol 0.5 ~
1.5%th, Bacillus acidi lactici/pomegranate fruit tunning extract 0.3 ~ 1%, arctic Ascophyllum nodosum elite 0.3 ~ 1%, starfish elite 0.3 ~ 1%,
Hexapeptide -3 0.3 ~ 1%, flores aurantii elite 0.3 ~ 1%, rough gentian root extract 0.3 ~ 1%, ursin 0.1 ~ 0.6%, milk protein 0.1 ~
0.6%th, tranexamic acid 0.05 ~ 0.3%, methyl hydroxybenzoate 0.01 ~ 0.05%, Phenoxyethanol 0.01 ~ 0.05%, 0.0002 ~ 0.01% He of essence
Water 60 ~ 70%.
As the preferred embodiment of the present invention, the anti-wrinkle essence by following weight percent meter raw material group
Into：Cyclomethicone 6%, butanediol 6%, dimethyl silicone polymer 3%, polyglutamic acid sodium 2%, glycerine 2%, propylene glycol
1.5%th, Natrulon H-10 1.5%, dipropylene glycol 1%, erythrite 1%, hydroxy-ethyl acrylate/sodium acryloyldimethyl taurate copolymerization
Object 1%, biological carbohydrate gum -1 0.8%, xylitol 0.8%, C20-22 alcohol phosphate/C20-22 alcohol 0.8%, Bacillus acidi lactici/pomegranate fruit
Tunning extract 0.5%, arctic Ascophyllum nodosum elite 0.6%, starfish elite 0.5%, hexapeptide -3 0.6%, flores aurantii elite 0.5%,
Rough gentian root extract 0.5%, ursin 0.2%, milk protein 0.2%, tranexamic acid 0.1%, methyl hydroxybenzoate 0.01%, Phenoxyethanol
0.01%th, essence 0.0015% and water 68.8785%.
In the technical solution of the present invention, the Bacillus acidi lactici/pomegranate fruit tunning extract contain substantial amounts of ellagic acid,
Polyphenol and anthocyanidin, inoxidizability is strong, can effectively neutralize free radical, boost metabolism, and reduces visible microgroove.
The arctic Ascophyllum nodosum elite is micro rich in phycocolloid body, brown algae polyphenols, sodium alginate, algae carrotene and ocean
Element can increase skin thickness, the mechanical performance for improving skin, improve barrier function, promote collagen and elastin laminin
And into, inhibit degrading enzyme, so as to improve the texture, color and luster and brightness of skin.
The starfish elite can promote the metabolism of skin, increase epidermal barrier regeneration, while more increase glycosaminoglycan
（GAGS）With the III, synthesis of type Ⅳ collagen albumen, skin is helped to effectively antagonize wrinkle, makes skin water tender flexible, and does not have
Any side effect and irritation.
The hexapeptide -3 have it is similar can inhibit neurotransmitter, conduction function between block nerves muscle avoids muscle
Excess shrinkage prevents microgroove from being formed, additionally it is possible to which the strength of contraction of muscle can be delayed by subtracting, and allow loosening all muscles, reduce the generation of dynamic line
With eliminating microgroove, collagen elastic force is effectively reorganized, the activity of elastin can be increased, loosen face's lines, wrinkle is comforted
It is flat to improve relaxation.
The flores aurantii elite contains a variety of whitening active ingredients, can export established melanin in skin layer by layer, and with
It the metabolism of aging cutin and excludes, skin is gradually pale while can also exclude the turbidity of aggregation in skin and be generated due to pollution
Harmful substance, enhance cell viability, help cytothesis, increase skin elasticity.
The rough gentian root extract can help to eliminate that skin surface is obscure, while effectively inhibit the formation of melanin, light
Change color spot, bright color, net white muscle skin.
The milk protein, which contains hydrophily moisturizing ingredient, can protect skin total moisture to prevent from being lost in, a variety of aminoacid ingredients
It can promote the quick reparation of damage skin, the content of albumen in skin can be enriched, while the intensity of connective tissue can be enhanced, can promote
Albumen is generated into skin, prevents and reduces wrinkle, make skin plentiful and flexible.
Anti-wrinkle essence of the present invention contains Bacillus acidi lactici/pomegranate fruit tunning extract, arctic Ascophyllum nodosum elite, starfish
The various plants compositions such as elite, flores aurantii elite, rough gentian root extract, in conjunction with cyclomethicone of the present invention, butanediol,
The basic materials such as dimethyl silicone polymer, polyglutamic acid sodium, glycerine, propylene glycol, Natrulon H-10, each component collaboration so that this hair
Bright anti-wrinkle essence good penetrability easily absorbs, deep water supplement moisturizing, nourishes maintenance skin, promotes cytothesis, repairs skin wrinkle
Line inhibits wrinkle regeneration, and delay skin aging, improvement cutis laxa is sagging, and skin lightening is compacted, and it is slight to promote skin year.
The present invention also provides the preparation methods of above-mentioned anti-wrinkle essence, specifically include following steps：
S1, by cyclomethicone, dimethyl silicone polymer and C20-22 alcohol phosphate/C20-22 alcohol, add in oil
In phase pot, 80 ~ 85 DEG C are heated to, stirs to being completely dissolved, obtains material A；
S2, Jiang Shui, butanediol, polyglutamic acid sodium, glycerine, propylene glycol, Natrulon H-10, dipropylene glycol, erythrite, xylose
Alcohol, ursin and methyl hydroxybenzoate are added in water phase pot, are heated to 80 ~ 85 DEG C, are stirred to being completely dissolved, are obtained material B；
S3, material A and material B are pumped into emulsification pot, open homogeneous, 5 ~ 10min of homogeneous, 10 ~ 20min of insulated and stirred；
S4,40 ~ 45 DEG C are cooled to, add in hydroxy-ethyl acrylate/sodium acryloyldimethyl taurate copolymers, biology sugar
Glue -1, Bacillus acidi lactici/pomegranate fruit tunning extract, arctic Ascophyllum nodosum elite, starfish elite, hexapeptide -3, flores aurantii elite, dragon
Courage root extract, milk protein, tranexamic acid, Phenoxyethanol and essence, stir evenly, you can anti-wrinkle essence is made in discharging.
Further, the mixing speed of the stirring is 40 ~ 50 r/min.
Therefore, compared with prior art, advantage of the invention is that：
（1）Anti-wrinkle essence of the present invention contain Bacillus acidi lactici/pomegranate fruit tunning extract, arctic Ascophyllum nodosum elite,
A variety of natural extracts such as starfish elite, flores aurantii elite and rough gentian root extract, can efficiently moisturizing, moisturizing, give skin supply battalion
It supports, promotes skin metabolism, effectively calm down microgroove, reduce wrinkle, slowing down skin aging, improvement cutis laxa is sagging, skin lightening
It compacts, and long-acting moisturizing, skin water is made to moisten smooth, high resilience, it is slight to promote skin year.
（2）Anti-wrinkle essence safety and stability of the present invention, good penetrability easily absorb, clearly not sticky using rear face；And this
The preparation method of invention anti-wrinkle essence is simple, and condition is controllable, process stabilizing, can be applicable.
Specific embodiment
The present invention is further described below by way of specific embodiment, but the present invention is not limited only to following embodiment.
In the scope of the present invention or do not departing from present disclosure, in spirit and scope, to anti-wrinkle essence of the present invention into
Row is suitably modified, replaces the identical component of effect, it will become apparent to those skilled in the art that they are considered as
It is included within the scope of the present invention.
The information such as the producer of part material and article No. are as follows in anti-wrinkle essence described in the embodiment of the present invention：
Embodiment 1, anti-wrinkle essence of the present invention and its preparation
Formula：It is made of the raw material of following weight percent meter：Cyclomethicone 6%, butanediol 6%, poly- diformazan
Radical siloxane 3%, polyglutamic acid sodium 2%, glycerine 2%, propylene glycol 1.5%, Natrulon H-10 1.5%, dipropylene glycol 1%, erythrite 1%,
Hydroxy-ethyl acrylate/sodium acryloyldimethyl taurate copolymers 1%, biological carbohydrate gum -1 0.8%, xylitol 0.8%, C20-22 alcohol
Phosphate/C20-22 alcohol 0.8%, Bacillus acidi lactici/pomegranate fruit tunning extract 0.5%, arctic Ascophyllum nodosum elite 0.6%, sea
Star elite 0.5%, hexapeptide -3 0.6%, flores aurantii elite 0.5%, rough gentian root extract 0.5%, ursin 0.2%, milk protein 0.2%,
Tranexamic acid 0.1%, methyl hydroxybenzoate 0.01%, Phenoxyethanol 0.01%, essence 0.0015% and water 68.8785%.
Preparation method：
S1, by cyclomethicone, dimethyl silicone polymer and C20-22 alcohol phosphate/C20-22 alcohol, add in oil
In phase pot, 80 DEG C are heated to, stirs to being completely dissolved, obtains material A；
S2, Jiang Shui, butanediol, polyglutamic acid sodium, glycerine, propylene glycol, Natrulon H-10, dipropylene glycol, erythrite, xylose
Alcohol, ursin and methyl hydroxybenzoate are added in water phase pot, are heated to 80 DEG C, are stirred to being completely dissolved, are obtained material B；
S3, material A and material B are pumped into emulsification pot, open homogeneous, homogeneous 10min, insulated and stirred 15min；
S4,40 DEG C are cooled to, add in hydroxy-ethyl acrylate/sodium acryloyldimethyl taurate copolymers, biological carbohydrate gum -1,
Bacillus acidi lactici/pomegranate fruit tunning extract, arctic Ascophyllum nodosum elite, starfish elite, hexapeptide -3, flores aurantii elite, gentian
Extract, milk protein, tranexamic acid, Phenoxyethanol and essence, stir evenly, you can anti-wrinkle essence is made in discharging.
The mixing speed of the stirring is 45r/min.
Embodiment 2, anti-wrinkle essence of the present invention and its preparation
Formula：It is made of the raw material of following weight percent meter：Cyclomethicone 4%, butanediol 4%, poly- diformazan
Radical siloxane 6%, polyglutamic acid sodium 1%, glycerine 3%, propylene glycol 0.5%, Natrulon H-10 3%, dipropylene glycol 0.5%, erythrite 2%,
Hydroxy-ethyl acrylate/sodium acryloyldimethyl taurate copolymers 0.5%, biological carbohydrate gum -1 1.5%, xylitol 0.5%, C20-22
Alcohol phosphate/C20-22 alcohol 1.5%, Bacillus acidi lactici/pomegranate fruit tunning extract 0.3%, arctic Ascophyllum nodosum elite 1%, sea
Star elite 0.3%, hexapeptide -3 1%, flores aurantii elite 0.3%, rough gentian root extract 1%, ursin 0.1%, milk protein 0.6%, blood coagulation
Acid 0.05%, methyl hydroxybenzoate 0.01%, Phenoxyethanol 0.05%, essence 0.01% and water 67.28%.
Preparation method：
S1, by cyclomethicone, dimethyl silicone polymer and C20-22 alcohol phosphate/C20-22 alcohol, add in oil
In phase pot, 85 DEG C are heated to, stirs to being completely dissolved, obtains material A；
S2, Jiang Shui, butanediol, polyglutamic acid sodium, glycerine, propylene glycol, Natrulon H-10, dipropylene glycol, erythrite, xylose
Alcohol, ursin and methyl hydroxybenzoate are added in water phase pot, are heated to 85 DEG C, are stirred to being completely dissolved, are obtained material B；
S3, material A and material B are pumped into emulsification pot, open homogeneous, homogeneous 5min, insulated and stirred 20min；
S4,45 DEG C are cooled to, add in hydroxy-ethyl acrylate/sodium acryloyldimethyl taurate copolymers, biological carbohydrate gum -1,
Bacillus acidi lactici/pomegranate fruit tunning extract, arctic Ascophyllum nodosum elite, starfish elite, hexapeptide -3, flores aurantii elite, gentian
Extract, milk protein, tranexamic acid, Phenoxyethanol and essence, stir evenly, you can anti-wrinkle essence is made in discharging.
The mixing speed of the stirring is 40 r/min.
Embodiment 3, anti-wrinkle essence of the present invention and its preparation
Formula：It is made of the raw material of following weight percent meter：Cyclomethicone 8%, butanediol 8%, poly- diformazan
Radical siloxane 2%, polyglutamic acid sodium 4%, glycerine 0.5%, propylene glycol 3%, Natrulon H-10 0.5%, dipropylene glycol 2%, erythrite
0.5%th, hydroxy-ethyl acrylate/sodium acryloyldimethyl taurate copolymers 2%, biological carbohydrate gum -1 0.5%, xylitol 1.5%,
C20-22 alcohol phosphate/C20-22 alcohol 0.5%, Bacillus acidi lactici/pomegranate fruit tunning extract 1%, arctic Ascophyllum nodosum elite
0.3%th, starfish elite 1%, hexapeptide -3 0.3%, flores aurantii elite 1%, rough gentian root extract 0.3%, ursin 0.6%, milk protein
0.1%th, tranexamic acid 0.3%, methyl hydroxybenzoate 0.05%, Phenoxyethanol 0.01%, essence 0.01% and water 62.03%.
Preparation method：
S1, by cyclomethicone, dimethyl silicone polymer and C20-22 alcohol phosphate/C20-22 alcohol, add in oil
In phase pot, 80 DEG C are heated to, stirs to being completely dissolved, obtains material A；
S2, Jiang Shui, butanediol, polyglutamic acid sodium, glycerine, propylene glycol, Natrulon H-10, dipropylene glycol, erythrite, xylose
Alcohol, ursin and methyl hydroxybenzoate are added in water phase pot, are heated to 80 DEG C, are stirred to being completely dissolved, are obtained material B；
S3, material A and material B are pumped into emulsification pot, open homogeneous, homogeneous 10min, insulated and stirred 10min；
S4,40 DEG C are cooled to, add in hydroxy-ethyl acrylate/sodium acryloyldimethyl taurate copolymers, biological carbohydrate gum -1,
Bacillus acidi lactici/pomegranate fruit tunning extract, arctic Ascophyllum nodosum elite, starfish elite, hexapeptide -3, flores aurantii elite, gentian
Extract, milk protein, tranexamic acid, Phenoxyethanol and essence, stir evenly, you can anti-wrinkle essence is made in discharging.
The mixing speed of the stirring is 50 r/min.
Embodiment 4, anti-wrinkle essence of the present invention and its preparation
Formula：It is made of the raw material of following weight percent meter：Cyclomethicone 4%, butanediol 4%, poly- diformazan
Radical siloxane 8%, polyglutamic acid sodium 1%, glycerine 4%, propylene glycol 0.5%, Natrulon H-10 4%, dipropylene glycol 4%, erythrite 0.5%,
Hydroxy-ethyl acrylate/sodium acryloyldimethyl taurate copolymers 4%, biological carbohydrate gum -1 0.5%, xylitol 3%, C20-22 alcohol phosphorus
Acid esters/C20-22 alcohol 0.5%, Bacillus acidi lactici/pomegranate fruit tunning extract 0.3%, arctic Ascophyllum nodosum elite 0.3%, starfish
Elite 0.3%, hexapeptide -3 0.3%, flores aurantii elite 0.3%, rough gentian root extract 0.3%, ursin 1%, milk protein 1%, tranexamic acid
1%th, methyl hydroxybenzoate 0.01%, Phenoxyethanol 0.1%, essence 0.05% and water 57.04%.
Preparation method is the same as embodiment 1.
Embodiment 5, anti-wrinkle essence of the present invention and its preparation
Formula：It is made of the raw material of following weight percent meter：Cyclomethicone 10%, butanediol 10%, poly- two
Methylsiloxane 2%, polyglutamic acid sodium 5%, glycerine 0.5%, propylene glycol 4%, Natrulon H-10 0.5%, dipropylene glycol 0.5%, red moss
Alcohol 4%, hydroxy-ethyl acrylate/sodium acryloyldimethyl taurate copolymers 0.5%, biological carbohydrate gum -1 3%, xylitol 3%, C20-
22 alcohol phosphates/C20-22 alcohol 3%, Bacillus acidi lactici/pomegranate fruit tunning extract 2%, arctic Ascophyllum nodosum elite 2%, starfish
Elite 2%, hexapeptide -3 2%, flores aurantii elite 2%, rough gentian root extract 2%, ursin 0.1%, milk protein 0.1%, tranexamic acid
0.05%th, methyl hydroxybenzoate 0.1%, Phenoxyethanol 0.01%, essence 0.01% and water 41.63%.
Preparation method is the same as embodiment 1.
Through examining, the pertinent regulations that anti-wrinkle essence made from the embodiment of the present invention 1 ~ 5 meets QB/T 2660-2004 will
It asks, sense index（Color and luster, fragrance, structure）Meet industry regulation, physical and chemical index（PH, heat-resisting, cold-resistant, active matter）Meet industry
Regulation.
Comparative example 1,
Formula：It is made of the raw material of following weight percent meter：Cyclomethicone 6%, butanediol 6%, poly- diformazan
Radical siloxane 3%, polyglutamic acid sodium 2%, glycerine 2%, propylene glycol 1.5%, Natrulon H-10 1.5%, dipropylene glycol 1%, erythrite 1%,
Hydroxy-ethyl acrylate/sodium acryloyldimethyl taurate copolymers 1%, biological carbohydrate gum -1 0.8%, xylitol 0.8%, C20-22 alcohol
Phosphate/C20-22 alcohol 0.8%, hexapeptide -3 1.2%, flores aurantii elite 1%, rough gentian root extract 1%, ursin 0.2%, milk egg
White 0.2%, tranexamic acid 0.1%, methyl hydroxybenzoate 0.01%, Phenoxyethanol 0.01%, essence 0.0015% and water 68.8785%.
Preparation method is with reference to embodiment 1.
Comparative example 2,
Formula：It is made of the raw material of following weight percent meter：Butanediol 6%, dimethyl silicone polymer 9%, polyglutamic acid
Sodium 2%, glycerine 2%, propylene glycol 1.5%, Natrulon H-10 1.5%, dipropylene glycol 1%, hydroxy-ethyl acrylate/acryloyldimethyl ox
Sodium sulfonate copolymers 1%, xylitol 1.8%, C20-22 alcohol phosphate/C20-22 alcohol 1.6%, Bacillus acidi lactici/pomegranate fruit fermentation production
Object extract 0.5%, arctic Ascophyllum nodosum elite 0.6%, starfish elite 0.5%, hexapeptide -3 0.6%, flores aurantii elite 0.5%, gentian
Extract 0.5%, ursin 0.3%, milk protein 0.2%, methyl hydroxybenzoate 0.01%, Phenoxyethanol 0.01%, 0.0015% and of essence
Water 68.8785%.
Preparation method is with reference to embodiment 1.
Test example one, Product Safety evaluation（Human skin patch is tested）
First, trial target：The anti-wrinkle essence that embodiment 1 ~ 5, comparative example 1 ~ 2 are prepared
Tested crowd's number：70 people, women
Age：Between 30 ~ 50 years old
Health status：Subjects skin's health, no skin disease allergies meet subject and volunteer inclusion criteria.
Grouping：7 groups, every group of 10 people, average age 28 ± 2 years old.
2nd, patch method：Select qualified spot examination device, with closed patch experiment method, by tested material about 0.020mL ~
For 0.025mL drops in spot examination device, external application special adhesive tape is covered on subject back, 24 it is small when after remove tested material, remove respectively
Dermoreaction is observed when 0.5,6,12,24,48 is small afterwards, according to《Cosmetics health specification》Middle dermoreaction grade scale records it
As a result.
3rd, experimental result：Human skin patch the results show：Each group subject by embodiment 1 ~ 5, comparative example 1 ~
The patch test of 2 anti-wrinkle essence observes dermoreaction when 0.5,6,12,24,48 is small, wherein 0 skin occur bad
Reaction illustrates that the anti-wrinkle essence is safe to use.
Test example two, product effect assessment
First portion：
First, trial target：The anti-wrinkle essence that embodiment 1 is prepared
2nd, tested crowd
Gender number：Female, 30 people
Age：Between 35 ~ 45 years old
Health status：Subjects skin's health, no skin disease allergies meet subject and volunteer inclusion criteria.
3rd, test method：Using German Courage+Khazaka companies（German CK companies）The skin elasticity of manufacture
CotometerMPA580 hosts, used probe is Reviscometer RV600 elastic fibrous tissues test probe, surveys five
It is secondary to be averaged.Test zone：Place between the eyebrows middle up 2cm foreheads region, lower lip middle 2cm chin areas, nose down
Point and left and right cheek region at pupil intersection.The blank value of 30min after the tested region clean of first measurement（R2、R5、R7）, so
Regulation subject adheres to sooner or later daily using above-mentioned trial target afterwards, test zone skin after testing 1 week, 2 weeks, 3 weeks, 4 weeks respectively
Elasticity indexes R2, R5, R7 value（It is 450mbar that negative pressure is constant in test process）.
Index explanation：For skin elasticity index R2, R5, R7 closer to 1, the elasticity of skin is better.
R2=Ua/Uf；R5 = Ur/Ue；R7=Ur/Uf
Uf --- skin maximum tension amount
Ue --- after constant negative pressure is added on skin, the amount of tension of skin, positioning elastic part amount of tension at 0.1 second.
Ur --- after cancelling negative pressure, skin will restore to the original state rapidly state, equally be divided into elastic portion score value Ur, that is, cancel negative
Pressure is after 0.1 second, the recovery value and visco-elastic portions value or plastic value of skin.
Ua --- from cancellation negative pressure to the recovery value of skin when follow-on test skin surface adds negative pressure again next time.
4th, test result such as the following table 1.
1 embodiment of table, 1 anti-wrinkle essence test result table
From upper table 1：Using the anti-wrinkle essence of embodiment 1, R2, R5, R7 increased after a week, the 4th week
R2, R5, R7 rise substantially, and R2, R5, R7 value level off to 1, and the skin elasticity index of subject has very big promotion, by
This increases skin elasticity, anti-aging function as it can be seen that this anti-wrinkle essence has.
Second portion：
First, trial target：Anti-wrinkle essence prepared by embodiment 1 ~ 5, comparative example 1 ~ 2
2nd, tested crowd
Gender number：Female, 210 people
Age：Between 35 ~ 55 years old
Health status：Subjects skin's health, no skin disease allergies meet subject and volunteer inclusion criteria.
Grouping：It is divided into 7 groups, every group of 30 people, average age 43 ± 2 years old.
3rd, test method：Respectively using example 1 ~ 5, the anti-wrinkle essence prepared by comparative example 1 ~ 2, observation and impression make
Use effect.Application method：After subject cleans face, appropriate above-mentioned anti-wrinkle essence is taken uniformly to be applied to face in the centre of the palm,
And absorption is gently massaged into, and it is each using once, adhering to using one month daily morning and evening, at least check once whether there is to understand weekly
Whole body and local adverse reaction, and result is recorded in detail.
4th, it is as follows to test assessment result：
2 embodiment of table, 1 anti-wrinkle essence is tried out（One month）Feed back conclusive table
3 embodiment of table, 2 anti-wrinkle essence is tried out（One month）Feed back conclusive table
4 embodiment of table, 3 anti-wrinkle essence is tried out（One month）Feed back conclusive table
5 embodiment of table, 4 anti-wrinkle essence is tried out（One month）Feed back conclusive table
6 embodiment of table, 5 anti-wrinkle essence is tried out（One month）Feed back conclusive table
7 comparative example of table, 1 anti-wrinkle essence is tried out（One month）Feed back conclusive table
8 comparative example of table, 2 anti-wrinkle essence is tried out（One month）Feed back conclusive table
（1）From upper table 2 ~ 6, anti-wrinkle essence the liking and approving by subject of the embodiment of the present invention 1 ~ 5, by
Examination person represents anti-wrinkle essence good penetrability of the present invention, easily absorbs, moisturizing, moistening effect clearly not sticky using rear face
It is good, nutrition is fed to skin, promotes skin metabolism, effectively calms down microgroove, reduce wrinkle, slowing down skin aging, and it is long-acting
Moisturizing makes skin water profit smooth, flexible.With the degree of recognition highest of 1 anti-wrinkle essence of embodiment in embodiment 1 ~ 5, therefore in fact
Example 1 is applied as preferred embodiment.
（2）From upper table 7 ~ 8, comparative example 1 and 2 Essence of comparative example lack certain in re-surface intensive wrinkle correct formula of liquid of the present invention
A little components, using effect not as good as embodiment 1 ~ 5, illustrate letter of the re-surface intensive wrinkle correct formula of liquid of the present invention not by each component
What single group was closed, further illustrate there is synergistic effect between inventive formulation each component.
There is allergic phenomena in non-someone in whole subjects simultaneously, does not also occur the shapes such as pruitus, shouting pain, redness
Condition.Therefore, anti-wrinkle essence of the present invention is mildly safe, can long-time service.
The above-described embodiments merely illustrate the principles and effects of the present invention, and is not intended to limit the present invention.It is any ripe
Know the personage of this technology all can carry out modifications and changes under the spirit and scope without prejudice to the present invention to above-described embodiment.Cause
This, those of ordinary skill in the art is complete without departing from disclosed spirit and institute under technological thought such as
Into all equivalent modifications or change, should by the present invention claim be covered.
Claims (5)
1. a kind of anti-wrinkle essence, which is characterized in that be made of the raw material of following weight percent meter：Cyclomethicone
4 ~ 10%, butanediol 4 ~ 10%, dimethyl silicone polymer 2 ~ 8%, polyglutamic acid sodium 1 ~ 5%, glycerine 0.5 ~ 4%, propylene glycol 0.5 ~ 4%,
Natrulon H-10 0.5 ~ 4%, dipropylene glycol 0.5 ~ 4%, erythrite 0.5 ~ 4%, hydroxy-ethyl acrylate/acryloyldimethyl taurine
Sodium copolymer 0.5 ~ 4%, biological carbohydrate gum -1 0.5 ~ 3%, xylitol 0.5 ~ 3%, C20-22 alcohol phosphate/C20-22 alcohol 0.5 ~ 3%,
Bacillus acidi lactici/pomegranate fruit tunning extract 0.3 ~ 2%, arctic Ascophyllum nodosum elite 0.3 ~ 2%, starfish elite 0.3 ~ 2%, hexapeptide-
3 0.3 ~ 2%, flores aurantii elite 0.3 ~ 2%, rough gentian root extract 0.3 ~ 2%, ursin 0.1 ~ 1%, milk protein 0.1 ~ 1%, tranexamic acid
0.05 ~ 1%, methyl hydroxybenzoate 0.01 ~ 0.1%, Phenoxyethanol 0.01 ~ 0.1%, essence 0.0002 ~ 0.05% and water 40 ~ 70%.
2. anti-wrinkle essence as described in claim 1, which is characterized in that be made of the raw material of following weight percent meter：Ring
Dimethyl silicone polymer 4 ~ 8%, butanediol 4 ~ 8%, dimethyl silicone polymer 2 ~ 6%, polyglutamic acid sodium 1 ~ 4%, glycerine 0.5 ~ 3%, third
Glycol 0.5 ~ 3%, Natrulon H-10 0.5 ~ 3%, dipropylene glycol 0.5 ~ 2%, erythrite 0.5 ~ 2%, hydroxy-ethyl acrylate/acryloyl two
N-methyltaurine sodium copolymer 0.5 ~ 2%, biological carbohydrate gum -1 0.5 ~ 1.5%, xylitol 0.5 ~ 1.5%, C20-22 alcohol phosphate/
C20-22 alcohol 0.5 ~ 1.5%, Bacillus acidi lactici/pomegranate fruit tunning extract 0.3 ~ 1%, arctic Ascophyllum nodosum elite 0.3 ~ 1%, sea
Star elite 0.3 ~ 1%, hexapeptide -3 0.3 ~ 1%, flores aurantii elite 0.3 ~ 1%, rough gentian root extract 0.3 ~ 1%, ursin 0.1 ~ 0.6%,
Milk protein 0.1 ~ 0.6%, tranexamic acid 0.05 ~ 0.3%, methyl hydroxybenzoate 0.01 ~ 0.05%, Phenoxyethanol 0.01 ~ 0.05%, essence
0.0002 ~ 0.01% and water 60 ~ 70%.
3. anti-wrinkle essence as claimed in claim 2, which is characterized in that be made of the raw material of following weight percent meter：Ring
It is dimethyl silicone polymer 6%, butanediol 6%, dimethyl silicone polymer 3%, polyglutamic acid sodium 2%, glycerine 2%, propylene glycol 1.5%, poly-
Glycerine -10 1.5%, dipropylene glycol 1%, erythrite 1%, hydroxy-ethyl acrylate/sodium acryloyldimethyl taurate copolymers 1%, life
Object carbohydrate gum -1 0.8%, xylitol 0.8%, C20-22 alcohol phosphate/C20-22 alcohol 0.8%, Bacillus acidi lactici/pomegranate fruit tunning
Extract 0.5%, arctic Ascophyllum nodosum elite 0.6%, starfish elite 0.5%, hexapeptide -3 0.6%, flores aurantii elite 0.5%, gentian carry
Take object 0.5%, ursin 0.2%, milk protein 0.2%, tranexamic acid 0.1%, methyl hydroxybenzoate 0.01%, Phenoxyethanol 0.01%, essence
0.0015% and water 68.8785%.
4. the preparation method of a kind of anti-wrinkle essence as described in claim 1 ~ 3 is any, which is characterized in that including following step
Suddenly：
S1, by cyclomethicone, dimethyl silicone polymer and C20-22 alcohol phosphate/C20-22 alcohol, add in oil phase pot
In, 80 ~ 85 DEG C are heated to, stirs to being completely dissolved, obtains material A；
S2, Jiang Shui, butanediol, polyglutamic acid sodium, glycerine, propylene glycol, Natrulon H-10, dipropylene glycol, erythrite, xylitol, bear
Fruit glycosides and methyl hydroxybenzoate are added in water phase pot, are heated to 80 ~ 85 DEG C, are stirred to being completely dissolved, are obtained material B；
S3, material A and material B are pumped into emulsification pot, open homogeneous, 5 ~ 10min of homogeneous, 10 ~ 20min of insulated and stirred；
S4,40 ~ 45 DEG C are cooled to, add in hydroxy-ethyl acrylate/sodium acryloyldimethyl taurate copolymers, biological carbohydrate gum -1,
Bacillus acidi lactici/pomegranate fruit tunning extract, arctic Ascophyllum nodosum elite, starfish elite, hexapeptide -3, flores aurantii elite, gentian
Extract, milk protein, tranexamic acid, Phenoxyethanol and essence, stir evenly, you can anti-wrinkle essence is made in discharging.
5. the preparation method of anti-wrinkle essence as claimed in claim 4, which is characterized in that the mixing speed of the stirring is 40
~50 r/min。
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510673049.8A CN105125476B (en) | 2015-10-19 | 2015-10-19 | A kind of anti-wrinkle essence and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510673049.8A CN105125476B (en) | 2015-10-19 | 2015-10-19 | A kind of anti-wrinkle essence and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN105125476A CN105125476A (en) | 2015-12-09 |
| CN105125476B true CN105125476B (en) | 2018-06-05 |
Family
ID=54711308
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510673049.8A Active CN105125476B (en) | 2015-10-19 | 2015-10-19 | A kind of anti-wrinkle essence and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105125476B (en) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106074210B (en) * | 2016-07-18 | 2019-03-01 | 湖南御家化妆品制造有限公司 | Cosmetic composition, application thereof and cosmetic essence |
| CN106176459A (en) * | 2016-08-29 | 2016-12-07 | 秦艳红 | A kind of anti-wrinkle essence |
| MY196008A (en) * | 2016-09-28 | 2023-03-06 | Amorepacific Corp | Composition of Anti-Aging External Application Skin Preparation, Containing Cyanidin-3-O-Glucoside and Natto Gum as Active Ingredients |
| CN106727231A (en) * | 2016-12-22 | 2017-05-31 | 广州睿森生物科技有限公司 | A kind of antipollution composition and cosmetics |
| CN106726799A (en) * | 2017-01-03 | 2017-05-31 | 广州科玛生物科技股份有限公司 | A kind of fair-skinned profit moisturizer and preparation method thereof |
| CN106860232A (en) * | 2017-01-18 | 2017-06-20 | 长沙协浩吉生物工程有限公司 | A kind of compound method of ferment antiallergy Essence |
| CN107308028A (en) * | 2017-04-01 | 2017-11-03 | 上海乐谷娜生物科技有限公司 | Cutaneous penetration essence |
| CN106726654B (en) * | 2017-04-06 | 2017-12-12 | 湖南御家化妆品制造有限公司 | A kind of xylitol moisture-keeping composition and its application in cosmetics |
| CN107281036A (en) * | 2017-07-25 | 2017-10-24 | 广州铭心化妆品有限公司 | Shining color essence cream of one kind and preparation method thereof |
| CN107198662A (en) * | 2017-07-25 | 2017-09-26 | 广州铭心化妆品有限公司 | A kind of beautiful face essence cream and preparation method thereof |
| CN107375018B (en) * | 2017-08-07 | 2024-03-08 | 上海柏悦年轻医疗科技集团有限公司 | Facial massage essence and preparation method thereof and beauty Yan Anma instrument |
| CN108042425B (en) * | 2017-12-27 | 2020-12-22 | 上海晓美生物科技有限公司 | Whitening and moisturizing essence and preparation method thereof |
| CN110051572B (en) * | 2018-01-19 | 2022-03-15 | 百岳特生物科技（上海）有限公司 | Pomegranate fermentation product and use thereof |
| CN108245458A (en) * | 2018-03-28 | 2018-07-06 | 广州科玛大健康产业有限公司 | It is a kind of to repair tender skin lotion and preparation method thereof |
| CN108721162A (en) * | 2018-06-01 | 2018-11-02 | 广州锦同生物科技有限公司 | A kind of smooth essence breast of agalloch eaglewood and preparation method thereof |
| CN108852977B (en) * | 2018-08-28 | 2021-08-24 | 广州科玛生物科技股份有限公司 | Crystal moistening essence |
| CN108904436B (en) * | 2018-09-16 | 2021-09-24 | 韩后化妆品股份有限公司 | Anti-pollution skin care composition with anti-inflammatory and anti-aging effects |
| CN109316360A (en) * | 2018-10-10 | 2019-02-12 | 广州雷诺生物科技有限公司 | A kind of fullerene intensively lifts Essence |
| CN109431950A (en) * | 2018-11-12 | 2019-03-08 | 宁波蒙曼生物科技有限公司 | A kind of anti-wrinkle face mask liquid and preparation method thereof |
| CN109431964A (en) * | 2018-12-29 | 2019-03-08 | 吕飞 | Assign maintenance essence cream living and preparation method thereof in flesh source |
| CN109602665A (en) * | 2019-01-31 | 2019-04-12 | 广州艾蓓生物科技有限公司 | A kind of anti-oxidant Essence |
| CN111214417A (en) * | 2020-03-10 | 2020-06-02 | 广州澳特朗生物技术有限公司 | Yeast essence with effects of tightening and resisting wrinkles and preparation method and application thereof |
| CN111773126A (en) * | 2020-08-11 | 2020-10-16 | 广州市轩颜化妆品有限公司 | Essence for face staying up all night and preparation method thereof |
| CN112220717A (en) * | 2020-10-16 | 2021-01-15 | 清远市华宝生物科技有限公司 | Whitening anti-allergy anti-wrinkle cream and preparation method thereof |
| CN112603874A (en) * | 2020-12-24 | 2021-04-06 | 上海懿林生物科技股份有限公司 | Formula for improving skin nutrition absorption and preparation method thereof |
| CN113384486A (en) * | 2021-06-11 | 2021-09-14 | 张家明 | Anti-wrinkle essence and preparation method thereof |
| CN113413335B (en) * | 2021-07-26 | 2022-08-23 | 广州药妆日用化工有限公司 | Extract containing algae essence, preparation method thereof and prepared moisturizing emulsion |
| CN115040463A (en) * | 2022-06-18 | 2022-09-13 | 山东博科医用材料有限公司 | Anti-wrinkle whitening composition |
| CN115317425A (en) * | 2022-09-02 | 2022-11-11 | 广东丸美生物技术股份有限公司 | Eye essence and preparation method thereof |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102793656A (en) * | 2012-08-10 | 2012-11-28 | 彭再辉 | Firming anti-wrinkle essence cosmetic and preparation method |
| CN104352418A (en) * | 2014-10-20 | 2015-02-18 | 东莞市阿比亚能源科技有限公司 | Anti-ageing essence |
| CN104622907A (en) * | 2013-11-14 | 2015-05-20 | 百岳特生物科技（上海）有限公司 | Use of starfish extract for preparing composition for promoting collagen proliferation |
| CN104814898A (en) * | 2015-05-13 | 2015-08-05 | 朱敏 | Lifting and tightening mask solution, manufacturing method and lifting and tightening mask |
-
2015
- 2015-10-19 CN CN201510673049.8A patent/CN105125476B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102793656A (en) * | 2012-08-10 | 2012-11-28 | 彭再辉 | Firming anti-wrinkle essence cosmetic and preparation method |
| CN104622907A (en) * | 2013-11-14 | 2015-05-20 | 百岳特生物科技（上海）有限公司 | Use of starfish extract for preparing composition for promoting collagen proliferation |
| CN104352418A (en) * | 2014-10-20 | 2015-02-18 | 东莞市阿比亚能源科技有限公司 | Anti-ageing essence |
| CN104814898A (en) * | 2015-05-13 | 2015-08-05 | 朱敏 | Lifting and tightening mask solution, manufacturing method and lifting and tightening mask |
Also Published As
| Publication number | Publication date |
|---|---|
| CN105125476A (en) | 2015-12-09 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN105125476B (en) | A kind of anti-wrinkle essence and preparation method thereof | |
| CN105147590B (en) | A kind of anti-wrinkle eye cream and preparation method thereof | |
| CN105147591B (en) | A kind of crease-resistant face cream and preparation method thereof | |
| CN105168112B (en) | A kind of crease-resistant toner and preparation method thereof | |
| CN105250184B (en) | A kind of whitening anti-aging Essence and preparation method thereof | |
| CN109106664A (en) | Have effects that moisturizing is releived the composition of maintenance, facial mask and preparation method thereof | |
| CN111658818A (en) | Medical repair dressing and application thereof | |
| CN105287340B (en) | A kind of skin whitening, moisturizing eye cream and preparation method thereof | |
| CN113576975B (en) | Easily-absorbed anti-aging composition and preparation method and application thereof | |
| CN108836919B (en) | Moisturizing cosmetic composition and preparation method and application thereof | |
| CN107714559A (en) | One kind is without anti-corrosion deep water supplement skin care item | |
| CN107496310A (en) | A kind of facial treatment essence liquid and preparation method thereof | |
| CN107496316A (en) | A kind of face cream and preparation method thereof | |
| CN106074304A (en) | A kind of containing hyaluronate sodium microsphere and the anti-aging cosmetics compositions with smooth out wrinkles, even skin effect of peptide | |
| CN113786379A (en) | Lactic acid bacteria whitening and repairing essence and preparation method thereof | |
| CN111012691A (en) | Medical cold compress wainscot membrane | |
| CN112043619B (en) | Peptide composition with repairing effect and preparation method and application thereof | |
| CN102836093A (en) | Facial cream containing type I collagen | |
| CN109528592A (en) | Facial mask and preparation method thereof is repaired in a kind of moisturizing whitening | |
| CN106309260B (en) | A kind of Radix Notoginseng is preserved youthful looks facial mask | |
| CN107753357A (en) | Toning lotion containing stem cell secretion factors | |
| CN114712285A (en) | Composition with anti-wrinkle effect and preparation method and application thereof | |
| CN109431853A (en) | A kind of reparation facial mask and its production technology | |
| CN113768853A (en) | Whitening and spot-fading composition as well as preparation method and application thereof | |
| CN113368003A (en) | Composition with overnight muscle repairing effect and preparation method and application thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| CB02 | Change of applicant information |
Address after: Huadu District, Guangdong city of Guangzhou province 510880 Flower Town Qiyuan Road No. 28 Applicant after: Guangzhou Kema biotechnology Polytron Technologies Inc Address before: Hua Town, Huadu District, Guangdong Province, 510880 Avenue, Guangzhou City Applicant before: Kerma (unit of kinetic energy) bio tech ltd, Guangzhou |
|
| CB02 | Change of applicant information | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |