CN106177878A - A kind of pharmaceutical composition promoting growing-finishing pigs and raising immune performance and preparation method thereof - Google Patents
A kind of pharmaceutical composition promoting growing-finishing pigs and raising immune performance and preparation method thereof Download PDFInfo
- Publication number
- CN106177878A CN106177878A CN201610771916.6A CN201610771916A CN106177878A CN 106177878 A CN106177878 A CN 106177878A CN 201610771916 A CN201610771916 A CN 201610771916A CN 106177878 A CN106177878 A CN 106177878A
- Authority
- CN
- China
- Prior art keywords
- parts
- fructus
- radix
- citri reticulatae
- rhizoma
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
- Fodder In General (AREA)
Abstract
The invention belongs to technical field of animal remedy preparation.Disclose a kind of pharmaceutical composition promoting growing-finishing pigs and raising immune performance and preparation method thereof.Described pharmaceutical composition includes Ramulus Cinnamomi, Radix Glycyrrhizae, Rhizoma Zingiberis, Pericarpium Citri Reticulatae, the Rhizoma Atractylodis Macrocephalae, Fructus Crataegi, Rhizoma Alpiniae Officinarum, Pericarpium Zanthoxyli, Pericarpium Citri Reticulatae Viride, Fructus Aurantii Immaturus, Fructus Evodiae, Flos Caryophylli, Herba Asari, Rhizoma Atractylodis, Radix Codonopsis, Radix Bupleuri, Fructus Jujubae, the Radix Paeoniae Alba, Fructus Schisandrae Chinensis and Radix Salviae Miltiorrhizae.Preparation method is to be cleaned respectively by medical material, weigh, and is ground into coarse powder, adds the water extraction of 15 times amount, concentrates, and dried extract, by extract mixing and stirring.Animal experiment shows, the present invention can promote growing-finishing pigs, improves carcass trait, improves immunity.
Description
Technical field
The invention belongs to technical field of animal remedy preparation.It is specifically related to a kind of promote growing-finishing pigs and improve immune performance
Pharmaceutical composition and preparation method thereof, this medicine is primarily to facilitate growing-finishing pigs, improves carcass trait, improves immunity.
Background technology
Along with scientific research deeply develops, find that the use of medical feed additive produces various negative effects.Expert refers to
Going out, there are the problems such as drug resistance, drug residue in life-time service antibiotics feed additive, serious threat human health,
Its Excreta also can cause environmental pollution.Additionally cause dysbacteriosis, poultry autogenous infection and superinfection etc..Many states
Family prohibites or limits the use of antibiotic feed additive, and healthy aquaculture becomes necessarily becoming of whole world aquaculture industry development
Gesture.On the other hand, China's industry of raising pigs is fast-developing, and Carnis Sus domestica yield increases, and meat quality declines；Simultaneously along with Living Water
Flat raising, the prescription of pork product is also improved constantly by people, and green safety food becomes generally to be pursued.Therefore peace is sought
Complete free of contamination novel fodder additive becomes study hotspot.
Research shows, Chinese herbal medicine contains abundant nutrient substance and biological active substances, can improve growth of animal and produce
Performance；Improve intestinal health；Facilitating digestion absorbs；Strengthen immunity, antibacterial, antiviral；Improve product quality, be considered to have
The green feed additive of development potentiality.The growing and fattening pigs stage is middle growth rate the fastest stage of raising pigs, and controlling this stage well can
To quickly promote its growth promoter, increase economic efficiency.Pharmaceutical composition of the present invention has pure natural source, safe and harmless, poison
The advantages such as side effect is little, composition diverse in function, environmental protection and economy, can promote that growing-finishing pigs grows performance, improve carcass quality,
Improve immunity.
Summary of the invention
It is an object of the invention to the drug resistance overcoming abuse of antibiotics to cause, drug residue, dysbacteriosis, endogenous sexuality
Dye, degradation negative issue under immunity of livestock, it is provided that a kind of safe and harmless, toxic and side effects is little, the pharmaceutical composition of environmental protection and economy
And preparation method thereof, to promote growing-finishing pigs, improve carcass trait, enhancing immunity.According to tcm theory, its crude drug
Including Ramulus Cinnamomi, Radix Glycyrrhizae, Rhizoma Zingiberis, Pericarpium Citri Reticulatae, the Rhizoma Atractylodis Macrocephalae, Fructus Crataegi, Rhizoma Alpiniae Officinarum, Pericarpium Zanthoxyli, Pericarpium Citri Reticulatae Viride, Fructus Aurantii Immaturus, Fructus Evodiae, Flos Caryophylli, Herba Asari, grey
Art, Radix Codonopsis, Radix Bupleuri, Fructus Jujubae, the Radix Paeoniae Alba, Fructus Schisandrae Chinensis, Radix Salviae Miltiorrhizae.
Ramulus Cinnamomi: diaphoresis expelling pathogenic factors from muscles, promoting the flow of QI-blood by warming the meridian, supporing yang activating QI, the flat gas that spins.For anemofrigid cold, cold in blood amenorrhea, joint numbness
Bitterly, cardiopalmus.
Radix Glycyrrhizae: invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, cushion toxicity, strong
Property.
Rhizoma Zingiberis: warming spleen and stomach for dispelling cold, recuperating depleted YANG promotes blood circulation, warming the lung to resolve fluid-retention.For cold extremities faint pulse, cold fluid-retention is breathed with cough.
Pericarpium Citri Reticulatae: regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm.For lack of appetite and vomiting, distension and fullness in the abdomen.
The Rhizoma Atractylodis Macrocephalae: invigorating the spleen and benefiting QI, dampness diuretic.For insufficiency of the spleen lack of appetite, phlegm retention vertigo and palpitation.
Fructus Crataegi: promoting digestion and invigorating the stomach, circulation of qi promoting dissipating blood stasis, change turbid blood fat reducing.For meat stagnation, gastral cavilty distension, obstruction of qi in the chest and cardialgia, hyperlipemia
Disease.
Rhizoma Alpiniae Officinarum: stomach warming preventing or arresting vomiting, dispersing cold for relieving pain.For coldness and pain in the epigastrium, gastrofrigid vomiting.
Pericarpium Zanthoxyli: warming middle-JIAO to relieve pain, killing parasites for relieving itching.For abdominal pain due to worm stagnation, external treatment eczema.
Pericarpium Citri Reticulatae Viride: soothing the liver dispelling the stagnated QI, removing food stagnancyization is stagnant.For hernia pain, stagnation of QI due to dyspepsia.
Fructus Aurantii Immaturus: dispelling the stagnated QI removing food stagnancy, scattered painful abdominal mass of reducing phlegm.Stop in stagnant, the stagnant vapour lock of expectorant.
Fructus Evodiae: supporing yang antidiarrheal, stopping nausea and vomiting by lowering the adverse flow of QI.For headache due to JUE YIN disorder, colic of cold type is suffered from abdominal pain, Diarrhoea.
Flos Caryophylli: warming middle-JIAO to send down the adverse QI, reinforcing the kidney and supporting YANG.For Deficiency and coldness of spleen and stomach, lack of appetite and vomiting.
Herba Asari: relieving exterior syndrome and dispelling cold, wind-expelling pain-stopping.For anemofrigid cold, rheumatic arthralgia, phlegm retention is breathed with cough.
Rhizoma Atractylodis: drying damp and strengthening spleen, expelling wind and cold.For retention of dampness in middle-JIAO, rheumatic arthralgia, anemofrigid cold, eyes dusk is puckery.
Radix Codonopsis: strengthening spleen and tonifying lung, nourishing blood to promote the production of body fluid.For deficiency of both the splenic and pulmonary QI, lack of appetite asthenia, dyspnea due to deficiency of coughing, insufficiency of vital energy and blood, cardiopalmus gas
Short, Tianjin wound is thirsty, and interior-heat is quenched one's thirst.
Radix Bupleuri: evacuate and bring down a fever, dispersing the stagnated live-QI to relieve the stagnation of QI, rise and lift yang-energy.For alternate attack of chill and fever, distending pain in the chest and hypochondrium.
Fructus Jujubae: invigorating the spleen and replenishing QI, nourishing blood to tranquillize the mind.For insufficiency of the spleen lack of appetite, weak loose stool.
The Radix Paeoniae Alba: astringing YIN to stop sweating, easing the affected liver to relieve pain, suppressing liver-YANG.For night sweat, hypochondriac pain, blood deficiency and yellow complexion, dizziness of having a headache.
Fructus Schisandrae Chinensis: restrain astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid, kidney calming.For chronic cough dyspnea due to deficiency, incessant chronic diarrhea, Tianjin wound is thirsty, interior-heat
Quench one's thirst, palpitation and insomnia.
Radix Salviae Miltiorrhizae: blood circulation promoting and blood stasis dispelling, clear away heart-fire relieving restlessness, removing heat from blood eliminating carbuncle.For obstruction of qi in the chest and cardialgia, pyretic arthralgia pain, dysphoria and insomnia.
The present invention is realized by techniques below method:
A kind of pharmaceutical composition promoting growing-finishing pigs and improving immune performance, by the raw material system of following parts by weight
Become: Ramulus Cinnamomi 10-20 part, Radix Glycyrrhizae 10-20 part, Rhizoma Zingiberis 5-15 part, Pericarpium Citri Reticulatae 15-25 part, Rhizoma Atractylodis Macrocephalae 15-25 part, Fructus Crataegi 10-20 part, height
Rhizoma Alpiniae Officinarum 5-15 part, Pericarpium Zanthoxyli 10-20 part, Pericarpium Citri Reticulatae Viride 10-20 part, Fructus Aurantii Immaturus 10-20 part, Fructus Evodiae 10-20 part, Flos Caryophylli 10-20 part, Herba Asari
5-15 part, Rhizoma Atractylodis 10-20 part, Radix Codonopsis 10-20 part, Radix Bupleuri 10-20 part, Fructus Jujubae 5-15 part, Radix Paeoniae Alba 10-20 part, Fructus Schisandrae Chinensis 10-20
Part, Radix Salviae Miltiorrhizae 10-20 part.
The present invention is realized by techniques below method:
A kind of pharmaceutical composition promoting growing-finishing pigs and improving immune performance, by the raw material system of following parts by weight
Become: Ramulus Cinnamomi 13-17 part, Radix Glycyrrhizae 13-17 part, Rhizoma Zingiberis 8-12 part, Pericarpium Citri Reticulatae 18-22 part, Rhizoma Atractylodis Macrocephalae 18-22 part, Fructus Crataegi 13-17 part, height
Rhizoma Alpiniae Officinarum 8-12 part, Pericarpium Zanthoxyli 13-17 part, Pericarpium Citri Reticulatae Viride 13-17 part, Fructus Aurantii Immaturus 13-17 part, Fructus Evodiae 13-17 part, Flos Caryophylli 13-17 part, Herba Asari
8-12 part, Rhizoma Atractylodis 13-17 part, Radix Codonopsis 13-17 part, Radix Bupleuri 13-17 part, Fructus Jujubae 8-12 part, Radix Paeoniae Alba 13-17 part, Fructus Schisandrae Chinensis 13-17
Part, Radix Salviae Miltiorrhizae 13-17 part.
The present invention is realized by techniques below method:
A kind of pharmaceutical composition promoting growing-finishing pigs and improving immune performance, by the raw material system of following parts by weight
Become: Ramulus Cinnamomi 15 parts, 15 parts of Radix Glycyrrhizae, Rhizoma Zingiberis 10 parts, Pericarpium Citri Reticulatae 20 parts, the Rhizoma Atractylodis Macrocephalae 20 parts, Fructus Crataegi 15 parts, Rhizoma Alpiniae Officinarum 10 parts, 15 parts of Pericarpium Zanthoxyli,
15 parts of Pericarpium Citri Reticulatae Viride, Fructus Aurantii Immaturus 15 parts, Fructus Evodiae 15 parts, Flos Caryophylli 15 parts, Herba Asari 10 parts, Rhizoma Atractylodis 15 parts, Radix Codonopsis 15 parts, Radix Bupleuri 15 parts, big
Fructus Jujubae 10 parts, the Radix Paeoniae Alba 15 parts, Fructus Schisandrae Chinensis 15 parts, Radix Salviae Miltiorrhizae 15 parts.
A kind of pharmaceutical composition promoting growing-finishing pigs and improving immune performance, is made up of following methods:
(1) by Ramulus Cinnamomi, Radix Glycyrrhizae, Rhizoma Zingiberis, Pericarpium Citri Reticulatae, the Rhizoma Atractylodis Macrocephalae, Fructus Crataegi, Rhizoma Alpiniae Officinarum, Pericarpium Zanthoxyli, Pericarpium Citri Reticulatae Viride, Fructus Aurantii Immaturus, Fructus Evodiae, Flos Caryophylli,
Herba Asari, Rhizoma Atractylodis, Radix Codonopsis, Radix Bupleuri, Fructus Jujubae, the Radix Paeoniae Alba, Fructus Schisandrae Chinensis, red rooted salvia are cleaned, dry, are weighed, and are ground into coarse powder；
(2) medicinal material coarse powder is added the water of 1-5 times, is heated to boiling, is allowed to the 1-5h that seethes with excitement, extract 1-5 time every time, backflow
To extractum, it is vacuum dried into powder and obtains extract；
(3) above extract is mixed, stir 10-20min.
Beneficial effects of the present invention is as follows:
1, traditional Chinese medicine theory is combined by the present invention with modern production, extracts product to greatest extent and effectively becomes
Point.
2, the present invention can promote growing-finishing pigs, improves carcass trait, enhancing immunity.
3, raw material sources of the present invention are natural, safe and harmless, and toxic and side effects is little, composition diverse in function, environmental protection and economy.
Detailed description of the invention
Below by embodiment, the present invention is elaborated, the most therefore limit the present invention to described embodiment model
Among enclosing.
Embodiment 1
Ramulus Cinnamomi 10 parts, 10 parts of Radix Glycyrrhizae, Rhizoma Zingiberis 5 parts, Pericarpium Citri Reticulatae 15 parts, the Rhizoma Atractylodis Macrocephalae 15 parts, Fructus Crataegi 10 parts, Rhizoma Alpiniae Officinarum 5 parts, Pericarpium Zanthoxyli 10
Part, 10 parts of Pericarpium Citri Reticulatae Viride, Fructus Aurantii Immaturus 10 parts, Fructus Evodiae 10 parts, Flos Caryophylli 10 parts, Herba Asari 5 parts, Rhizoma Atractylodis 10 parts, Radix Codonopsis 10 parts, Radix Bupleuri 10 parts,
5 parts of Fructus Jujubae, the Radix Paeoniae Alba 10 parts, Fructus Schisandrae Chinensis 10 parts, Radix Salviae Miltiorrhizae 10 parts.
Preparation method is as follows:
(1) by Ramulus Cinnamomi, Radix Glycyrrhizae, Rhizoma Zingiberis, Pericarpium Citri Reticulatae, the Rhizoma Atractylodis Macrocephalae, Fructus Crataegi, Rhizoma Alpiniae Officinarum, Pericarpium Zanthoxyli, Pericarpium Citri Reticulatae Viride, Fructus Aurantii Immaturus, Fructus Evodiae, Flos Caryophylli,
Herba Asari, Rhizoma Atractylodis, Radix Codonopsis, Radix Bupleuri, Fructus Jujubae, the Radix Paeoniae Alba, Fructus Schisandrae Chinensis, red rooted salvia are cleaned, dry, are weighed, and are ground into coarse powder；
(2) medicinal material coarse powder is added the water of 1 times, is heated to boiling, is allowed to the 1h that seethes with excitement, extract 1 time every time, be back to leaching
Cream, is vacuum dried into powder and obtains extract；
(3) above extract is mixed, stir 10-20min.
Embodiment 2
Ramulus Cinnamomi 15 parts, 15 parts of Radix Glycyrrhizae, Rhizoma Zingiberis 10 parts, Pericarpium Citri Reticulatae 20 parts, the Rhizoma Atractylodis Macrocephalae 20 parts, Fructus Crataegi 15 parts, Rhizoma Alpiniae Officinarum 10 parts, Pericarpium Zanthoxyli
15 parts, 15 parts of Pericarpium Citri Reticulatae Viride, Fructus Aurantii Immaturus 15 parts, Fructus Evodiae 15 parts, Flos Caryophylli 15 parts, Herba Asari 10 parts, Rhizoma Atractylodis 15 parts, Radix Codonopsis 15 parts, Radix Bupleuri 15
Part, 10 parts of Fructus Jujubae, the Radix Paeoniae Alba 15 parts, Fructus Schisandrae Chinensis 15 parts, Radix Salviae Miltiorrhizae 15 parts.
Preparation method is as follows:
(1) by Ramulus Cinnamomi, Radix Glycyrrhizae, Rhizoma Zingiberis, Pericarpium Citri Reticulatae, the Rhizoma Atractylodis Macrocephalae, Fructus Crataegi, Rhizoma Alpiniae Officinarum, Pericarpium Zanthoxyli, Pericarpium Citri Reticulatae Viride, Fructus Aurantii Immaturus, Fructus Evodiae, Flos Caryophylli,
Herba Asari, Rhizoma Atractylodis, Radix Codonopsis, Radix Bupleuri, Fructus Jujubae, the Radix Paeoniae Alba, Fructus Schisandrae Chinensis, red rooted salvia are cleaned, dry, are weighed, and are ground into coarse powder；
(2) medicinal material coarse powder is added the water of 3 times, is heated to boiling, is allowed to the 3h that seethes with excitement, extract 3 times every time, be back to leaching
Cream, is vacuum dried into powder and obtains extract；
(3) above extract is mixed, stir 10-20min.
Embodiment 3
Ramulus Cinnamomi 20 parts, 20 parts of Radix Glycyrrhizae, Rhizoma Zingiberis 15 parts, Pericarpium Citri Reticulatae 25 parts, the Rhizoma Atractylodis Macrocephalae 25 parts, Fructus Crataegi 20 parts, Rhizoma Alpiniae Officinarum 15 parts, Pericarpium Zanthoxyli
20 parts, 20 parts of Pericarpium Citri Reticulatae Viride, Fructus Aurantii Immaturus 20 parts, Fructus Evodiae 20 parts, Flos Caryophylli 20 parts, Herba Asari 15 parts, Rhizoma Atractylodis 20 parts, Radix Codonopsis 20 parts, Radix Bupleuri 20
Part, 15 parts of Fructus Jujubae, the Radix Paeoniae Alba 20 parts, Fructus Schisandrae Chinensis 20 parts, Radix Salviae Miltiorrhizae 20 parts.
Preparation method is as follows:
(1) by Ramulus Cinnamomi, Radix Glycyrrhizae, Rhizoma Zingiberis, Pericarpium Citri Reticulatae, the Rhizoma Atractylodis Macrocephalae, Fructus Crataegi, Rhizoma Alpiniae Officinarum, Pericarpium Zanthoxyli, Pericarpium Citri Reticulatae Viride, Fructus Aurantii Immaturus, Fructus Evodiae, Flos Caryophylli,
Herba Asari, Rhizoma Atractylodis, Radix Codonopsis, Radix Bupleuri, Fructus Jujubae, the Radix Paeoniae Alba, Fructus Schisandrae Chinensis, red rooted salvia are cleaned, dry, are weighed, and are ground into coarse powder；
(2) medicinal material coarse powder is added the water of 5 times, is heated to boiling, is allowed to the 5h that seethes with excitement, extract 5 times every time, be back to leaching
Cream, is vacuum dried into powder and obtains extract；
(3) above extract is mixed, stir 10-20min.
Embodiment 4 animal experiment of the present invention
1 test material and method
1.1 experimental animal
Selecting the healthy growing and fattening pigs that average weight is 60kg 200, principle close by body weight, male and female half and half is divided at random
It is 4 groups, often 5 repetitions of group, 10 pigs of each repetition.
1.2 EXPERIMENTAL DESIGN
Test is divided into four groups, tests I group and is matched group: feeds basal diet；Test II group and be antibiotic group: feed basis
Daily ration adds 55mg/kg virginiamycin (40%)；Test III group and be pharmaceutical composition group of the present invention: feed basal diet and add
0.5% pharmaceutical composition of the present invention；Testing IV group is pharmaceutical composition group of the present invention: feeds basal diet and adds 1.0% present invention
Pharmaceutical composition.Basal diet preparation prepares (being shown in Table 1) with reference to NRC (1998) growing and fattening pigs nutritional need recommended amounts.
Table 1 daily ration composition and trophic level
Note: premix material provides for every kilogram of daily ration: Riboflavin Tetrabutyrate .5mg；Pantothenic acid 6.8mg；Nicotinic acid 20.3mg；Choline chloride
351mg；Mn 10mg；Fe 50mg；Zn 50mg；Cu 20mg；I 0.3mg；Se 0.3mg；VA 2512IU；VD31200IU；
VE 34IU；VK31.5mg；VB12 17.6ug。
1.3 feeding and management
7 days preliminary trial periods, 30 days formal phases.Feed every day 2 times, freely drink water and search for food.Utensil is periodically sterilized, routinely program
Testing temperature, humidity, carry out immunity.Weigh on an empty stomach to often organizing test pig respectively at day on-test and closing day.After off-test,
Often group is chosen 5 pigs and is cut off the water to stop eating and butcher after 24h.
1.4 testing index
1.4.1 growth performance
Respectively at on-test and at the end of weigh in, calculate average daily ingestion amount, average daily gain, feed-weight ratio, abdomen
Rush down rate, sickness rate.Feed-weight ratio=average daily ingestion amount/average daily gain.
1.4.2 carcass trait
Carcass weight, lean meat percentage, the thickness of backfat, the carcass trait such as dressing percentage is in close relations with economic well-being of workers and staff.Off-test, respectively
Measure carcass trait index.Dressing percentage=(carcass weight/Slaughter weight) × 100%.
1.4.3 immune indexes
Immunoglobulin major function is conjugated antigen, activating complement.IgA, IgG, IgM are immune balls main in serum
Albumen.Complement is primarily involved in protective immune response, maintains body homeostasis.C3 can promote phagocytosis, immune adherence, has
Immunoloregulation function；C4 can participate in regulating complement activation, prevents immune complex from precipitating.Thyroxine has with growth hormone
Synergism, it is possible to promote pig growth and development.
2 result of the tests
2.1 growth performance
Table 2 matched group, antibiotic group, pharmaceutical composition group of the present invention impact on growing-finishing pigs performance respectively
Note: colleague's data shoulder mark same letter or not notable (P > 0.05) without letter representation difference, the different small letter of shoulder mark
Matrix shows significant difference (P < 0.05).Lower same.
As shown in Table 2, add 0.5%, 1.0% pharmaceutical composition group of the present invention compared with matched group, average daily ingestion amount
It is respectively increased 2.03%, 3.66%；Daily gain is respectively increased 2.56%, and 4.56%；Feed-weight ratio declines 0.34% respectively,
0.68%；Diarrhea rate declines 60.17%, 62.24% respectively；Sickness rate declines 66.48%, 69.89% respectively；With antibiotic group
Comparing, average daily ingestion amount is respectively increased 1.21%, and 2.82%；Daily gain is respectively increased 1.95%, and 3.95%；Feed-weight ratio is respectively
Decline 0.68%, 1.01%；Diarrhea rate declines 35.50%, 38.86% respectively；Sickness rate declines 47.84% respectively,
53.14%.
2.2 carcass trait
Table 3 matched group, antibiotic group, pharmaceutical composition group of the present invention impact on growing and fattening pigs carcass trait respectively
As shown in Table 3, interpolation 0.5%, 1.0% pharmaceutical composition group of the present invention is compared with matched group, and carcass weight carries respectively
High by 1.93%, 1.52%；Lean meat percentage is respectively increased 8.88%, and 10.80%；Eye muscle area is respectively increased 0.42%, and 7.0%；The back of the body
Fat thickness reduces by 5.05%, 7.07% respectively；Compared with antibiotic group, carcass weight is respectively increased 0.98%, and 0.58%；Lean meat percentage divides
You can well imagine high by 8.08%, 9.99%；Eye muscle area has been respectively increased 3.99%, and 10.80%；The thickness of backfat reduces by 7.39% respectively,
9.36%.
2.3 immune indexes
Table 4 matched group, antibiotic group, pharmaceutical composition group of the present invention impact on growing and fattening pigs blood parameters respectively
As shown in Table 4, daily ration adds pharmaceutical composition of the present invention, can improve Immunoglobulin in Serum, Complement C_3,
C4, the content of thyroxine FT3, FT4.In daily ration, interpolation 0.5%, 1.0% pharmaceutical composition group of the present invention is compared with matched group,
The concentration of IgA is respectively increased 8.11%, and 37.84%；The concentration of IgG is respectively increased 14.59%, and 16.98%；The concentration of IgM is divided
You can well imagine high by 23.08%, 25%；In serum, the content of Complement C_3 is respectively increased 44.44%, and 55.55%；In serum, Complement C4 contains
Amount is respectively increased 100%, and 125%；3 is respectively increased 28.07%, and 31.58%；Free thyroxine is respectively
Improve 16.90%, 18.52%；Compared with antibiotic group, the concentration of IgA is respectively increased 2.56%, and 30.77%；The concentration of IgG
It is respectively increased 12.79%, 15.14%；The concentration of IgM is respectively increased 18.52%, and 20.37%；In serum, the content of Complement C_3 divides
You can well imagine high by 18.18%, 27.27%；In serum, the content of Complement C4 is respectively increased 60%, and 80%；3 is respectively
Improve 12.31%, 15.38%；Free thyroxine is respectively increased 6.37%, and 7.84%.
Conclusion: compared with matched group and antibiotic group, pharmaceutical composition of the present invention can improve daily ingestion amount, daily gain,
Reducing feed-weight ratio, diarrhea rate, sickness rate, explanation can promote growing-finishing pigs；Pharmaceutical composition of the present invention can improve carcass weight,
Lean meat percentage, eye muscle area, reduce the thickness of backfat, explanation can improve carcass trait；Pharmaceutical composition of the present invention can improve serum
Middle immunoglobulin A, the concentration of G, M, improves Complement C_3 in serum, C4 content, improves thyroxine FT3, the content of FT4, say
Bright can be with enhancing immunity.
Claims (5)
1. promote growing-finishing pigs and improve a pharmaceutical composition for immune performance, being made up of following raw material: Ramulus Cinnamomi
(Cinnamomum cassia Presl), Radix Glycyrrhizae (Glycyrrhiza uralensis Fisch., Glycyrrhiza
Inflata Bat., Glycyrrhiza glabra L.), Rhizoma Zingiberis (Zingiber officinale Rosc.), Pericarpium Citri Reticulatae
(Citrus reticulata Blanco), the Rhizoma Atractylodis Macrocephalae (Atractylodes macrocephala Koidz.), Fructus Crataegi
(Crataegus pinnatifida Bge.var.major N.E.Br., Crataegus pinnatifida Bge.), Gao Liang
Rhizoma Zingiberis Recens (Alpinia officinarum Hance), Pericarpium Zanthoxyli (Zanthoxylum schinifolium Sieb.et Zucc.,
Zanthoxylum bungeanum Maxim.), Pericarpium Citri Reticulatae Viride (Citrus reticulata Blanco), Fructus Aurantii Immaturus (Citrus
Aurantium ' L., Citrus sinensis Osbeck), Fructus Evodiae (Euodia rutaecarpa (Juss.) Benth.,
Euodia rutaecarpa(Juss.)Benth.var.officinalis(Dode)Huang、Euodia rutaecarpa
(Juss.) Benth.var.bodinieri (Dode) Huang), Flos Caryophylli (Eugenia caryophyllata Thunb.), thin
Pungent (Asarum heterotropoides Fr.Schmidt var.mandshuricum (Maxim.) Kitag., Asarum
Sieboldii Miq.var.seoulense Nakai, Asarum sieboldii Miq.), Rhizoma Atractylodis (Atractylodes
Lancea (Thunb.) DC., Atractylodes chinensis (DC.) Koidz.), Radix Codonopsis (Codonopsis pilosula
(Franch.)Nannf.、Codonopsis pilosula Nannf.var.modesta(Nannf.)L.T.Shen、
Codonopsis tangshen Oliv.), Radix Bupleuri (Bupleurum chinense DC., Bupleurum
Scorzonerifolium Willd.), Fructus Jujubae (Ziziphus jujuba Mill.), the Radix Paeoniae Alba (Paeonia lactiflora
Pall.), Fructus Schisandrae Chinensis (Schisandra chinensis (Turcz.) Baill.), Radix Salviae Miltiorrhizae (Salvia miltiorrhiza
Bge.)。
A kind of pharmaceutical composition promoting growing-finishing pigs and improving immune performance the most according to claim 1, by following
The raw material of parts by weight is made: Ramulus Cinnamomi 10-20 part, Radix Glycyrrhizae 10-20 part, Rhizoma Zingiberis 5-15 part, Pericarpium Citri Reticulatae 15-25 part, Rhizoma Atractylodis Macrocephalae 15-25
Part, Fructus Crataegi 10-20 part, Rhizoma Alpiniae Officinarum 5-15 part, Pericarpium Zanthoxyli 10-20 part, Pericarpium Citri Reticulatae Viride 10-20 part, Fructus Aurantii Immaturus 10-20 part, Fructus Evodiae 10-20
Part, Flos Caryophylli 10-20 part, Herba Asari 5-15 part, Rhizoma Atractylodis 10-20 part, Radix Codonopsis 10-20 part, Radix Bupleuri 10-20 part, Fructus Jujubae 5-15 part, the Radix Paeoniae Alba
10-20 part, Fructus Schisandrae Chinensis 10-20 part, Radix Salviae Miltiorrhizae 10-20 part.
A kind of pharmaceutical composition promoting growing-finishing pigs and improving immune performance the most according to claim 2, by following
The raw material of parts by weight is made: Ramulus Cinnamomi 13-17 part, Radix Glycyrrhizae 13-17 part, Rhizoma Zingiberis 8-12 part, Pericarpium Citri Reticulatae 18-22 part, Rhizoma Atractylodis Macrocephalae 18-22
Part, Fructus Crataegi 13-17 part, Rhizoma Alpiniae Officinarum 8-12 part, Pericarpium Zanthoxyli 13-17 part, Pericarpium Citri Reticulatae Viride 13-17 part, Fructus Aurantii Immaturus 13-17 part, Fructus Evodiae 13-17
Part, Flos Caryophylli 13-17 part, Herba Asari 8-12 part, Rhizoma Atractylodis 13-17 part, Radix Codonopsis 13-17 part, Radix Bupleuri 13-17 part, Fructus Jujubae 8-12 part, the Radix Paeoniae Alba
13-17 part, Fructus Schisandrae Chinensis 13-17 part, Radix Salviae Miltiorrhizae 13-17 part.
A kind of pharmaceutical composition promoting growing-finishing pigs and improving immune performance the most according to claim 3, by following
The raw material of parts by weight is made: Ramulus Cinnamomi 15 parts, 15 parts of Radix Glycyrrhizae, Rhizoma Zingiberis 10 parts, Pericarpium Citri Reticulatae 20 parts, the Rhizoma Atractylodis Macrocephalae 20 parts, Fructus Crataegi 15 parts, Gao Liang
Rhizoma Zingiberis Recens 10 parts, 15 parts of Pericarpium Zanthoxyli, 15 parts of Pericarpium Citri Reticulatae Viride, Fructus Aurantii Immaturus 15 parts, Fructus Evodiae 15 parts, Flos Caryophylli 15 parts, Herba Asari 10 parts, Rhizoma Atractylodis 15 parts, Radix Codonopsis
15 parts, Radix Bupleuri 15 parts, 10 parts of Fructus Jujubae, the Radix Paeoniae Alba 15 parts, Fructus Schisandrae Chinensis 15 parts, Radix Salviae Miltiorrhizae 15 parts.
A kind of pharmaceutical composition promoting growing-finishing pigs and improving immune performance the most according to claim 2, by following
Method is made:
(1) by Ramulus Cinnamomi, Radix Glycyrrhizae, Rhizoma Zingiberis, Pericarpium Citri Reticulatae, the Rhizoma Atractylodis Macrocephalae, Fructus Crataegi, Rhizoma Alpiniae Officinarum, Pericarpium Zanthoxyli, Pericarpium Citri Reticulatae Viride, Fructus Aurantii Immaturus, Fructus Evodiae, Flos Caryophylli, thin
Pungent, Rhizoma Atractylodis, Radix Codonopsis, Radix Bupleuri, Fructus Jujubae, the Radix Paeoniae Alba, Fructus Schisandrae Chinensis, red rooted salvia are cleaned, dry, are weighed, and are ground into coarse powder；
(2) medicinal material coarse powder is added the water of 1-5 times, is heated to boiling, is allowed to the 1-5h that seethes with excitement, extract 1-5 time every time, be back to leaching
Cream, is vacuum dried into powder and obtains extract；
(3) above extract is mixed, stir 10-20min.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610771916.6A CN106177878B (en) | 2016-08-30 | 2016-08-30 | A kind of pharmaceutical composition and preparation method thereof for promoting growing-finishing pigs and improving immune performance |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610771916.6A CN106177878B (en) | 2016-08-30 | 2016-08-30 | A kind of pharmaceutical composition and preparation method thereof for promoting growing-finishing pigs and improving immune performance |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN106177878A true CN106177878A (en) | 2016-12-07 |
| CN106177878B CN106177878B (en) | 2019-09-20 |
Family
ID=58088229
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610771916.6A Active CN106177878B (en) | 2016-08-30 | 2016-08-30 | A kind of pharmaceutical composition and preparation method thereof for promoting growing-finishing pigs and improving immune performance |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106177878B (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107242370A (en) * | 2017-06-17 | 2017-10-13 | 申学林 | Sucking pig specific enzyme solution mixed feed |
| CN107596204A (en) * | 2017-10-11 | 2018-01-19 | 安徽省宿州市民辉养殖有限公司 | A kind of medicine for pig health care fattening |
| CN107715034A (en) * | 2017-10-25 | 2018-02-23 | 广西沙田仙人滩农业投资有限公司 | A kind of hawthorn medicine for treating a variety of poultry diseases |
| CN111700991A (en) * | 2020-08-04 | 2020-09-25 | 金陵科技学院 | Compound traditional Chinese medicine feed additive and preparation method and application thereof |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1895291A (en) * | 2006-06-09 | 2007-01-17 | 陈永丽 | Nano-Chinese medicinal biological product and its preparation |
| CN104474438A (en) * | 2014-11-26 | 2015-04-01 | 郑州后羿制药有限公司 | Traditional Chinese medicine composition for promoting pig growth and improving pork quality |
| CN105055838A (en) * | 2015-08-13 | 2015-11-18 | 四川华蜀动物药业有限公司 | Traditional Chinese medicine compound powder for sows and piglets and preparation technology for Chinese herbal compound powder |
| CN105746898A (en) * | 2016-03-09 | 2016-07-13 | 广州格雷特生物科技有限公司 | Chinese herbal medicine feed additive with Folium Callicarpae Nudiflorae and preparation method and application thereof |
| CN106075250A (en) * | 2016-08-17 | 2016-11-09 | 通化万通药业股份有限公司 | Spleen-invigorating granula and preparation method |
-
2016
- 2016-08-30 CN CN201610771916.6A patent/CN106177878B/en active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1895291A (en) * | 2006-06-09 | 2007-01-17 | 陈永丽 | Nano-Chinese medicinal biological product and its preparation |
| CN104474438A (en) * | 2014-11-26 | 2015-04-01 | 郑州后羿制药有限公司 | Traditional Chinese medicine composition for promoting pig growth and improving pork quality |
| CN105055838A (en) * | 2015-08-13 | 2015-11-18 | 四川华蜀动物药业有限公司 | Traditional Chinese medicine compound powder for sows and piglets and preparation technology for Chinese herbal compound powder |
| CN105746898A (en) * | 2016-03-09 | 2016-07-13 | 广州格雷特生物科技有限公司 | Chinese herbal medicine feed additive with Folium Callicarpae Nudiflorae and preparation method and application thereof |
| CN106075250A (en) * | 2016-08-17 | 2016-11-09 | 通化万通药业股份有限公司 | Spleen-invigorating granula and preparation method |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107242370A (en) * | 2017-06-17 | 2017-10-13 | 申学林 | Sucking pig specific enzyme solution mixed feed |
| CN107596204A (en) * | 2017-10-11 | 2018-01-19 | 安徽省宿州市民辉养殖有限公司 | A kind of medicine for pig health care fattening |
| CN107715034A (en) * | 2017-10-25 | 2018-02-23 | 广西沙田仙人滩农业投资有限公司 | A kind of hawthorn medicine for treating a variety of poultry diseases |
| CN111700991A (en) * | 2020-08-04 | 2020-09-25 | 金陵科技学院 | Compound traditional Chinese medicine feed additive and preparation method and application thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN106177878B (en) | 2019-09-20 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN1951481A (en) | Medicament for treating cerebral thrombosis | |
| CN107303384A (en) | It is a kind of to have medicable Chinese medicine composition and its derivative and product to a variety of symptoms | |
| CN1485083A (en) | Capsule for thyroid cancer / tumor and lymph node | |
| CN103721045B (en) | For improving the Chinese traditional immunopoteniators of broiler immunologic function in growth course | |
| CN104042957A (en) | Traditional Chinese medicine (TCM) composition for treating prostatitis | |
| CN106177878A (en) | A kind of pharmaceutical composition promoting growing-finishing pigs and raising immune performance and preparation method thereof | |
| CN112891399A (en) | Traditional Chinese medicine composition and application and preparation method thereof | |
| CN110960619A (en) | Traditional Chinese medicine composition for treating African swine fever | |
| CN102961636B (en) | Pure traditional Chinese medicine composition for treating poultry infectious bursal disease and preparation method thereof | |
| CN103599496B (en) | Traditional Chinese medicine for treatment of chronic gastritis | |
| CN103071120A (en) | Medicine for treating silicosis | |
| CN101874854A (en) | Traditional Chinese medicine composition for tonifying middle-Jiao and Qi and protecting liver for pets and preparation method thereof | |
| CN104940404A (en) | Preparation for preventing pullorum disease and preparation method | |
| CN106266410A (en) | The nutritious Chinese of one boar different phase | |
| CN103611100A (en) | Traditional Chinese medicine for treating toothaches | |
| CN103877544B (en) | Chinese medicine composition for the treatment of broiler ascites syndrome and preparation method thereof | |
| CN107998280A (en) | A kind of poultry Substitutes For Antibiotic and preparation method and application | |
| CN110760422A (en) | Medicinal liquor for tonifying kidney | |
| CN106309879A (en) | Drug combination capable of resisting animal stress and preparation method thereof | |
| CN112957420A (en) | Traditional Chinese medicine health-care preparation and feed for pigs as well as preparation method and application of traditional Chinese medicine health-care preparation and feed | |
| CN111544506A (en) | Deer fetus ointment and preparation method thereof | |
| CN105194046A (en) | Traditional Chinese medicine slimming external application formula and preparation method thereof | |
| CN104771585A (en) | Traditional Chinese medicine composition for treating acute nephritis and preparation method thereof | |
| CN104435319A (en) | Traditional Chinese veterinary medicine for preventing piglet stress reaction | |
| CN105981921A (en) | Chinese herbal medicinal compound premix for laying hens and manufacturing method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |