[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

CN104435319A - Traditional Chinese veterinary medicine for preventing piglet stress reaction - Google Patents

Traditional Chinese veterinary medicine for preventing piglet stress reaction Download PDF

Info

Publication number
CN104435319A
CN104435319A CN201410744407.5A CN201410744407A CN104435319A CN 104435319 A CN104435319 A CN 104435319A CN 201410744407 A CN201410744407 A CN 201410744407A CN 104435319 A CN104435319 A CN 104435319A
Authority
CN
China
Prior art keywords
parts
radix
herbal medicine
stress
traditional chinese
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN201410744407.5A
Other languages
Chinese (zh)
Other versions
CN104435319B (en
Inventor
刘应鹏
范超杰
朱丽平
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zhengzhou Houyi Pharmaceutical Co Ltd
Original Assignee
Zhengzhou Houyi Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zhengzhou Houyi Pharmaceutical Co Ltd filed Critical Zhengzhou Houyi Pharmaceutical Co Ltd
Priority to CN201410744407.5A priority Critical patent/CN104435319B/en
Publication of CN104435319A publication Critical patent/CN104435319A/en
Application granted granted Critical
Publication of CN104435319B publication Critical patent/CN104435319B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539Scutellaria (skullcap)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/06Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/19Acanthaceae (Acanthus family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/19Acanthaceae (Acanthus family)
    • A61K36/195Strobilanthes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/282Artemisia, e.g. wormwood or sagebrush
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/288Taraxacum (dandelion)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/31Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • A61K36/315Isatis, e.g. Dyer's woad
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/35Caprifoliaceae (Honeysuckle family)
    • A61K36/355Lonicera (honeysuckle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/51Gentianaceae (Gentian family)
    • A61K36/515Gentiana
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/65Paeoniaceae (Peony family), e.g. Chinese peony
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704Polygonum, e.g. knotweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/718Coptis (goldthread)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/74Rubiaceae (Madder family)
    • A61K36/744Gardenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • A61K36/804Rehmannia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/85Verbenaceae (Verbena family)
    • A61K36/855Clerodendrum, e.g. glorybower
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1658Proteins, e.g. albumin, gelatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Inorganic Chemistry (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a traditional Chinese veterinary medicine for preventing a piglet stress reaction. The traditional Chinese veterinary medicine is prepared from the following raw materials in parts by weight: 100-200 parts of scutellaria baicalensis, 100-200 parts of cape jasmine, 80-150 parts of liquorice, 100-180 parts of the root bark of the peony tree, 80-150 parts of red paeony root, 90-150 parts of cortex albiziae, 80-120 parts of radix rehmanniae recen, 50-150 parts of felwort, 80-150 parts of coptis chinensis, 100-150 parts of dandelion, 100-200 parts of honeysuckle, 60-80 parts of gypsum, 80-120 parts of folium isatidis, 80-100 parts of sweet wormwood and 50-100 parts of common andrographis herb. According to the traditional Chinese veterinary medicine for preventing the piglet stress reaction prepared by the invention, the formula is scientific and reasonable, and the preparation method is simple and feasible. The test proves that the traditional Chinese veterinary medicine disclosed by the invention can reduce even eliminate the stress reaction, and losses caused by the stress reaction are avoided to a certain degree.

Description

A kind of prevent piglet stress herbal medicine
Technical field
The present invention relates to a kind of veterinary drug, particularly a kind ofly prevent herbal medicine of piglet stress and preparation method thereof.
Background technology
Stress, when referring to that body is subject to suddenly intense destructive stimulation (as wound, operation, hunger etc.), causes a series of general reaction to resist the reaction of destructive stimulus.In livestock breeding industry of today, the stress of piglet is also more common.After pig is subject to the effect of stressor, such as long-distance transport, early weaning piglet, vaccine immunity, piglet are castrated, catch, drive, high temperature, cold, crowded, sting after bucket, injection, operation etc. stimulate, hypothalamus is excited, secretion Corticotrophin-releasing hormone, antepituitary is entered by hypophyseal portal system, make antepituitary secrete adrenocortical hormone (ACTH) to increase, ACTH arrives adrenal gland by blood circulation, impels the release of glucocorticoid.The adrenal gland that stress secrete at the initial stage, also ACTH can be discharged by Stimulation of Pituitary Gland frontal lobe, increasing of ACTH secretion, hinders the absorption of some nutrient substance, strengthens catabolism, inflammation-inhibiting and immunoreation, cause Abwehrkraft des Koepers to decline, the intensity of stressor is large, during persistent, adrenocortical secretion nonfunction can be caused, cause pig to fall ill time serious even dead.
For this situation that pig stress be reflected, except in feeding and management, the position of pig and swinery construction rationally, should avoid the interference that extraneous factor is too much, avoid the crowded group mixed with attention of swinery.Simultaneously carrying out transporting for long-distance, early weaning piglet, vaccine immunity, piglet castrate, catch, drive, inject, operation etc. stimulate before the effective use loss that prevents the herbal medicine of piglet stress also can to a certain degree avoid stress to cause.
Summary of the invention
The object of the present invention is to provide a kind of herbal medicine preventing piglet stress, have and prevent environmental stimuli to the feature of the stress that piglet is caused efficiently.Meanwhile, the present invention also provides a kind of preparation method of preventing the herbal medicine of piglet stress.
In order to realize above object, the technical solution adopted in the present invention is:
Prevent a herbal medicine for piglet stress, be made up of the raw material of following weight portion: Radix Scutellariae 100 parts ~ 200 parts, Fructus Gardeniae 100 parts ~ 200 parts, Radix Glycyrrhizae 80 parts ~ 150, Cortex Moutan 100 parts ~ 180 parts, Radix Paeoniae Rubra 80 parts ~ 150 parts, Cortex Albiziae 90 parts ~ 150 parts, Radix Rehmanniae 80 parts ~ 120 parts, Radix Gentianae 50 parts ~ 150 parts, Rhizoma Coptidis 80 parts ~ 150 parts, Herba Taraxaci 100 parts ~ 150 parts, Flos Lonicerae 100 parts ~ 200 parts, 60 parts ~ 80 parts, Gypsum Fibrosum, Folium Isatidis 80 parts ~ 120 parts, Herba Artemisiae Annuae 80 parts ~ 100 parts, Herba Andrographis 50 parts ~ 100 parts.
Further, prevent a herbal medicine for piglet stress, be made up of the raw material of following weight portion: Radix Scutellariae 150 parts ~ 200 parts, Fructus Gardeniae 150 parts ~ 200 parts, Radix Glycyrrhizae 100 parts ~ 150, Cortex Moutan 100 parts ~ 180 parts, Radix Paeoniae Rubra 80 parts ~ 150 parts, Cortex Albiziae 100 parts ~ 150 parts, Radix Rehmanniae 80 parts ~ 120 parts, Radix Gentianae 50 parts ~ 150 parts, Rhizoma Coptidis 80 parts ~ 150 parts, Herba Taraxaci 100 parts ~ 150 parts, Flos Lonicerae 100 parts ~ 200 parts, 60 parts ~ 80 parts, Gypsum Fibrosum, Folium Isatidis 80 parts ~ 120 parts, Herba Artemisiae Annuae 80 parts ~ 100 parts, Herba Andrographis 50 parts ~ 100 parts.
The preparation method of the herbal medicine of above-mentioned prevention piglet stress, comprise the following steps: take above-mentioned raw materials, decoct with water 1-3 time, each 0.5-2h, merging filtrate, filters, it is 1.28-1.40 thick paste that filtrate is concentrated into density, add tannalbin, white sugar, dextrin, make granule, be drying to obtain.
The described multiple that adds water is 8-12 times of raw material.
Describedly add tannalbin 1 part, white sugar 1 part, 1.6 parts, dextrin.
Radix Scutellariae: sweet in the mouth, slightly warm in nature, gas is thin and taste is dense, can rise and can fall, and the yang aspect of yang is also, nontoxic.Special QI invigorating.To start with warp that is lunar, the few the moon of lunar, the hands of foot.Its function is a lot of, and its only effect person, especially enriching blood.Invigorating the spleen and replenishing QI, tonifying the lung consolidating superficial resistance, inducing diuresis to remove edema.Weak for the deficiency of vital energy, be few loose stool, sinking of QI of middle-JIAO, exterior deficiency spontaneous perspiration, deficiency of vital energy edema Radix Astragali disk, interior-deficiency dull yellowish colored skin, interior-heat is quenched one's thirst, also can enhancing human body immunity function, protect the liver, diuresis, defying age, anti-stress and antibacterial action widely.
Radix Glycyrrhizae: Radix Glycyrrhizae property is put down, and sweet in the mouth, returns 12 warps.There is removing toxic substances, eliminate the phlegm, pain relieving, spasmolytic is so that the pharmacological action such as anticancer.In the traditional Chinese medical science, Radix Glycyrrhizae invigorating the spleen and replenishing QI, grows and coughs lung moistening, and emergency is detoxified, and is in harmonious proportion hundred medicines.Include glycyrrhizin, can antiallergic, antiinflammatory, lessly stress wait effect.Clinical practice divides, and " life is used " is not with " processed with honey ".Raw with curing mainly laryngopharynx swelling and pain, cellulitis skin infection, gastrointestinal ulceration and solution poison of drug, alimentary toxicosis etc.; Processed with honey cures mainly spleen and stomach function and goes down, and large loose stool is thin, weak heating and cough, cardiopalmus etc.
Folium Isatidis: have another name called Folium Isatidis, has heat-clearing and toxic substances removing, cooling blood for hemostasis, effect of speckle removing.Cure mainly fever caused by exogenous pathogenic factors, maculae caused by violent heat pathogen, intenseness of heat excessive thirst.This medicine extensive use clinically in recent years, control except above-mentioned all diseases except available, can be used for again expectorant heat stagnation lung, cough up phlegm yellow thick; Especially be usually used in popular second encephalitis, both can be applied to prevention by single, and Radix Bupleuri, Flos Lonicerae, Fructus Forsythiae, Radix Isatidis, Radix Scrophulariae, the Radix Rehmanniae etc. can be coordinated again, can removing summer-heat edema caused by disorder of QI, battalion point pyretic toxicity, availablely control various encephalitis b, and comparatively suitable with partial heat type.
Flos Lonicerae: Flos Lonicerae, has another name called Radix Ophiopogonis, Flos Lonicerae, Flos Lonicerae etc., is described as the good medicine of heat-clearing and toxic substances removing from ancient times.Its property sweet cold fragrance, clearing away heat with drugs sweet in flavor and cold in nature and not injuring one's stomach, fragrance thoroughly reaches and can be eliminating evil.Flos Lonicerae can dispelling wind-heat, also kind removing summer-heat blood poison, for various febrile disease, as fever of the body, heating, sends out all Be very effective such as speckle, pyretic toxicity carbuncle sore, laryngopharynx swelling and pain.With the Radix Astragali, Radix Glycyrrhizae etc. with the use of the effect that can reach anti-bacteria and anti-virus, antipyretic, enhancing human body immunity function.
The present invention adopts the Chinese crude drugs such as Radix Scutellariae, Fructus Gardeniae, Radix Glycyrrhizae, Cortex Moutan, Radix Paeoniae Rubra, Cortex Albiziae, Radix Rehmanniae, Radix Gentianae, Rhizoma Coptidis, Herba Taraxaci, Flos Lonicerae, Gypsum Fibrosum, Folium Isatidis, Herba Artemisiae Annuae, Herba Andrographis to be combined into a kind of herbal medicine preventing piglet stress.This prescription, according to the principle of monarch, accomplishes again the effect of etiological treatment while reaching symptomatic treatment, the pure Chinese medicine of the party, has no side effect.Wherein Radix Scutellariae, Fructus Gardeniae, Radix Glycyrrhizae, Cortex Moutan is monarch drug, antiallergic, antiinflammatory, less stress; Herba Taraxaci, Flos Lonicerae, Herba Artemisiae Annuae, Herba Andrographis are ministerial drug, can anti-inflammation, antipyretic, enhancing human body immunity function effect; Radix Paeoniae Rubra, Cortex Albiziae, Radix Rehmanniae, Radix Gentianae, Rhizoma Coptidis for making medicine, can and middle emergency coordinating the actions of various ingredients in a prescription; All medicines share, and play altogether, antiallergic, antiinflammatory, less stress, effect of immunity moderation.
The herbal medicine of prevention piglet stress prepared by the present invention, scientific formulation is reasonable, and preparation method is simple, proves that herbal medicine of the present invention can reduce the generation of even stopping stress, in the loss avoiding stress to cause to a certain degree by test.
Detailed description of the invention
embodiment 1
Prevent a herbal medicine for piglet stress, be made up of the raw material of following weight portion: Radix Scutellariae 100 parts ~ 200 parts, Fructus Gardeniae 100 parts ~ 200 parts, Radix Glycyrrhizae 80 parts ~ 150, Cortex Moutan 100 parts ~ 180 parts, Radix Paeoniae Rubra 80 parts ~ 150 parts, Cortex Albiziae 90 parts ~ 150 parts, Radix Rehmanniae 80 parts ~ 120 parts, Radix Gentianae 50 parts ~ 150 parts, Rhizoma Coptidis 80 parts ~ 150 parts, Herba Taraxaci 100 parts ~ 150 parts, Flos Lonicerae 100 parts ~ 200 parts, 60 parts ~ 80 parts, Gypsum Fibrosum, Folium Isatidis 80 parts ~ 120 parts, Herba Artemisiae Annuae 80 parts ~ 100 parts, Herba Andrographis 50 parts ~ 100 parts.
The preparation method of the herbal medicine of above-mentioned prevention piglet stress, comprise the following steps: take above-mentioned raw materials, decoct with water 1-3 time, each 0.5-2h, merging filtrate, filters, it is 1.28-1.40 thick paste that filtrate is concentrated into density, add tannalbin, white sugar, dextrin, make granule, be drying to obtain.
The described multiple that adds water is 8-12 times of raw material.
Describedly add tannalbin 1 part, white sugar 1 part, 1.6 parts, dextrin.
embodiment 2
Prevent a herbal medicine for piglet stress, be made up of the raw material of following weight portion: Radix Scutellariae 150 parts ~ 200 parts, Fructus Gardeniae 150 parts ~ 200 parts, Radix Glycyrrhizae 100 parts ~ 150, Cortex Moutan 100 parts ~ 180 parts, Radix Paeoniae Rubra 80 parts ~ 150 parts, Cortex Albiziae 100 parts ~ 150 parts, Radix Rehmanniae 80 parts ~ 120 parts, Radix Gentianae 50 parts ~ 150 parts, Rhizoma Coptidis 80 parts ~ 150 parts, Herba Taraxaci 100 parts ~ 150 parts, Flos Lonicerae 100 parts ~ 200 parts, 60 parts ~ 80 parts, Gypsum Fibrosum, Folium Isatidis 80 parts ~ 120 parts, Herba Artemisiae Annuae 80 parts ~ 100 parts, Herba Andrographis 50 parts ~ 100 parts.
The preparation method of the herbal medicine of above-mentioned prevention piglet stress, comprises the following steps: take above-mentioned raw materials, decocts with water 3 times, each 1h, merging filtrate, filter, filtrate is concentrated into thick paste, and density is 1.28, add tannalbin, white sugar, dextrin, make granule, be drying to obtain.
The described multiple that adds water is 12 times of raw material.
Describedly add tannalbin 1 part, white sugar 1 part, 1.6 parts, dextrin.
embodiment 3
Prevent a herbal medicine for piglet stress, be made up of the raw material of following weight portion: Radix Scutellariae 100 parts, Fructus Gardeniae 170 parts, 130 parts, Radix Glycyrrhizae, Cortex Moutan 125 parts, Radix Paeoniae Rubra 105 parts, Cortex Albiziae 91 parts, Radix Rehmanniae 98 parts, Radix Gentianae 150 parts, Rhizoma Coptidis 81 parts, Herba Taraxaci 125 parts, Flos Lonicerae 140 parts, 68 parts, Gypsum Fibrosum, Folium Isatidis 120 parts, Herba Artemisiae Annuae 95 parts, Herba Andrographis 98 parts.
Preparation method is: take various raw material, adds 12 times of soak by water 3 times, 2 hours first times, second time 1 hour, for the third time 30min merging filtrate, and filter, filtrate is concentrated into thick paste, and density is 1.4, adds tannalbin, white sugar, dextrin, makes granule, be drying to obtain.
Usage and dosage: this product 50g, is watered 300-400g or spice 200-300g, is used in conjunction 3-4 days.This product is applicable to piglet and arrives reduction by (immunity, early weaning, operation etc.) use before artificial environmental stimuli or eliminating stress.
embodiment 4
Prevent a herbal medicine for piglet stress, be made up of the raw material of following weight portion: Radix Scutellariae 150 parts, Fructus Gardeniae 150 parts, 100 parts, Radix Glycyrrhizae, Cortex Moutan 150 parts, Radix Paeoniae Rubra 100 parts, Cortex Albiziae 120 parts, Radix Rehmanniae 100 parts, Radix Gentianae 100 parts, Rhizoma Coptidis 100 parts, Herba Taraxaci 120 parts, Flos Lonicerae 150 parts, 70 parts, Gypsum Fibrosum, Folium Isatidis 100 parts, Herba Artemisiae Annuae 90 parts, Herba Andrographis 80 parts.
Preparation method is: take various raw material, adds 10 times of soak by water 2 times, 2 hours first times, second time 1.5 hours, merging filtrate, and filter, filtrate is concentrated into thick paste, and density is 1.28, adds tannalbin, white sugar, dextrin, makes granule, be drying to obtain.
Usage and dosage: this product 50g, is watered 300-400g or spice 200-300g, is used in conjunction 3-4 days.This product is applicable to piglet and arrives reduction by (immunity, early weaning, operation etc.) use before artificial environmental stimuli or eliminating stress.
embodiment 5
Prevent a herbal medicine for piglet stress, be made up of the raw material of following weight portion: Radix Scutellariae 99 parts, Fructus Gardeniae 180 parts, Radix Glycyrrhizae 125, Cortex Moutan 110 parts, Radix Paeoniae Rubra 80 parts, Cortex Albiziae 130 parts, Radix Rehmanniae 105 parts, Radix Gentianae 95 parts, Rhizoma Coptidis 146 parts, Herba Taraxaci 148 parts, Flos Lonicerae 110 parts, 66 parts, Gypsum Fibrosum, Folium Isatidis 85 parts, Herba Artemisiae Annuae 84 parts, Herba Andrographis 92 parts.
Preparation method is: take various raw material, decocts with water 1 time, decocts 2h, and filter, filtrate is concentrated into thick paste, and density is 1.3 add tannalbin, white sugar, dextrin, makes granule, is drying to obtain.Usage and dosage: this product 50g, is watered 300-400g or spice 200-300g, is used in conjunction 3-4 days.
Attention: this product is applicable to piglet and arrives reduction by (immunity, early weaning, operation etc.) use before artificial environmental stimuli or eliminating stress.
In herbal medicine embodiment 6-16 of the present invention, each raw material weight number is in table 1, and in embodiment 17-26, each raw material weight number is in table 2, the other the same as in Example 3.
each raw material weight number table in table 1 herbal medicine of the present invention embodiment 5-15
each raw material weight number table in table 2 herbal medicine of the present invention embodiment 17-26
test example
Use the effect of concrete description of test herbal medicine of the present invention below:
Laboratory animal: according to the principle that immune programme for children, age in days, body condition are relatively consistent, adopts the method for grouping in nest, piglet is divided into 4 groups at random, often organizes 20.
The sodium selenite of the first five day of vaccine immunity is chosen in this experiment, about 25 ages in days, and body weight 7 kilograms (± 500g).
Experiment material: the herbal medicine of preparation in above-described embodiment 3, embodiment 4, embodiment 5.
Experimental procedure: be divided into four groups by above-mentioned at random for examination piglet, be respectively embodiment 3 groups, embodiment 4 groups, embodiment 5 groups, blank group.Get medicine 50g in above-described embodiment respectively, add water 300g, does drinking water administration, is used in conjunction 3d, and wherein matched group is only for drinking-water.
Specific experiment result is as follows:
Embodiment 3 groups: occur after immunity inoculation that the piglet of stress has 4, the astasia that cardinal symptom shows as lassitude, feed intake declines, indivedual appearance is slighter.
Embodiment 4 groups: do not have piglet to occur stress after immunity inoculation, in order, feed intake is normal for this experimental group piglet growth.
Embodiment 5 groups: occur after immunity inoculation that the piglet of stress has 2, the astasia that cardinal symptom shows as lassitude, feed intake declines, indivedual appearance is slighter.
Blank group: systemic immune response appears in piglets more than half after immunity inoculation, shows as mental status not good, and feed intake declines, individually with the symptom such as astasia, skin rubefaction.
Stress is castrated primarily of long-distance transport, early weaning piglet, vaccine immunity, piglet, catch, drive, high temperature, cold, crowded, sting and cause after bucket, injection, operation etc. stimulate, not only have impact on the health of healthy domestic animal, also cause harm to economy.Above-mentioned experimental result shows, compared to matched group, after after vaccine immunity, piglet uses herbal medicine provided by the invention, stress greatly reduces the situation even occurring not having stress, show that herbal medicine of the present invention can reduce the generation of even stopping stress, in the loss avoiding stress to cause to a certain degree.

Claims (5)

1. prevent a herbal medicine for piglet stress, it is characterized in that: be made up of the raw material of following weight portion: Radix Scutellariae 100 parts ~ 200 parts, Fructus Gardeniae 100 parts ~ 200 parts, Radix Glycyrrhizae 80 parts ~ 150, Cortex Moutan 100 parts ~ 180 parts, Radix Paeoniae Rubra 80 parts ~ 150 parts, Cortex Albiziae 90 parts ~ 150 parts, Radix Rehmanniae 80 parts ~ 120 parts, Radix Gentianae 50 parts ~ 150 parts, Rhizoma Coptidis 80 parts ~ 150 parts, Herba Taraxaci 100 parts ~ 150 parts, Flos Lonicerae 100 parts ~ 200 parts, 60 parts ~ 80 parts, Gypsum Fibrosum, Folium Isatidis 80 parts ~ 120 parts, Herba Artemisiae Annuae 80 parts ~ 100 parts, Herba Andrographis 50 parts ~ 100 parts.
2. the herbal medicine of prevention piglet stress as claimed in claim 1, is characterized in that: be made up of the raw material of following weight portion: Radix Scutellariae 150 parts ~ 200 parts, Fructus Gardeniae 150 parts ~ 200 parts, Radix Glycyrrhizae 100 parts ~ 150, Cortex Moutan 100 parts ~ 180 parts, Radix Paeoniae Rubra 80 parts ~ 150 parts, Cortex Albiziae 100 parts ~ 150 parts, Radix Rehmanniae 80 parts ~ 120 parts, Radix Gentianae 50 parts ~ 150 parts, Rhizoma Coptidis 80 parts ~ 150 parts, Herba Taraxaci 100 parts ~ 150 parts, Flos Lonicerae 100 parts ~ 200 parts, 60 parts ~ 80 parts, Gypsum Fibrosum, Folium Isatidis 80 parts ~ 120 parts, Herba Artemisiae Annuae 80 parts ~ 100 parts, Herba Andrographis 50 parts ~ 100 parts.
3. the preparation method of the herbal medicine of prevention piglet stress as claimed in claim 1 or 2, it is characterized in that comprising the following steps: get above-mentioned raw materials, decoct with water 1-3 time, each 0.5-2h, merging filtrate, filters, it is 1.28-1.40 thick paste that filtrate is concentrated into density, add tannalbin, white sugar, dextrin, make granule, be drying to obtain.
4. the preparation method of the herbal medicine of prevention piglet stress as claimed in claim 3, is characterized in that: the multiple that adds water is 8-12 times of raw material.
5. the preparation method of the herbal medicine of prevention piglet stress as claimed in claim 3, is characterized in that: add tannalbin 1 part, white sugar 1 part, 1.6 parts, dextrin.
CN201410744407.5A 2014-12-09 2014-12-09 A kind of herbal medicine for preventing piglet stress reaction Active CN104435319B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201410744407.5A CN104435319B (en) 2014-12-09 2014-12-09 A kind of herbal medicine for preventing piglet stress reaction

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201410744407.5A CN104435319B (en) 2014-12-09 2014-12-09 A kind of herbal medicine for preventing piglet stress reaction

Publications (2)

Publication Number Publication Date
CN104435319A true CN104435319A (en) 2015-03-25
CN104435319B CN104435319B (en) 2017-11-14

Family

ID=52882580

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201410744407.5A Active CN104435319B (en) 2014-12-09 2014-12-09 A kind of herbal medicine for preventing piglet stress reaction

Country Status (1)

Country Link
CN (1) CN104435319B (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105124167A (en) * 2015-09-28 2015-12-09 金陵科技学院 Anti-stress traditional Chinese medicine feed additive as well as preparation method and application thereof
CN106177559A (en) * 2016-08-22 2016-12-07 牛金鹏 A kind of herbal medicine preventing and treating chicken heat shock reaction

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003013495A1 (en) * 2001-08-08 2003-02-20 Smothers Don L Formulation and method for reduction of stress in meat-producing animals
CN102283931A (en) * 2011-09-02 2011-12-21 河南省农业科学院 Traditional Chinese medicine composition for preventing and curing diarrhea of suckling pigs

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003013495A1 (en) * 2001-08-08 2003-02-20 Smothers Don L Formulation and method for reduction of stress in meat-producing animals
CN102283931A (en) * 2011-09-02 2011-12-21 河南省农业科学院 Traditional Chinese medicine composition for preventing and curing diarrhea of suckling pigs

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
苏尼花等: "应激与中药防治", 《内蒙古畜牧科学》 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105124167A (en) * 2015-09-28 2015-12-09 金陵科技学院 Anti-stress traditional Chinese medicine feed additive as well as preparation method and application thereof
CN105124167B (en) * 2015-09-28 2018-07-06 金陵科技学院 A kind of resisting stress Chinese herbal feed additive and preparation method and application
CN106177559A (en) * 2016-08-22 2016-12-07 牛金鹏 A kind of herbal medicine preventing and treating chicken heat shock reaction

Also Published As

Publication number Publication date
CN104435319B (en) 2017-11-14

Similar Documents

Publication Publication Date Title
CN103705897B (en) A kind of cancer relieves the pain plaster
CN103251873B (en) Traditional Chinese veterinary medicine capable of helping to digest and remove retention
CN102078419B (en) Medicament for preventing and treating porcine reproductive and respiratory syndrome (PRRS) and preparation method thereof
CN102450517A (en) Broiler feed and traditional Chinese medicine additive used by same
CN104069294A (en) Anti-cancer Chinese patent medicine preparation and extraction and compatibility process thereof
CN105410346A (en) Cultured penaeus vannamei survival rate improving traditional Chinese medicine preparation and preparation method thereof
CN103638372A (en) Traditional Chinese medicine composition, preparation method and application thereof
CN102641366A (en) Traditional Chinese medicine composition for preventing and treating proventriculitis and gizzard erosion of poultry
CN105233116A (en) Traditional Chinese medicine composition for preventing and controlling respiratory tract infection of chicken and preparation method thereof
CN103656122B (en) Chinese medicine for the treatment of fever caused by exogenous pathogenic factors and preparation method thereof
CN101637519A (en) Traditional Chinese veterinary medicine for reinforcing detoxifying function of liver and kidney of livestock and poultry
CN103494996A (en) Pharmaceutical composition for improving immunity of livestock and poultry and preparation method of pharmaceutical composition
CN104435319A (en) Traditional Chinese veterinary medicine for preventing piglet stress reaction
CN103054995A (en) Pure Chinese medicinal composition for treating honeybee pupa disease and preparation method thereof
CN104940404A (en) Preparation for preventing pullorum disease and preparation method
CN106309879A (en) Drug combination capable of resisting animal stress and preparation method thereof
CN105168496B (en) A kind of Chinese traditional medicine composition and preparation method preventing and treating Duck Hepatitis Virus
CN104688882A (en) TCM (Traditional Chinese Medicine) composition for treating fever in children
CN105381044A (en) Traditional Chinese medicine composition for preventing and controlling muscular stomach erosion symptoms of poultry
CN100333749C (en) Chinese medicine for preventing and controlling infants repeated respiratory tract inflammation and producing method
CN103211989A (en) Chinese medicine composition for preventing and treating bird flu and preparation method of Chinese medicine composition
CN102552495A (en) Traditional Chinese medicine composition for preventing poultry syndrome of pathogen invading lung-defense phase
CN102228568B (en) Chinese medicine for treating warm heat diseases in livestock and poultry and preparation method thereof
CN102727821B (en) Oral liquid for treating fever
CN108379437A (en) A kind of feed addictive and preparation method thereof of prevention brickpox

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
CB02 Change of applicant information
CB02 Change of applicant information

Address after: 451164 eastern side of Donggang Avenue, Zhengzhou airport economic comprehensive test area, Henan

Applicant after: Henan Hou Yi Industry Group Co., Ltd.

Address before: 451100 Xingang, Henan, Xinzheng Port Road East Side

Applicant before: Zhengzhou Houyi Pharmaceutical Co., Ltd.

GR01 Patent grant
GR01 Patent grant