BE905110A - Poly-4-aminopyrrole-2-carboxamides et derives, procede pour leur preparation et leurs utilisations therapeutiques. - Google Patents

Poly-4-aminopyrrole-2-carboxamides et derives, procede pour leur preparation et leurs utilisations therapeutiques.

Info

Publication number: BE905110A
Authority: BE; Belgium
Prior art keywords: group; aminopyrrole; carboxamides; poly; derivatives
Prior art date: 1985-07-16

Application number

BE0/216924A

Other languages

English (en)

French (fr)

Inventor

Arcamone Federico

Mongelli Nicola

Penco Sergio

Original Assignee

Erba Farmitalia

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-07-16

Filing date

1986-07-15

Publication date

1987-01-15

1985-07-16 Priority claimed from GB858517922A external-priority patent/GB8517922D0/en

1986-06-04 Priority claimed from GB868613594A external-priority patent/GB8613594D0/en

1986-07-15 Application filed by Erba Farmitalia filed Critical Erba Farmitalia

1987-01-15 Publication of BE905110A publication Critical patent/BE905110A/fr

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Communicable Diseases (AREA)
Molecular Biology (AREA)
Oncology (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
Genetics & Genomics (AREA)
Virology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Pyrrole Compounds (AREA)
Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
Polyamides (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)

BE0/216924A 1985-07-16 1986-07-15 Poly-4-aminopyrrole-2-carboxamides et derives, procede pour leur preparation et leurs utilisations therapeutiques. BE905110A (fr)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB858517922A GB8517922D0 (en)	1985-07-16	1985-07-16	Carboxamido derivatives
GB868613594A GB8613594D0 (en)	1986-06-04	1986-06-04	Poly-4-aminopyrrole-2-carboxamido derivatives

Publications (1)

Publication Number	Publication Date
BE905110A true BE905110A (fr)	1987-01-15

Family

ID=26289538

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BE0/216924A BE905110A (fr)	1985-07-16	1986-07-15	Poly-4-aminopyrrole-2-carboxamides et derives, procede pour leur preparation et leurs utilisations therapeutiques.

Country Status (26)

Country	Link
JP (1)	JPH0780843B2 (nl)
KR (1)	KR930010496B1 (nl)
CN (1)	CN1018825B (nl)
AT (1)	AT387013B (nl)
AU (1)	AU587841B2 (nl)
BE (1)	BE905110A (nl)
CA (1)	CA1285934C (nl)
CH (1)	CH674206A5 (nl)
CS (1)	CS276981B6 (nl)
DE (1)	DE3623880A1 (nl)
DK (1)	DK335986A (nl)
ES (1)	ES2000502A6 (nl)
FI (1)	FI83640C (nl)
FR (1)	FR2585018B1 (nl)
GB (1)	GB2178036B (nl)
GR (1)	GR861841B (nl)
HU (1)	HU205949B (nl)
IE (1)	IE59073B1 (nl)
IL (1)	IL79402A (nl)
IT (1)	IT1196488B (nl)
NL (1)	NL8601837A (nl)
NO (1)	NO168826C (nl)
NZ (1)	NZ216829A (nl)
PH (1)	PH24714A (nl)
PT (1)	PT82984B (nl)
SE (1)	SE468642B (nl)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN85103908A (zh) *	1985-07-16	1986-11-05	法米塔利·卡洛·埃尔巴有限公司	制备4′-表多克索红菌素的新方法
GB8906709D0 (en) *	1989-03-23	1989-05-10	Creighton Andrew M	Acryloyl substituted pyrrole derivatives
IT1243389B (it) *	1990-11-22	1994-06-10	Menarini Farma Ind	Derivati poliaminopirrolcarbossiamidici, processi di preparazione e composizioni farmaceutiche che li contengono.
AU1224392A (en) *	1991-02-06	1992-09-07	Synphar Laboratories, Inc.	Oligopeptide antiretroviral agents
IT1247878B (it) *	1991-02-15	1995-01-05	Menarini Farma Ind	Derivati poli-4-aminopirrol-2-carbossiamidici,processi di preparazione e composizioni farmaceutiche che li contengono
GB2260134A (en) *	1991-10-04	1993-04-07	Erba Carlo Spa	Derivatives of poly-5-amino-3-carboxy-1-methyl compounds
IT1262921B (it) *	1992-01-10	1996-07-22	Federico Arcamone	Agenti antitumorali analoghi di oligopeptidi pirrol-amidinici retroversi processi di preparazione e prodotti farmaceutici che li contengono
GB9416005D0 (en) *	1994-08-08	1994-09-28	Erba Carlo Spa	Peptidic compounds analogous to distamycin a and process for their preparation
ATE206699T1 (de) *	1995-09-12	2001-10-15	Kyowa Hakko Kogyo Kk	Uch-15-verbindungen
WO1997028123A1 (en) *	1996-02-02	1997-08-07	Pharmacia & Upjohn S.P.A.	Distamycin derivatives, process for preparing them, and their use as antitumor and antiviral agents
GB9615692D0 (en) *	1996-07-25	1996-09-04	Pharmacia Spa	Acryloyl substituted distamycin derivatives, process for preparing them, and their use as antitumor and antiviral agents
GB0011059D0 (en)	2000-05-08	2000-06-28	Pharmacia & Upjohn Spa	Use of substituted acryloyl distamycin derivatives in the treatment of tumours associated with high levels of glutathione
GB0015447D0 (en)	2000-06-23	2000-08-16	Pharmacia & Upjohn Spa	Combined therapy against tumors comprising substituted acryloyl derivates and alkylating agents
GB0015446D0 (en)	2000-06-23	2000-08-16	Pharmacia & Upjohn Spa	Combined therapy against tumors comprising substituted acryloyl distamycin derivates,taxanes and/or antimetabolites
GB0016447D0 (en)	2000-07-04	2000-08-23	Pharmacia & Upjohn Spa	Process for preparing distamycin derivatives
US6969592B2 (en)	2001-09-26	2005-11-29	Pharmacia Italia S.P.A.	Method for predicting the sensitivity to chemotherapy

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR86210E (nl)	1963-04-04	1966-03-23
BE666612A (nl) *	1963-07-26	1965-11-03
BR6461040D0 (pt) *	1963-07-26	1973-08-02	Farmaceutici Italia	Processo para preparar novos derivados de pirrol
DE1795539A1 (de) *	1963-07-26	1972-01-13	Farmaceutici Italia	Verfahren zur Herstellung von neuen Pyrrolderivaten und ihren Salzen
NL130086C (nl) *	1964-07-14	1970-06-15
CN85103908A (zh) *	1985-07-16	1986-11-05	法米塔利·卡洛·埃尔巴有限公司	制备4′-表多克索红菌素的新方法

1986
- 1986-07-11 AT AT0188886A patent/AT387013B/de not_active IP Right Cessation
- 1986-07-11 SE SE8603098A patent/SE468642B/sv not_active IP Right Cessation
- 1986-07-14 HU HU862904A patent/HU205949B/hu not_active IP Right Cessation
- 1986-07-14 NL NL8601837A patent/NL8601837A/nl not_active Application Discontinuation
- 1986-07-14 NZ NZ216829A patent/NZ216829A/xx unknown
- 1986-07-14 ES ES8600290A patent/ES2000502A6/es not_active Expired
- 1986-07-14 IE IE187586A patent/IE59073B1/en not_active IP Right Cessation
- 1986-07-14 IL IL79402A patent/IL79402A/xx not_active IP Right Cessation
- 1986-07-14 AU AU60202/86A patent/AU587841B2/en not_active Ceased
- 1986-07-15 IT IT21125/86A patent/IT1196488B/it active
- 1986-07-15 CA CA000513760A patent/CA1285934C/en not_active Expired - Fee Related
- 1986-07-15 JP JP61164879A patent/JPH0780843B2/ja not_active Expired - Lifetime
- 1986-07-15 PH PH34014A patent/PH24714A/en unknown
- 1986-07-15 DK DK335986A patent/DK335986A/da not_active Application Discontinuation
- 1986-07-15 DE DE3623880A patent/DE3623880A1/de not_active Withdrawn
- 1986-07-15 PT PT82984A patent/PT82984B/pt not_active IP Right Cessation
- 1986-07-15 KR KR1019860005715A patent/KR930010496B1/ko not_active IP Right Cessation
- 1986-07-15 GR GR861841A patent/GR861841B/el unknown
- 1986-07-15 NO NO862860A patent/NO168826C/no unknown
- 1986-07-15 CH CH2820/86A patent/CH674206A5/de not_active IP Right Cessation
- 1986-07-15 FR FR868610294A patent/FR2585018B1/fr not_active Expired
- 1986-07-15 BE BE0/216924A patent/BE905110A/fr not_active IP Right Cessation
- 1986-07-16 FI FI862959A patent/FI83640C/fi not_active IP Right Cessation
- 1986-07-16 CN CN86104787A patent/CN1018825B/zh not_active Expired
- 1986-07-16 CS CS865412A patent/CS276981B6/cs unknown
- 1986-07-16 GB GB8617292A patent/GB2178036B/en not_active Expired

Also Published As

Publication number	Publication date
KR870001201A (ko)	1987-03-12
HUT43088A (en)	1987-09-28
DK335986A (da)	1987-01-17
AT387013B (de)	1988-11-25
SE8603098L (sv)	1987-01-17
NZ216829A (en)	1989-03-29
IT8621125A1 (it)	1988-01-15
KR930010496B1 (ko)	1993-10-25
GB2178036A (en)	1987-02-04
CN1018825B (zh)	1992-10-28
GB8617292D0 (en)	1986-08-20
FI862959A0 (fi)	1986-07-16
IE59073B1 (en)	1994-01-12
FR2585018A1 (fr)	1987-01-23
CS8605412A2 (en)	1991-03-12
DE3623880A1 (de)	1987-01-29
JPS6277362A (ja)	1987-04-09
GR861841B (en)	1986-11-18
PH24714A (en)	1990-10-01
CH674206A5 (nl)	1990-05-15
AU6020286A (en)	1987-01-22
IT8621125A0 (it)	1986-07-15
CS276981B6 (en)	1992-11-18
NL8601837A (nl)	1987-02-16
FI862959A (fi)	1987-01-17
SE468642B (sv)	1993-02-22
GB2178036B (en)	1989-08-16
ATA188886A (de)	1988-04-15
JPH0780843B2 (ja)	1995-08-30
SE8603098D0 (sv)	1986-07-11
FR2585018B1 (fr)	1989-07-13
AU587841B2 (en)	1989-08-31
NO862860D0 (no)	1986-07-15
IL79402A0 (en)	1986-10-31
DK335986D0 (da)	1986-07-15
FI83640C (fi)	1991-08-12
IT1196488B (it)	1988-11-16
CA1285934C (en)	1991-07-09
IL79402A (en)	1991-06-10
FI83640B (fi)	1991-04-30
IE861875L (en)	1987-01-16
ES2000502A6 (es)	1988-03-01
NO168826C (no)	1992-04-08
NO862860L (no)	1987-01-19
NO168826B (no)	1991-12-30
PT82984B (pt)	1989-01-30
CN86104787A (zh)	1987-02-18
HU205949B (en)	1992-07-28
PT82984A (en)	1986-08-01

Publication	Publication Date	Title
BE905110A (fr)	1987-01-15	Poly-4-aminopyrrole-2-carboxamides et derives, procede pour leur preparation et leurs utilisations therapeutiques.
TNSN87042A1 (fr)	1990-01-01	Procede de preparation de nouveaux steroides comportant un cycle spirannique en position 17
FR2603588A1 (fr)	1988-03-11	Thiazolo (4,5-c) quinoleines, procede de preparation et medicaments les contenant
BE900345A (fr)	1984-12-03	Composition pharmaceutique ophtalmiques a base d'un derive d'acide phenylacetique.
BE901545A (fr)	1985-07-22	Nouveaux derives de la furo-(3,4-c)-pyridine substitues en position 6, un procede pour leur preparation et compositions therapeutiques a base de ces derives.
BE900842A (fr)	1985-04-18	Nouveaux complexes de platine et leur application en therapeutique.
EP0287353A3 (en)	1990-06-13	Chiral synthesis of anthracyclines from substituted anthraquinones
FR2637286A1 (fr)	1990-04-06	Nouveaux derives benzoxazolinoniques, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent
FR2506772A1 (fr)	1982-12-03	Glycosides d'anthracycline, procede pour les preparer et leur usage comme medicament
FR2452483A1 (fr)	1980-10-24	Derives d'alcenylphenylmaleimides, leurs dimeres lineaires et leur procede de preparation
FR2407941A1 (fr)	1979-06-01	Nouveaux derives de cholesterol
FR2413358A1 (fr)	1979-07-27	Nouveaux derives de 2-aminomethylphenol, utiles notamment comme agents anti-inflammatoires, et leur procede de preparation
FR2506313A1 (fr)	1982-11-26	Derives de l'acide n-acetylneuraminique et leur preparation
FR2447375A1 (fr)	1980-08-22	Analogues de la prostaglandine e1 et compositions pharmaceutiques les contenant
FR2397425A1 (fr)	1979-02-09	Nouveaux derives de la daunorubicine, leur preparation et les compositions qui les contiennent
FR2455596A1 (fr)	1980-11-28	Nouveaux antibiotiques presentant une activite antibacterienne, leur procede de production, leur souche servant a leur obtention et les compositions pharmaceutiques les contenant
FR2445316A1 (fr)	1980-07-25	Nouveaux derives n-substitues de l'acide aziridinyl 2-carboxylique presentant une activite immunostimulante, leur procede de preparation et leurs applications therapeutiques
BE905654A (fr)	1987-04-24	Derives de la armstrong 2-1,2,4-triazoline-5-one, procede pour leur preparation et leurs utilisations.
BE904865A (fr)	1986-12-03	Derives du phenanthrene, leur procede de preparation et compositions fongicides les contenant.
BE904864A (fr)	1986-12-03	Derives de la quinoleine, leur procede de preparation et compositions pharmaceutiques les contenant.
FR2399417A1 (fr)	1979-03-02	Nouveaux derives de la dibenzo (d,g) (1,3,6)dioxazocine, procedes de preparation de ces derives et medicaments contenant ceux-ci
FR2449689A1 (fr)	1980-09-19	Nouveaux derives condenses de pyrrolidine ou de piperidine, leur procede de preparation et leurs applications en therapeutique
BE904835A (fr)	1986-11-28	Nouveaux derives d'isoquinoleine, leur procede de preparation, leur application en therapeutique et produits intermediaires.
BE1003067A5 (fr)	1991-11-12	Derives de la pyrimidine.
BE905751A (fr)	1987-03-02	Nitro-anthracycline, aglycone correspondante, procedes pour les preparer, composition pharmaceutique correspondante.

Legal Events

Date	Code	Title	Description
1996-12-31	CA	Change of address of the owner of the patent
1996-12-31	CH	Change of patent owner
1996-12-31	CN	Change of patent owner's name
1999-01-31	RE	Patent lapsed	Owner name: PHARMACIA & UPJOHN S.P.A. Effective date: 19980731