ATE512148T1 - Pyrazolo- und imidazopyrimidinderivate - Google Patents

Pyrazolo- und imidazopyrimidinderivate

Info

Publication number: ATE512148T1
Authority: AT; Austria
Prior art keywords: imidazopyrimide; pyrazolo; derivatives; imidazopyrimide derivatives
Prior art date: 2003-10-03

Application number

AT04765633T

Other languages

English (en)

Inventor

Juergen Wichmann

Thomas Woltering

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-10-03

Filing date

2004-09-27

Publication date

2011-06-15

2004-09-27 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

2011-06-15 Application granted granted Critical

2011-06-15 Publication of ATE512148T1 publication Critical patent/ATE512148T1/de

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Psychiatry (AREA)
Addiction (AREA)
Pain & Pain Management (AREA)
Hospice & Palliative Care (AREA)
Virology (AREA)
Physical Education & Sports Medicine (AREA)
Endocrinology (AREA)
Psychology (AREA)
Tropical Medicine & Parasitology (AREA)
Cardiology (AREA)
Molecular Biology (AREA)
AIDS & HIV (AREA)
Ophthalmology & Optometry (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Heart & Thoracic Surgery (AREA)
Otolaryngology (AREA)
Reproductive Health (AREA)
Orthopedic Medicine & Surgery (AREA)
Diabetes (AREA)
Urology & Nephrology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

AT04765633T 2003-10-03 2004-09-27 Pyrazolo- und imidazopyrimidinderivate ATE512148T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP03078075		2003-10-03
PCT/EP2004/010807 WO2005040171A1 (en)	2003-10-03	2004-09-27	Pyrazolo and imidazo-pyrimidine derivatives

Publications (1)

Publication Number	Publication Date
ATE512148T1 true ATE512148T1 (de)	2011-06-15

Family

ID=34486287

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT04765633T ATE512148T1 (de)	2003-10-03	2004-09-27	Pyrazolo- und imidazopyrimidinderivate

Country Status (21)

Country	Link
US (2)	US7329662B2 (de)
EP (1)	EP1670801B1 (de)
JP (1)	JP4551402B2 (de)
KR (2)	KR100781469B1 (de)
CN (2)	CN100522964C (de)
AR (1)	AR045959A1 (de)
AT (1)	ATE512148T1 (de)
AU (1)	AU2004283801B2 (de)
BR (1)	BRPI0414948A (de)
CA (1)	CA2540768C (de)
CO (1)	CO5680437A2 (de)
ES (1)	ES2364753T3 (de)
HK (1)	HK1099302A1 (de)
IL (1)	IL174512A0 (de)
MX (1)	MXPA06003526A (de)
NO (1)	NO20061363L (de)
NZ (1)	NZ546037A (de)
RU (1)	RU2350616C2 (de)
TW (1)	TWI297691B (de)
WO (1)	WO2005040171A1 (de)
ZA (1)	ZA200602677B (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7329662B2 (en) *	2003-10-03	2008-02-12	Hoffmann-La Roche Inc.	Pyrazolo-pyridine
DK1761541T3 (da) *	2004-06-21	2008-04-28	Hoffmann La Roche	Pyrrazolo-pyrimidin-derivater
ES2365406T3 (es)	2005-02-11	2011-10-04	F. Hoffmann-La Roche Ag	Derivados de pirazolo-pirimidina como antagonistas de mglur2.
JP4801724B2 (ja)	2005-03-23	2011-10-26	エフ．ホフマン−ラロシュアーゲー	ｍＧｌｕＲ２アンタゴニストとしてのアセチレニル−ピラゾロ−ピリミジン誘導体
CN101273040B (zh)	2005-09-27	2011-11-09	弗·哈夫曼-拉罗切有限公司	作为mglur2拮抗剂的*二唑基吡唑并嘧啶类化合物
JP2010534206A (ja) *	2007-07-20	2010-11-04	メルク・シャープ・エンド・ドーム・コーポレイション	ピラゾロ［１，５−ａ］ピリミジン誘導体
CN101671336B (zh) *	2009-09-23	2013-11-13	辽宁利锋科技开发有限公司	芳杂环并嘧啶衍生物和类似物及其制备方法和用途
US9447099B2 (en) *	2011-10-04	2016-09-20	Hoffmann-La Roche Inc.	Methods for the preparation of 5-[2-[7 (trifluoromethyl)-5-[4-(trifluoromethyl)phenyl]pyrazolo [1,5-A]pyrimidin-3-yl[ethynyl]-2-pyridinamine
CN104662002A (zh) *	2012-07-27	2015-05-27	比亚尔-珀特拉和Ca股份公司	取代脲类化合物的合成方法
KR20150070187A (ko)	2012-10-23	2015-06-24	에프. 호프만-라 로슈 아게	자폐 장애의 치료를 위한 ｍｇｌｕ２／３ 길항제
MY182036A (en)	2013-02-21	2021-01-18	Sunshine Lake Pharma Co Ltd	Heteroaromatic compounds as pi3 kinase modulators
TW201542550A (zh) *	2013-09-06	2015-11-16	Lexicon Pharmaceuticals Inc	吡唑并［１，５－ａ］嘧啶基化合物、包含彼之組合物以及使用彼之方法
CN104193745B (zh) *	2014-07-30	2016-09-28	斯芬克司药物研发（天津）股份有限公司	一种咪唑并嘧啶羧酸类化合物及其制备方法
AU2015295300B2 (en) *	2014-08-01	2019-05-02	Janssen Pharmaceutica Nv	6,7-dihydropyrazolo[1,5-a]pyrazin-4(5h)-one compounds and their use as negative allosteric modulators of mGluR2 receptors
EP3000814A1 (de)	2014-09-26	2016-03-30	Domain Therapeutics	Substituierte Pyrazolochinazolinone und Pyrrolochinazolinone als allosterische Modulatoren von metabotropen Glutamatrezeptoren der Gruppe II
ES2727158T3 (es) *	2014-12-03	2019-10-14	Janssen Pharmaceutica Nv	Ligandos para PET de mGluR2 radiomarcados
TWI713497B (zh) *	2015-02-26	2020-12-21	南韓商愛思開生物製藥股份有限公司	咪唑并嘧啶及咪唑并三衍生物及包含該衍生物之醫藥組成物
EP3341374A1 (de)	2015-08-26	2018-07-04	Blueprint Medicines Corporation	Verbindungen und zusammensetzungen zur behandlung von störungen im zusammenhang mit ntrk
AR106756A1 (es) *	2015-11-19	2018-02-14	Blueprint Medicines Corp	Compuestos y composiciones útiles para el tratamiento de trastornos relacionados con ntrk
EP3389728B1 (de)	2015-12-18	2020-08-05	Janssen Pharmaceutica NV	Radioaktiv markierte mglur2/3 pet-liganden
CA3003998A1 (en)	2015-12-18	2017-06-22	Janssen Pharmaceutica Nv	Radiolabelled mglur2/3 pet ligands
BR112020014431A2 (pt) *	2018-01-17	2020-12-01	Glaxosmithkline Intellectual Property Development Limited	inibidores de pl4kiiibeta

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN1090189C (zh)	1996-02-07	2002-09-04	詹森药业有限公司	吡唑并嘧啶类化合物
NZ333777A (en) *	1996-07-24	2000-07-28	Du Pont Pharm Co	(1,5-a) pyrazolo and triazole triazines and pyrimidines
ATE214704T1 (de) *	1997-07-18	2002-04-15	Hoffmann La Roche	5h-thiazolo(3,2-a)pyrimidinderivate
WO2000059908A2 (en)	1999-04-06	2000-10-12	Du Pont Pharmaceuticals Company	Pyrazolopyrimidines as crf antagonists
AU2002312788B2 (en)	2001-04-12	2005-11-10	F. Hoffmann-La Roche Ag	Dihydro-benzo [b] [1, 4] diazepin-2-one derivatives as mGluR2 antagonists II
GB0128499D0 (en)	2001-11-28	2002-01-23	Merck Sharp & Dohme	Therapeutic agents
CA2468067A1 (en) *	2001-11-30	2003-06-12	Merck & Co., Inc.	Metabotropic glutamate receptor-5 modulators
US7329662B2 (en) *	2003-10-03	2008-02-12	Hoffmann-La Roche Inc.	Pyrazolo-pyridine

2004
- 2004-09-24 US US10/948,970 patent/US7329662B2/en not_active Expired - Fee Related
- 2004-09-27 EP EP04765633A patent/EP1670801B1/de not_active Expired - Lifetime
- 2004-09-27 AU AU2004283801A patent/AU2004283801B2/en not_active Ceased
- 2004-09-27 KR KR1020067006303A patent/KR100781469B1/ko not_active IP Right Cessation
- 2004-09-27 CA CA2540768A patent/CA2540768C/en not_active Expired - Fee Related
- 2004-09-27 AT AT04765633T patent/ATE512148T1/de active
- 2004-09-27 ES ES04765633T patent/ES2364753T3/es not_active Expired - Lifetime
- 2004-09-27 RU RU2006114749/04A patent/RU2350616C2/ru not_active IP Right Cessation
- 2004-09-27 JP JP2006530027A patent/JP4551402B2/ja not_active Expired - Fee Related
- 2004-09-27 CN CNB2004800357899A patent/CN100522964C/zh not_active Expired - Fee Related
- 2004-09-27 NZ NZ546037A patent/NZ546037A/en unknown
- 2004-09-27 CN CN2008100836319A patent/CN101239981B/zh not_active Expired - Fee Related
- 2004-09-27 MX MXPA06003526A patent/MXPA06003526A/es active IP Right Grant
- 2004-09-27 KR KR1020077018904A patent/KR20070096033A/ko not_active Application Discontinuation
- 2004-09-27 BR BRPI0414948-3A patent/BRPI0414948A/pt not_active IP Right Cessation
- 2004-09-27 WO PCT/EP2004/010807 patent/WO2005040171A1/en active Application Filing
- 2004-09-30 TW TW093129636A patent/TWI297691B/zh active
- 2004-10-01 AR ARP040103565A patent/AR045959A1/es unknown
2006
- 2006-03-23 IL IL174512A patent/IL174512A0/en not_active IP Right Cessation
- 2006-03-24 NO NO20061363A patent/NO20061363L/no not_active Application Discontinuation
- 2006-03-31 ZA ZA200602677A patent/ZA200602677B/en unknown
- 2006-04-03 CO CO06032493A patent/CO5680437A2/es not_active Application Discontinuation
2007
- 2007-02-16 US US11/707,480 patent/US7514443B2/en not_active Expired - Fee Related
- 2007-06-18 HK HK07106520.9A patent/HK1099302A1/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
CA2540768A1 (en)	2005-05-06
KR100781469B1 (ko)	2007-12-03
CA2540768C (en)	2011-08-09
RU2006114749A (ru)	2007-11-20
RU2350616C2 (ru)	2009-03-27
WO2005040171A1 (en)	2005-05-06
CN1890242A (zh)	2007-01-03
ZA200602677B (en)	2007-09-26
KR20060089731A (ko)	2006-08-09
CN101239981A (zh)	2008-08-13
EP1670801A1 (de)	2006-06-21
EP1670801B1 (de)	2011-06-08
BRPI0414948A (pt)	2006-11-07
US20050130992A1 (en)	2005-06-16
US20080051421A1 (en)	2008-02-28
IL174512A0 (en)	2006-08-01
CN100522964C (zh)	2009-08-05
ES2364753T3 (es)	2011-09-13
TWI297691B (en)	2008-06-11
KR20070096033A (ko)	2007-10-01
AR045959A1 (es)	2005-11-16
US7329662B2 (en)	2008-02-12
WO2005040171A8 (en)	2006-08-03
MXPA06003526A (es)	2006-06-08
CO5680437A2 (es)	2006-09-29
HK1099302A1 (en)	2007-08-10
TW200528453A (en)	2005-09-01
AU2004283801A1 (en)	2005-05-06
CN101239981B (zh)	2011-01-19
US7514443B2 (en)	2009-04-07
JP4551402B2 (ja)	2010-09-29
NO20061363L (no)	2006-04-24
AU2004283801B2 (en)	2010-04-22
NZ546037A (en)	2008-09-26
JP2007507446A (ja)	2007-03-29

Publication	Publication Date	Title
IS7872A (is)	2005-05-30	Pýrrólópýrimidín afleiður
ATE481402T1 (de)	2010-10-15	Pyrazolopyridin-derivate
DE602004019294D1 (de)	2009-03-19	Tetrahydronaphthalin- und harnstoffderivate
HK1099302A1 (en)	2007-08-10	Pyrazolo and imidazo-pyrimidine derivatives
ATE340782T1 (de)	2006-10-15	Piperidinbenzolsulfonamidderivate
ATE478870T1 (de)	2010-09-15	Spiroindolinpiperidinderivate
ATE460418T1 (de)	2010-03-15	Heterocyclocarboxamidderivate
DE60330372D1 (de)	2010-01-14	Indol-3-schwefelderivate
ATE467631T1 (de)	2010-05-15	Chinuclidinamidderivate
IS7720A (is)	2005-03-01	Píperidín-N-oxíð-afleiður
ATE438644T1 (de)	2009-08-15	Chinazolinderivate
DK2248807T3 (da)	2013-08-26	N-Phenyl-2-pyrimidinaminderivater
DK1682493T3 (da)	2009-04-20	Amidoacetonitrilderivater
ATE352550T1 (de)	2007-02-15	Chinazolinderivate
DK1606277T3 (da)	2008-08-18	Imidazol-4-yl-ethynyl-pyridinderivater
IS8364A (is)	2006-03-20	N-þíasól-2-ýl-bensamíð afleiður
DK1675852T3 (da)	2009-05-25	Heterocykliske 7-amino-alkylidenyl-quinoloner og -naphthyridoner
DE502004011106D1 (de)	2010-06-10	6-arylmethyl-substituierte pyrazolopyrimidine
DE60307512D1 (de)	2006-09-21	3h-chinazoline -4-on derivaten
ATE423771T1 (de)	2009-03-15	Tetrahydrochinolinderivate
ATE449064T1 (de)	2009-12-15	Amidoacetonitrilderivate
IS8045A (is)	2005-09-26	Púrín-6-ón-afleiður
DE50306277D1 (de)	2007-02-22	4-alkyl-/4-alkenyl-/4-alkinylmethyl/-1-arylcyclohexylamin-derivate
GB0307231D0 (en)	2003-04-30	7-Nitroindoline derivatives and their uses
IS7906A (is)	2005-06-22	Afleiður própargýl-tríflúorómetoxý-amínó-benzóþíazóls

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