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AR019934A1 - Composiciones farmaceuticas con recubrimiento enterico - Google Patents

Composiciones farmaceuticas con recubrimiento enterico

Info

Publication number
AR019934A1
AR019934A1 ARP990103526A ARP990103526A AR019934A1 AR 019934 A1 AR019934 A1 AR 019934A1 AR P990103526 A ARP990103526 A AR P990103526A AR P990103526 A ARP990103526 A AR P990103526A AR 019934 A1 AR019934 A1 AR 019934A1
Authority
AR
Argentina
Prior art keywords
enteric coating
tablets
pharmaceutical compositions
pharmaceutical composition
less
Prior art date
Application number
ARP990103526A
Other languages
English (en)
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of AR019934A1 publication Critical patent/AR019934A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846—Poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Composicion farmacéutica de recubrimiento entérico de alta carga de fármaco que incluye un nucleo en la forma de una tableta y que comprende un medicamentoque es sensible a un medio de pH bajo de menos de 3, tal como ddI (didanosina), y que tiene unrecubrimiento entérico formado de copolímero de ácidometacrílico y un plastificante. Las tabletas pueden ser de diversos tamanos e ingerirse oralmente, individualmente o como una pluralidad de tabletassuficientes para lograr una dosificacion deseadapodrían encapsularse en una cápsula disoluble. Las tabletas tienen una resistencia excelente a ladesintegracion a pH menor de 3 pero tienen propiedades de liberacion del fármaco excelentes a pH mayor de 4,5. También se expone un método para preparardichacomposicion farmacéutica.
ARP990103526A 1998-07-17 1999-07-16 Composiciones farmaceuticas con recubrimiento enterico AR019934A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US11841898A 1998-07-17 1998-07-17

Publications (1)

Publication Number Publication Date
AR019934A1 true AR019934A1 (es) 2002-03-27

Family

ID=22378467

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP990103526A AR019934A1 (es) 1998-07-17 1999-07-16 Composiciones farmaceuticas con recubrimiento enterico

Country Status (35)

Country Link
US (2) US6331316B1 (es)
EP (1) EP1098635B1 (es)
JP (1) JP2002520350A (es)
KR (1) KR100535954B1 (es)
CN (1) CN1195499C (es)
AR (1) AR019934A1 (es)
AT (1) ATE268165T1 (es)
AU (1) AU750388B2 (es)
BG (1) BG65443B1 (es)
BR (1) BR9815948A (es)
CA (1) CA2337885C (es)
CO (1) CO5090840A1 (es)
CZ (1) CZ301557B6 (es)
DE (1) DE69824319T2 (es)
DK (1) DK1098635T3 (es)
EE (1) EE05021B1 (es)
EG (1) EG23944A (es)
ES (1) ES2221188T3 (es)
GE (1) GEP20032912B (es)
HU (1) HU226492B1 (es)
ID (1) ID27019A (es)
IL (1) IL139701A0 (es)
LT (1) LT4844B (es)
LV (1) LV12638B (es)
NO (1) NO330554B1 (es)
NZ (1) NZ508298A (es)
PL (1) PL195587B1 (es)
PT (1) PT1098635E (es)
RO (1) RO121082B1 (es)
RU (1) RU2201217C2 (es)
SK (1) SK285152B6 (es)
TR (1) TR200003577T2 (es)
UA (1) UA73092C2 (es)
WO (1) WO2000003696A1 (es)
ZA (1) ZA993446B (es)

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