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ES2421787T3 - Forma de dosificación de una vez al día de pramipexol - Google Patents

Forma de dosificación de una vez al día de pramipexol

Info

Publication number
ES2421787T3
ES2421787T3 ES10174089T ES10174089T ES2421787T3 ES 2421787 T3 ES2421787 T3 ES 2421787T3 ES 10174089 T ES10174089 T ES 10174089T ES 10174089 T ES10174089 T ES 10174089T ES 2421787 T3 ES2421787 T3 ES 2421787T3
Authority
ES
Spain
Prior art keywords
pramipexole
composition
pharmaceutically acceptable
once
dosage form
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES10174089T
Other languages
English (en)
Other versions
ES2421787T9 (es
Inventor
Ernest J Lee
Gerard M Bredael
John R Baldwin
Steven R Cox
Mark J Heintz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia LLC
Original Assignee
Pharmacia LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=31192088&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2421787(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pharmacia LLC filed Critical Pharmacia LLC
Application granted granted Critical
Publication of ES2421787T3 publication Critical patent/ES2421787T3/es
Publication of ES2421787T9 publication Critical patent/ES2421787T9/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/428—Thiazoles condensed with carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Una composición farmacéutica administrable por vía oral que comprende una cantidad terapéuticamente eficaz depramipexol o una sal farmacéuticamente aceptable del mismo, y al menos un excipiente farmacéuticamenteaceptable, presentando dicha composición (a) un perfil de liberación in vitro en el que, como promedio, no más deaproximadamente un 20% del pramipexol se disuelve en 2 horas después de la colocación de la composición en unensayo de disolución convencional realizado de acuerdo con la USP 24, que usa un Aparato 1 con una velocidad derotación del husillo de 100 rpm y un medio de disolución de tampón de fosfato 0,05 m y un pH de 6,8 a 37 ºC y en laque la composición adquiere la forma de un comprimido que comprende pramipexol o una sal del mismo, dispersoen una matriz que comprende un polímero hidrofílico y almidón.
ES10174089T 2002-07-25 2003-07-25 Forma de dosificación de una vez al día de pramipexol Expired - Lifetime ES2421787T3 (es)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US39844702P 2002-07-25 2002-07-25
US39842702P 2002-07-25 2002-07-25
US398447P 2002-07-25
US398427P 2002-07-25
US47951403P 2003-06-18 2003-06-18
US479514P 2003-06-18

Publications (2)

Publication Number Publication Date
ES2421787T3 true ES2421787T3 (es) 2013-09-05
ES2421787T9 ES2421787T9 (es) 2013-11-06

Family

ID=31192088

Family Applications (2)

Application Number Title Priority Date Filing Date
ES03771959.8T Expired - Lifetime ES2436745T3 (es) 2002-07-25 2003-07-25 Forma de dosificación de pramipexol una vez al día
ES10174089T Expired - Lifetime ES2421787T3 (es) 2002-07-25 2003-07-25 Forma de dosificación de una vez al día de pramipexol

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES03771959.8T Expired - Lifetime ES2436745T3 (es) 2002-07-25 2003-07-25 Forma de dosificación de pramipexol una vez al día

Country Status (40)

Country Link
US (2) US8679533B2 (es)
EP (2) EP1536792B1 (es)
JP (1) JP4607584B2 (es)
KR (2) KR101066374B1 (es)
CN (1) CN1671381B (es)
AP (1) AP2223A (es)
AR (1) AR040682A1 (es)
AU (1) AU2003256921B2 (es)
BR (1) BR0312948A (es)
CA (1) CA2493629C (es)
CU (1) CU23468B7 (es)
CY (2) CY1114263T1 (es)
DE (1) DE20321906U1 (es)
DK (2) DK2289514T5 (es)
EA (1) EA017595B1 (es)
EC (1) ECSP055569A (es)
ES (2) ES2436745T3 (es)
GE (1) GEP20074047B (es)
HK (1) HK1078007A1 (es)
HR (1) HRP20041234B1 (es)
IL (1) IL166076A0 (es)
IS (1) IS7613A (es)
MA (1) MA27372A1 (es)
ME (1) ME00347B (es)
MX (1) MXPA05000980A (es)
MY (1) MY142204A (es)
NO (1) NO20050481L (es)
NZ (1) NZ562681A (es)
OA (1) OA12889A (es)
PA (1) PA8578501A1 (es)
PE (1) PE20040134A1 (es)
PL (1) PL375444A1 (es)
PT (2) PT2289514E (es)
RS (1) RS52764B (es)
SG (1) SG177011A1 (es)
SI (2) SI2289514T1 (es)
TW (1) TWI351955B (es)
UY (1) UY27913A1 (es)
WO (1) WO2004010999A1 (es)
ZA (1) ZA200500015B (es)

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CN105030721B (zh) * 2015-08-30 2018-05-04 南京康川济医药科技有限公司 一种含有盐酸普拉克索的口服固体组合物
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