AP2004003189A0 - Use of CETP inhibitors and optionally HMG COA reductase inhibitors and/or antihypertensive agents. - Google Patents
Use of CETP inhibitors and optionally HMG COA reductase inhibitors and/or antihypertensive agents.Info
- Publication number
- AP2004003189A0 AP2004003189A0 AP2004003189A AP2004003189A AP2004003189A0 AP 2004003189 A0 AP2004003189 A0 AP 2004003189A0 AP 2004003189 A AP2004003189 A AP 2004003189A AP 2004003189 A AP2004003189 A AP 2004003189A AP 2004003189 A0 AP2004003189 A0 AP 2004003189A0
- Authority
- AP
- ARIPO
- Prior art keywords
- inhibitors
- coa reductase
- antihypertensive agents
- hmg coa
- cetp
- Prior art date
Links
- 229940121710 HMGCoA reductase inhibitor Drugs 0.000 title 1
- 229940030600 antihypertensive agent Drugs 0.000 title 1
- 239000002220 antihypertensive agent Substances 0.000 title 1
- 239000003354 cholesterol ester transfer protein inhibitor Substances 0.000 title 1
- 239000002471 hydroxymethylglutaryl coenzyme A reductase inhibitor Substances 0.000 title 1
- 229940096701 plain lipid modifying drug hmg coa reductase inhibitors Drugs 0.000 title 1
Classifications
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4706—4-Aminoquinolines; 8-Aminoquinolines, e.g. chloroquine, primaquine
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- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Immunology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Obesity (AREA)
- Rheumatology (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Vascular Medicine (AREA)
- Pain & Pain Management (AREA)
- Toxicology (AREA)
- Child & Adolescent Psychology (AREA)
- Transplantation (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Ophthalmology & Optometry (AREA)
- Biochemistry (AREA)
- Dermatology (AREA)
- Emergency Medicine (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US39339502P | 2002-07-02 | 2002-07-02 | |
PCT/IB2003/002792 WO2004004778A1 (en) | 2002-07-02 | 2003-06-18 | Use of cetp inhibitors and optionally hmg coa reductable inhibitors and/or antihypertensive agents |
Publications (1)
Publication Number | Publication Date |
---|---|
AP2004003189A0 true AP2004003189A0 (en) | 2004-12-31 |
Family
ID=30115572
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AP2004003189A AP2004003189A0 (en) | 2002-07-02 | 2003-06-18 | Use of CETP inhibitors and optionally HMG COA reductase inhibitors and/or antihypertensive agents. |
Country Status (23)
Country | Link |
---|---|
US (1) | US20040053842A1 (xx) |
EP (1) | EP1519754A1 (xx) |
JP (1) | JP2005532388A (xx) |
KR (1) | KR20050025578A (xx) |
CN (1) | CN1665537A (xx) |
AP (1) | AP2004003189A0 (xx) |
AU (1) | AU2003244921A1 (xx) |
BR (1) | BR0312421A (xx) |
CA (1) | CA2488736A1 (xx) |
EA (1) | EA200401471A1 (xx) |
EC (1) | ECSP045520A (xx) |
HR (1) | HRP20041238A2 (xx) |
IL (1) | IL165328A0 (xx) |
IS (1) | IS7570A (xx) |
MA (1) | MA27311A1 (xx) |
MX (1) | MXPA05000015A (xx) |
NO (1) | NO20050497L (xx) |
OA (1) | OA12876A (xx) |
PL (1) | PL374878A1 (xx) |
TN (1) | TNSN04268A1 (xx) |
TW (1) | TW200401768A (xx) |
WO (1) | WO2004004778A1 (xx) |
ZA (1) | ZA200409582B (xx) |
Families Citing this family (42)
Publication number | Priority date | Publication date | Assignee | Title |
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US7071210B2 (en) * | 2002-07-02 | 2006-07-04 | Pfizer Inc. | CETP inhibitors in combination with antihypertensive agents and uses thereof |
MXPA05005813A (es) * | 2002-12-20 | 2005-12-12 | Pfizer Prod Inc | Formas de dosificacion que comprenden un inhibidor de la cetp y un inhibidor de la hmg-coa reductasa. |
US20040132771A1 (en) * | 2002-12-20 | 2004-07-08 | Pfizer Inc | Compositions of choleseteryl ester transfer protein inhibitors and HMG-CoA reductase inhibitors |
KR20050088190A (ko) * | 2002-12-20 | 2005-09-02 | 화이자 프로덕츠 인코포레이티드 | 콜레스테릴 에스터 전달 단백질 억제제 및 hmg-coa환원 효소 억제제를 포함하는 투약 형태 |
GEP20084540B (en) | 2003-01-14 | 2008-11-25 | Arena Pharm Inc | 1,2,3-trisubstituted aryl and heteroaryl derivatives as modulators of metabolism and the prpphylaxis and treatment of disorders related thereto such as diabetes and hyperglycemia |
JP2006520810A (ja) * | 2003-03-17 | 2006-09-14 | 日本たばこ産業株式会社 | S−[2−([[1−(2−エチルブチル)シクロヘキシル]カルボニル]アミノ)フェニル]2−メチルプロパンチオエートの経口吸収性を増加させる方法 |
ES2377121T3 (es) * | 2003-03-17 | 2012-03-22 | Japan Tobacco Inc. | Composiciones farmacéuticas de inhibidores de CETP |
TWI494102B (zh) * | 2003-05-02 | 2015-08-01 | Japan Tobacco Inc | 包含s-〔2(〔〔1-(2-乙基丁基)環己基〕羰基〕胺基)苯基〕2-甲基丙烷硫酯及hmg輔酶a還原酶抑制劑之組合 |
CN101967117A (zh) * | 2003-05-30 | 2011-02-09 | 兰贝克赛实验室有限公司 | 取代的吡咯衍生物及其作为hmg-co抑制剂的用途 |
CN102417508A (zh) | 2003-07-14 | 2012-04-18 | 艾尼纳制药公司 | 作为新陈代谢调节剂的稠合芳基和杂芳基衍生物以及预防和治疗与其相关的病症 |
WO2005058310A2 (en) * | 2003-12-16 | 2005-06-30 | Novartis Ag | Use of stating for the treatment of metabolic syndrome |
EP1740547A1 (en) * | 2004-04-07 | 2007-01-10 | Millennium Pharmaceuticals, Inc. | Pgd2 receptor antagonists for the treatment of inflammatory diseases |
US20060063803A1 (en) * | 2004-09-23 | 2006-03-23 | Pfizer Inc | 4-Amino substituted-2-substituted-1,2,3,4-tetrahydroquinoline compounds |
US20090208539A1 (en) * | 2004-11-22 | 2009-08-20 | Adel Penhasi | Stable atorvastatin formulations |
JP4954085B2 (ja) * | 2004-12-06 | 2012-06-13 | メディシノバ, インコーポレイテッド | 神経障害性疼痛及びその関連する症状を治療するためのイブジラスト |
US7700774B2 (en) * | 2004-12-20 | 2010-04-20 | Dr. Reddy's Laboratories Ltd. | Heterocyclic compounds and their pharmaceutical compositions |
EP1833466A1 (en) * | 2004-12-28 | 2007-09-19 | Ranbaxy Laboratories Limited | Methods for the preparation of stable pharmaceutical solid dosage forms of atorvastatin and amlodipine |
US8604055B2 (en) * | 2004-12-31 | 2013-12-10 | Dr. Reddy's Laboratories Ltd. | Substituted benzylamino quinolines as cholesterol ester-transfer protein inhibitors |
KR101238525B1 (ko) | 2004-12-31 | 2013-02-28 | 레디 유에스 테라퓨틱스 인코포레이티드 | Cetp 저해제로서의 신규 벤질아민 유도체 |
MY148521A (en) | 2005-01-10 | 2013-04-30 | Arena Pharm Inc | Substituted pyridinyl and pyrimidinyl derivatives as modulators of metabolism and the treatment of disorders related thereto |
WO2007106111A2 (en) * | 2005-07-01 | 2007-09-20 | Elan Pharma International Limited | Nanoparticulate and controlled release compositions comprising nilvadipine |
EP1948600B1 (en) * | 2005-07-05 | 2014-04-16 | The President & Fellows Of Harvard College | Liver targeted conjugates |
JP2009514851A (ja) * | 2005-11-08 | 2009-04-09 | ランバクシー ラボラトリーズ リミテッド | (3r,5r)−7−[2−(4−フルオロフェニル)−5−イソプロピル−3−フェニル−4−[(4−ヒドロキシメチルフェニルアミノ)カルボニル]−ピロール−1−イル]−3,5−ジヒドロキシ−ヘプタン酸ヘミカルシウム塩の製法 |
US20070238716A1 (en) * | 2006-03-14 | 2007-10-11 | Murthy Ayanampudi S R | Statin stabilizing dosage formulations |
WO2007115132A2 (en) * | 2006-03-29 | 2007-10-11 | Guilford F Timothy | Radiopharmaceutical in self-forming liposomal formulation capable of multipath administration including other ingredients |
WO2007116243A2 (en) * | 2006-04-10 | 2007-10-18 | Mintails Limited | Method for treating fibromyalgia and related conditions |
BRPI0714361A2 (pt) * | 2006-07-14 | 2013-03-26 | Ranbaxy Lab Ltd | polimorfo cristalino, composiÇço farmacÊutica contendo o mesmo, mÉtodo para sua preparaÇço e mÉtodo de tratamento |
WO2008094571A1 (en) * | 2007-01-30 | 2008-08-07 | Avigen, Inc. | Methods for treating acute and subchronic pain |
US20080287402A1 (en) * | 2007-05-03 | 2008-11-20 | Johnson Kirk W | Use of a glial attenuator to prevent amplified pain responses caused by glial priming |
WO2008143883A1 (en) * | 2007-05-14 | 2008-11-27 | Synvista Therapeutics, Inc. | Use of haptoglobin genotyping in diagnosis and treatment of defective reverse cholesterol transport (rct) |
WO2009021113A1 (en) * | 2007-08-09 | 2009-02-12 | Holtzman, Jordan, L. | Methods for enhancing glutahione peroxidase activity |
EP2070520A1 (en) | 2007-12-11 | 2009-06-17 | LEK Pharmaceuticals D.D. | Pharmaceutical composition comprising at least one active agent and a binder, which swells in an acidic media |
PE20131371A1 (es) | 2010-09-22 | 2013-11-25 | Arena Pharm Inc | Moduladores del receptor gpr119 y el tratamiento de trastornos relacionados con este |
EP2626351A4 (en) * | 2010-10-04 | 2014-03-12 | Kowa Co | AGENT CAPABLE OF INHIBITING THE EXPRESSION OF LIPID METABOLISM-RELATED MRNA |
JP5964965B2 (ja) | 2011-08-18 | 2016-08-03 | ドクター レディズ ラボラトリーズ リミテッド | コレステリルエステル転送タンパク質(cetp)インヒビターとしての置換複素環式アミン化合物 |
JP6140168B2 (ja) | 2011-09-27 | 2017-05-31 | ドクター レディズ ラボラトリーズ リミテッド | アテローム性動脈硬化症の処置のために有用なコレステリルエステル転送タンパク質(cetp)インヒビターとしての5−ベンジルアミノメチル−6−アミノピラゾロ[3,4−b]ピリジン誘導体 |
KR20220143773A (ko) * | 2014-08-28 | 2022-10-25 | 뉴암스테르담 파마 비.브이. | 콜레스테릴 에스테르 전달 단백질 억제제 및 HMG CoA 환원효소 억제제를 포함한 약제학적 조성물 및 치료적 조합 |
NZ771435A (en) | 2015-01-06 | 2024-08-30 | Arena Pharm Inc | Methods of treating conditions related to the s1p1 receptor |
MA42807A (fr) | 2015-06-22 | 2018-07-25 | Arena Pharm Inc | Sel l-arginine cristallin d'acide (r)-2-(7-(4-cyclopentyl-3-(trifluorométhyl)benzyloxy)-1,2,3,4-tétrahydrocyclo-penta[b]indol-3-yl)acétique (composé 1) pour une utilisation dans des troubles associés au récepteur de s1p1 |
WO2018019911A1 (en) * | 2016-07-27 | 2018-02-01 | Hartis-Pharma Sarl | Therapeutic combinations to treat red blood cell disorders |
MA47504A (fr) | 2017-02-16 | 2019-12-25 | Arena Pharm Inc | Composés et méthodes de traitement de l'angiocholite biliaire primitive |
CN116196314B (zh) * | 2023-05-04 | 2023-08-15 | 广州市妇女儿童医疗中心 | Ri-1或其盐在制备防治胃肠道疾病的药物中的应用 |
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US6144790A (en) * | 1997-02-07 | 2000-11-07 | Bledin; Anthony G | Contact fiber optic impact sensor |
GT199800127A (es) * | 1997-08-29 | 2000-02-01 | Combinaciones terapeuticas. | |
GT199800126A (es) * | 1997-08-29 | 2000-01-29 | Terapia de combinacion. | |
KR20010022385A (ko) * | 1997-08-29 | 2001-03-15 | 실버스타인 아써 에이. | 암로디핀 및 스타틴 화합물을 포함하는 복합 조성물 |
US6197786B1 (en) * | 1998-09-17 | 2001-03-06 | Pfizer Inc | 4-Carboxyamino-2-substituted-1,2,3,4-tetrahydroquinolines |
US6147089A (en) * | 1998-09-17 | 2000-11-14 | Pfizer Inc. | Annulated 4-carboxyamino-2-methyl-1,2,3,4,-tetrahydroquinolines |
US6147090A (en) * | 1998-09-17 | 2000-11-14 | Pfizer Inc. | 4-carboxyamino-2-methyl-1,2,3,4,-tetrahydroquinolines |
GT199900147A (es) * | 1998-09-17 | 1999-09-06 | 1, 2, 3, 4- tetrahidroquinolinas 2-sustituidas 4-amino sustituidas. | |
US6140342A (en) * | 1998-09-17 | 2000-10-31 | Pfizer Inc. | Oxy substituted 4-carboxyamino-2-methyl-1,2,3,4-tetrahydroquinolines |
KR20020012247A (ko) * | 1999-05-27 | 2002-02-15 | 실버스타인 아써 에이. | 암로디핀 및 아토르바스타틴의 상호 전구체 |
HN2000000050A (es) * | 1999-05-27 | 2001-02-02 | Pfizer Prod Inc | Sal mutua de amlodipino y atorvastatina |
US20030092745A1 (en) * | 2000-02-25 | 2003-05-15 | Pfizer Inc. | Combination therapy |
US20020013334A1 (en) * | 2000-06-15 | 2002-01-31 | Robl Jeffrey A. | HMG-CoA reductase inhibitors and method |
HUP0303083A3 (en) * | 2000-08-15 | 2005-05-30 | Pfizer Prod Inc | Pharmaceutical compositions containing therapeutic combination of a cetp inhibitor and atorvastatin and their use |
US6737430B2 (en) * | 2000-11-09 | 2004-05-18 | Pfizer, Inc. | Mutual prodrug of amlodipine and atorvastatin |
WO2002087556A2 (en) * | 2001-04-11 | 2002-11-07 | Atherogenics, Inc. | Probucol monoesters and their use to increase plasma hdl cholesterol levels and improve hdl functionality |
US7071210B2 (en) * | 2002-07-02 | 2006-07-04 | Pfizer Inc. | CETP inhibitors in combination with antihypertensive agents and uses thereof |
-
2003
- 2003-06-10 US US10/459,683 patent/US20040053842A1/en not_active Abandoned
- 2003-06-18 KR KR1020057000061A patent/KR20050025578A/ko not_active Application Discontinuation
- 2003-06-18 OA OA1200400342A patent/OA12876A/en unknown
- 2003-06-18 AU AU2003244921A patent/AU2003244921A1/en not_active Abandoned
- 2003-06-18 EA EA200401471A patent/EA200401471A1/ru unknown
- 2003-06-18 EP EP03738394A patent/EP1519754A1/en not_active Withdrawn
- 2003-06-18 BR BR0312421-5A patent/BR0312421A/pt not_active IP Right Cessation
- 2003-06-18 WO PCT/IB2003/002792 patent/WO2004004778A1/en not_active Application Discontinuation
- 2003-06-18 MX MXPA05000015A patent/MXPA05000015A/es not_active Application Discontinuation
- 2003-06-18 AP AP2004003189A patent/AP2004003189A0/xx unknown
- 2003-06-18 IL IL16532803A patent/IL165328A0/xx unknown
- 2003-06-18 CN CN038155753A patent/CN1665537A/zh active Pending
- 2003-06-18 CA CA002488736A patent/CA2488736A1/en not_active Abandoned
- 2003-06-18 PL PL03374878A patent/PL374878A1/xx not_active Application Discontinuation
- 2003-06-18 JP JP2004519080A patent/JP2005532388A/ja not_active Withdrawn
- 2003-07-01 TW TW092117985A patent/TW200401768A/zh unknown
-
2004
- 2004-11-26 ZA ZA200409582A patent/ZA200409582B/en unknown
- 2004-11-29 IS IS7570A patent/IS7570A/is unknown
- 2004-12-17 MA MA28016A patent/MA27311A1/fr unknown
- 2004-12-30 EC EC2004005520A patent/ECSP045520A/es unknown
- 2004-12-30 HR HR20041238A patent/HRP20041238A2/xx not_active Application Discontinuation
- 2004-12-30 TN TNP2004000268A patent/TNSN04268A1/fr unknown
-
2005
- 2005-01-28 NO NO20050497A patent/NO20050497L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
WO2004004778A1 (en) | 2004-01-15 |
US20040053842A1 (en) | 2004-03-18 |
CN1665537A (zh) | 2005-09-07 |
MA27311A1 (fr) | 2005-05-02 |
PL374878A1 (en) | 2005-11-14 |
ECSP045520A (es) | 2005-03-10 |
MXPA05000015A (es) | 2005-04-08 |
AU2003244921A1 (en) | 2004-01-23 |
EP1519754A1 (en) | 2005-04-06 |
KR20050025578A (ko) | 2005-03-14 |
OA12876A (en) | 2006-09-15 |
NO20050497L (no) | 2005-03-08 |
ZA200409582B (en) | 2006-08-30 |
IL165328A0 (en) | 2006-01-15 |
BR0312421A (pt) | 2005-04-19 |
IS7570A (is) | 2004-11-29 |
TNSN04268A1 (fr) | 2007-03-12 |
JP2005532388A (ja) | 2005-10-27 |
EA200401471A1 (ru) | 2005-06-30 |
TW200401768A (en) | 2004-02-01 |
CA2488736A1 (en) | 2004-01-15 |
HRP20041238A2 (en) | 2005-06-30 |
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