ECSP045520A - Metodos de tratamiento con inhibidores de la ptec y agentes antihipertensivos - Google Patents
Metodos de tratamiento con inhibidores de la ptec y agentes antihipertensivosInfo
- Publication number
- ECSP045520A ECSP045520A EC2004005520A ECSP045520A ECSP045520A EC SP045520 A ECSP045520 A EC SP045520A EC 2004005520 A EC2004005520 A EC 2004005520A EC SP045520 A ECSP045520 A EC SP045520A EC SP045520 A ECSP045520 A EC SP045520A
- Authority
- EC
- Ecuador
- Prior art keywords
- inhibitors
- ptec
- agents
- antihipertensive
- treatment methods
- Prior art date
Links
- 239000003112 inhibitor Substances 0.000 title abstract 4
- 239000003795 chemical substances by application Substances 0.000 title 1
- 102000012336 Cholesterol Ester Transfer Proteins Human genes 0.000 abstract 1
- 108010061846 Cholesterol Ester Transfer Proteins Proteins 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- -1 for example Substances 0.000 abstract 1
- 239000005555 hypertensive agent Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
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- A—HUMAN NECESSITIES
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4706—4-Aminoquinolines; 8-Aminoquinolines, e.g. chloroquine, primaquine
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- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Cardiology (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Obesity (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Rheumatology (AREA)
- Vascular Medicine (AREA)
- Pain & Pain Management (AREA)
- Transplantation (AREA)
- Reproductive Health (AREA)
- Biochemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Child & Adolescent Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Ophthalmology & Optometry (AREA)
- Pulmonology (AREA)
- Toxicology (AREA)
Abstract
Esta invención se refiere a inhibidores de la proteína de transferencia de ésteres de colesterilo (PTEC), a composiciones farmacéuticas que contienen dichos inhibidores, y al uso de dichos inhibidores para tratar ciertas enfermedades/estados, opcionalmente combinados con ciertos agentes terapéuticos, por ejemplo, agentes hipertensivos.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US39339502P | 2002-07-02 | 2002-07-02 |
Publications (1)
Publication Number | Publication Date |
---|---|
ECSP045520A true ECSP045520A (es) | 2005-03-10 |
Family
ID=30115572
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EC2004005520A ECSP045520A (es) | 2002-07-02 | 2004-12-30 | Metodos de tratamiento con inhibidores de la ptec y agentes antihipertensivos |
Country Status (23)
Country | Link |
---|---|
US (1) | US20040053842A1 (es) |
EP (1) | EP1519754A1 (es) |
JP (1) | JP2005532388A (es) |
KR (1) | KR20050025578A (es) |
CN (1) | CN1665537A (es) |
AP (1) | AP2004003189A0 (es) |
AU (1) | AU2003244921A1 (es) |
BR (1) | BR0312421A (es) |
CA (1) | CA2488736A1 (es) |
EA (1) | EA200401471A1 (es) |
EC (1) | ECSP045520A (es) |
HR (1) | HRP20041238A2 (es) |
IL (1) | IL165328A0 (es) |
IS (1) | IS7570A (es) |
MA (1) | MA27311A1 (es) |
MX (1) | MXPA05000015A (es) |
NO (1) | NO20050497L (es) |
OA (1) | OA12876A (es) |
PL (1) | PL374878A1 (es) |
TN (1) | TNSN04268A1 (es) |
TW (1) | TW200401768A (es) |
WO (1) | WO2004004778A1 (es) |
ZA (1) | ZA200409582B (es) |
Families Citing this family (42)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7071210B2 (en) * | 2002-07-02 | 2006-07-04 | Pfizer Inc. | CETP inhibitors in combination with antihypertensive agents and uses thereof |
BR0317521A (pt) * | 2002-12-20 | 2005-11-16 | Pfizer Prod Inc | Formas de dosagem compreendendo um inibidor da cetp e um inibidor da redutase hmg-coa |
US20040132771A1 (en) * | 2002-12-20 | 2004-07-08 | Pfizer Inc | Compositions of choleseteryl ester transfer protein inhibitors and HMG-CoA reductase inhibitors |
JP2006512359A (ja) * | 2002-12-20 | 2006-04-13 | ファイザー・プロダクツ・インク | CETP阻害薬及びHMG−CoA還元酵素阻害薬を含有する剤形 |
MXPA05007485A (es) | 2003-01-14 | 2006-01-30 | Arena Pharm Inc | Derivados de arilo y heteroarilo 1,2,3-trisubstituidos como moduladores del metabolismo y la profilaxis y tratamiento de trastornos relacionados con ello tales como diabetes e hiperglicemia. |
MXPA05009976A (es) * | 2003-03-17 | 2005-11-04 | Japan Tobacco Inc | Metodo para incrementar la biodisponibilidad oral del 2-metilpropantioato de s-[2-([[1- 2-etilbutil) ciclohexil] carbonil] amino) fenilo]. |
KR20080008440A (ko) * | 2003-03-17 | 2008-01-23 | 니뽄 다바코 산교 가부시키가이샤 | Cetp 억제제의 약제학적 조성물 |
TWI494102B (zh) * | 2003-05-02 | 2015-08-01 | Japan Tobacco Inc | 包含s-〔2(〔〔1-(2-乙基丁基)環己基〕羰基〕胺基)苯基〕2-甲基丙烷硫酯及hmg輔酶a還原酶抑制劑之組合 |
RS20050890A (en) * | 2003-05-30 | 2007-12-31 | Ranbaxy Laboratories Limited, | Substituted pyrrole derivatives |
EA010023B1 (ru) | 2003-07-14 | 2008-06-30 | Арена Фармасьютикалз, Инк. | Конденсированные арильные и гетероарильные производные в качестве модуляторов метаболизма и для профилактики и лечения расстройств, связанных с нарушением метаболизма |
US20070275996A1 (en) * | 2003-12-16 | 2007-11-29 | Michele Bortolini | Use of Statins For The Treatment Of Metabolic Syndrome |
UA84749C2 (ru) * | 2004-04-07 | 2008-11-25 | Милленниум Фармасьютикалз, Инк. | Антагонисты рецептора pgd2 для лечения воспалительных заболеваний |
US20060063803A1 (en) * | 2004-09-23 | 2006-03-23 | Pfizer Inc | 4-Amino substituted-2-substituted-1,2,3,4-tetrahydroquinoline compounds |
WO2007115131A2 (en) * | 2006-03-29 | 2007-10-11 | Guilford F Timothy | Liposomal reduced glutathione and 1-arginine, including other ingredient(s) |
AU2005305460B2 (en) * | 2004-11-22 | 2011-04-21 | Dexcel Pharma Technologies Ltd. | Stable atorvastatin formulations |
BRPI0518829A2 (pt) * | 2004-12-06 | 2008-12-09 | Avigen Inc | mÉtodo para o tratamento de dor neuropÁtica e sÍndromes associadas |
WO2006069162A1 (en) * | 2004-12-20 | 2006-06-29 | Reddy Us Therapeutics, Inc. | Novel heterocyclic compounds and their pharmaceutical compositions |
US20080305158A1 (en) * | 2004-12-28 | 2008-12-11 | Ranbaxy Laboratories Limited | Methods For the Preparation of Stable Pharmaceutical Solid Dosage Forms of Atorvastatin and Amlodipine |
JP5096927B2 (ja) * | 2004-12-31 | 2012-12-12 | レディ ユーエス セラピューティックス, インコーポレイテッド | Cetpインヒビターとしての新規ベンジルアミン誘導体 |
US8604055B2 (en) * | 2004-12-31 | 2013-12-10 | Dr. Reddy's Laboratories Ltd. | Substituted benzylamino quinolines as cholesterol ester-transfer protein inhibitors |
MY148521A (en) | 2005-01-10 | 2013-04-30 | Arena Pharm Inc | Substituted pyridinyl and pyrimidinyl derivatives as modulators of metabolism and the treatment of disorders related thereto |
WO2007106111A2 (en) * | 2005-07-01 | 2007-09-20 | Elan Pharma International Limited | Nanoparticulate and controlled release compositions comprising nilvadipine |
US20090162316A1 (en) * | 2005-07-05 | 2009-06-25 | Harvard University | Liver targeted conjugates |
WO2007054896A1 (en) * | 2005-11-08 | 2007-05-18 | Ranbaxy Laboratories Limited | Process for (3r, 5r)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4- [(4-hydroxy methyl phenyl amino) carbonyl]-pyrrol-1-yl]-3, 5-dihydroxy-heptanoic acid hemi calcium salt |
WO2008020314A2 (en) * | 2006-03-14 | 2008-02-21 | Ranbaxy Laboratories Limited | Statin stabilizing dosage formulations |
WO2007116243A2 (en) * | 2006-04-10 | 2007-10-18 | Mintails Limited | Method for treating fibromyalgia and related conditions |
AU2007274724B2 (en) * | 2006-07-14 | 2012-07-26 | Ranbaxy Laboratories Limited | Polymorphic forms of an HMG-CoA reductase inhibitor and uses thereof |
PT2131841E (pt) * | 2007-01-30 | 2012-09-24 | Univ Colorado Regents | Métodos para tratar a dor aguda e sub-crónica |
US20080287402A1 (en) * | 2007-05-03 | 2008-11-20 | Johnson Kirk W | Use of a glial attenuator to prevent amplified pain responses caused by glial priming |
WO2008143883A1 (en) * | 2007-05-14 | 2008-11-27 | Synvista Therapeutics, Inc. | Use of haptoglobin genotyping in diagnosis and treatment of defective reverse cholesterol transport (rct) |
WO2009021113A1 (en) * | 2007-08-09 | 2009-02-12 | Holtzman, Jordan, L. | Methods for enhancing glutahione peroxidase activity |
EP2070520A1 (en) * | 2007-12-11 | 2009-06-17 | LEK Pharmaceuticals D.D. | Pharmaceutical composition comprising at least one active agent and a binder, which swells in an acidic media |
CN103539791B (zh) | 2010-09-22 | 2017-01-11 | 艾尼纳制药公司 | Gpr119 受体调节剂和对与其相关的障碍的治疗 |
US20130225618A1 (en) * | 2010-10-04 | 2013-08-29 | Kowa Co., Ltd. | Agent for inhibiting expression of lipid metabolism related mrna |
CN103827105B (zh) | 2011-08-18 | 2016-08-17 | 雷迪博士实验室有限公司 | 作为胆固醇酯转移蛋白(cetp)抑制剂的取代的杂环胺化合物 |
EP2760864B1 (en) | 2011-09-27 | 2018-01-24 | Dr. Reddy's Laboratories Ltd. | 5-BENZYLAMINOMETHYL-6-AMINOPYRAZOLO[3,4-b]PYRIDINE DERIVATIVES AS CHOLESTERYL ESTER-TRANSFER PROTEIN (CETP) INHIBITORS USEFUL FOR THE TREATMENT OF ATHEROSCLEROSIS |
WO2016032324A1 (en) * | 2014-08-28 | 2016-03-03 | Dezima Pharma B.V. | PHARMACEUTICAL COMPOSITION AND THERAPEUTIC COMBINATION COMPRISING A CHOLESTERYL ESTER TRANSFER PROTEIN INHIBITOR AND HMG CoA REDUCTASE INHIBITORS |
JP6895378B2 (ja) | 2015-01-06 | 2021-06-30 | アリーナ ファーマシューティカルズ, インコーポレイテッド | S1p1受容体に関連する状態の処置方法 |
MA42807A (fr) | 2015-06-22 | 2018-07-25 | Arena Pharm Inc | Sel l-arginine cristallin d'acide (r)-2-(7-(4-cyclopentyl-3-(trifluorométhyl)benzyloxy)-1,2,3,4-tétrahydrocyclo-penta[b]indol-3-yl)acétique (composé 1) pour une utilisation dans des troubles associés au récepteur de s1p1 |
US20190167767A1 (en) * | 2016-07-27 | 2019-06-06 | Hartis-Pharma Sa | Therapeutic combinations to treat red blood cell disorders |
KR20190116416A (ko) | 2017-02-16 | 2019-10-14 | 아레나 파마슈티칼스, 인크. | 원발 담즙성 담관염을 치료하기 위한 화합물 및 방법 |
CN116196314B (zh) * | 2023-05-04 | 2023-08-15 | 广州市妇女儿童医疗中心 | Ri-1或其盐在制备防治胃肠道疾病的药物中的应用 |
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US6144790A (en) * | 1997-02-07 | 2000-11-07 | Bledin; Anthony G | Contact fiber optic impact sensor |
GT199800127A (es) * | 1997-08-29 | 2000-02-01 | Combinaciones terapeuticas. | |
SK1392000A3 (en) * | 1997-08-29 | 2000-08-14 | Pfizer Prod Inc | Combination therapy comprising amlodipine and a statin compound |
GT199800126A (es) * | 1997-08-29 | 2000-01-29 | Terapia de combinacion. | |
US6140342A (en) * | 1998-09-17 | 2000-10-31 | Pfizer Inc. | Oxy substituted 4-carboxyamino-2-methyl-1,2,3,4-tetrahydroquinolines |
US6147090A (en) * | 1998-09-17 | 2000-11-14 | Pfizer Inc. | 4-carboxyamino-2-methyl-1,2,3,4,-tetrahydroquinolines |
US6197786B1 (en) * | 1998-09-17 | 2001-03-06 | Pfizer Inc | 4-Carboxyamino-2-substituted-1,2,3,4-tetrahydroquinolines |
GT199900147A (es) * | 1998-09-17 | 1999-09-06 | 1, 2, 3, 4- tetrahidroquinolinas 2-sustituidas 4-amino sustituidas. | |
US6147089A (en) * | 1998-09-17 | 2000-11-14 | Pfizer Inc. | Annulated 4-carboxyamino-2-methyl-1,2,3,4,-tetrahydroquinolines |
HN2000000050A (es) * | 1999-05-27 | 2001-02-02 | Pfizer Prod Inc | Sal mutua de amlodipino y atorvastatina |
BR0011006A (pt) * | 1999-05-27 | 2002-02-19 | Pfizer Prod Inc | Prõ-drogas mútuas de amlodipina e atorvastatina |
US20030092745A1 (en) * | 2000-02-25 | 2003-05-15 | Pfizer Inc. | Combination therapy |
US20020013334A1 (en) * | 2000-06-15 | 2002-01-31 | Robl Jeffrey A. | HMG-CoA reductase inhibitors and method |
DZ3409A1 (fr) * | 2000-08-15 | 2002-02-21 | Pfizer Prod Inc | Association therapeuthique |
US6737430B2 (en) * | 2000-11-09 | 2004-05-18 | Pfizer, Inc. | Mutual prodrug of amlodipine and atorvastatin |
CA2444429A1 (en) * | 2001-04-11 | 2002-11-07 | Atherogenics, Inc. | Probucol monoesters and their use to increase plasma hdl cholesterol levels and improve hdl functionality |
US7071210B2 (en) * | 2002-07-02 | 2006-07-04 | Pfizer Inc. | CETP inhibitors in combination with antihypertensive agents and uses thereof |
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2003
- 2003-06-10 US US10/459,683 patent/US20040053842A1/en not_active Abandoned
- 2003-06-18 AU AU2003244921A patent/AU2003244921A1/en not_active Abandoned
- 2003-06-18 KR KR1020057000061A patent/KR20050025578A/ko not_active Application Discontinuation
- 2003-06-18 OA OA1200400342A patent/OA12876A/en unknown
- 2003-06-18 AP AP2004003189A patent/AP2004003189A0/xx unknown
- 2003-06-18 BR BR0312421-5A patent/BR0312421A/pt not_active IP Right Cessation
- 2003-06-18 EA EA200401471A patent/EA200401471A1/ru unknown
- 2003-06-18 PL PL03374878A patent/PL374878A1/xx not_active Application Discontinuation
- 2003-06-18 MX MXPA05000015A patent/MXPA05000015A/es not_active Application Discontinuation
- 2003-06-18 WO PCT/IB2003/002792 patent/WO2004004778A1/en not_active Application Discontinuation
- 2003-06-18 IL IL16532803A patent/IL165328A0/xx unknown
- 2003-06-18 EP EP03738394A patent/EP1519754A1/en not_active Withdrawn
- 2003-06-18 CN CN038155753A patent/CN1665537A/zh active Pending
- 2003-06-18 CA CA002488736A patent/CA2488736A1/en not_active Abandoned
- 2003-06-18 JP JP2004519080A patent/JP2005532388A/ja not_active Withdrawn
- 2003-07-01 TW TW092117985A patent/TW200401768A/zh unknown
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2004
- 2004-11-26 ZA ZA200409582A patent/ZA200409582B/en unknown
- 2004-11-29 IS IS7570A patent/IS7570A/is unknown
- 2004-12-17 MA MA28016A patent/MA27311A1/fr unknown
- 2004-12-30 HR HR20041238A patent/HRP20041238A2/xx not_active Application Discontinuation
- 2004-12-30 EC EC2004005520A patent/ECSP045520A/es unknown
- 2004-12-30 TN TNP2004000268A patent/TNSN04268A1/fr unknown
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2005
- 2005-01-28 NO NO20050497A patent/NO20050497L/no not_active Application Discontinuation
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KR20050025578A (ko) | 2005-03-14 |
ZA200409582B (en) | 2006-08-30 |
AU2003244921A1 (en) | 2004-01-23 |
WO2004004778A1 (en) | 2004-01-15 |
PL374878A1 (en) | 2005-11-14 |
MA27311A1 (fr) | 2005-05-02 |
CA2488736A1 (en) | 2004-01-15 |
MXPA05000015A (es) | 2005-04-08 |
EA200401471A1 (ru) | 2005-06-30 |
TNSN04268A1 (fr) | 2007-03-12 |
US20040053842A1 (en) | 2004-03-18 |
OA12876A (en) | 2006-09-15 |
TW200401768A (en) | 2004-02-01 |
EP1519754A1 (en) | 2005-04-06 |
JP2005532388A (ja) | 2005-10-27 |
IS7570A (is) | 2004-11-29 |
CN1665537A (zh) | 2005-09-07 |
NO20050497L (no) | 2005-03-08 |
BR0312421A (pt) | 2005-04-19 |
IL165328A0 (en) | 2006-01-15 |
HRP20041238A2 (en) | 2005-06-30 |
AP2004003189A0 (en) | 2004-12-31 |
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