NO20041411L - 2-amino-6-(2,4,5 -substituerte-fenyl)-pyridiner for anvendelse som nitrogenoksyd syntase inhibitorer - Google Patents

2-amino-6-(2,4,5 -substituerte-fenyl)-pyridiner for anvendelse som nitrogenoksyd syntase inhibitorer

Info

Publication number: NO20041411L
Authority: NO; Norway
Prior art keywords: phenyl; pyridin; methoxy; ethyl; nitric oxide
Prior art date: 2001-10-10

Application number

NO20041411A

Other languages

English (en)

Norwegian (no)

Inventor

Iii John Adams Lowe

Robert Alfred Volkmann

Original Assignee

Pfizer Prod Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-10-10

Filing date

2004-04-02

Publication date

2004-04-02

2004-04-02 Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc

2004-04-02 Publication of NO20041411L publication Critical patent/NO20041411L/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/73—Unsubstituted amino or imino radicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
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- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Diabetes (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Addiction (AREA)
Hematology (AREA)
Hospice & Palliative Care (AREA)
Reproductive Health (AREA)
Rheumatology (AREA)
Ophthalmology & Optometry (AREA)
Psychology (AREA)
Endocrinology (AREA)
Virology (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Heart & Thoracic Surgery (AREA)
Gynecology & Obstetrics (AREA)
Emergency Medicine (AREA)
Urology & Nephrology (AREA)
Tropical Medicine & Parasitology (AREA)
AIDS & HIV (AREA)
Vascular Medicine (AREA)
Otolaryngology (AREA)

NO20041411A 2001-10-10 2004-04-02 2-amino-6-(2,4,5 -substituerte-fenyl)-pyridiner for anvendelse som nitrogenoksyd syntase inhibitorer NO20041411L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US32825301P	2001-10-10	2001-10-10
PCT/IB2002/003939 WO2003030993A1 (fr)	2001-10-10	2002-09-24	2-amino-6-(2,4,5-substitue-phenyl)-pyridines destinees a etre utilisees en tant qu'inhibiteurs de la synthase d'oxyde nitrique

Publications (1)

Publication Number	Publication Date
NO20041411L true NO20041411L (no)	2004-04-02

Family

ID=23280189

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20041411A NO20041411L (no)	2001-10-10	2004-04-02	2-amino-6-(2,4,5 -substituerte-fenyl)-pyridiner for anvendelse som nitrogenoksyd syntase inhibitorer

Country Status (36)

Country	Link
EP (1)	EP1434624B1 (fr)
JP (1)	JP2005506337A (fr)
KR (1)	KR20040053157A (fr)
CN (1)	CN1568207A (fr)
AP (1)	AP2004003003A0 (fr)
AR (1)	AR036763A1 (fr)
AT (1)	ATE344089T1 (fr)
BG (1)	BG108669A (fr)
BR (1)	BR0213193A (fr)
CA (1)	CA2463364A1 (fr)
CZ (1)	CZ2004450A3 (fr)
DE (1)	DE60215837T2 (fr)
DO (1)	DOP2002000467A (fr)
EA (1)	EA007074B1 (fr)
EC (1)	ECSP045055A (fr)
EE (1)	EE200400085A (fr)
ES (1)	ES2275917T3 (fr)
GT (1)	GT200200206A (fr)
HN (1)	HN2002000289A (fr)
HR (1)	HRP20040260A2 (fr)
HU (1)	HUP0401678A3 (fr)
IL (1)	IL161089A0 (fr)
IS (1)	IS7171A (fr)
MA (1)	MA27074A1 (fr)
MX (1)	MXPA04002313A (fr)
NO (1)	NO20041411L (fr)
NZ (1)	NZ531591A (fr)
OA (1)	OA12664A (fr)
PA (1)	PA8556101A1 (fr)
PE (1)	PE20030478A1 (fr)
PL (1)	PL369454A1 (fr)
SK (1)	SK1642004A3 (fr)
TN (1)	TNSN04057A1 (fr)
UY (1)	UY27476A1 (fr)
WO (1)	WO2003030993A1 (fr)
ZA (1)	ZA200401747B (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20030232739A1 (en) *	2001-08-15	2003-12-18	Pfizer Inc.	Pharmaceutical combinations comprising a NOS inhibitor and an NMDA receptor antagonist
WO2006087577A2 (fr) *	2005-02-21	2006-08-24	Proximagen Ltd.	Inhibition ou traitement de la dyskinesie
JP5886873B2 (ja) *	2010-12-24	2016-03-16	メルク・シャープ・エンド・ドーム・ベー・フェー	Ｎ置換アゼチジン誘導体
RU2637503C1 (ru) *	2016-12-30	2017-12-05	Федеральное государственное автономное образовательное учреждение высшего образования "Национальный исследовательский Томский государственный университет" (ТГУ, НИ ТГУ)	Способ получения n2-метилдезоксигуанозина

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CZ291647B6 (cs) *	1996-03-29	2003-04-16	Pfizer Inc.	6-Fenylpyridyl-2-aminové deriváty, jejich použití a farmaceutické kompozice na jejich bázi
JP3505189B2 (ja) *	1997-02-10	2004-03-08	ファイザー・プロダクツ・インク	２−アミノ−６−（２−置換−４−フェノキシ）−置換ピリジン
CN1617743A (zh) *	1999-05-21	2005-05-18	辉瑞产品公司	用于一氧化氮合酶抑制剂的新药物联合应用

2002
- 2002-09-23 DO DO2002000467A patent/DOP2002000467A/es unknown
- 2002-09-24 IL IL16108902A patent/IL161089A0/xx unknown
- 2002-09-24 EE EEP200400085A patent/EE200400085A/xx unknown
- 2002-09-24 WO PCT/IB2002/003939 patent/WO2003030993A1/fr active IP Right Grant
- 2002-09-24 PL PL02369454A patent/PL369454A1/xx not_active Application Discontinuation
- 2002-09-24 AP APAP/P/2004/003003A patent/AP2004003003A0/en unknown
- 2002-09-24 AT AT02775016T patent/ATE344089T1/de not_active IP Right Cessation
- 2002-09-24 MX MXPA04002313A patent/MXPA04002313A/es active IP Right Grant
- 2002-09-24 EA EA200400321A patent/EA007074B1/ru not_active IP Right Cessation
- 2002-09-24 JP JP2003534022A patent/JP2005506337A/ja not_active Withdrawn
- 2002-09-24 NZ NZ531591A patent/NZ531591A/en unknown
- 2002-09-24 KR KR10-2004-7005248A patent/KR20040053157A/ko not_active Application Discontinuation
- 2002-09-24 HU HU0401678A patent/HUP0401678A3/hu unknown
- 2002-09-24 DE DE60215837T patent/DE60215837T2/de not_active Expired - Fee Related
- 2002-09-24 CN CNA028200675A patent/CN1568207A/zh active Pending
- 2002-09-24 SK SK164-2004A patent/SK1642004A3/sk not_active Application Discontinuation
- 2002-09-24 CA CA002463364A patent/CA2463364A1/fr not_active Abandoned
- 2002-09-24 ES ES02775016T patent/ES2275917T3/es not_active Expired - Lifetime
- 2002-09-24 OA OA1200400093A patent/OA12664A/en unknown
- 2002-09-24 CZ CZ2004450A patent/CZ2004450A3/cs unknown
- 2002-09-24 EP EP02775016A patent/EP1434624B1/fr not_active Expired - Lifetime
- 2002-09-24 BR BR0213193-5A patent/BR0213193A/pt not_active IP Right Cessation
- 2002-10-04 PE PE2002000987A patent/PE20030478A1/es not_active Application Discontinuation
- 2002-10-08 AR ARP020103790A patent/AR036763A1/es unknown
- 2002-10-08 UY UY27476A patent/UY27476A1/es not_active Application Discontinuation
- 2002-10-09 HN HN2002000289A patent/HN2002000289A/es unknown
- 2002-10-10 PA PA20028556101A patent/PA8556101A1/es unknown
- 2002-10-10 GT GT200200206A patent/GT200200206A/es unknown
2004
- 2004-03-03 ZA ZA200401747A patent/ZA200401747B/en unknown
- 2004-03-04 IS IS7171A patent/IS7171A/is unknown
- 2004-03-17 HR HRP20040260 patent/HRP20040260A2/hr not_active Application Discontinuation
- 2004-04-02 NO NO20041411A patent/NO20041411L/no unknown
- 2004-04-06 BG BG108669A patent/BG108669A/xx unknown
- 2004-04-07 TN TNP2004000057A patent/TNSN04057A1/fr unknown
- 2004-04-08 EC EC2004005055A patent/ECSP045055A/es unknown
- 2004-04-08 MA MA27619A patent/MA27074A1/fr unknown

Also Published As

Publication number	Publication date
IL161089A0 (en)	2004-08-31
AR036763A1 (es)	2004-09-29
CZ2004450A3 (cs)	2005-03-16
EP1434624A1 (fr)	2004-07-07
DE60215837D1 (de)	2006-12-14
ZA200401747B (en)	2005-03-03
DOP2002000467A (es)	2003-04-15
HRP20040260A2 (en)	2004-12-31
ES2275917T3 (es)	2007-06-16
PL369454A1 (en)	2005-04-18
MA27074A1 (fr)	2004-12-20
BG108669A (en)	2005-03-31
CN1568207A (zh)	2005-01-19
PA8556101A1 (es)	2003-07-28
BR0213193A (pt)	2004-08-31
WO2003030993A1 (fr)	2003-04-17
GT200200206A (es)	2003-05-23
AP2004003003A0 (en)	2004-03-31
EE200400085A (et)	2004-08-16
OA12664A (en)	2006-06-19
CA2463364A1 (fr)	2003-04-17
EA200400321A1 (ru)	2004-08-26
HUP0401678A2 (hu)	2004-12-28
ATE344089T1 (de)	2006-11-15
NZ531591A (en)	2006-04-28
SK1642004A3 (sk)	2005-04-01
DE60215837T2 (de)	2007-05-16
UY27476A1 (es)	2003-05-30
EA007074B1 (ru)	2006-06-30
HUP0401678A3 (en)	2007-05-02
JP2005506337A (ja)	2005-03-03
EP1434624B1 (fr)	2006-11-02
KR20040053157A (ko)	2004-06-23
ECSP045055A (es)	2004-05-28
MXPA04002313A (es)	2005-04-08
PE20030478A1 (es)	2003-06-06
TNSN04057A1 (fr)	2006-06-01
HN2002000289A (es)	2002-12-03
IS7171A (is)	2004-03-04

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HK1062440A1 (en)	2004-11-05	Heteroaryl ureas containing nitrogen hetero-atoms as p38 kinase inhibitors
NO20065948L (no)	2007-01-23	Quinazolin-4-yl-piperidin- and cinnolin-4-yl-piperidin-derivatives som PDE10-inhibitorer for behandling av CNS forstyrrelser
MY143466A (en)	2011-05-31	Inhibitors of tyrosine kinases
WO2003087088A3 (fr)	2004-01-08	Nouveaux composes
CA2493633A1 (fr)	2004-02-05	Inhibiteurs de kinases
ES2195785A1 (es)	2003-12-01	Nuevos derivados de piridazin-3(2h)-ona.
TR199901917T2 (xx)	1999-12-21	2-Amino-6-(2-ikame edilmi�-4-fenoksi)-ikame edilmi� piridinler
NO20071915L (no)	2007-05-18	Diaminotriazolforbindelser nyttige som proteinkinaseinhibitorer
IL196543A (en)	2013-09-30	Pyridazinone derivatives, pharmaceutical preparations containing them for use in the treatment of disorders
HK1065033A1 (en)	2005-02-08	Thiazole compounds useful as inhibitors or proteinkinases
NO20054359L (no)	2005-10-19	Cykliske protein tyrosin kinase inhibitorer
GB0124933D0 (en)	2001-12-05	Chemical compounds
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