NO20023516L - Antibakterielle 3-aminokinazolinon-2,4-dioner - Google Patents

Antibakterielle 3-aminokinazolinon-2,4-dioner

Info

Publication number: NO20023516L
Authority: NO; Norway
Prior art keywords: aminoquinazolinone; dione; antibacterial
Prior art date: 2000-01-24

Application number

NO20023516A

Other languages

English (en)

Other versions

NO20023516D0 (no

Inventor

Paul Bird

Edmund Lee Ellsworth

Dai Quoc Nguyen

Joseph Peter Sanchez

Howard Daniel Hollis Showalter

Rajeshwar Singh

Michael Andrew Stier

Tuan Phong Tran

Brian Morgan Watson

Judy Yip

Original Assignee

Warner Lambert Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-01-24

Filing date

2002-07-23

Publication date

2002-07-23

2002-07-23 Application filed by Warner Lambert Co filed Critical Warner Lambert Co

2002-07-23 Publication of NO20023516L publication Critical patent/NO20023516L/no

2002-07-23 Publication of NO20023516D0 publication Critical patent/NO20023516D0/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
- C07D239/96—Two oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/10—Spiro-condensed systems

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Oncology (AREA)
Pharmacology & Pharmacy (AREA)
Communicable Diseases (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Veterinary Medicine (AREA)
Virology (AREA)
Molecular Biology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Paper (AREA)

NO20023516A 2000-01-24 2002-07-23 Antibakterielle 3-aminokinazolinon-2,4-dioner NO20023516D0 (no)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US17825200P	2000-01-24	2000-01-24
US24126700P	2000-10-18	2000-10-18
PCT/US2000/033656 WO2001053273A1 (en)	2000-01-24	2000-12-12	3-aminoquinazolin-2,4-dione antibacterial agents

Publications (2)

Publication Number	Publication Date
NO20023516L true NO20023516L (no)	2002-07-23
NO20023516D0 NO20023516D0 (no)	2002-07-23

Family

ID=26874138

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20023516A NO20023516D0 (no)	2000-01-24	2002-07-23	Antibakterielle 3-aminokinazolinon-2,4-dioner

Country Status (38)

Country	Link
US (2)	US7094780B1 (no)
EP (1)	EP1255739B1 (no)
JP (1)	JP4811978B2 (no)
KR (1)	KR20020067701A (no)
CN (1)	CN1425008A (no)
AP (1)	AP2002002603A0 (no)
AR (1)	AR030186A1 (no)
AT (1)	ATE398110T1 (no)
AU (1)	AU783078B2 (no)
BG (1)	BG107023A (no)
BR (1)	BR0017010A (no)
CA (1)	CA2393802C (no)
CO (1)	CO5320600A1 (no)
CR (1)	CR6709A (no)
DE (1)	DE60039194D1 (no)
EA (1)	EA005585B1 (no)
EE (1)	EE200200412A (no)
ES (1)	ES2304992T3 (no)
GE (1)	GEP20053429B (no)
HK (1)	HK1054237A1 (no)
HN (1)	HN2001000009A (no)
HR (1)	HRP20020696A2 (no)
HU (1)	HUP0204101A3 (no)
IL (1)	IL150393A0 (no)
IS (1)	IS6448A (no)
MA (1)	MA26866A1 (no)
MX (1)	MXPA02005989A (no)
NO (1)	NO20023516D0 (no)
OA (1)	OA12316A (no)
PA (1)	PA8510101A1 (no)
PE (1)	PE20011060A1 (no)
PL (1)	PL356837A1 (no)
SK (1)	SK10572002A3 (no)
SV (1)	SV2001000288A (no)
TN (1)	TNSN01011A1 (no)
UY (1)	UY26551A1 (no)
WO (1)	WO2001053273A1 (no)
YU (1)	YU55902A (no)

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WO2002102793A2 (en) *	2001-06-19	2002-12-27	Warner-Lambert Company Llc	Quinazolinediones as antibacterial agents
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JP2007505096A (ja) *	2003-09-12	2007-03-08	ワーナー−ランバートカンパニーリミティドライアビリティーカンパニー	キノロン抗菌剤
WO2005026153A1 (en) *	2003-09-12	2005-03-24	Warner-Lambert Company Llc	Quinazoline-2, 4-diones as antibacterial agents
JP2007511597A (ja) *	2003-11-18	2007-05-10	ワーナー−ランバートカンパニーリミテッドライアビリティーカンパニー	抗菌アミノキナゾリヂンヂオン誘導体
WO2006019965A2 (en) *	2004-07-16	2006-02-23	Takeda San Diego, Inc.	Dipeptidyl peptidase inhibitors
GB0416730D0 (en)	2004-07-27	2004-09-01	Novartis Ag	Organic compounds
ATE447572T1 (de) *	2005-01-26	2009-11-15	Hoffmann La Roche	Phenylmethanonderivate und ihre verwendung als glycin-transporter-1-hemmer
GB0507298D0 (en)	2005-04-11	2005-05-18	Novartis Ag	Organic compounds
US7977346B2 (en)	2006-01-17	2011-07-12	Guoqing Paul Chen	Spiro compounds and methods of use
PT2001862E (pt)	2006-03-28	2011-07-20	Warner Chilcott Co Llc	Sais de malato e polimorfos do ácido (3s,5s)-7-[3- amino-5-metil-piperidinil]-1-ciclopropil-1,4-dihidro- 8-metoxi-4-oxo-3-quinolinocarboxílico
CA2647454A1 (en)	2006-03-28	2007-10-04	The Procter & Gamble Company	A coupling process for preparing quinolone intermediates
US20080139574A1 (en)	2006-11-30	2008-06-12	Cadila Healthcare Limited	Novel quinoline derivatives
AU2009209811B2 (en) *	2008-01-30	2011-07-21	Shin Poong Pharmaceutical Co., Ltd.	Novel quinazoline-2,4-dione derivative, and medical compositions for the prophylaxis and treatment of cranial nerve disease containing the same
WO2011031745A1 (en)	2009-09-09	2011-03-17	Achaogen, Inc.	Antibacterial fluoroquinolone analogs
WO2012088266A2 (en)	2010-12-22	2012-06-28	Incyte Corporation	Substituted imidazopyridazines and benzimidazoles as inhibitors of fgfr3
AR085806A1 (es)	2011-03-15	2013-10-30	Trius Therapeutics Inc	Inhibidores triciclicos de girasa
RU2618673C2 (ru) *	2011-12-21	2017-05-10	Цзянсу Хэнжуй Медсин Ко., Лтд.	Производные пирролопиримидина, полезные в качестве ингибиторов jak-киназы
SI3495367T1 (sl)	2012-06-13	2021-01-29	Incyte Holdings Corporation	Substituirane triciklične spojine kot zaviralci FGFR
US9388185B2 (en)	2012-08-10	2016-07-12	Incyte Holdings Corporation	Substituted pyrrolo[2,3-b]pyrazines as FGFR inhibitors
CN105189505B (zh)	2012-09-12	2019-03-22	默克夏普&多梅有限公司	用作抗菌剂的三环促旋酶抑制剂
US9266892B2 (en)	2012-12-19	2016-02-23	Incyte Holdings Corporation	Fused pyrazoles as FGFR inhibitors
JP6449244B2 (ja)	2013-04-19	2019-01-09	インサイト・ホールディングス・コーポレイションＩｎｃｙｔｅＨｏｌｄｉｎｇｓＣｏｒｐｏｒａｔｉｏｎ	Ｆｇｆｒ抑制剤としての二環式複素環
US10851105B2 (en)	2014-10-22	2020-12-01	Incyte Corporation	Bicyclic heterocycles as FGFR4 inhibitors
MA41551A (fr)	2015-02-20	2017-12-26	Incyte Corp	Hétérocycles bicycliques utilisés en tant qu'inhibiteurs de fgfr4
AU2016219822B2 (en)	2015-02-20	2020-07-09	Incyte Holdings Corporation	Bicyclic heterocycles as FGFR inhibitors
US9580423B2 (en)	2015-02-20	2017-02-28	Incyte Corporation	Bicyclic heterocycles as FGFR4 inhibitors
CN108530448A (zh) *	2017-03-02	2018-09-14	浙江司太立制药股份有限公司	含有碱性氮杂螺环片段的苯并噻嗪-4-酮类化合物及其制备方法
AR111960A1 (es)	2017-05-26	2019-09-04	Incyte Corp	Formas cristalinas de un inhibidor de fgfr y procesos para su preparación
US11466004B2 (en)	2018-05-04	2022-10-11	Incyte Corporation	Solid forms of an FGFR inhibitor and processes for preparing the same
EA202092649A1 (ru)	2018-05-04	2021-06-21	Инсайт Корпорейшн	Соли ингибитора fgfr
CN111620866A (zh) *	2019-02-27	2020-09-04	南京药石科技股份有限公司	一种顺式-7,7-二氟-六氢-1H 吡咯并[3,4-c]吡啶衍生物及其制备方法
US11628162B2 (en)	2019-03-08	2023-04-18	Incyte Corporation	Methods of treating cancer with an FGFR inhibitor
WO2021007269A1 (en)	2019-07-09	2021-01-14	Incyte Corporation	Bicyclic heterocycles as fgfr inhibitors
WO2021067374A1 (en)	2019-10-01	2021-04-08	Incyte Corporation	Bicyclic heterocycles as fgfr inhibitors
AU2020366006A1 (en)	2019-10-14	2022-04-21	Incyte Corporation	Bicyclic heterocycles as FGFR inhibitors
WO2021076728A1 (en)	2019-10-16	2021-04-22	Incyte Corporation	Bicyclic heterocycles as fgfr inhibitors
CN115151539A (zh)	2019-12-04	2022-10-04	因赛特公司	Fgfr抑制剂的衍生物
JP2023505258A (ja)	2019-12-04	2023-02-08	インサイト・コーポレイション	Ｆｇｆｒ阻害剤としての三環式複素環
US12012409B2 (en)	2020-01-15	2024-06-18	Incyte Corporation	Bicyclic heterocycles as FGFR inhibitors
CN111499513B (zh) *	2020-04-24	2023-03-14	上海毕得医药科技股份有限公司	一种2,3,4,5-四溴苯甲酸酯的合成方法
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AR126102A1 (es)	2021-06-09	2023-09-13	Incyte Corp	Heterociclos tricíclicos como inhibidores de fgfr

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DE1068263B (no) *		1959-11-05
FR1203542A (fr) *	1958-02-25	1960-01-19	Rhone Poulenc Sa	Nouveaux dérivés de la phénothiazine comportant en position 10 une chaîne pipérazinique et leurs procédés de préparation
ATE8626T1 (de) *	1980-03-10	1984-08-15	Berri-Balzac Societe Dite:	3-amino-(1h,3h)-2,4-chinazolindionderivate.
GB2097784A (en) *	1981-04-28	1982-11-10	Davidson Dr John Stirton	Dihydrobenzotriazepine diones; aminoquinazoline diones
WO1994014809A1 (de)	1992-12-23	1994-07-07	Byk Gulden Lomberg Chemische Fabrik Gmbh	Anellierte uracilderivate
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PL344248A1 (en) *	1998-05-26	2001-10-22	Warner Lambert Co	Bicyclic pyrimidines and bicyclic 3,4-dihydropyrimidines as inhibitors of cellular proliferation
TR200101644T2 (tr) *	1998-12-11	2001-11-21	F.Hoffmann-La Roche Ag	TNF-ALFA önleyicileri olarak siklik hidrazin türevleri.

2000
- 2000-12-12 US US10/182,221 patent/US7094780B1/en not_active Expired - Fee Related
- 2000-12-12 PL PL00356837A patent/PL356837A1/xx not_active Application Discontinuation
- 2000-12-12 EE EEP200200412A patent/EE200200412A/xx unknown
- 2000-12-12 CN CN00818578A patent/CN1425008A/zh active Pending
- 2000-12-12 MX MXPA02005989A patent/MXPA02005989A/es active IP Right Grant
- 2000-12-12 YU YU55902A patent/YU55902A/sh unknown
- 2000-12-12 CA CA2393802A patent/CA2393802C/en not_active Expired - Fee Related
- 2000-12-12 AT AT00984246T patent/ATE398110T1/de not_active IP Right Cessation
- 2000-12-12 EP EP00984246A patent/EP1255739B1/en not_active Expired - Lifetime
- 2000-12-12 BR BR0017010-0A patent/BR0017010A/pt not_active Application Discontinuation
- 2000-12-12 AU AU20899/01A patent/AU783078B2/en not_active Ceased
- 2000-12-12 KR KR1020027009515A patent/KR20020067701A/ko not_active Application Discontinuation
- 2000-12-12 DE DE60039194T patent/DE60039194D1/de not_active Expired - Lifetime
- 2000-12-12 HU HU0204101A patent/HUP0204101A3/hu unknown
- 2000-12-12 WO PCT/US2000/033656 patent/WO2001053273A1/en active Search and Examination
- 2000-12-12 AP APAP/P/2002/002603A patent/AP2002002603A0/en unknown
- 2000-12-12 OA OA1200200210A patent/OA12316A/en unknown
- 2000-12-12 EA EA200200661A patent/EA005585B1/ru not_active IP Right Cessation
- 2000-12-12 ES ES00984246T patent/ES2304992T3/es not_active Expired - Lifetime
- 2000-12-12 SK SK1057-2002A patent/SK10572002A3/sk unknown
- 2000-12-12 IL IL15039300A patent/IL150393A0/xx unknown
- 2000-12-12 GE GE4912A patent/GEP20053429B/en unknown
- 2000-12-12 JP JP2001553275A patent/JP4811978B2/ja not_active Expired - Fee Related
2001
- 2001-01-19 PA PA20018510101A patent/PA8510101A1/es unknown
- 2001-01-22 HN HN2001000009A patent/HN2001000009A/es unknown
- 2001-01-22 TN TNTNSN01011A patent/TNSN01011A1/en unknown
- 2001-01-22 UY UY26551A patent/UY26551A1/es not_active Application Discontinuation
- 2001-01-22 CO CO01004183A patent/CO5320600A1/es not_active Application Discontinuation
- 2001-01-22 SV SV2001000288A patent/SV2001000288A/es not_active Application Discontinuation
- 2001-01-22 PE PE2001000066A patent/PE20011060A1/es not_active Application Discontinuation
- 2001-01-23 AR ARP010100278A patent/AR030186A1/es unknown
2002
- 2002-06-27 IS IS6448A patent/IS6448A/is unknown
- 2002-07-19 CR CR6709A patent/CR6709A/es not_active Application Discontinuation
- 2002-07-22 MA MA26734A patent/MA26866A1/fr unknown
- 2002-07-23 NO NO20023516A patent/NO20023516D0/no not_active Application Discontinuation
- 2002-08-22 BG BG107023A patent/BG107023A/xx unknown
- 2002-08-23 HR HR20020696A patent/HRP20020696A2/hr not_active Application Discontinuation
2003
- 2003-09-11 HK HK03106519.6A patent/HK1054237A1/zh unknown
2006
- 2006-06-13 US US11/452,121 patent/US7582627B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
EP1255739A1 (en)	2002-11-13
US20060287308A1 (en)	2006-12-21
HN2001000009A (es)	2001-06-13
HK1054237A1 (zh)	2003-11-21
CN1425008A (zh)	2003-06-18
OA12316A (en)	2006-05-15
HRP20020696A2 (en)	2003-12-31
AU2089901A (en)	2001-07-31
BR0017010A (pt)	2002-11-05
EE200200412A (et)	2003-10-15
CO5320600A1 (es)	2003-09-30
GEP20053429B (en)	2005-01-25
UY26551A1 (es)	2001-04-30
ATE398110T1 (de)	2008-07-15
HUP0204101A3 (en)	2004-05-28
US20060183762A1 (en)	2006-08-17
DE60039194D1 (de)	2008-07-24
MXPA02005989A (es)	2002-10-23
AR030186A1 (es)	2003-08-13
BG107023A (en)	2003-04-30
AP2002002603A0 (en)	2002-09-30
CR6709A (es)	2003-11-25
HUP0204101A2 (hu)	2003-04-28
ES2304992T3 (es)	2008-11-01
AU783078B2 (en)	2005-09-22
PA8510101A1 (es)	2003-06-30
EA005585B1 (ru)	2005-04-28
US7582627B2 (en)	2009-09-01
SV2001000288A (es)	2001-11-30
MA26866A1 (fr)	2004-12-20
JP2003520277A (ja)	2003-07-02
IS6448A (is)	2002-06-27
YU55902A (sh)	2006-01-16
EP1255739B1 (en)	2008-06-11
US7094780B1 (en)	2006-08-22
JP4811978B2 (ja)	2011-11-09
NO20023516D0 (no)	2002-07-23
CA2393802C (en)	2011-04-19
IL150393A0 (en)	2002-12-01
SK10572002A3 (sk)	2003-10-07
PE20011060A1 (es)	2001-10-12
WO2001053273A1 (en)	2001-07-26
KR20020067701A (ko)	2002-08-23
TNSN01011A1 (en)	2005-11-10
CA2393802A1 (en)	2001-07-26
PL356837A1 (en)	2004-07-12
EA200200661A1 (ru)	2003-02-27

Publication	Publication Date	Title
NO20023516L (no)	2002-07-23	Antibakterielle 3-aminokinazolinon-2,4-dioner
MX242679B (es)	2006-12-14	Antranilamidas insecticidas.
DE60113450D1 (de)	2005-10-20	Antimikrobielle chinolone
NL1017075A1 (nl)	2001-07-11	Preparaat.
FI20000004A0 (fi)	2000-01-03	Flavonoidilääke...
MXPA03001148A (es)	2003-06-09	Antibioticos macrolidos.
NL1019181A1 (nl)	2002-04-18	Gestabiliseerd metalloceen-polypropeen.
NL1017973A1 (nl)	2001-11-13	Inrichting.
BR0102058B1 (pt)	2009-08-11	persiana.
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