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MY8700806A - Quinoline-3-carboxylic acid derivatives process for their manufacture pharmaceutical preparations containing them & their use - Google Patents

Quinoline-3-carboxylic acid derivatives process for their manufacture pharmaceutical preparations containing them & their use

Info

Publication number
MY8700806A
MY8700806A MY806/87A MY8700806A MY8700806A MY 8700806 A MY8700806 A MY 8700806A MY 806/87 A MY806/87 A MY 806/87A MY 8700806 A MY8700806 A MY 8700806A MY 8700806 A MY8700806 A MY 8700806A
Authority
MY
Malaysia
Prior art keywords
quinoline
carboxylic acid
acid derivatives
pharmaceutical preparations
preparations containing
Prior art date
Application number
MY806/87A
Other languages
English (en)
Inventor
Richard Goschke
Pier Giorgio Ferrini
Alfred Sallmann
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of MY8700806A publication Critical patent/MY8700806A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D265/00Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/041,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/121,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
    • C07D265/141,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D265/241,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in positions 2 and 4
    • C07D265/26Two oxygen atoms, e.g. isatoic anhydride
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32Oxygen atoms
    • C07D209/34Oxygen atoms in position 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32Oxygen atoms
    • C07D209/38Oxygen atoms in positions 2 and 3, e.g. isatin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
MY806/87A 1981-03-24 1987-12-30 Quinoline-3-carboxylic acid derivatives process for their manufacture pharmaceutical preparations containing them & their use MY8700806A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH198681 1981-03-24

Publications (1)

Publication Number Publication Date
MY8700806A true MY8700806A (en) 1987-12-31

Family

ID=4223231

Family Applications (1)

Application Number Title Priority Date Filing Date
MY806/87A MY8700806A (en) 1981-03-24 1987-12-30 Quinoline-3-carboxylic acid derivatives process for their manufacture pharmaceutical preparations containing them & their use

Country Status (22)

Country Link
US (1) US4476132A (hu)
EP (1) EP0062001B1 (hu)
JP (1) JPH066576B2 (hu)
AR (4) AR242189A1 (hu)
AT (1) ATE27451T1 (hu)
AU (1) AU560003B2 (hu)
CY (1) CY1412A (hu)
DE (1) DE3276432D1 (hu)
DK (1) DK159427C (hu)
ES (7) ES8400092A1 (hu)
FI (1) FI77853C (hu)
GB (1) GB2095668B (hu)
GR (1) GR78345B (hu)
HK (1) HK3988A (hu)
HU (1) HU192103B (hu)
IE (1) IE53158B1 (hu)
IL (1) IL65327A0 (hu)
MY (1) MY8700806A (hu)
NO (1) NO160074C (hu)
NZ (1) NZ200106A (hu)
PT (1) PT74634B (hu)
ZA (1) ZA821957B (hu)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58219166A (ja) * 1982-06-14 1983-12-20 Nippon Shinyaku Co Ltd 4−キノロン誘導体
JPS58225065A (ja) * 1982-06-21 1983-12-27 Nippon Shinyaku Co Ltd 2−キノロン誘導体
US4675432A (en) * 1986-08-29 1987-06-23 American Cyanamid Company Method for the preparation of anilinofumarate
US6034100A (en) * 1993-03-10 2000-03-07 Otsuka Pharmaceutical Co., Ltd. Method for inhibiting cytokine secretion
DE60134762D1 (de) * 2000-10-02 2008-08-21 Janssen Pharmaceutica Nv Metabotropische glutamatrezeptor-antagonisten
BR0308945A (pt) * 2002-03-29 2005-01-04 Janssen Pharmaceutica Nv Derivados radiomarcados de quinolina e quinolinona e uso dos mesmos como ligantes para receptores de glutamato metabotrópicos
EP2909189B8 (en) 2012-10-16 2017-04-19 Janssen Pharmaceutica NV Heteroaryl linked quinolinyl modulators of ror-gamma-t
BR112015008308A2 (pt) 2012-10-16 2017-12-05 Janssen Pharmaceutica Nv moduladores de quinolinila ligados por metileno do ror-gama-t
WO2014062667A1 (en) 2012-10-16 2014-04-24 Janssen Pharmaceutica Nv Phenyl linked quinolinyl modulators of ror-gamma-t
CA2926339A1 (en) 2013-10-15 2015-04-23 Janssen Pharmaceutica Nv Alkyl linked quinolinyl modulators of roryt
US9284308B2 (en) 2013-10-15 2016-03-15 Janssen Pharmaceutica Nv Methylene linked quinolinyl modulators of RORγt
US9403816B2 (en) 2013-10-15 2016-08-02 Janssen Pharmaceutica Nv Phenyl linked quinolinyl modulators of RORγt
US10555941B2 (en) 2013-10-15 2020-02-11 Janssen Pharmaceutica Nv Alkyl linked quinolinyl modulators of RORγt
US9328095B2 (en) 2013-10-15 2016-05-03 Janssen Pharmaceutica Nv Heteroaryl linked quinolinyl modulators of RORgammat
JP6608358B2 (ja) 2013-10-15 2019-11-20 ヤンセン ファーマシューティカ エヌ.ベー. RoRyTのキノリニルモジュレーター
US9221804B2 (en) 2013-10-15 2015-12-29 Janssen Pharmaceutica Nv Secondary alcohol quinolinyl modulators of RORγt

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB830832A (en) * 1957-02-15 1960-03-23 Ici Ltd New quinolones and therapeutic compositions containing them
GB1013224A (en) * 1962-06-21 1965-12-15 Ici Ltd Heterocyclic aminoethanols
CH538476A (de) * 1966-09-29 1973-06-30 Ciba Geigy Ag Verfahren zur Herstellung von heterocyclischen Carbonsäuren
US3496184A (en) * 1969-03-18 1970-02-17 Ciba Geigy Corp Cyclopropylmethoxy-3-quinoline carboxylic acids and esters
DE2103805C3 (de) * 1970-01-28 1980-03-20 Sumitomo Chemical Co., Ltd., Osaka (Japan) Verfahren zur Herstellung von N-substituierten 6,7-Methylendioxy-4chinolonen
GB1334705A (en) * 1970-06-19 1973-10-24 Ici Ltd Pharmaceutical compositions containing kynurenic acid derivatives
CA942748A (en) * 1970-09-18 1974-02-26 Venkatachala L. Narayanan 1-aziridinylcarbonyl substituted-3-quinolinecarboxylic acid compounds
US4190659A (en) * 1973-08-27 1980-02-26 Sandoz, Inc. Pharmaceutical preparation and use of 4-hydroxy-2-quinolinone-3-carboxylic acid esters
US4086349A (en) * 1975-07-30 1978-04-25 Mitsubishi Yuka Pharmaceutical Co., Ltd. Quinolopyran-4-one-2-carboxylic acid derivatives and salts thereof as novel compounds and as medicines for treatment of allergic asthma
JPS609511B2 (ja) * 1976-07-16 1985-03-11 大塚製薬株式会社 5−カルボスチリルメタノ−ル誘導体
JPS609713B2 (ja) * 1976-10-08 1985-03-12 大塚製薬株式会社 カルボスチリル誘導体
US4186201A (en) * 1977-02-07 1980-01-29 Riker Laboratories, Inc. Methods of using 8(tetrazol-5-ylcarbamoyl)isoquinoline compounds
US4187309A (en) * 1977-06-20 1980-02-05 Sandoz, Inc. 4-Hydroxy-2-quinolinone-3-carboxylic acids and salts thereof
US4119720A (en) * 1977-07-06 1978-10-10 Sandoz, Inc. Unsaturated esters of 4-hydroxy-2-quinolinone-3-carboxylic acids and salts thereof
DE2806879A1 (de) * 1978-02-17 1979-08-23 Sandoz Ag 4-hydroxy-2-chinolinon-3-carbonsaeure- esterderivate

Also Published As

Publication number Publication date
EP0062001A3 (en) 1983-01-26
AR242376A1 (es) 1993-03-31
GB2095668A (en) 1982-10-06
FI77853C (fi) 1989-05-10
AR242189A1 (es) 1993-03-31
GB2095668B (en) 1985-04-11
ES523339A0 (es) 1985-03-01
ES523337A0 (es) 1985-03-01
FI77853B (fi) 1989-01-31
JPH066576B2 (ja) 1994-01-26
ZA821957B (en) 1983-02-23
DK159427C (da) 1991-03-18
ES8503334A1 (es) 1985-02-16
US4476132A (en) 1984-10-09
IE820670L (en) 1982-09-24
NO160074B (no) 1988-11-28
ES523341A0 (es) 1985-02-16
ES8503662A1 (es) 1985-03-01
NZ200106A (en) 1985-07-31
EP0062001B1 (de) 1987-05-27
IE53158B1 (en) 1988-08-03
JPS57192366A (en) 1982-11-26
PT74634A (de) 1982-04-01
DE3276432D1 (en) 1987-07-02
AU8181982A (en) 1982-09-30
AR240739A1 (es) 1990-10-31
AR240044A1 (es) 1990-01-31
DK159427B (da) 1990-10-15
ES523338A0 (es) 1985-03-01
GR78345B (hu) 1984-09-26
IL65327A0 (en) 1982-05-31
ES8503661A1 (es) 1985-03-01
ATE27451T1 (de) 1987-06-15
ES510685A0 (es) 1983-10-16
PT74634B (de) 1984-11-26
FI820983L (fi) 1982-09-25
HK3988A (en) 1988-01-22
ES8400092A1 (es) 1983-10-16
DK130382A (da) 1982-09-25
ES8503664A1 (es) 1985-03-01
CY1412A (en) 1988-04-22
NO160074C (no) 1989-03-08
ES523342A0 (es) 1985-03-01
ES523340A0 (es) 1985-03-01
ES8503665A1 (es) 1985-03-01
AU560003B2 (en) 1987-03-26
ES8503663A1 (es) 1985-03-01
NO820959L (no) 1982-09-27
HU192103B (en) 1987-05-28
EP0062001A2 (de) 1982-10-06

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