HK3988A - Quinoline-3-carboxylic acid derivatives,process for their manufacture,pharmaceutical preparations containing them and their use - Google Patents
Quinoline-3-carboxylic acid derivatives,process for their manufacture,pharmaceutical preparations containing them and their useInfo
- Publication number
- HK3988A HK3988A HK39/88A HK3988A HK3988A HK 3988 A HK3988 A HK 3988A HK 39/88 A HK39/88 A HK 39/88A HK 3988 A HK3988 A HK 3988A HK 3988 A HK3988 A HK 3988A
- Authority
- HK
- Hong Kong
- Prior art keywords
- quinoline
- manufacture
- carboxylic acid
- acid derivatives
- pharmaceutical preparations
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
- C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
- C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D265/24—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in positions 2 and 4
- C07D265/26—Two oxygen atoms, e.g. isatoic anhydride
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/34—Oxygen atoms in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/38—Oxygen atoms in positions 2 and 3, e.g. isatin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
- C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Pulmonology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Quinoline Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH198681 | 1981-03-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK3988A true HK3988A (en) | 1988-01-22 |
Family
ID=4223231
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK39/88A HK3988A (en) | 1981-03-24 | 1988-01-14 | Quinoline-3-carboxylic acid derivatives,process for their manufacture,pharmaceutical preparations containing them and their use |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US4476132A (xx) |
| EP (1) | EP0062001B1 (xx) |
| JP (1) | JPH066576B2 (xx) |
| AR (4) | AR242189A1 (xx) |
| AT (1) | ATE27451T1 (xx) |
| AU (1) | AU560003B2 (xx) |
| CY (1) | CY1412A (xx) |
| DE (1) | DE3276432D1 (xx) |
| DK (1) | DK159427C (xx) |
| ES (7) | ES8400092A1 (xx) |
| FI (1) | FI77853C (xx) |
| GB (1) | GB2095668B (xx) |
| GR (1) | GR78345B (xx) |
| HK (1) | HK3988A (xx) |
| HU (1) | HU192103B (xx) |
| IE (1) | IE53158B1 (xx) |
| IL (1) | IL65327A0 (xx) |
| MY (1) | MY8700806A (xx) |
| NO (1) | NO160074C (xx) |
| NZ (1) | NZ200106A (xx) |
| PT (1) | PT74634B (xx) |
| ZA (1) | ZA821957B (xx) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS58219166A (ja) * | 1982-06-14 | 1983-12-20 | Nippon Shinyaku Co Ltd | ４−キノロン誘導体 |
| JPS58225065A (ja) * | 1982-06-21 | 1983-12-27 | Nippon Shinyaku Co Ltd | ２−キノロン誘導体 |
| US4675432A (en) * | 1986-08-29 | 1987-06-23 | American Cyanamid Company | Method for the preparation of anilinofumarate |
| US6034100A (en) * | 1993-03-10 | 2000-03-07 | Otsuka Pharmaceutical Co., Ltd. | Method for inhibiting cytokine secretion |
| DE60134762D1 (de) * | 2000-10-02 | 2008-08-21 | Janssen Pharmaceutica Nv | Metabotropische glutamatrezeptor-antagonisten |
| BR0308945A (pt) * | 2002-03-29 | 2005-01-04 | Janssen Pharmaceutica Nv | Derivados radiomarcados de quinolina e quinolinona e uso dos mesmos como ligantes para receptores de glutamato metabotrópicos |
| EP2909189B8 (en) | 2012-10-16 | 2017-04-19 | Janssen Pharmaceutica NV | Heteroaryl linked quinolinyl modulators of ror-gamma-t |
| BR112015008308A2 (pt) | 2012-10-16 | 2017-12-05 | Janssen Pharmaceutica Nv | moduladores de quinolinila ligados por metileno do ror-gama-t |
| WO2014062667A1 (en) | 2012-10-16 | 2014-04-24 | Janssen Pharmaceutica Nv | Phenyl linked quinolinyl modulators of ror-gamma-t |
| CA2926339A1 (en) | 2013-10-15 | 2015-04-23 | Janssen Pharmaceutica Nv | Alkyl linked quinolinyl modulators of roryt |
| US9284308B2 (en) | 2013-10-15 | 2016-03-15 | Janssen Pharmaceutica Nv | Methylene linked quinolinyl modulators of RORγt |
| US9403816B2 (en) | 2013-10-15 | 2016-08-02 | Janssen Pharmaceutica Nv | Phenyl linked quinolinyl modulators of RORγt |
| US10555941B2 (en) | 2013-10-15 | 2020-02-11 | Janssen Pharmaceutica Nv | Alkyl linked quinolinyl modulators of RORγt |
| US9328095B2 (en) | 2013-10-15 | 2016-05-03 | Janssen Pharmaceutica Nv | Heteroaryl linked quinolinyl modulators of RORgammat |
| JP6608358B2 (ja) | 2013-10-15 | 2019-11-20 | ヤンセン ファーマシューティカ エヌ．ベー． | ＲｏＲｙＴのキノリニルモジュレーター |
| US9221804B2 (en) | 2013-10-15 | 2015-12-29 | Janssen Pharmaceutica Nv | Secondary alcohol quinolinyl modulators of RORγt |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB830832A (en) * | 1957-02-15 | 1960-03-23 | Ici Ltd | New quinolones and therapeutic compositions containing them |
| GB1013224A (en) * | 1962-06-21 | 1965-12-15 | Ici Ltd | Heterocyclic aminoethanols |
| CH538476A (de) * | 1966-09-29 | 1973-06-30 | Ciba Geigy Ag | Verfahren zur Herstellung von heterocyclischen Carbonsäuren |
| US3496184A (en) * | 1969-03-18 | 1970-02-17 | Ciba Geigy Corp | Cyclopropylmethoxy-3-quinoline carboxylic acids and esters |
| DE2103805C3 (de) * | 1970-01-28 | 1980-03-20 | Sumitomo Chemical Co., Ltd., Osaka (Japan) | Verfahren zur Herstellung von N-substituierten 6,7-Methylendioxy-4chinolonen |
| GB1334705A (en) * | 1970-06-19 | 1973-10-24 | Ici Ltd | Pharmaceutical compositions containing kynurenic acid derivatives |
| CA942748A (en) * | 1970-09-18 | 1974-02-26 | Venkatachala L. Narayanan | 1-aziridinylcarbonyl substituted-3-quinolinecarboxylic acid compounds |
| US4190659A (en) * | 1973-08-27 | 1980-02-26 | Sandoz, Inc. | Pharmaceutical preparation and use of 4-hydroxy-2-quinolinone-3-carboxylic acid esters |
| US4086349A (en) * | 1975-07-30 | 1978-04-25 | Mitsubishi Yuka Pharmaceutical Co., Ltd. | Quinolopyran-4-one-2-carboxylic acid derivatives and salts thereof as novel compounds and as medicines for treatment of allergic asthma |
| JPS609511B2 (ja) * | 1976-07-16 | 1985-03-11 | 大塚製薬株式会社 | ５−カルボスチリルメタノ−ル誘導体 |
| JPS609713B2 (ja) * | 1976-10-08 | 1985-03-12 | 大塚製薬株式会社 | カルボスチリル誘導体 |
| US4186201A (en) * | 1977-02-07 | 1980-01-29 | Riker Laboratories, Inc. | Methods of using 8(tetrazol-5-ylcarbamoyl)isoquinoline compounds |
| US4187309A (en) * | 1977-06-20 | 1980-02-05 | Sandoz, Inc. | 4-Hydroxy-2-quinolinone-3-carboxylic acids and salts thereof |
| US4119720A (en) * | 1977-07-06 | 1978-10-10 | Sandoz, Inc. | Unsaturated esters of 4-hydroxy-2-quinolinone-3-carboxylic acids and salts thereof |
| DE2806879A1 (de) * | 1978-02-17 | 1979-08-23 | Sandoz Ag | 4-hydroxy-2-chinolinon-3-carbonsaeure- esterderivate |
-
1982
- 1982-03-18 AT AT82810126T patent/ATE27451T1/de not_active IP Right Cessation
- 1982-03-18 DE DE8282810126T patent/DE3276432D1/de not_active Expired
- 1982-03-18 EP EP82810126A patent/EP0062001B1/de not_active Expired
- 1982-03-19 US US06/360,016 patent/US4476132A/en not_active Expired - Lifetime
- 1982-03-22 FI FI820983A patent/FI77853C/fi not_active IP Right Cessation
- 1982-03-22 PT PT74634A patent/PT74634B/pt not_active IP Right Cessation
- 1982-03-22 GR GR67672A patent/GR78345B/el unknown
- 1982-03-23 CY CY141282A patent/CY1412A/xx unknown
- 1982-03-23 AU AU81819/82A patent/AU560003B2/en not_active Ceased
- 1982-03-23 DK DK130382A patent/DK159427C/da not_active IP Right Cessation
- 1982-03-23 NZ NZ200106A patent/NZ200106A/en unknown
- 1982-03-23 IL IL65327A patent/IL65327A0/xx not_active IP Right Cessation
- 1982-03-23 HU HU82881A patent/HU192103B/hu not_active IP Right Cessation
- 1982-03-23 IE IE670/82A patent/IE53158B1/en not_active IP Right Cessation
- 1982-03-23 NO NO820959A patent/NO160074C/no unknown
- 1982-03-23 GB GB8208394A patent/GB2095668B/en not_active Expired
- 1982-03-23 ZA ZA821957A patent/ZA821957B/xx unknown
- 1982-03-23 ES ES510685A patent/ES8400092A1/es not_active Expired
- 1982-03-24 JP JP57045754A patent/JPH066576B2/ja not_active Expired - Lifetime
- 1982-03-24 AR AR82288857A patent/AR242189A1/es active
-
1983
- 1983-06-16 ES ES523342A patent/ES8503665A1/es not_active Expired
- 1983-06-16 ES ES523337A patent/ES8503661A1/es not_active Expired
- 1983-06-16 ES ES523338A patent/ES523338A0/es active Granted
- 1983-06-16 ES ES523341A patent/ES523341A0/es active Granted
- 1983-06-16 ES ES523340A patent/ES523340A0/es active Granted
- 1983-06-16 ES ES523339A patent/ES8503663A1/es not_active Expired
- 1983-11-30 AR AR294972A patent/AR240044A1/es active
- 1983-11-30 AR AR29497383A patent/AR240739A1/es active
- 1983-11-30 AR AR83294975A patent/AR242376A1/es active
-
1987
- 1987-12-30 MY MY806/87A patent/MY8700806A/xx unknown
-
1988
- 1988-01-14 HK HK39/88A patent/HK3988A/xx unknown
Also Published As
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