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GR78345B - - Google Patents

Info

Publication number
GR78345B
GR78345B GR67672A GR820167672A GR78345B GR 78345 B GR78345 B GR 78345B GR 67672 A GR67672 A GR 67672A GR 820167672 A GR820167672 A GR 820167672A GR 78345 B GR78345 B GR 78345B
Authority
GR
Greece
Application number
GR67672A
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of GR78345B publication Critical patent/GR78345B/el

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D265/00Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/041,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/121,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
    • C07D265/141,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D265/241,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in positions 2 and 4
    • C07D265/26Two oxygen atoms, e.g. isatoic anhydride
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32Oxygen atoms
    • C07D209/34Oxygen atoms in position 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32Oxygen atoms
    • C07D209/38Oxygen atoms in positions 2 and 3, e.g. isatin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pulmonology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
GR67672A 1981-03-24 1982-03-22 GR78345B (el)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH198681 1981-03-24

Publications (1)

Publication Number Publication Date
GR78345B true GR78345B (el) 1984-09-26

Family

ID=4223231

Family Applications (1)

Application Number Title Priority Date Filing Date
GR67672A GR78345B (el) 1981-03-24 1982-03-22

Country Status (22)

Country Link
US (1) US4476132A (el)
EP (1) EP0062001B1 (el)
JP (1) JPH066576B2 (el)
AR (4) AR242189A1 (el)
AT (1) ATE27451T1 (el)
AU (1) AU560003B2 (el)
CY (1) CY1412A (el)
DE (1) DE3276432D1 (el)
DK (1) DK159427C (el)
ES (7) ES510685A0 (el)
FI (1) FI77853C (el)
GB (1) GB2095668B (el)
GR (1) GR78345B (el)
HK (1) HK3988A (el)
HU (1) HU192103B (el)
IE (1) IE53158B1 (el)
IL (1) IL65327A0 (el)
MY (1) MY8700806A (el)
NO (1) NO160074C (el)
NZ (1) NZ200106A (el)
PT (1) PT74634B (el)
ZA (1) ZA821957B (el)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58219166A (ja) * 1982-06-14 1983-12-20 Nippon Shinyaku Co Ltd 4−キノロン誘導体
JPS58225065A (ja) * 1982-06-21 1983-12-27 Nippon Shinyaku Co Ltd 2−キノロン誘導体
US4675432A (en) * 1986-08-29 1987-06-23 American Cyanamid Company Method for the preparation of anilinofumarate
US6034100A (en) * 1993-03-10 2000-03-07 Otsuka Pharmaceutical Co., Ltd. Method for inhibiting cytokine secretion
IL155163A0 (en) * 2000-10-02 2003-10-31 Janssen Pharmaceutica Nv Metabotropic glutamate receptor antagonists
CA2479109C (en) * 2002-03-29 2011-08-02 Janssen Pharmaceutica N.V. Radiolabelled quinoline and quinolinone derivatives and their use as metabotropic glutamate receptor ligands
ES2632269T3 (es) 2012-10-16 2017-09-12 Janssen Pharmaceutica Nv Moduladores de quinolinailo enlazados a metileno de ROR-gamma-t
CN104884448A (zh) 2012-10-16 2015-09-02 詹森药业有限公司 Rorγt的杂芳基连接的喹啉基调节剂
JP6251277B2 (ja) 2012-10-16 2017-12-20 ヤンセン ファーマシューティカ エヌ.ベー. ROR−ガンマ−tのフェニル結合キノリニルモジュレーター
US9328095B2 (en) 2013-10-15 2016-05-03 Janssen Pharmaceutica Nv Heteroaryl linked quinolinyl modulators of RORgammat
US9403816B2 (en) 2013-10-15 2016-08-02 Janssen Pharmaceutica Nv Phenyl linked quinolinyl modulators of RORγt
US9284308B2 (en) 2013-10-15 2016-03-15 Janssen Pharmaceutica Nv Methylene linked quinolinyl modulators of RORγt
CN105873439A (zh) 2013-10-15 2016-08-17 詹森药业有限公司 RORγt的烷基连接的喹啉基调节剂
US9221804B2 (en) 2013-10-15 2015-12-29 Janssen Pharmaceutica Nv Secondary alcohol quinolinyl modulators of RORγt
US10555941B2 (en) 2013-10-15 2020-02-11 Janssen Pharmaceutica Nv Alkyl linked quinolinyl modulators of RORγt
WO2015057626A1 (en) 2013-10-15 2015-04-23 Janssen Pharmaceutica Nv QUINOLINYL MODULATORS OF RORyT

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB830832A (en) * 1957-02-15 1960-03-23 Ici Ltd New quinolones and therapeutic compositions containing them
GB1013224A (en) * 1962-06-21 1965-12-15 Ici Ltd Heterocyclic aminoethanols
CH519304A (de) * 1966-09-29 1972-02-29 Ciba Geigy Ag Verwendung von heterocyclischen Carbonsäureverbindungen zur Aufzucht von Geflügel
US3496184A (en) * 1969-03-18 1970-02-17 Ciba Geigy Corp Cyclopropylmethoxy-3-quinoline carboxylic acids and esters
CA947301A (en) * 1970-01-28 1974-05-14 Sumitomo Chemical Company Process for the preparation of compound having antibacterial action
GB1334705A (en) * 1970-06-19 1973-10-24 Ici Ltd Pharmaceutical compositions containing kynurenic acid derivatives
CA942748A (en) * 1970-09-18 1974-02-26 Venkatachala L. Narayanan 1-aziridinylcarbonyl substituted-3-quinolinecarboxylic acid compounds
US4190659A (en) * 1973-08-27 1980-02-26 Sandoz, Inc. Pharmaceutical preparation and use of 4-hydroxy-2-quinolinone-3-carboxylic acid esters
US4086349A (en) * 1975-07-30 1978-04-25 Mitsubishi Yuka Pharmaceutical Co., Ltd. Quinolopyran-4-one-2-carboxylic acid derivatives and salts thereof as novel compounds and as medicines for treatment of allergic asthma
JPS609511B2 (ja) * 1976-07-16 1985-03-11 大塚製薬株式会社 5−カルボスチリルメタノ−ル誘導体
JPS609713B2 (ja) * 1976-10-08 1985-03-12 大塚製薬株式会社 カルボスチリル誘導体
US4186201A (en) * 1977-02-07 1980-01-29 Riker Laboratories, Inc. Methods of using 8(tetrazol-5-ylcarbamoyl)isoquinoline compounds
US4187309A (en) * 1977-06-20 1980-02-05 Sandoz, Inc. 4-Hydroxy-2-quinolinone-3-carboxylic acids and salts thereof
US4119720A (en) * 1977-07-06 1978-10-10 Sandoz, Inc. Unsaturated esters of 4-hydroxy-2-quinolinone-3-carboxylic acids and salts thereof
DE2806879A1 (de) * 1978-02-17 1979-08-23 Sandoz Ag 4-hydroxy-2-chinolinon-3-carbonsaeure- esterderivate

Also Published As

Publication number Publication date
FI77853B (fi) 1989-01-31
IL65327A0 (en) 1982-05-31
ES8503662A1 (es) 1985-03-01
AU8181982A (en) 1982-09-30
PT74634B (de) 1984-11-26
ES523337A0 (es) 1985-03-01
EP0062001A2 (de) 1982-10-06
ES8503661A1 (es) 1985-03-01
ES8400092A1 (es) 1983-10-16
DK159427B (da) 1990-10-15
ES8503663A1 (es) 1985-03-01
ES523338A0 (es) 1985-03-01
GB2095668B (en) 1985-04-11
EP0062001B1 (de) 1987-05-27
US4476132A (en) 1984-10-09
NO160074C (no) 1989-03-08
FI820983L (fi) 1982-09-25
HU192103B (en) 1987-05-28
ATE27451T1 (de) 1987-06-15
ES510685A0 (es) 1983-10-16
ES8503664A1 (es) 1985-03-01
CY1412A (en) 1988-04-22
ES523340A0 (es) 1985-03-01
ES523342A0 (es) 1985-03-01
FI77853C (fi) 1989-05-10
DK159427C (da) 1991-03-18
GB2095668A (en) 1982-10-06
PT74634A (de) 1982-04-01
HK3988A (en) 1988-01-22
AR242189A1 (es) 1993-03-31
AR240739A1 (es) 1990-10-31
ES523341A0 (es) 1985-02-16
ES523339A0 (es) 1985-03-01
MY8700806A (en) 1987-12-31
EP0062001A3 (en) 1983-01-26
IE820670L (en) 1982-09-24
JPH066576B2 (ja) 1994-01-26
NZ200106A (en) 1985-07-31
ZA821957B (en) 1983-02-23
AR240044A1 (es) 1990-01-31
IE53158B1 (en) 1988-08-03
AR242376A1 (es) 1993-03-31
NO160074B (no) 1988-11-28
ES8503665A1 (es) 1985-03-01
NO820959L (no) 1982-09-27
JPS57192366A (en) 1982-11-26
DE3276432D1 (en) 1987-07-02
DK130382A (da) 1982-09-25
ES8503334A1 (es) 1985-02-16
AU560003B2 (en) 1987-03-26

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