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MX2015011575A - Sistemas y metodos para la deteccion de celulas usando particulas manejadas de transduccion. - Google Patents

Sistemas y metodos para la deteccion de celulas usando particulas manejadas de transduccion.

Info

Publication number
MX2015011575A
MX2015011575A MX2015011575A MX2015011575A MX2015011575A MX 2015011575 A MX2015011575 A MX 2015011575A MX 2015011575 A MX2015011575 A MX 2015011575A MX 2015011575 A MX2015011575 A MX 2015011575A MX 2015011575 A MX2015011575 A MX 2015011575A
Authority
MX
Mexico
Prior art keywords
transduction particles
systems
methods
engineered
cells
Prior art date
Application number
MX2015011575A
Other languages
English (en)
Other versions
MX365093B (es
Inventor
Shaunak Roy
Diego Ariel Rey
Leonardo M Teixeira
Ryan C Griswold
Damian S Matthews
Kenneth G Olson
Rick V Stellmacher
Victor H Yee
Bruce J Richardson
Original Assignee
Geneweave Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Geneweave Biosciences Inc filed Critical Geneweave Biosciences Inc
Publication of MX2015011575A publication Critical patent/MX2015011575A/es
Publication of MX365093B publication Critical patent/MX365093B/es

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Abstract

En la presenten se describen sistemas y métodos para detectar y/o identificar células (o bacterias) diana usando partículas manejadas de transducción. En algunas modalidades, un método incluye mezclar una cantidad de partículas de transducción dentro de una muestra. Las partículas de transducción se asocian con una célula diana. Las partículas de transducción no son replicativas, y se manejan para incluir una molécula de ácido nucleico formulada para provocar que la célula diana produzca una serie de moléculas indicadoras. La muestra y las partículas de transducción se mantienen para expresar la serie de moléculas indicadoras cuando la célula diana está presente en la muestra. Se recibe una señal asociada con una cantidad de las moléculas indicadoras. En algunas modalidades, una magnitud de la señal es independiente de una cantidad de la partícula de transducción por arriba de una cantidad predeterminada.
MX2015011575A 2013-03-13 2014-03-11 Sistemas y metodos para la deteccion de celulas usando particulas manejadas de transduccion. MX365093B (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361779177P 2013-03-13 2013-03-13
US13/802,461 US9481903B2 (en) 2013-03-13 2013-03-13 Systems and methods for detection of cells using engineered transduction particles
PCT/US2014/023422 WO2014164768A1 (en) 2013-03-13 2014-03-11 Systems and methods for detection of cells using engineered transduction particles

Publications (2)

Publication Number Publication Date
MX2015011575A true MX2015011575A (es) 2016-05-16
MX365093B MX365093B (es) 2019-05-22

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MX2015011575A MX365093B (es) 2013-03-13 2014-03-11 Sistemas y metodos para la deteccion de celulas usando particulas manejadas de transduccion.

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US (6) US9481903B2 (es)
EP (3) EP3734279A1 (es)
JP (3) JP6524057B2 (es)
KR (3) KR102100186B1 (es)
CN (2) CN105209915B (es)
AU (3) AU2014249022C1 (es)
BR (1) BR112015022322A2 (es)
CA (1) CA2903771C (es)
ES (2) ES2703601T3 (es)
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