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MX2014003325A - Vacunoterapia. - Google Patents

Vacunoterapia.

Info

Publication number
MX2014003325A
MX2014003325A MX2014003325A MX2014003325A MX2014003325A MX 2014003325 A MX2014003325 A MX 2014003325A MX 2014003325 A MX2014003325 A MX 2014003325A MX 2014003325 A MX2014003325 A MX 2014003325A MX 2014003325 A MX2014003325 A MX 2014003325A
Authority
MX
Mexico
Prior art keywords
amyloid
vaccine therapy
young
syndrome
protein
Prior art date
Application number
MX2014003325A
Other languages
English (en)
Other versions
MX350928B (es
Inventor
Andreas Muhs
Andrea Pfeiter
Rime Madani
William Charles Mobley
Pavel Vasilyevich Belichenko
Original Assignee
Ac Immune Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ac Immune Sa filed Critical Ac Immune Sa
Publication of MX2014003325A publication Critical patent/MX2014003325A/es
Publication of MX350928B publication Critical patent/MX350928B/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0007Nervous system antigens; Prions
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10Peptides having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/385Haptens or antigens, bound to carriers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55555Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55572Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/60Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6018Lipids, e.g. in lipopeptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La presente invención proporciona medios para tratar, aliviar y prevenir una patología relacionada con amiloideos en sujetos desde jóvenes hasta edad intermedia con síndrome de Down (DS). En particular, la presente invención proporciona fragmentos de péptido antigénico derivados de una proteína amiloidea o una proteína similar a amiloidea para el uso en el tratamiento preventivo de una patología relacionada con amiloideos en sujetos desde jóvenes hasta edad intermedia, con síndrome de Down.
MX2014003325A 2011-09-23 2012-09-21 Vacunoterapia. MX350928B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
USPCT/US2011/052992 2011-09-23
PCT/US2012/056728 WO2013044147A1 (en) 2011-09-23 2012-09-21 Vaccine therapy

Publications (2)

Publication Number Publication Date
MX2014003325A true MX2014003325A (es) 2014-05-21
MX350928B MX350928B (es) 2017-09-26

Family

ID=47018510

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014003325A MX350928B (es) 2011-09-23 2012-09-21 Vacunoterapia.

Country Status (22)

Country Link
US (1) US20240270829A1 (es)
EP (1) EP2758071B1 (es)
JP (1) JP6110861B2 (es)
KR (3) KR102129220B1 (es)
CN (2) CN109847058A (es)
AU (1) AU2012312126B2 (es)
BR (1) BR112014006871A2 (es)
CA (1) CA2811188C (es)
DK (1) DK2758071T3 (es)
EA (1) EA032494B1 (es)
ES (1) ES2712951T3 (es)
HU (1) HUE041277T2 (es)
IL (1) IL231564A0 (es)
MX (1) MX350928B (es)
MY (1) MY169574A (es)
PL (1) PL2758071T3 (es)
PT (1) PT2758071T (es)
SG (1) SG11201400795UA (es)
SI (1) SI2758071T1 (es)
TR (1) TR201901846T4 (es)
WO (1) WO2013044147A1 (es)
ZA (1) ZA201402071B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20150646A1 (es) 2012-08-16 2015-05-21 Ipierian Inc Metodos de tratamiento de una tauopatia
US8980270B2 (en) 2013-01-18 2015-03-17 Ipierian, Inc. Methods of treating a tauopathy
NZ630610A (en) 2014-02-14 2019-05-31 Ipierian Inc Tau peptides, anti-tau antibodies, and methods of use thereof
CA3118692A1 (en) 2018-11-06 2020-05-14 Alsatech, Inc. Cell-based gene therapy for neurodegenerative diseases
TW202110425A (zh) 2019-05-21 2021-03-16 瑞士商Ac 免疫有限公司 抗Aβ疫苗治療
WO2024156912A1 (en) 2023-01-26 2024-08-02 Ac Immune Sa Anti-abeta vaccine therapy

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU9123998A (en) 1997-08-28 1999-03-16 Ajay North America Methods and compositions for protecting plants and crops
MXPA05006940A (es) 2002-12-24 2006-02-22 Neurochem Int Ltd Formulaciones terapeuticas para el tratamiento de enfermedades relacionadas con beta - amiloide.
NZ567324A (en) * 2003-02-01 2009-08-28 Wyeth Corp Active immunization to generate antibodies to soluble A-beta
US8663650B2 (en) 2003-02-21 2014-03-04 Ac Immune Sa Methods and compositions comprising supramolecular constructs
AR047062A1 (es) * 2003-12-17 2006-01-04 Wyeth Corp Conjugados portadores de peptidos inmunogenicos a beta y metodos para producirlos
KR20070040824A (ko) * 2004-07-30 2007-04-17 리나트 뉴로사이언스 코퍼레이션 아밀로이드-베타 펩티드에 대해 지시된 항체 및 이의 사용방법
CN101330923B (zh) * 2005-12-12 2015-01-07 Ac免疫有限公司 治疗性疫苗
WO2008156621A1 (en) * 2007-06-12 2008-12-24 Ac Immune S.A. Monoclonal anti beta amyloid antibody
WO2010106127A2 (en) * 2009-03-18 2010-09-23 Ac Immune S.A. Method for therapeutic use

Also Published As

Publication number Publication date
PT2758071T (pt) 2019-01-11
SG11201400795UA (en) 2014-10-30
EA201400376A1 (ru) 2014-09-30
SI2758071T1 (sl) 2019-01-31
KR20160099732A (ko) 2016-08-22
EA032494B1 (ru) 2019-06-28
CA2811188C (en) 2020-04-28
IL231564A0 (en) 2014-04-30
MY169574A (en) 2019-04-22
WO2013044147A1 (en) 2013-03-28
AU2012312126A1 (en) 2014-03-27
BR112014006871A2 (pt) 2017-04-04
NZ622653A (en) 2015-12-24
PL2758071T3 (pl) 2019-08-30
ES2712951T3 (es) 2019-05-16
KR102129220B1 (ko) 2020-07-02
TR201901846T4 (tr) 2019-03-21
EP2758071A1 (en) 2014-07-30
DK2758071T3 (en) 2019-02-18
CN104039346A (zh) 2014-09-10
CA2811188A1 (en) 2013-03-23
JP6110861B2 (ja) 2017-04-05
MX350928B (es) 2017-09-26
CN109847058A (zh) 2019-06-07
HUE041277T2 (hu) 2019-05-28
AU2012312126B2 (en) 2016-11-10
US20240270829A1 (en) 2024-08-15
ZA201402071B (en) 2017-08-30
KR20190035948A (ko) 2019-04-03
EP2758071B1 (en) 2018-11-28
KR20160005380A (ko) 2016-01-15
JP2014531455A (ja) 2014-11-27

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