MA26427A1 - Trihydrate de mesylate de 5-(2-(4-(1,2-benzisothiazole-3-yl)-1-piperazinyl)-ethyl)-6-chloro-1,3-dihydro-2h-indole-2-one, procede pour sa preparation et compositions pharmaceutiques le contenant - Google Patents

Trihydrate de mesylate de 5-(2-(4-(1,2-benzisothiazole-3-yl)-1-piperazinyl)-ethyl)-6-chloro-1,3-dihydro-2h-indole-2-one, procede pour sa preparation et compositions pharmaceutiques le contenant

Info

Publication number: MA26427A1
Authority: MA; Morocco
Prior art keywords: benzisothiazole; piperazinyl; indole; dihydro; chloro
Prior art date: 1996-05-07

Application number

MA24594A

Other languages

English (en)

Inventor

A Rose Carol

R Busch Frank

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-05-07

Filing date

1997-05-06

Publication date

2004-12-20

1997-05-06 Application filed by Pfizer filed Critical Pfizer

2004-12-20 Publication of MA26427A1 publication Critical patent/MA26427A1/fr

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Neurosurgery (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Pain & Pain Management (AREA)
Psychiatry (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

MA24594A 1996-05-07 1997-05-06 Trihydrate de mesylate de 5-(2-(4-(1,2-benzisothiazole-3-yl)-1-piperazinyl)-ethyl)-6-chloro-1,3-dihydro-2h-indole-2-one, procede pour sa preparation et compositions pharmaceutiques le contenant MA26427A1 (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US1653796P	1996-05-07	1996-05-07

Publications (1)

Publication Number	Publication Date
MA26427A1 true MA26427A1 (fr)	2004-12-20

Family

ID=21777622

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
MA24594A MA26427A1 (fr)	1996-05-07	1997-05-06	Trihydrate de mesylate de 5-(2-(4-(1,2-benzisothiazole-3-yl)-1-piperazinyl)-ethyl)-6-chloro-1,3-dihydro-2h-indole-2-one, procede pour sa preparation et compositions pharmaceutiques le contenant

Country Status (46)

Country	Link
US (1)	US6110918A (fr)
EP (1)	EP0904273B1 (fr)
JP (1)	JP3102896B2 (fr)
KR (1)	KR100333214B1 (fr)
CN (1)	CN1092658C (fr)
AP (1)	AP838A (fr)
AR (1)	AR007003A1 (fr)
AT (1)	ATE236902T1 (fr)
AU (1)	AU730856C (fr)
BG (1)	BG63601B1 (fr)
BR (1)	BR9708932A (fr)
CA (1)	CA2252895C (fr)
CO (1)	CO4940465A1 (fr)
CZ (1)	CZ289216B6 (fr)
DE (1)	DE69720719T2 (fr)
DK (1)	DK0904273T3 (fr)
DZ (1)	DZ2221A1 (fr)
EA (1)	EA001180B1 (fr)
EG (1)	EG24401A (fr)
ES (1)	ES2192264T3 (fr)
GT (1)	GT199700042A (fr)
HK (1)	HK1017893A1 (fr)
HN (1)	HN1997000040A (fr)
HR (1)	HRP970235B1 (fr)
HU (1)	HU229057B1 (fr)
ID (1)	ID17504A (fr)
IL (1)	IL126590A (fr)
IS (1)	IS2301B (fr)
MA (1)	MA26427A1 (fr)
ME (1)	ME00901B (fr)
MY (1)	MY128051A (fr)
NO (1)	NO312513B1 (fr)
NZ (2)	NZ332219A (fr)
OA (1)	OA10908A (fr)
PL (1)	PL188164B1 (fr)
PT (1)	PT904273E (fr)
SI (1)	SI0904273T1 (fr)
SK (1)	SK282674B6 (fr)
TN (1)	TNSN97073A1 (fr)
TR (1)	TR199802241T2 (fr)
TW (1)	TW427989B (fr)
UA (1)	UA47467C2 (fr)
UY (1)	UY24543A1 (fr)
WO (1)	WO1997042190A1 (fr)
YU (1)	YU49398B (fr)
ZA (1)	ZA973875B (fr)

Families Citing this family (39)

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HN1996000101A (es) *	1996-02-28	1997-06-26	Inc Pfizer	Terapia combinada para la osteoporosis
TW491847B (en)	1996-05-07	2002-06-21	Pfizer	Mesylate dihydrate salts of 5-(2-(4-(1,2-benzisothiazol-3-yl)-1-piperazinyl)-ethyl)-6-chloro-1,3-dihydro-2h-indol-2-one
UA57734C2 (uk)	1996-05-07	2003-07-15	Пфайзер Інк.	Комплекси включення арилгетероциклічних солей
IL127497A (en) *	1997-12-18	2002-07-25	Pfizer Prod Inc	Medicinal products containing piperazinyl-heterocyclic compounds for the treatment of psychiatric disorders
EP0985414B1 (fr) *	1998-05-26	2003-08-27	Pfizer Products Inc.	Médicament pour le traitement du glaucôme et de la rétinopathie ischémique
US20080113025A1 (en) *	1998-11-02	2008-05-15	Elan Pharma International Limited	Compositions comprising nanoparticulate naproxen and controlled release hydrocodone
AP2002002552A0 (en)	1999-12-23	2002-06-30	Pfizer Prod Inc	Pharmaceutical compositions providing enhanced drug concentrations.
EP1286672B1 (fr) *	2000-06-02	2006-10-25	Pfizer Products Inc.	S-methyl-dihydro-ziprasidone pour traiter des troubles oculaires.
AR032641A1 (es) *	2001-01-29	2003-11-19	Otsuka Pharma Co Ltd	Agonista de subtipo de receptor 5-ht 1a.
US7053092B2 (en)	2001-01-29	2006-05-30	Otsuka Pharmaceutical Co., Ltd.	5-HT1a receptor subtype agonist
US8703772B2 (en)	2001-09-25	2014-04-22	Otsuka Pharmaceutical Co., Ltd.	Low hygroscopic aripiprazole drug substance and processes for the preparation thereof
AR033485A1 (es)	2001-09-25	2003-12-26	Otsuka Pharma Co Ltd	Sustancia medicinal de aripiprazol de baja higroscopicidad y proceso para la preparacion de la misma
US20040048876A1 (en) *	2002-02-20	2004-03-11	Pfizer Inc.	Ziprasidone composition and synthetic controls
UY27668A1 (es) *	2002-02-20	2003-10-31	Pfizer Prod Inc	Composición de ziprasidona y controles sintéticos
WO2004050655A1 (fr) *	2002-12-04	2004-06-17	Dr. Reddy's Laboratories Limited	Formes polymorphes de ziprasidone et son chlorhydrate
US7488729B2 (en)	2002-12-04	2009-02-10	Dr. Reddy's Laboratories Limited	Polymorphic forms of ziprasidone and its hydrochloride salt and process for preparation thereof
EP1626722A1 (fr) *	2003-05-16	2006-02-22	Pfizer Products Inc.	Procede pour ameliorer les fonctions cognitives en administrant du ziprasidone
EP1633360A1 (fr) *	2003-05-16	2006-03-15	Pfizer Products Incorporated	Traitement de troubles psychotiques et depressifs
BRPI0410419A (pt) *	2003-05-16	2006-05-30	Pfizer Prod Inc	tratamento para a ansiedade com ziprasidona
EP1546146A1 (fr) *	2003-06-03	2005-06-29	Teva Pharmaceutical Industries Limited	Formes polymorphes de ziprasidone chlorhydrate et procedes pour leur elaboration
MXPA06002455A (es) *	2003-09-02	2006-08-31	Pfizer Prod Inc	Formas de dosificacion de liberacion sostenida de ziprasidona.
WO2005040160A2 (fr) *	2003-10-24	2005-05-06	Teva Pharmaceutical Industries Ltd.	Procedes de preparation de ziprasidone
JP2007514001A (ja) *	2003-12-18	2007-05-31	テバファーマシューティカルインダストリーズリミティド	ジプラシドン塩基の多形形態ｂ２
CA2552126A1 (fr) *	2003-12-31	2005-07-21	Actavis Group Hf	Formulations de ziprasidone
PT1720867E (pt) *	2004-02-27	2010-01-28	Ranbaxy Lab Ltd	Processo para a preparação de ziprasidona
US9044503B2 (en) *	2004-08-27	2015-06-02	University Of Kentucky Research Foundation	Amyloid peptide inactivating enzyme to treat alzheimer's disease peripherally
ES2250001B1 (es) *	2004-09-29	2007-06-01	Medichem, S.A.	Proceso para la purificacion de ziprasidona.
US7777037B2 (en) *	2004-10-27	2010-08-17	Dr. Reddy's Laboratories Limited	Ziprasidone process
EA200701065A1 (ru) *	2004-11-16	2007-12-28	Элан Фарма Интернэшнл Лтд.	Инъецируемые составы, содержащие нанодисперсный оланзапин
EP1863806A1 (fr) *	2005-02-11	2007-12-12	Teva Pharmaceutical Industries Ltd	Ziprasidone mesylate amorphe
EP1855651A4 (fr) *	2005-03-03	2011-06-15	Elan Pharma Int Ltd	Compositions nanoparticulaires de derives d'amide heterocyclique
ITMI20050346A1 (it)	2005-03-07	2006-09-08	Dipharma Spa	Forma solida di ziprasidone cloridrato
US20060270685A1 (en) *	2005-03-14	2006-11-30	Judith Aronhime	Anhydrous ziprasidone mesylate and a process for its preparation
EP1858891A2 (fr) *	2005-03-14	2007-11-28	Teva Pharmaceutical Industries Ltd.	Formes cristallines de mesylate de ziprasidone
CN101677568A (zh) *	2007-05-18	2010-03-24	赛多斯有限责任公司	齐拉西酮制剂
KR100948126B1 (ko) *	2007-12-10	2010-03-18	씨제이제일제당 (주)	결정형의 지프라시돈 술폰산염, 그 제조방법, 및 그것를포함하는 약제학적 조성물
CN102234273B (zh) *	2010-04-21	2015-08-05	上海医药工业研究院	甲磺酸齐拉西酮半水合物及其制备方法
SI23610A (sl)	2011-01-13	2012-07-31	Diagen@d@o@o	Nove adicijske soli ziprasidona postopek za njihovo pripravo in njihova uporaba v terapiji
JP6440625B2 (ja)	2012-11-14	2018-12-19	ザ・ジョンズ・ホプキンス・ユニバーシティー	精神分裂病を処置するための方法および組成物

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MX173362B (es) *	1987-03-02	1994-02-23	Pfizer	Compuestos de piperazinil heterociclicos y procedimiento para su preparacion
US5312925A (en) *	1992-09-01	1994-05-17	Pfizer Inc.	Monohydrate of 5-(2-(4-(1,2-benzisothiazol-3-yl)-1-piperazinyl)-ethyl)-6-chloro-1,3-dihydro-2H-indol-2-one-hydrochloride
US5206366A (en) *	1992-08-26	1993-04-27	Pfizer Inc.	Process for preparing aryl piperazinyl-heterocyclic compounds
US5359068A (en) *	1993-06-28	1994-10-25	Pfizer Inc.	Processes and intermediates for the preparation of 5-[2-(4-(benzoisothiazol-3-yl)-piperazin-1-yl)ethyl]-6-chloro-1,3-dihydro-indol-2-one

1997
- 1997-03-26 HU HU9902808A patent/HU229057B1/hu unknown
- 1997-03-26 CZ CZ19983494A patent/CZ289216B6/cs not_active IP Right Cessation
- 1997-03-26 PL PL97329880A patent/PL188164B1/pl unknown
- 1997-03-26 JP JP09539668A patent/JP3102896B2/ja not_active Expired - Lifetime
- 1997-03-26 IL IL12659097A patent/IL126590A/en not_active IP Right Cessation
- 1997-03-26 AT AT97907237T patent/ATE236902T1/de active
- 1997-03-26 WO PCT/IB1997/000306 patent/WO1997042190A1/fr active IP Right Grant
- 1997-03-26 CA CA002252895A patent/CA2252895C/fr not_active Expired - Lifetime
- 1997-03-26 UA UA98105559A patent/UA47467C2/uk unknown
- 1997-03-26 CN CN97194243A patent/CN1092658C/zh not_active Expired - Lifetime
- 1997-03-26 PT PT97907237T patent/PT904273E/pt unknown
- 1997-03-26 ES ES97907237T patent/ES2192264T3/es not_active Expired - Lifetime
- 1997-03-26 SI SI9730526T patent/SI0904273T1/xx unknown
- 1997-03-26 BR BR9708932A patent/BR9708932A/pt not_active IP Right Cessation
- 1997-03-26 NZ NZ332219A patent/NZ332219A/en not_active IP Right Cessation
- 1997-03-26 SK SK1505-98A patent/SK282674B6/sk not_active IP Right Cessation
- 1997-03-26 EP EP97907237A patent/EP0904273B1/fr not_active Expired - Lifetime
- 1997-03-26 KR KR1019980708958A patent/KR100333214B1/ko not_active IP Right Cessation
- 1997-03-26 DK DK97907237T patent/DK0904273T3/da active
- 1997-03-26 TR TR1998/02241T patent/TR199802241T2/xx unknown
- 1997-03-26 DE DE69720719T patent/DE69720719T2/de not_active Expired - Lifetime
- 1997-03-26 AU AU19368/97A patent/AU730856C/en not_active Expired
- 1997-03-26 US US09/180,456 patent/US6110918A/en not_active Expired - Lifetime
- 1997-03-26 NZ NZ508303A patent/NZ508303A/en not_active IP Right Cessation
- 1997-03-26 EA EA199800909A patent/EA001180B1/ru not_active IP Right Cessation
- 1997-04-01 TW TW086104175A patent/TW427989B/zh not_active IP Right Cessation
- 1997-04-02 HN HN1997000040A patent/HN1997000040A/es unknown
- 1997-04-10 GT GT199700042A patent/GT199700042A/es unknown
- 1997-04-28 CO CO97022512A patent/CO4940465A1/es unknown
- 1997-04-30 AP APAP/P/1997/000978A patent/AP838A/en active
- 1997-05-04 EG EG37797A patent/EG24401A/xx active
- 1997-05-05 ID IDP971490A patent/ID17504A/id unknown
- 1997-05-05 AR ARP970101855A patent/AR007003A1/es unknown
- 1997-05-06 ZA ZA973875A patent/ZA973875B/xx unknown
- 1997-05-06 TN TNTNSN97073A patent/TNSN97073A1/fr unknown
- 1997-05-06 YU YU17397A patent/YU49398B/sh unknown
- 1997-05-06 UY UY24543A patent/UY24543A1/es not_active IP Right Cessation
- 1997-05-06 ME MEP-1997-173A patent/ME00901B/me unknown
- 1997-05-06 DZ DZ970068A patent/DZ2221A1/fr active
- 1997-05-06 MY MYPI97001988A patent/MY128051A/en unknown
- 1997-05-06 MA MA24594A patent/MA26427A1/fr unknown
- 1997-05-07 HR HR970235A patent/HRP970235B1/xx not_active IP Right Cessation
1998
- 1998-10-23 IS IS4878A patent/IS2301B/is unknown
- 1998-10-30 OA OA9800205A patent/OA10908A/fr unknown
- 1998-11-03 BG BG102893A patent/BG63601B1/bg unknown
- 1998-11-06 NO NO19985193A patent/NO312513B1/no not_active IP Right Cessation
1999
- 1999-07-12 HK HK99102956A patent/HK1017893A1/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
AR007003A1 (es)	1999-10-13
WO1997042190A1 (fr)	1997-11-13
JP3102896B2 (ja)	2000-10-23
YU17397A (sh)	2000-10-30
UA47467C2 (uk)	2002-07-15
KR20000010822A (ko)	2000-02-25
YU49398B (sh)	2005-11-28
HRP970235B1 (en)	2002-08-31
CA2252895C (fr)	2002-08-20
KR100333214B1 (ko)	2002-06-20
HUP9902808A2 (hu)	2000-03-28
AU1936897A (en)	1997-11-26
EP0904273B1 (fr)	2003-04-09
BG63601B1 (bg)	2002-06-28
NO985193D0 (no)	1998-11-06
IS2301B (is)	2007-10-15
NZ508303A (en)	2001-07-27
HN1997000040A (es)	1997-06-05
JPH11509865A (ja)	1999-08-31
PL188164B1 (pl)	2004-12-31
UY24543A1 (es)	2000-09-29
CN1092658C (zh)	2002-10-16
ES2192264T3 (es)	2003-10-01
IL126590A0 (en)	1999-08-17
SI0904273T1 (en)	2003-08-31
US6110918A (en)	2000-08-29
EA199800909A1 (ru)	1999-04-29
CA2252895A1 (fr)	1997-11-13
ME00901B (me)	2005-11-28
PT904273E (pt)	2003-06-30
AP9700978A0 (en)	1997-07-31
HRP970235A2 (en)	1998-06-30
NO312513B1 (no)	2002-05-21
HK1017893A1 (en)	1999-12-03
AP838A (en)	2000-05-03
DZ2221A1 (fr)	2002-12-03
AU730856B2 (en)	2001-03-15
AU730856C (en)	2001-11-15
EA001180B1 (ru)	2000-10-30
ZA973875B (en)	1998-11-06
GT199700042A (es)	1998-10-02
ID17504A (id)	1998-01-08
SK282674B6 (sk)	2002-11-06
DE69720719T2 (de)	2003-11-06
BR9708932A (pt)	1999-08-03
CZ289216B6 (cs)	2001-12-12
DK0904273T3 (da)	2003-07-07
EG24401A (en)	2009-04-29
OA10908A (en)	2001-10-26
PL329880A1 (en)	1999-04-12
CO4940465A1 (es)	2000-07-24
ATE236902T1 (de)	2003-04-15
TNSN97073A1 (fr)	2005-03-15
TW427989B (en)	2001-04-01
EP0904273A1 (fr)	1999-03-31
CZ349498A3 (cs)	1999-09-15
TR199802241T2 (fr)	1999-02-22
IS4878A (is)	1998-10-23
IL126590A (en)	2001-11-25
NO985193L (no)	1998-11-06
BG102893A (en)	1999-09-30
NZ332219A (en)	2005-02-25
SK150598A3 (en)	2000-03-13
MY128051A (en)	2007-01-31
HUP9902808A3 (en)	2000-04-28
HU229057B1 (en)	2013-07-29
CN1216990A (zh)	1999-05-19
DE69720719D1 (de)	2003-05-15

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