DZ2221A1 - Trihydrate de mésylate de 5-(2-(4-(1,2-benzisothiazole-3-yi)-1-pipérazinyl)-éthyl)-6-chloro-1,3-dihydro-2h-indole-2-one, procédé pour sa préparation et compositions pharmaceutiques le contenant. - Google Patents

Trihydrate de mésylate de 5-(2-(4-(1,2-benzisothiazole-3-yi)-1-pipérazinyl)-éthyl)-6-chloro-1,3-dihydro-2h-indole-2-one, procédé pour sa préparation et compositions pharmaceutiques le contenant.

Info

Publication number: DZ2221A1
Authority: DZ; Algeria
Prior art keywords: benzisothiazole; piperazinyl; indole; dihydro; chloro
Prior art date: 1996-05-07

Application number

DZ970068A

Other languages

English (en)

Inventor

Frank Robert Busch

Carol Anne Rose

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-05-07

Filing date

1997-05-06

Publication date

2002-12-03

1997-05-06 Application filed by Pfizer filed Critical Pfizer

2002-12-03 Application granted granted Critical

2002-12-03 Publication of DZ2221A1 publication Critical patent/DZ2221A1/fr

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Neurosurgery (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

DZ970068A 1996-05-07 1997-05-06 Trihydrate de mésylate de 5-(2-(4-(1,2-benzisothiazole-3-yi)-1-pipérazinyl)-éthyl)-6-chloro-1,3-dihydro-2h-indole-2-one, procédé pour sa préparation et compositions pharmaceutiques le contenant. DZ2221A1 (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US1653796P	1996-05-07	1996-05-07

Publications (1)

Publication Number	Publication Date
DZ2221A1 true DZ2221A1 (fr)	2002-12-03

Family

ID=21777622

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DZ970068A DZ2221A1 (fr)	1996-05-07	1997-05-06	Trihydrate de mésylate de 5-(2-(4-(1,2-benzisothiazole-3-yi)-1-pipérazinyl)-éthyl)-6-chloro-1,3-dihydro-2h-indole-2-one, procédé pour sa préparation et compositions pharmaceutiques le contenant.

Country Status (46)

Country	Link
US (1)	US6110918A (fr)
EP (1)	EP0904273B1 (fr)
JP (1)	JP3102896B2 (fr)
KR (1)	KR100333214B1 (fr)
CN (1)	CN1092658C (fr)
AP (1)	AP838A (fr)
AR (1)	AR007003A1 (fr)
AT (1)	ATE236902T1 (fr)
AU (1)	AU730856C (fr)
BG (1)	BG63601B1 (fr)
BR (1)	BR9708932A (fr)
CA (1)	CA2252895C (fr)
CO (1)	CO4940465A1 (fr)
CZ (1)	CZ289216B6 (fr)
DE (1)	DE69720719T2 (fr)
DK (1)	DK0904273T3 (fr)
DZ (1)	DZ2221A1 (fr)
EA (1)	EA001180B1 (fr)
EG (1)	EG24401A (fr)
ES (1)	ES2192264T3 (fr)
GT (1)	GT199700042A (fr)
HK (1)	HK1017893A1 (fr)
HN (1)	HN1997000040A (fr)
HR (1)	HRP970235B1 (fr)
HU (1)	HU229057B1 (fr)
ID (1)	ID17504A (fr)
IL (1)	IL126590A (fr)
IS (1)	IS2301B (fr)
MA (1)	MA26427A1 (fr)
ME (1)	ME00901B (fr)
MY (1)	MY128051A (fr)
NO (1)	NO312513B1 (fr)
NZ (2)	NZ508303A (fr)
OA (1)	OA10908A (fr)
PL (1)	PL188164B1 (fr)
PT (1)	PT904273E (fr)
SI (1)	SI0904273T1 (fr)
SK (1)	SK282674B6 (fr)
TN (1)	TNSN97073A1 (fr)
TR (1)	TR199802241T2 (fr)
TW (1)	TW427989B (fr)
UA (1)	UA47467C2 (fr)
UY (1)	UY24543A1 (fr)
WO (1)	WO1997042190A1 (fr)
YU (1)	YU49398B (fr)
ZA (1)	ZA973875B (fr)

Families Citing this family (39)

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HN1996000101A (es) *	1996-02-28	1997-06-26	Inc Pfizer	Terapia combinada para la osteoporosis
TW491847B (en)	1996-05-07	2002-06-21	Pfizer	Mesylate dihydrate salts of 5-(2-(4-(1,2-benzisothiazol-3-yl)-1-piperazinyl)-ethyl)-6-chloro-1,3-dihydro-2h-indol-2-one
UA57734C2 (uk)	1996-05-07	2003-07-15	Пфайзер Інк.	Комплекси включення арилгетероциклічних солей
IL127497A (en) *	1997-12-18	2002-07-25	Pfizer Prod Inc	Medicinal products containing piperazinyl-heterocyclic compounds for the treatment of psychiatric disorders
DK0985414T3 (da) *	1998-05-26	2003-12-29	Pfizer Prod Inc	Lægemiddel til behandling af glaukome og iskæmisk retinopati
US20080113025A1 (en) *	1998-11-02	2008-05-15	Elan Pharma International Limited	Compositions comprising nanoparticulate naproxen and controlled release hydrocodone
TR200201617T2 (tr)	1999-12-23	2002-10-21	Pfizer Products Inc.	Kuvvetlendirilmiş ilaç konsantrasyonları sağlayan farmasötik kompozisyonlar
SI1468686T1 (sl) *	2000-06-02	2007-04-30	Pfizer Prod Inc	S-metil-dihidro-ziprazidon za zdravljenje psihiatricnih motenj
US7053092B2 (en)	2001-01-29	2006-05-30	Otsuka Pharmaceutical Co., Ltd.	5-HT1a receptor subtype agonist
AR032641A1 (es) *	2001-01-29	2003-11-19	Otsuka Pharma Co Ltd	Agonista de subtipo de receptor 5-ht 1a.
US8703772B2 (en)	2001-09-25	2014-04-22	Otsuka Pharmaceutical Co., Ltd.	Low hygroscopic aripiprazole drug substance and processes for the preparation thereof
AR033485A1 (es)	2001-09-25	2003-12-26	Otsuka Pharma Co Ltd	Sustancia medicinal de aripiprazol de baja higroscopicidad y proceso para la preparacion de la misma
UY27668A1 (es) *	2002-02-20	2003-10-31	Pfizer Prod Inc	Composición de ziprasidona y controles sintéticos
US20040048876A1 (en) *	2002-02-20	2004-03-11	Pfizer Inc.	Ziprasidone composition and synthetic controls
WO2004050655A1 (fr) *	2002-12-04	2004-06-17	Dr. Reddy's Laboratories Limited	Formes polymorphes de ziprasidone et son chlorhydrate
US7488729B2 (en)	2002-12-04	2009-02-10	Dr. Reddy's Laboratories Limited	Polymorphic forms of ziprasidone and its hydrochloride salt and process for preparation thereof
EP1626722A1 (fr) *	2003-05-16	2006-02-22	Pfizer Products Inc.	Procede pour ameliorer les fonctions cognitives en administrant du ziprasidone
WO2004100955A1 (fr) *	2003-05-16	2004-11-25	Pfizer Products Inc.	Traitements de l'angoisse avec la ziprasidone
EP1633360A1 (fr) *	2003-05-16	2006-03-15	Pfizer Products Incorporated	Traitement de troubles psychotiques et depressifs
CA2528100A1 (fr) *	2003-06-03	2005-04-21	Teva Pharmaceutical Industries Ltd	Formes polymorphes de ziprasidone chlorhydrate et procedes pour leur elaboration
KR20090080143A (ko) *	2003-09-02	2009-07-23	화이자 프로덕츠 인크.	지프라시돈의 지속 방출형 투여 형태
WO2005040160A2 (fr) *	2003-10-24	2005-05-06	Teva Pharmaceutical Industries Ltd.	Procedes de preparation de ziprasidone
EP1592688A2 (fr)	2003-12-18	2005-11-09	Teva Pharmaceutical Industries Ltd.	Forme polymorphe b2 de base de ziprasidone
CA2552126A1 (fr) *	2003-12-31	2005-07-21	Actavis Group Hf	Formulations de ziprasidone
WO2005085240A2 (fr) *	2004-02-27	2005-09-15	Ranbaxy Laboratories Limited	Procede de preparation de ziprasidone
WO2006026426A2 (fr) *	2004-08-27	2006-03-09	University Of Kentucky Research Foundation	Enzyme d'inactivation de peptide amyloide pour traiter la maladie d'alzheimer de façon peripherique
ES2250001B1 (es) *	2004-09-29	2007-06-01	Medichem, S.A.	Proceso para la purificacion de ziprasidona.
US7777037B2 (en) *	2004-10-27	2010-08-17	Dr. Reddy's Laboratories Limited	Ziprasidone process
JP5324098B2 (ja) *	2004-11-16	2013-10-23	アルケルメスファーマアイルランドリミテッド	注射可能なナノ粒子のオランザピン製剤
CA2593497A1 (fr) *	2005-02-11	2006-08-17	Judith Aronhime	Ziprasidone mesylate amorphe
CA2598288A1 (fr) *	2005-03-03	2006-09-14	Elan Pharma International Limited	Compositions nanoparticulaires de derives d'amide heterocyclique
ITMI20050346A1 (it)	2005-03-07	2006-09-08	Dipharma Spa	Forma solida di ziprasidone cloridrato
CA2599391A1 (fr) *	2005-03-14	2006-09-21	Teva Pharmaceutical Industries Ltd.	Formes cristallines de mesylate de ziprasidone
WO2006099452A1 (fr) *	2005-03-14	2006-09-21	Teva Pharmaceutical Industries Ltd.	Mesylate de ziprasidone anhydre et son procede de preparation
MX2009011681A (es) *	2007-05-18	2009-11-10	Scidose Llc	Formulaciones de ziprasidona.
KR100948126B1 (ko) *	2007-12-10	2010-03-18	씨제이제일제당 (주)	결정형의 지프라시돈 술폰산염, 그 제조방법, 및 그것를포함하는 약제학적 조성물
CN102234273B (zh) *	2010-04-21	2015-08-05	上海医药工业研究院	甲磺酸齐拉西酮半水合物及其制备方法
SI23610A (sl)	2011-01-13	2012-07-31	Diagen@d@o@o	Nove adicijske soli ziprasidona postopek za njihovo pripravo in njihova uporaba v terapiji
JP6440625B2 (ja)	2012-11-14	2018-12-19	ザ・ジョンズ・ホプキンス・ユニバーシティー	精神分裂病を処置するための方法および組成物

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MX173362B (es) *	1987-03-02	1994-02-23	Pfizer	Compuestos de piperazinil heterociclicos y procedimiento para su preparacion
US5312925A (en) *	1992-09-01	1994-05-17	Pfizer Inc.	Monohydrate of 5-(2-(4-(1,2-benzisothiazol-3-yl)-1-piperazinyl)-ethyl)-6-chloro-1,3-dihydro-2H-indol-2-one-hydrochloride
US5206366A (en) *	1992-08-26	1993-04-27	Pfizer Inc.	Process for preparing aryl piperazinyl-heterocyclic compounds
US5359068A (en) *	1993-06-28	1994-10-25	Pfizer Inc.	Processes and intermediates for the preparation of 5-[2-(4-(benzoisothiazol-3-yl)-piperazin-1-yl)ethyl]-6-chloro-1,3-dihydro-indol-2-one

1997
- 1997-03-26 EP EP97907237A patent/EP0904273B1/fr not_active Expired - Lifetime
- 1997-03-26 CN CN97194243A patent/CN1092658C/zh not_active Expired - Lifetime
- 1997-03-26 DE DE69720719T patent/DE69720719T2/de not_active Expired - Lifetime
- 1997-03-26 CZ CZ19983494A patent/CZ289216B6/cs not_active IP Right Cessation
- 1997-03-26 SK SK1505-98A patent/SK282674B6/sk not_active IP Right Cessation
- 1997-03-26 UA UA98105559A patent/UA47467C2/uk unknown
- 1997-03-26 AT AT97907237T patent/ATE236902T1/de active
- 1997-03-26 HU HU9902808A patent/HU229057B1/hu unknown
- 1997-03-26 EA EA199800909A patent/EA001180B1/ru not_active IP Right Cessation
- 1997-03-26 IL IL12659097A patent/IL126590A/en not_active IP Right Cessation
- 1997-03-26 US US09/180,456 patent/US6110918A/en not_active Expired - Lifetime
- 1997-03-26 NZ NZ508303A patent/NZ508303A/en not_active IP Right Cessation
- 1997-03-26 JP JP09539668A patent/JP3102896B2/ja not_active Expired - Lifetime
- 1997-03-26 WO PCT/IB1997/000306 patent/WO1997042190A1/fr active IP Right Grant
- 1997-03-26 PT PT97907237T patent/PT904273E/pt unknown
- 1997-03-26 SI SI9730526T patent/SI0904273T1/xx unknown
- 1997-03-26 NZ NZ332219A patent/NZ332219A/en not_active IP Right Cessation
- 1997-03-26 BR BR9708932A patent/BR9708932A/pt not_active IP Right Cessation
- 1997-03-26 DK DK97907237T patent/DK0904273T3/da active
- 1997-03-26 ES ES97907237T patent/ES2192264T3/es not_active Expired - Lifetime
- 1997-03-26 CA CA002252895A patent/CA2252895C/fr not_active Expired - Lifetime
- 1997-03-26 PL PL97329880A patent/PL188164B1/pl unknown
- 1997-03-26 AU AU19368/97A patent/AU730856C/en not_active Expired
- 1997-03-26 KR KR1019980708958A patent/KR100333214B1/ko not_active IP Right Cessation
- 1997-03-26 TR TR1998/02241T patent/TR199802241T2/xx unknown
- 1997-04-01 TW TW086104175A patent/TW427989B/zh not_active IP Right Cessation
- 1997-04-02 HN HN1997000040A patent/HN1997000040A/es unknown
- 1997-04-10 GT GT199700042A patent/GT199700042A/es unknown
- 1997-04-28 CO CO97022512A patent/CO4940465A1/es unknown
- 1997-04-30 AP APAP/P/1997/000978A patent/AP838A/en active
- 1997-05-04 EG EG37797A patent/EG24401A/xx active
- 1997-05-05 ID IDP971490A patent/ID17504A/id unknown
- 1997-05-05 AR ARP970101855A patent/AR007003A1/es unknown
- 1997-05-06 ZA ZA973875A patent/ZA973875B/xx unknown
- 1997-05-06 MY MYPI97001988A patent/MY128051A/en unknown
- 1997-05-06 UY UY24543A patent/UY24543A1/es not_active IP Right Cessation
- 1997-05-06 ME MEP-1997-173A patent/ME00901B/me unknown
- 1997-05-06 DZ DZ970068A patent/DZ2221A1/fr active
- 1997-05-06 MA MA24594A patent/MA26427A1/fr unknown
- 1997-05-06 YU YU17397A patent/YU49398B/sh unknown
- 1997-05-06 TN TNTNSN97073A patent/TNSN97073A1/fr unknown
- 1997-05-07 HR HR970235A patent/HRP970235B1/xx not_active IP Right Cessation
1998
- 1998-10-23 IS IS4878A patent/IS2301B/is unknown
- 1998-10-30 OA OA9800205A patent/OA10908A/fr unknown
- 1998-11-03 BG BG102893A patent/BG63601B1/bg unknown
- 1998-11-06 NO NO19985193A patent/NO312513B1/no not_active IP Right Cessation
1999
- 1999-07-12 HK HK99102956A patent/HK1017893A1/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
NZ332219A (en)	2005-02-25
JP3102896B2 (ja)	2000-10-23
PL188164B1 (pl)	2004-12-31
EG24401A (en)	2009-04-29
YU17397A (sh)	2000-10-30
DE69720719T2 (de)	2003-11-06
EA199800909A1 (ru)	1999-04-29
OA10908A (en)	2001-10-26
HUP9902808A2 (hu)	2000-03-28
JPH11509865A (ja)	1999-08-31
NZ508303A (en)	2001-07-27
DK0904273T3 (da)	2003-07-07
NO985193L (no)	1998-11-06
YU49398B (sh)	2005-11-28
MA26427A1 (fr)	2004-12-20
SK150598A3 (en)	2000-03-13
IL126590A0 (en)	1999-08-17
UY24543A1 (es)	2000-09-29
CN1092658C (zh)	2002-10-16
EP0904273B1 (fr)	2003-04-09
SI0904273T1 (en)	2003-08-31
HU229057B1 (en)	2013-07-29
TW427989B (en)	2001-04-01
EA001180B1 (ru)	2000-10-30
EP0904273A1 (fr)	1999-03-31
DE69720719D1 (de)	2003-05-15
AP838A (en)	2000-05-03
BG63601B1 (bg)	2002-06-28
UA47467C2 (uk)	2002-07-15
WO1997042190A1 (fr)	1997-11-13
MY128051A (en)	2007-01-31
ES2192264T3 (es)	2003-10-01
HN1997000040A (es)	1997-06-05
IS2301B (is)	2007-10-15
HRP970235A2 (en)	1998-06-30
IS4878A (is)	1998-10-23
ME00901B (me)	2005-11-28
AR007003A1 (es)	1999-10-13
TNSN97073A1 (fr)	2005-03-15
CO4940465A1 (es)	2000-07-24
CN1216990A (zh)	1999-05-19
KR20000010822A (ko)	2000-02-25
PL329880A1 (en)	1999-04-12
AP9700978A0 (en)	1997-07-31
ZA973875B (en)	1998-11-06
BG102893A (en)	1999-09-30
PT904273E (pt)	2003-06-30
US6110918A (en)	2000-08-29
CZ349498A3 (cs)	1999-09-15
AU730856B2 (en)	2001-03-15
ID17504A (id)	1998-01-08
IL126590A (en)	2001-11-25
CA2252895A1 (fr)	1997-11-13
KR100333214B1 (ko)	2002-06-20
CZ289216B6 (cs)	2001-12-12
HUP9902808A3 (en)	2000-04-28
AU730856C (en)	2001-11-15
CA2252895C (fr)	2002-08-20
GT199700042A (es)	1998-10-02
HRP970235B1 (en)	2002-08-31
AU1936897A (en)	1997-11-26
HK1017893A1 (en)	1999-12-03
SK282674B6 (sk)	2002-11-06
NO985193D0 (no)	1998-11-06
BR9708932A (pt)	1999-08-03
NO312513B1 (no)	2002-05-21
TR199802241T2 (fr)	1999-02-22
ATE236902T1 (de)	2003-04-15

Publication	Publication Date	Title
DZ2221A1 (fr)	2002-12-03	Trihydrate de mésylate de 5-(2-(4-(1,2-benzisothiazole-3-yi)-1-pipérazinyl)-éthyl)-6-chloro-1,3-dihydro-2h-indole-2-one, procédé pour sa préparation et compositions pharmaceutiques le contenant.
MA26432A1 (fr)	2004-12-20	Derives de 2-(2-oxo-ethylidene)-imidazolidine-4-one, procede pour leur preparation et compositions pharmaceutiques les contenant.
DZ2074A1 (fr)	2002-07-22	Formulation nouvelle contenant de la paroxétine, et procédé pour sa préparation.
CH689805A8 (fr)	2000-02-29	Méthanesulfonate de paroxétine, procédé pour sa préparation et compositions pharmaceutiques le contenant.
RU93043528A (ru)	1996-09-20	Моногидрат 5-(2-(4-(1,2-бензотиазол-3-ил)-1-пиперазинил)этил)-6-хлор-1,3-дигидро-2н-индол-2-он хлоргидрата, способ его получения, фармацевтическая композиция, способ лечения
DZ2300A1 (fr)	2002-12-25	Dérivés 6,5-hétérobicycliques substitués, procédé pour leur préparation et compositions pharmaceutiques les contenant.
DZ2299A1 (fr)	2002-12-25	Dérivés 6,6-hétérobicycliques substitués, procédé pour leur préparation et compositions pharmaceutiques les contenant.
MA26430A1 (fr)	2004-12-20	4 (3h)-quinazolinones 2,3-disubstituees nouvelles, procede pour leur preparation et compositions pharmaceutiques les contenant
MA26687A1 (fr)	2004-12-20	4-carboxyamino-2-methyl-1,2,3,4-tetrahydroquinoleines, procede pour leur preparation et compositions pharmaceutiques les contenant
MA26598A1 (fr)	2004-12-20	4-(2-ceto-1-benzimidazolinyl) piperidines nouvelles, procede pour leur préparation et compositions pharmaceutiques les contenant
MA26526A1 (fr)	2004-12-20	Derives d'indole inhibiteurs de cyclo-oxygenase, procede pour leur preparation et compositions pharmaceutiques les contenant.
MA26536A1 (fr)	2004-12-20	Association de compositions pharmaceutiques d'atorvastatine et d'agents antihypertensifs, et procede pour leur preparation.
FR2740136B1 (fr)	1998-01-09	Derives d'indolin-2-one, procede pour leur preparation et les compositions pharmaceutiques les contenant
MA26499A1 (fr)	2004-12-20	Derives de tetrazole, procede pour leur preparation et compositions pharmaceutiques les contenant .
MA26559A1 (fr)	2004-12-20	Derives de d-proline, procede pour leur preparation, compositions pharmaceutiques les contenant et leur utilisation
FI933804A0 (fi)	1993-08-31	Monohydrat av 5-(2-(4-(1,2-bensisotiazol-3-yl)-1-piperazinyl)etyl-6-klor-1,3-dihydro-2h-indol-2-onkhydroklorid
DZ2523A1 (fr)	2003-02-01	Formulations pharmaceutiques contenant du voriconazole et procédé pour leur préparation.
MA26519A1 (fr)	2004-12-20	Derives d'azetidinylpropylpiperidine, procede pour leur preparation et compositions pharmaceutiques les contenant.
DZ2894A1 (fr)	2003-12-15	Compositions pharmaceutiques contenant des dérivésde pyridol Ä1,2-AÜpyrazine et procédé pour leur p réparation.
MA26523A1 (fr)	2004-12-20	Modification thermodynamiquement stable de 1-(4-carbazolyloxy)-3-(2-(2-methoxyphenoxy) ethylamino)-2-propanole, procede pour sa preparation et compositions pharmaceutiques le comprenant
MA26582A1 (fr)	2004-12-20	Derives de thiazolidinedione nouveau, procede pour sa preparation et composition pharmaceutique le contenant
DZ2948A1 (fr)	2004-03-15	Dérivé d'indole nouveau, procédé pour sa préparation et compositions pharmaceutiques le contenant.
MA26609A1 (fr)	2004-12-20	Derives de retiferol, procede pour leur preparation, compositions pharmaceutiques les contenant et leur utilisation
DZ2954A1 (fr)	2004-06-20	Antagoniste des recepteurs de vitronectine, procédé pour sa préparation et compositions pharmaceutiques le contenant.
FR2728901B1 (fr)	1997-03-28	Derives de phenyl-4-thiazoles substitues, procede pour leur preparation et compositions pharmaceutiques les contenant