ZA943381B - 19-nor steroids having a phenoxyalkylsulphonamide or phenoxyalkylsulphonylurea chain in position 11beta preparation process and intermediates use as medicaments and pharmaceutical compositions containing them - Google Patents

19-nor steroids having a phenoxyalkylsulphonamide or phenoxyalkylsulphonylurea chain in position 11beta preparation process and intermediates use as medicaments and pharmaceutical compositions containing them

Info

Publication number: ZA943381B
Authority: ZA; South Africa
Prior art keywords: radical; medicaments; compositions containing; alkyl; phenoxyalkylsulphonylurea
Prior art date: 1993-06-17

Application number

ZA943381A

Other languages

English (en)

Inventor

Francois Nique

Jean-Georges Teutsch

Patrick Van De Velde

Original Assignee

Roussel Uclaf

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-06-17

Filing date

1994-05-17

Publication date

1995-05-17

1994-05-17 Application filed by Roussel Uclaf filed Critical Roussel Uclaf

1995-05-17 Publication of ZA943381B publication Critical patent/ZA943381B/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0077—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom
- C07J41/0083—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom substituted in position 11-beta by an optionally substituted phenyl group not further condensed with other rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/04—Drugs for genital or sexual disorders; Contraceptives for inducing labour or abortion; Uterotonics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/26—Androgens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/28—Antiandrogens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/32—Antioestrogens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
- A61P5/42—Drugs for disorders of the endocrine system of the suprarenal hormones for decreasing, blocking or antagonising the activity of mineralocorticosteroids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
- A61P5/44—Glucocorticosteroids; Drugs increasing or potentiating the activity of glucocorticosteroids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
- A61P5/46—Drugs for disorders of the endocrine system of the suprarenal hormones for decreasing, blocking or antagonising the activity of glucocorticosteroids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0051—Estrane derivatives
- C07J1/0059—Estrane derivatives substituted in position 17 by a keto group
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0072—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the A ring of the steroid being aromatic
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Diabetes (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Hematology (AREA)
Physical Education & Sports Medicine (AREA)
Immunology (AREA)
Obesity (AREA)
Orthopedic Medicine & Surgery (AREA)
Rheumatology (AREA)
Emergency Medicine (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Pregnancy & Childbirth (AREA)
Gynecology & Obstetrics (AREA)
Neurosurgery (AREA)
Urology & Nephrology (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Vascular Medicine (AREA)
Anesthesiology (AREA)
Child & Adolescent Psychology (AREA)
Dermatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Steroid Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

ZA943381A 1993-06-17 1994-05-17 19-nor steroids having a phenoxyalkylsulphonamide or phenoxyalkylsulphonylurea chain in position 11beta preparation process and intermediates use as medicaments and pharmaceutical compositions containing them ZA943381B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR9307310A FR2706454B1 (fr)	1993-06-17	1993-06-17	Nouveaux 19-Nor stéroïdes, procédé et intermédiaires de préparation, application comme médicaments et compositions pharmaceutiques les contenant.

Publications (1)

Publication Number	Publication Date
ZA943381B true ZA943381B (en)	1995-05-17

Family

ID=9448234

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA943381A ZA943381B (en)	1993-06-17	1994-05-17	19-nor steroids having a phenoxyalkylsulphonamide or phenoxyalkylsulphonylurea chain in position 11beta preparation process and intermediates use as medicaments and pharmaceutical compositions containing them

Country Status (16)

Country	Link
US (3)	US5494907A (de)
EP (1)	EP0629635B1 (de)
JP (1)	JP3621132B2 (de)
KR (1)	KR100341427B1 (de)
CN (2)	CN1054856C (de)
AT (1)	ATE150466T1 (de)
AU (1)	AU673919B2 (de)
CA (1)	CA2126158A1 (de)
DE (1)	DE69402114T2 (de)
DK (1)	DK0629635T3 (de)
ES (1)	ES2099551T3 (de)
FR (1)	FR2706454B1 (de)
GR (1)	GR3023107T3 (de)
HU (1)	HUT67308A (de)
RU (1)	RU2140423C1 (de)
ZA (1)	ZA943381B (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE69418744T2 (de) *	1993-03-05	1999-11-11	Akzo Nobel N.V., Arnheim/Arnhem	Verwendung von Pregnanderivaten zur Behandlung von Tumoren
US5679788A (en) *	1993-06-17	1997-10-21	Roussel Uclaf	11 beta-substituted-19 nor-steroids
AU4093799A (en)	1998-05-22	1999-12-13	Board Of Trustees Of The Leland Stanford Junior University	Bifunctional molecules and therapies based thereon
EP1554572B1 (de)	2001-07-25	2009-10-14	Raptor Pharmaceutical Inc.	Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke
US7009052B2 (en) *	2003-03-20	2006-03-07	Warner Lambert Company Llc	Sulfonamide derivatives
EP1675843A1 (de) *	2003-10-14	2006-07-05	Council of Scientific and Industrial Research	(3r, 4r) -trans-3,4-diarylchroman derivaten mit oestroger wirkung
JP3924310B2 (ja) *	2004-09-29	2007-06-06	森永乳業株式会社	高血糖改善のための医薬及び飲食品
EP2671508B1 (de)	2005-04-28	2020-09-16	Proteus Digital Health, Inc.	Pharma-Informatiksystem
CN101098702B (zh) *	2005-05-17	2010-12-29	森永乳业株式会社	改善胰腺功能的药物和食品或饮料
EP1808175B1 (de) *	2005-05-17	2014-11-19	Morinaga Milk Industry Co., Ltd.	Arzneimittel und lebensmittel oder getränke zur verbesserung der pankreasfunktionen
GB0511051D0 (en) *	2005-05-31	2005-07-06	Exxonmobil Chem Patents Inc	Molecular sieve catalyst treatment
US7312198B2 (en) *	2005-07-12	2007-12-25	Essential Skincare, Llc	Protein compositions for promoting wound healing and skin regeneration
EP1945240B1 (de)	2005-09-16	2016-12-28	Raptor Pharmaceutical Inc	Zusammensetzungen mit rezeptor-assoziierten protein (rap) varianten, die für cr-haltige proteine spezifisch sind und ihre verwendungen
US8093233B2 (en) *	2005-09-22	2012-01-10	Morinaga Milk Industry Co., Ltd.	Agent for inhibiting visceral fat accumulation
PT2398500T (pt)	2009-02-20	2019-06-14	2 Bbb Medicines B V	Sistema de entrega de medicamentos à base de glutationas
CA2760945A1 (en)	2009-05-06	2010-11-11	Laboratory Skin Care, Inc.	Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same
CN114957367B (zh) *	2022-05-27	2023-12-29	黄冈人福药业有限责任公司	一种生物法制备睾酮的精制方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR384842A (fr) *	1907-12-09	1908-04-23	Emile Artigue	Plaque photographique auto-retouche
FR471612A (fr) *	1913-05-08	1914-11-05	Zeiss Carl Soc	Lentille collectrice devant etre intercalée entre deux systèmes redresseurs dans les instruments destinés à l'inspection des corps creux
FR2528434B1 (fr) *	1982-06-11	1985-07-19	Roussel Uclaf	Nouveaux 19-nor steroides substitues en 11b et eventuellement en 2, leur procede de preparation et leur application comme medicament
US4978657A (en) *	1981-01-09	1990-12-18	Roussel Uclaf	Novel 11β-substituted-19-nor-steroids
FR2640977A2 (en) *	1982-06-11	1990-06-29	Roussel Uclaf	New position-11 substituted 19-norsteroids and their application as medicinal products.
FR2618783B1 (fr) *	1987-07-30	1991-02-01	Roussel Uclaf	Nouveaux 17-aryle steroides, leurs procedes et des intermediaires de preparation comme medicaments et les compositions pharmaceutiques les renfermant
FR2643638B1 (fr) *	1989-02-24	1991-06-14	Roussel Uclaf	Nouveaux 19-nor steroides ayant en position 11beta une chaine carbonee comportant une fonction amide ou carbamate, leur procede de preparation et les intermediaires de ce procede, leur application comme medicaments et les compositions pharmaceutiques les contenant
ATE162797T1 (de) *	1990-08-14	1998-02-15	Roussel Uclaf	Neue 19-nor steroide, die eine amid tragende gruppe in der 11-beta-stelle haben, ihre herstellung, ihre verwendung als medikamente und pharmazeutische präparate davon
FR2685332A1 (fr) *	1991-12-20	1993-06-25	Roussel Uclaf	Nouveaux 19-nor sterouides ayant en position 11beta une chaine thiocarbonee, leur procede de preparation et les intermediaires et leur application a titre de medicaments.
FR2688004A1 (fr) *	1992-02-27	1993-09-03	Roussel Uclaf	Nouveaux sterouides comportant en position 17 un radical methylene lactone, leur procede et des intermediaires de preparation, leur application comme medicaments.

1993
- 1993-06-17 FR FR9307310A patent/FR2706454B1/fr not_active Expired - Fee Related
1994
- 1994-05-06 HU HU9401427A patent/HUT67308A/hu unknown
- 1994-05-17 ZA ZA943381A patent/ZA943381B/xx unknown
- 1994-05-19 US US08/246,190 patent/US5494907A/en not_active Expired - Lifetime
- 1994-06-16 EP EP94401344A patent/EP0629635B1/de not_active Expired - Lifetime
- 1994-06-16 DK DK94401344.0T patent/DK0629635T3/da active
- 1994-06-16 DE DE69402114T patent/DE69402114T2/de not_active Expired - Lifetime
- 1994-06-16 JP JP15640794A patent/JP3621132B2/ja not_active Expired - Fee Related
- 1994-06-16 ES ES94401344T patent/ES2099551T3/es not_active Expired - Lifetime
- 1994-06-16 KR KR1019940013594A patent/KR100341427B1/ko not_active IP Right Cessation
- 1994-06-16 CN CN94106469A patent/CN1054856C/zh not_active Expired - Fee Related
- 1994-06-16 AT AT94401344T patent/ATE150466T1/de not_active IP Right Cessation
- 1994-06-16 RU RU94022277A patent/RU2140423C1/ru not_active IP Right Cessation
- 1994-06-17 AU AU64763/94A patent/AU673919B2/en not_active Ceased
- 1994-06-17 CA CA002126158A patent/CA2126158A1/fr not_active Abandoned
1995
- 1995-05-19 US US08/445,385 patent/US5556845A/en not_active Expired - Lifetime
- 1995-08-08 US US08/512,284 patent/US5705494A/en not_active Expired - Lifetime
1997
- 1997-04-11 GR GR960402896T patent/GR3023107T3/el unknown
1998
- 1998-05-09 CN CN98108945A patent/CN1271734A/zh active Pending

Also Published As

Publication number	Publication date
KR950000729A (ko)	1995-01-03
EP0629635A1 (de)	1994-12-21
EP0629635B1 (de)	1997-03-19
US5556845A (en)	1996-09-17
RU94022277A (ru)	1996-04-20
JP3621132B2 (ja)	2005-02-16
GR3023107T3 (en)	1997-07-30
DK0629635T3 (da)	1997-09-22
AU673919B2 (en)	1996-11-28
ES2099551T3 (es)	1997-05-16
AU6476394A (en)	1994-12-22
FR2706454A1 (fr)	1994-12-23
US5494907A (en)	1996-02-27
DE69402114T2 (de)	1997-09-11
US5705494A (en)	1998-01-06
HU9401427D0 (en)	1994-08-29
CN1101915A (zh)	1995-04-26
DE69402114D1 (de)	1997-04-24
CN1271734A (zh)	2000-11-01
FR2706454B1 (fr)	1995-09-15
KR100341427B1 (ko)	2002-11-14
RU2140423C1 (ru)	1999-10-27
CN1054856C (zh)	2000-07-26
ATE150466T1 (de)	1997-04-15
CA2126158A1 (fr)	1994-12-18
JPH0717996A (ja)	1995-01-20
HUT67308A (en)	1995-03-28

Publication	Publication Date	Title
ZA943381B (en)	1995-05-17	19-nor steroids having a phenoxyalkylsulphonamide or phenoxyalkylsulphonylurea chain in position 11beta preparation process and intermediates use as medicaments and pharmaceutical compositions containing them
DE69025104D1 (de)	1996-03-14	Thiazolderivate, Verfahren zur Ihrer Herstellung und pharmazeutische Zusammensetzungen, die sie enthalten
PH23607A (en)	1989-09-11	Amide derivatives and pharmaceutical composition containing said compounds
AU5007290A (en)	1990-08-30	New 19-nor steroids having in position 11beta a carbonated chain containing an amide or carbamate function, their preparation process and the intermediates of this process, their use as medicaments and the pharmaceutical compositions containing them
DE69101673D1 (de)	1994-05-19	N-substituierte Alpha-Mercaptoalkylaminderivate, Verfahren zu ihrer Herstellung und hergestellte Zwischenprodukte, ihre Verwendung als Arzneimittel und diese enthaltende Zusammensetzungen.
EG16546A (en)	1990-10-30	Therapeutic agents
HUT55349A (en)	1991-05-28	Process for producing benzanilide derivatives and pharmaceutical compositions comprising same
ZA903139B (en)	1991-06-26	Derivatives of 4-phenylmethyl-1h-indole,process and intermediates of preparation,application as medicaments and compositions containing them
DE69011901D1 (de)	1994-10-06	1-Arylsulfonyl-2-piperidinon-Derivate, Verfahren und Zwischenprodukte zu ihrer Herstellung, ihre Verwendung als Arzneimittel und sie enthaltende Zusammensetzungen.
ZA803245B (en)	1981-06-24	New derivatives of xanthine
MX9206149A (es)	1993-08-01	N-(mercaptoacil)amino acidos, metodos para su preparcion y uso terapeutico, y composiciones farmaceuticas que los contienen
NO933691L (no)	1993-10-13	Tiokarbamatsulfoksydsammensetning for avholdenhet fra inntakelse av etanol
KR950704322A (ko)	1995-11-17	스피로푸라논 유도체 및 그의 신경변성 질환 치료 용도(Spirofuranone Derivatives and Their Use in the Treatment of Neurodegenerative Disorders)
DE3782619D1 (de)	1992-12-17	1-hydroxyalkylxanthine, verfahren zu ihrer herstellung und sie enthaltende medikamente.
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