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ZA859462B - New pteridines,processes for preparing them and their use as intermediate products or as pharmaceutical compositions - Google Patents

New pteridines,processes for preparing them and their use as intermediate products or as pharmaceutical compositions

Info

Publication number
ZA859462B
ZA859462B ZA859462A ZA859462A ZA859462B ZA 859462 B ZA859462 B ZA 859462B ZA 859462 A ZA859462 A ZA 859462A ZA 859462 A ZA859462 A ZA 859462A ZA 859462 B ZA859462 B ZA 859462B
Authority
ZA
South Africa
Prior art keywords
preparing
processes
pharmaceutical compositions
intermediate products
pteridines
Prior art date
Application number
ZA859462A
Other languages
English (en)
Inventor
Josef Roch
Armin Heckel
Josef Nickl
Erich Mueller
Berthold Narr
Rainer Zimmermann
Hans Weisenberger
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of ZA859462B publication Critical patent/ZA859462B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D475/00—Heterocyclic compounds containing pteridine ring systems
    • C07D475/06—Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4
    • C07D475/08—Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4 with a nitrogen atom directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
ZA859462A 1984-12-12 1985-12-11 New pteridines,processes for preparing them and their use as intermediate products or as pharmaceutical compositions ZA859462B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19843445298 DE3445298A1 (de) 1984-12-12 1984-12-12 Neue pteridine, verfahren zu ihrer herstellung und deren verwendung als zwischenprodukte oder als arzneimittel

Publications (1)

Publication Number Publication Date
ZA859462B true ZA859462B (en) 1987-07-29

Family

ID=6252576

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA859462A ZA859462B (en) 1984-12-12 1985-12-11 New pteridines,processes for preparing them and their use as intermediate products or as pharmaceutical compositions

Country Status (15)

Country Link
EP (1) EP0185259A3 (xx)
JP (1) JPS61140585A (xx)
AU (1) AU576924B2 (xx)
CA (1) CA1252783A (xx)
DE (1) DE3445298A1 (xx)
DK (1) DK161327C (xx)
ES (1) ES8707238A1 (xx)
FI (1) FI82696C (xx)
GR (1) GR852996B (xx)
IL (1) IL77294A (xx)
NO (1) NO161373C (xx)
NZ (1) NZ214522A (xx)
PH (1) PH24451A (xx)
PT (1) PT81650B (xx)
ZA (1) ZA859462B (xx)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7276506B2 (en) 1998-12-28 2007-10-02 4 Aza Bioscience Nv Immunosuppressive effects of pteridine derivatives
PL374259A1 (en) * 2001-06-28 2005-10-03 Pliva D.D. Novel heterocyclic compounds as selective bacterial dhfr inhibitors and their uses thereof
DE10202468A1 (de) * 2002-01-23 2004-09-30 Faustus Forschungs Cie. Translational Cancer Research Gmbh Pteridinderivate, Verfahren zu deren Herstellung und ihre Verwendung
ATE376421T1 (de) * 2003-08-29 2007-11-15 4 Aza Ip Nv Immunosuppressive wirkungen von pteridinderivativen
GB2407089A (en) * 2003-10-17 2005-04-20 4 Aza Bioscience Nv Pteridine derivatives
JP2007508355A (ja) * 2003-10-17 2007-04-05 ４・アー・ゼット・アー・バイオサイエンス・ナムローゼ・フエンノートシャップ 複素環−置換プテリジン誘導体と治療におけるその利用
JP2007526323A (ja) * 2004-03-04 2007-09-13 ニューロジェン・コーポレーション アリールアルキルアミノ置換キナゾリン類縁体
DE102004057645A1 (de) 2004-11-29 2006-06-01 Boehringer Ingelheim Pharma Gmbh & Co. Kg Substituierte Pteridine zur Behandlung von entzündlichen Erkrankungen
DE102004057618A1 (de) 2004-11-29 2006-06-01 Boehringer Ingelheim Pharma Gmbh & Co. Kg Substituierte Pteridine zur Behandlung von entzündlichen Erkrankungen
DE102004057595A1 (de) 2004-11-29 2006-06-08 Boehringer Ingelheim Pharma Gmbh & Co. Kg Substituierte Pteridine zur Behandlung von entzündlichen Erkrankungen
DE102004057594A1 (de) 2004-11-29 2006-06-08 Boehringer Ingelheim Pharma Gmbh & Co. Kg Substitueirte Pteridine zur Behandlung von entzündlichen Erkrankungen
EP1954699B1 (en) * 2005-11-22 2012-09-19 Kudos Pharmaceuticals Ltd PYRIDO-, PYRAZO- AND PYRIMIDOPYRIMIDINE DERIVATIVES AS mTOR INHIBITORS
RU2445315C2 (ru) * 2005-11-22 2012-03-20 Кудос Фармасьютиклз Лимитед ПРОИЗВОДНЫЕ ПИРИДО-, ПИРАЗО- И ПИРИМИДО-ПИРИМИДИНА И ИХ ПРИМЕНЕНИЕ В КАЧЕСТВЕ ИНГИБИТОРОВ mTOR
WO2007135026A2 (de) 2006-05-24 2007-11-29 Boehringer Ingelheim International Gmbh Substituierte pteridine als therapeutika
WO2008009079A2 (en) 2006-07-20 2008-01-24 Gilead Sciences, Inc. Substituted pteridines useful for the treatment and prevention of viral infections
WO2008009078A2 (en) 2006-07-20 2008-01-24 Gilead Sciences, Inc. 4,6-dl- and 2,4,6-trisubstituted quinazoline derivatives useful for treating viral infections
RS55881B1 (sr) 2006-08-23 2017-08-31 Kudos Pharm Ltd 2-metilmorfolin pirido-,pirazo- i pirimido-pirimidin derivati kao inhibitori mtor-a
UY31917A (es) 2008-06-20 2010-01-29 Astrazeneca Ab Compuestos de pirido-pirimidina inhibidores de mtor, composiciones farmaceuticas que los comprenden, procesos para su preparación y su uso como medicamento.
ES2801380T3 (es) 2015-03-04 2021-01-11 Gilead Sciences Inc Compuestos de 4,6-diamino-pirido [3,2-d] pirimidina y su utilización como moduladores de receptor de tipo toll
WO2018045150A1 (en) 2016-09-02 2018-03-08 Gilead Sciences, Inc. 4,6-diamino-pyrido[3,2-d]pyrimidine derivaties as toll like receptor modulators
KR102268448B1 (ko) 2016-09-02 2021-06-22 길리애드 사이언시즈, 인코포레이티드 톨 유사 수용체 조정제 화합물
TW202212339A (zh) 2019-04-17 2022-04-01 美商基利科學股份有限公司 類鐸受體調節劑之固體形式
TW202210480A (zh) 2019-04-17 2022-03-16 美商基利科學股份有限公司 類鐸受體調節劑之固體形式
TW202115056A (zh) 2019-06-28 2021-04-16 美商基利科學股份有限公司 類鐸受體調節劑化合物的製備方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3159628A (en) * 1962-05-28 1964-12-01 Smith Kline French Lab Pteridine-5-oxide derivatives
DE3323932A1 (de) * 1983-07-02 1985-01-10 Dr. Karl Thomae Gmbh, 7950 Biberach Neue 2-piperazino-pteridine, verfahren zu ihrer herstellung und diese verbindung enthaltende arzneimittel

Also Published As

Publication number Publication date
FI854862A0 (fi) 1985-12-10
NZ214522A (en) 1988-07-28
ES8707238A1 (es) 1987-07-16
PT81650B (pt) 1988-04-21
NO854965L (no) 1986-06-13
DK161327C (da) 1991-12-09
FI82696C (fi) 1991-04-10
CA1252783A (en) 1989-04-18
NO161373C (no) 1989-08-09
IL77294A (en) 1989-02-28
DK572685D0 (da) 1985-12-11
FI854862A (fi) 1986-06-13
DE3445298A1 (de) 1986-06-12
FI82696B (fi) 1990-12-31
AU576924B2 (en) 1988-09-08
DK161327B (da) 1991-06-24
PH24451A (en) 1990-06-25
NO161373B (no) 1989-05-02
ES549806A0 (es) 1987-07-16
EP0185259A3 (de) 1989-03-01
EP0185259A2 (de) 1986-06-25
GR852996B (xx) 1986-04-16
JPS61140585A (ja) 1986-06-27
AU5123285A (en) 1986-06-19
PT81650A (de) 1986-01-01
DK572685A (da) 1986-06-13

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