ZA787156B - 4a-aryl-octahydro-1h-2-pyrindines - Google Patents
4a-aryl-octahydro-1h-2-pyrindinesInfo
- Publication number
- ZA787156B ZA787156B ZA787156A ZA787156A ZA787156B ZA 787156 B ZA787156 B ZA 787156B ZA 787156 A ZA787156 A ZA 787156A ZA 787156 A ZA787156 A ZA 787156A ZA 787156 B ZA787156 B ZA 787156B
- Authority
- ZA
- South Africa
- Prior art keywords
- pyrindines
- octahydro
- aryl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pain & Pain Management (AREA)
- Public Health (AREA)
- Rheumatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US86489977A | 1977-12-27 | 1977-12-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA787156B true ZA787156B (en) | 1980-08-27 |
Family
ID=25344312
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA787156A ZA787156B (en) | 1977-12-27 | 1978-12-20 | 4a-aryl-octahydro-1h-2-pyrindines |
Country Status (24)
| Country | Link |
|---|---|
| EP (1) | EP0002937A1 (pl) |
| JP (1) | JPS5498770A (pl) |
| AR (1) | AR221352A1 (pl) |
| AU (1) | AU4286678A (pl) |
| BE (1) | BE872990A (pl) |
| BG (1) | BG30927A3 (pl) |
| CA (1) | CA1105026A (pl) |
| CS (1) | CS203940B2 (pl) |
| DD (1) | DD141156A5 (pl) |
| DK (1) | DK577078A (pl) |
| ES (1) | ES476385A1 (pl) |
| FI (1) | FI783992A (pl) |
| FR (1) | FR2413370A1 (pl) |
| GB (1) | GB2010806A (pl) |
| GR (1) | GR70349B (pl) |
| IL (1) | IL56268A0 (pl) |
| IT (1) | IT1101682B (pl) |
| LU (1) | LU80719A1 (pl) |
| NZ (1) | NZ189230A (pl) |
| PL (1) | PL117572B1 (pl) |
| PT (1) | PT68934A (pl) |
| RO (1) | RO75805A (pl) |
| SU (1) | SU841586A3 (pl) |
| ZA (1) | ZA787156B (pl) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4537963A (en) * | 1981-12-28 | 1985-08-27 | E. I. Du Pont De Nemours And Company | Intermediates for octahydrobenzofuro[3,2-E]isoquinolines |
| US4415736A (en) * | 1981-12-28 | 1983-11-15 | E. I. Du Pont De Nemours & Co. | Certain tetrahydropyridine intermediates |
| US4579952A (en) * | 1981-12-28 | 1986-04-01 | E. I. Du Pont De Nemours And Company | Intermediates for octahydrobenzofuro[3,2-e]isoquinolines |
| FR2617481B1 (fr) * | 1987-07-03 | 1989-11-10 | Roussel Uclaf | Nouveaux derives de la tetrahydropyridine, leur procede de preparation et les intermediaires de preparation, leur application comme medicaments et les compositions pharmaceutiques les renfermant |
| US8598164B2 (en) | 2010-05-06 | 2013-12-03 | Vertex Pharmaceuticals Incorporated | Heterocyclic chromene-spirocyclic piperidine amides as modulators of ion channels |
| EP2670752B1 (en) | 2011-02-02 | 2016-03-16 | Vertex Pharmaceuticals Incorporated | Pyrrolopyrazine-spirocyclic piperidine amides as modulators of ion channels |
| CA2827311A1 (en) | 2011-02-18 | 2012-08-23 | Vertex Pharmaceuticals Incorporated | Chroman-spirocyclic piperidine amides as modulators of ion channels |
| JP6088443B2 (ja) | 2011-03-14 | 2017-03-01 | バーテックス ファーマシューティカルズ インコーポレイテッドＶｅｒｔｅｘ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｃｏｒｐｏｒａｔｅｄ | イオンチャネルのモジュレーターとしてのモルホリン−スピロ環式ピペリジンアミド |
| CA2917198C (en) * | 2013-07-10 | 2022-06-07 | Vertex Pharmaceuticals Incorporated | Fused piperidine amides as modulators of ion channels |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA734895B (en) * | 1972-07-20 | 1974-06-26 | Du Pont | Analgesigs and/or narcotic antagonists |
| DE2336559A1 (de) * | 1972-07-20 | 1974-01-31 | Du Pont | 4a-aryl-trans-decahydrochinoline und verfahren zu ihrer herstellung |
| PT67194B (en) * | 1976-11-02 | 1979-03-23 | Lilly Co Eli | Process for preparing 4a-aryl-octahydro-1h-2-pyrindines |
-
1978
- 1978-12-19 BG BG041785A patent/BG30927A3/xx unknown
- 1978-12-19 NZ NZ189230A patent/NZ189230A/xx unknown
- 1978-12-19 PL PL1978211919A patent/PL117572B1/pl unknown
- 1978-12-19 PT PT68934A patent/PT68934A/pt unknown
- 1978-12-20 GR GR57949A patent/GR70349B/el unknown
- 1978-12-20 CA CA318,284A patent/CA1105026A/en not_active Expired
- 1978-12-20 AR AR274886A patent/AR221352A1/es active
- 1978-12-20 ZA ZA787156A patent/ZA787156B/xx unknown
- 1978-12-20 RO RO7895989A patent/RO75805A/ro unknown
- 1978-12-21 GB GB7849437A patent/GB2010806A/en not_active Withdrawn
- 1978-12-21 FR FR7835977A patent/FR2413370A1/fr not_active Withdrawn
- 1978-12-21 EP EP78300879A patent/EP0002937A1/en not_active Withdrawn
- 1978-12-21 IL IL56268A patent/IL56268A0/xx unknown
- 1978-12-22 LU LU80719A patent/LU80719A1/xx unknown
- 1978-12-22 IT IT31268/78A patent/IT1101682B/it active
- 1978-12-22 DK DK577078A patent/DK577078A/da not_active Application Discontinuation
- 1978-12-22 AU AU42866/78A patent/AU4286678A/en active Pending
- 1978-12-22 CS CS788854A patent/CS203940B2/cs unknown
- 1978-12-22 BE BE1009211A patent/BE872990A/xx unknown
- 1978-12-25 JP JP16448778A patent/JPS5498770A/ja active Pending
- 1978-12-26 SU SU782701053A patent/SU841586A3/ru active
- 1978-12-27 ES ES476385A patent/ES476385A1/es not_active Expired
- 1978-12-27 FI FI783992A patent/FI783992A/fi unknown
- 1978-12-27 DD DD78210204A patent/DD141156A5/de unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES476385A1 (es) | 1979-11-16 |
| PL211919A1 (pl) | 1979-09-10 |
| NZ189230A (en) | 1981-05-15 |
| RO75805A (ro) | 1981-02-28 |
| IT1101682B (it) | 1985-10-07 |
| BE872990A (fr) | 1979-06-22 |
| GB2010806A (en) | 1979-07-04 |
| CA1105026A (en) | 1981-07-14 |
| PL117572B1 (en) | 1981-08-31 |
| GR70349B (pl) | 1982-09-23 |
| AR221352A1 (es) | 1981-01-30 |
| CS203940B2 (en) | 1981-03-31 |
| PT68934A (en) | 1979-01-01 |
| EP0002937A1 (en) | 1979-07-11 |
| LU80719A1 (fr) | 1979-04-13 |
| DD141156A5 (de) | 1980-04-16 |
| AU4286678A (en) | 1979-07-05 |
| IT7831268A0 (it) | 1978-12-22 |
| IL56268A0 (en) | 1979-03-12 |
| SU841586A3 (ru) | 1981-06-23 |
| FI783992A (fi) | 1979-06-28 |
| JPS5498770A (en) | 1979-08-03 |
| BG30927A3 (en) | 1981-09-15 |
| FR2413370A1 (fr) | 1979-07-27 |
| DK577078A (da) | 1979-06-28 |
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