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ZA200004473B - Barbituric acid derivative and preventive and therapeutic agent for bone and cartilage containing the same. - Google Patents

Barbituric acid derivative and preventive and therapeutic agent for bone and cartilage containing the same.

Info

Publication number
ZA200004473B
ZA200004473B ZA200004473A ZA200004473A ZA200004473B ZA 200004473 B ZA200004473 B ZA 200004473B ZA 200004473 A ZA200004473 A ZA 200004473A ZA 200004473 A ZA200004473 A ZA 200004473A ZA 200004473 B ZA200004473 B ZA 200004473B
Authority
ZA
South Africa
Prior art keywords
preventive
bone
same
therapeutic agent
acid derivative
Prior art date
Application number
ZA200004473A
Other languages
English (en)
Inventor
Kunikazu Sakai
Yusuke Sotah
Original Assignee
Hoechst Marion Roussel Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Marion Roussel Inc filed Critical Hoechst Marion Roussel Inc
Publication of ZA200004473B publication Critical patent/ZA200004473B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • A61K31/515Barbituric acids; Derivatives thereof, e.g. sodium pentobarbital
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/60Three or more oxygen or sulfur atoms
    • C07D239/62Barbituric acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA200004473A 1998-03-27 2000-08-29 Barbituric acid derivative and preventive and therapeutic agent for bone and cartilage containing the same. ZA200004473B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP10100355A JPH11279157A (ja) 1998-03-27 1998-03-27 バルビツール酸誘導体およびそれらからなる骨・軟骨疾患予防・治療薬

Publications (1)

Publication Number Publication Date
ZA200004473B true ZA200004473B (en) 2001-05-30

Family

ID=14271794

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200004473A ZA200004473B (en) 1998-03-27 2000-08-29 Barbituric acid derivative and preventive and therapeutic agent for bone and cartilage containing the same.

Country Status (20)

Country Link
US (1) US6498164B1 (xx)
EP (1) EP1064269A1 (xx)
JP (1) JPH11279157A (xx)
KR (1) KR20010042182A (xx)
CN (1) CN1295565A (xx)
AU (1) AU759249B2 (xx)
BR (1) BR9909139A (xx)
CA (1) CA2324584A1 (xx)
CZ (1) CZ20003460A3 (xx)
EA (1) EA200000992A1 (xx)
HU (1) HUP0101505A3 (xx)
IL (1) IL138433A0 (xx)
NO (1) NO20004798L (xx)
NZ (1) NZ506616A (xx)
PL (1) PL343433A1 (xx)
SK (1) SK14032000A3 (xx)
TR (1) TR200002785T2 (xx)
WO (1) WO1999050252A2 (xx)
YU (1) YU57800A (xx)
ZA (1) ZA200004473B (xx)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20060130681A (ko) * 2004-02-26 2006-12-19 이노텍 파마슈티컬스 코포레이션 테트라사이클릭 락탐 유도체 및 이것의 용도
CN102070623B (zh) * 2010-12-20 2012-07-25 新乡医学院 一种巴比妥酸衍生物及其制备方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2921072A (en) * 1956-10-18 1960-01-12 Jr Edgar A Ferguson Nicotinic acid substituents of barbituric acid
GB1339748A (en) * 1970-07-02 1973-12-05 Ici Ltd Pyrimidine derivatives
JPS5829281B2 (ja) * 1974-06-04 1983-06-22 日本曹達株式会社 バルビツ−ル酸系除草剤
US4695673A (en) * 1985-11-20 1987-09-22 Stauffer Chemical Company Process for the production of acylated 1,3-dicarbonyl compounds
US4797147A (en) * 1986-06-09 1989-01-10 Stauffer Chemical Company Herbicidal method and composition utilizing certain 5-(2-substituted benzoyl)-barbituric acids
US4938796A (en) * 1987-07-06 1990-07-03 Ici Americas Inc. Herbicidal compositions of acylated 1,3-dicarbonyl herbicides and antidotes therefor
JP2588779B2 (ja) * 1989-09-18 1997-03-12 富士写真フイルム株式会社 電子写真式製版用印刷原版
US5102760A (en) * 1989-09-18 1992-04-07 Fuji Photo Film Co., Ltd. Electrophotographic photoreceptor and electrophotographic printing plate precursor comprising phthalocyanine pigment and thiobarbituric acid derivative
JP2588780B2 (ja) * 1989-09-26 1997-03-12 富士写真フイルム株式会社 電子写真感光体
JPH03179361A (ja) * 1989-12-07 1991-08-05 Fuji Photo Film Co Ltd 光導電性組成物およびそれを用いた電子写真感光材料
US5141943A (en) * 1990-04-12 1992-08-25 Brown University Research Foundation 5-benzyl barbiturate derivatives
NL9001075A (xx) * 1990-05-04 1991-12-02 Duphar Int Res
DK0517660T3 (da) * 1991-06-05 1997-10-27 Ciba Geigy Ag Benzo-1,2,3-thiadiazol-derivater.
WO1996025402A1 (en) * 1995-02-13 1996-08-22 Gulliya Kirpal S Novel uses for barbituric acid analogs
JPH10316608A (ja) * 1997-05-14 1998-12-02 Hoechst Yakuhin Kogyo Kk ポリヒドロキシフェノール誘導体およびそれらからなる骨・軟骨疾患予防・治療剤

Also Published As

Publication number Publication date
AU759249B2 (en) 2003-04-10
WO1999050252A3 (en) 2000-01-13
SK14032000A3 (sk) 2001-03-12
WO1999050252A2 (en) 1999-10-07
KR20010042182A (ko) 2001-05-25
EP1064269A1 (en) 2001-01-03
CN1295565A (zh) 2001-05-16
YU57800A (sh) 2002-10-18
HUP0101505A2 (hu) 2002-03-28
BR9909139A (pt) 2000-12-05
PL343433A1 (en) 2001-08-13
TR200002785T2 (tr) 2001-02-21
US6498164B1 (en) 2002-12-24
NO20004798D0 (no) 2000-09-26
CA2324584A1 (en) 1999-10-07
NO20004798L (no) 2000-11-20
IL138433A0 (en) 2001-10-31
NZ506616A (en) 2003-04-29
AU3726099A (en) 1999-10-18
HUP0101505A3 (en) 2002-06-28
EA200000992A1 (ru) 2001-06-25
JPH11279157A (ja) 1999-10-12
CZ20003460A3 (cs) 2001-08-15

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