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SI1082330T1 - Platinum complex, its preparation and therapeutic application - Google Patents

Platinum complex, its preparation and therapeutic application

Info

Publication number
SI1082330T1
SI1082330T1 SI9930056T SI9930056T SI1082330T1 SI 1082330 T1 SI1082330 T1 SI 1082330T1 SI 9930056 T SI9930056 T SI 9930056T SI 9930056 T SI9930056 T SI 9930056T SI 1082330 T1 SI1082330 T1 SI 1082330T1
Authority
SI
Slovenia
Prior art keywords
preparation
platinum complex
therapeutic application
therapeutic
application
Prior art date
Application number
SI9930056T
Other languages
English (en)
Slovenian (sl)
Inventor
Frantisek Zak
Adolf Mistr
Anna Poulova
Milan Melka
Jaroslav Turanek
Dana Zaluska
Original Assignee
Pliva-Lachema A.S.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pliva-Lachema A.S. filed Critical Pliva-Lachema A.S.
Publication of SI1082330T1 publication Critical patent/SI1082330T1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086—Platinum compounds
    • C07F15/0093—Platinum compounds without a metal-carbon linkage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
SI9930056T 1998-05-27 1999-05-24 Platinum complex, its preparation and therapeutic application SI1082330T1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CZ19981628A CZ288912B6 (cs) 1998-05-27 1998-05-27 Komplex platiny v oxidačním čísle IV, způsob přípravy tohoto komplexu, tento komplex jako léčivo a farmaceutická kompozice tento komplex obsahující
PCT/CZ1999/000015 WO1999061451A1 (en) 1998-05-27 1999-05-24 Platinum complex, its preparation and therapeutic application
EP99920541A EP1082330B1 (en) 1998-05-27 1999-05-24 Platinum complex, its preparation and therapeutic application

Publications (1)

Publication Number Publication Date
SI1082330T1 true SI1082330T1 (en) 2002-08-31

Family

ID=5463562

Family Applications (1)

Application Number Title Priority Date Filing Date
SI9930056T SI1082330T1 (en) 1998-05-27 1999-05-24 Platinum complex, its preparation and therapeutic application

Country Status (24)

Country Link
US (1) US6503943B1 (sk)
EP (1) EP1082330B1 (sk)
JP (1) JP3575686B2 (sk)
CN (1) CN1124279C (sk)
AU (1) AU741380B2 (sk)
BG (1) BG64599B1 (sk)
BR (1) BR9910669B1 (sk)
CA (1) CA2332054C (sk)
CZ (1) CZ288912B6 (sk)
DE (1) DE69901177T2 (sk)
ES (1) ES2175968T3 (sk)
HR (1) HRP20000791B1 (sk)
HU (1) HU224716B1 (sk)
IL (1) IL139529A (sk)
MX (1) MXPA00011621A (sk)
NO (1) NO328930B1 (sk)
PL (1) PL191132B1 (sk)
PT (1) PT1082330E (sk)
RS (1) RS49738B (sk)
RU (1) RU2200164C2 (sk)
SI (1) SI1082330T1 (sk)
SK (1) SK284436B6 (sk)
UA (1) UA56315C2 (sk)
WO (1) WO1999061451A1 (sk)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ2004235A3 (cs) * 2004-02-12 2005-08-17 Pliva-Lachema A. S. Farmaceutická kompozice obsahující jako účinnou látku platinový komplex a způsob výroby této kompozice
CZ296045B6 (cs) * 2003-03-31 2005-12-14 Pliva-Lachema A. S. Farmaceutická kompozice obsahující jako účinnou látku komplex čtyřmocné platiny a způsob její výroby
RS20050714A (sr) * 2003-03-31 2008-04-04 Pliva-Lachema A.S., Farmaceutski preparati koji kao aktivnu suptancu sadrže kompleks platine i postupci za njihovo dobijanje
US20080146555A1 (en) 2004-06-18 2008-06-19 Gpc Biotech, Inc Uses of Kinase Inhibitors and Compositions Thereof
JP2008506463A (ja) * 2004-07-14 2008-03-06 ゲーペーツェー ビオテック アーゲー 可変投与量パッケージシステム
CZ2004945A3 (cs) * 2004-09-08 2006-01-11 Pliva - Lachema A. S. Farmaceutická kompozice pro rektální nebo vaginální podání, zpusob její prípravy a tato kompozice pro pouzití jako lécivo
CZ2004964A3 (cs) * 2004-09-14 2006-03-15 Pliva-Lachema A. S. Perorální farmaceutická kompozice pro cílený transport komplexu platiny do kolorektální oblasti, zpusob její prípravy a tato kompozice pro pouzití jako lécivo
JP2008519859A (ja) * 2004-11-10 2008-06-12 ユニバーシティー オブ サウス フロリダ 標的化した薬物送達のための白金錯体
JP5106098B2 (ja) * 2005-02-28 2012-12-26 エーザイ・アール・アンド・ディー・マネジメント株式会社 スルホンアミド化合物の抗癌剤との新規併用
EP1792622A1 (en) 2005-11-11 2007-06-06 GPC Biotech AG Anti-proliferative combination therapy comprising a platinum-based chemotherapeutic agent and EGFR inhibitors or pyrimidine analogues
CZ300590B6 (cs) * 2006-06-20 2009-06-24 Pliva - Lachema A. S. Farmaceutická kompozice pro injekcní podání
CZ300424B6 (cs) * 2006-06-20 2009-05-13 Pliva - Lachema A. S. Farmaceutická kompozice pro perorální podání
CZ300120B6 (cs) * 2006-06-20 2009-02-11 Pliva - Lachema A. S. Farmaceutická kompozice pro injekcní podání
KR100829173B1 (ko) * 2006-09-19 2008-05-13 광주과학기술원 물에 대한 용해도가 우수한 플라틴 복합체의 포접복합체 및그 제조방법
GB2457452B (en) * 2008-02-12 2010-05-12 Pliva Lachema As Amorphous form of (OC-6-43)-bis(acetate)(1-tricyclo[3,3,1,13,7]decylamine) amminedichloroplatinum (IV)
GB2457454B (en) * 2008-02-12 2010-05-12 Pliva Lachema As Polymorphic crystalline form II of (OC-6-43)-bis(acetate)(1-tricyclo[3,3,1,13,7]decylamine) ammine dichloroplatinum (IV)
GB2457453B (en) * 2008-02-12 2010-05-12 Pliva Lachema As Polymorphic crystalline form III of (OC-6-43)-bis(acetate)(1-tricyclo[3,3,1,13,7]decylamine) ammine dichloroplatinum (IV)
GB2457455B (en) * 2008-02-12 2010-04-21 Pliva Lachema As Polymorphic crystalline form (I) of (OC-6-43)-Bis(Acetato)-1-(Tricyclo[3,3,1,1 (3,7)]Decylamine)Amminedichloroplatinum(IV)
WO2010149666A1 (en) 2009-06-22 2010-12-29 Medexis S.A. Methods for treating neoplasia
WO2011029639A2 (en) 2009-09-08 2011-03-17 Medexis S.A. Compounds and methods for treating neoplasia
US20130303500A1 (en) 2010-07-30 2013-11-14 Medexis S.A. Compounds and methods for treating neoplasia
US10017532B2 (en) 2014-09-03 2018-07-10 Vuab Pharma A.S. Platinum (IV) complex with increased anti-tumor efficacy
CN104984356A (zh) * 2015-05-14 2015-10-21 昆明贵研药业有限公司 赛特铂的环糊精复合物及制备方法
RU2613513C2 (ru) * 2015-07-17 2017-03-16 Федеральное государственное бюджетное учреждение науки Институт проблем химической физики Российской академии наук (ИПХФ РАН) Способ получения комплексов платины (IV) с аминонитроксильными радикалами
RU2726826C2 (ru) * 2016-12-27 2020-07-15 Общество с ограниченной ответственностью "Плат-АН" (ООО "Плат-АН") Композиция на основе аминонитроксильного комплекса платины и доксорубицина и способ лечения опухолей
US20220289781A1 (en) * 2019-09-05 2022-09-15 Vuab Pharma A.S. New platinum iv complexes with substantially increased antitumor efficacy

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0328274B1 (en) * 1988-02-02 1994-10-19 Johnson Matthey, Inc., Pt (IV) complexes
FI905018A0 (fi) * 1989-10-17 1990-10-12 Bristol Myers Squibb Co I vatten och loesningsmedel loesliga axiala hydroxi-och mono- och dikarboxylsyraderivat med stor tumoeraktivitet.
GB9105037D0 (en) * 1991-03-09 1991-04-24 Johnson Matthey Plc Improvements in chemical compounds
JPH10265380A (ja) * 1997-03-17 1998-10-06 Bristol Myers Squibb Co 抗ガン剤

Also Published As

Publication number Publication date
DE69901177D1 (de) 2002-05-08
HRP20000791B1 (en) 2006-07-31
CZ288912B6 (cs) 2001-09-12
RU2200164C2 (ru) 2003-03-10
AU741380B2 (en) 2001-11-29
BR9910669A (pt) 2001-01-30
CA2332054C (en) 2005-06-28
MXPA00011621A (es) 2003-03-12
NO328930B1 (no) 2010-06-21
EP1082330A1 (en) 2001-03-14
HUP0102549A3 (en) 2004-04-28
CN1303388A (zh) 2001-07-11
RS49738B (sr) 2008-04-04
YU71900A (sh) 2002-10-18
HUP0102549A2 (hu) 2001-11-28
NO20005990D0 (no) 2000-11-27
JP3575686B2 (ja) 2004-10-13
PL344346A1 (en) 2001-11-05
WO1999061451A1 (en) 1999-12-02
BG64599B1 (bg) 2005-08-31
SK17732000A3 (sk) 2001-05-10
NO20005990L (no) 2000-11-27
BG104972A (en) 2001-08-31
AU3809399A (en) 1999-12-13
SK284436B6 (sk) 2005-04-01
IL139529A (en) 2004-06-20
UA56315C2 (uk) 2003-05-15
CA2332054A1 (en) 1999-12-02
JP2002516332A (ja) 2002-06-04
PL191132B1 (pl) 2006-03-31
PT1082330E (pt) 2002-09-30
IL139529A0 (en) 2001-11-25
BR9910669B1 (pt) 2011-07-26
CZ162898A3 (cs) 1999-12-15
DE69901177T2 (de) 2002-10-02
EP1082330B1 (en) 2002-04-03
US6503943B1 (en) 2003-01-07
HRP20000791A2 (en) 2001-02-28
ES2175968T3 (es) 2002-11-16
HU224716B1 (en) 2006-01-30
CN1124279C (zh) 2003-10-15

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