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RU94046105A - АНАЛОГИ γ -АМИНОМАСЛЯНОЙ КИСЛОТЫ И L-ГЛУТАМИНОВОЙ КИСЛОТЫ И СПОСОБЫ ИХ ПОЛУЧЕНИЯ - Google Patents

АНАЛОГИ γ -АМИНОМАСЛЯНОЙ КИСЛОТЫ И L-ГЛУТАМИНОВОЙ КИСЛОТЫ И СПОСОБЫ ИХ ПОЛУЧЕНИЯ

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Publication number
RU94046105A
RU94046105A RU94046105/04A RU94046105A RU94046105A RU 94046105 A RU94046105 A RU 94046105A RU 94046105/04 A RU94046105/04 A RU 94046105/04A RU 94046105 A RU94046105 A RU 94046105A RU 94046105 A RU94046105 A RU 94046105A
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methods
acid
analogs
synthesis
glutamic acid
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RU94046105/04A
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English (en)
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Б.Силверман Ричард
Pl]
Йен По-Вай
Чарльз Фрэнклин Ллойд
Us]
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Нортвестерн Юниверсити (Us)
Нортвестерн Юниверсити
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Application filed by Нортвестерн Юниверсити (Us), Нортвестерн Юниверсити filed Critical Нортвестерн Юниверсити (Us)
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    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
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    • C07D263/16Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • A61P25/00Drugs for disorders of the nervous system
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    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/06Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
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    • C07C309/72Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
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    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18Oxygen atoms
    • C07D263/20Oxygen atoms attached in position 2
    • C07D263/22Oxygen atoms attached in position 2 with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to other ring carbon atoms

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Abstract

Соединения формулыгде R- нормальный или разветвленный С- С-алкил, фенил или С- С-циклоалкил; R- водород или метил; R- водород, метил или карбоксигруппа, применимы для лечения припадочных заболеваний. Предложены способы получения соединений. Также предложены полупродукты получения соединений формулы.

Claims (1)

  1. Соединения формулы
    Figure 00000001

    где R1 - нормальный или разветвленный С1 - С6-алкил, фенил или С3 - С6-циклоалкил; R2 - водород или метил; R3 - водород, метил или карбоксигруппа, применимы для лечения припадочных заболеваний. Предложены способы получения соединений. Также предложены полупродукты получения соединений формулы.
RU94046105/04A 1992-05-20 1993-05-18 АНАЛОГИ γ -АМИНОМАСЛЯНОЙ КИСЛОТЫ И L-ГЛУТАМИНОВОЙ КИСЛОТЫ И СПОСОБЫ ИХ ПОЛУЧЕНИЯ RU94046105A (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US88608092A 1992-05-20 1992-05-20
US886,080 1992-05-20

Publications (1)

Publication Number Publication Date
RU94046105A true RU94046105A (ru) 1997-06-20

Family

ID=25388336

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Application Number Title Priority Date Filing Date
RU94046105/04A RU94046105A (ru) 1992-05-20 1993-05-18 АНАЛОГИ γ -АМИНОМАСЛЯНОЙ КИСЛОТЫ И L-ГЛУТАМИНОВОЙ КИСЛОТЫ И СПОСОБЫ ИХ ПОЛУЧЕНИЯ
RU96124481A RU2140901C1 (ru) 1992-05-20 1993-05-18 АНАЛОГИ γ-АМИНОМАСЛЯНОЙ КИСЛОТЫ, СПОСОБ ИХ ПОЛУЧЕНИЯ, СПОСОБ ЛЕЧЕНИЯ И ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ

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HU222776B1 (hu) 2003-10-28
PT641330E (pt) 2002-03-28
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SG48288A1 (en) 1998-04-17
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