RU92016400A - Применение дифенилбутил-пиперазинкарбоксамидов при лечении токсикоманий - Google Patents
Применение дифенилбутил-пиперазинкарбоксамидов при лечении токсикоманийInfo
- Publication number
- RU92016400A RU92016400A RU92016400/14A RU92016400A RU92016400A RU 92016400 A RU92016400 A RU 92016400A RU 92016400/14 A RU92016400/14 A RU 92016400/14A RU 92016400 A RU92016400 A RU 92016400A RU 92016400 A RU92016400 A RU 92016400A
- Authority
- RU
- Russia
- Prior art keywords
- treatment
- diphenylbutyl
- piperazincarboxamides
- application
- toxic
- Prior art date
Links
- 230000002588 toxic Effects 0.000 title 1
- 231100000331 toxic Toxicity 0.000 title 1
- -1 (4-fluorophenyl) butyl-ethyl-1-piperazinecarboxamide Chemical compound 0.000 claims 1
- PTPTUSSTCDZDGG-UHFFFAOYSA-N 2-(4,4-diphenylbutyl)piperazine-1-carboxamide Chemical class NC(=O)N1CCNCC1CCCC(C=1C=CC=CC=1)C1=CC=CC=C1 PTPTUSSTCDZDGG-UHFFFAOYSA-N 0.000 claims 1
- 206010012335 Dependence Diseases 0.000 claims 1
- 206010013754 Drug withdrawal syndrome Diseases 0.000 claims 1
- 231100000614 Poison Toxicity 0.000 claims 1
- 230000003542 behavioural Effects 0.000 claims 1
- 235000019788 craving Nutrition 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 230000003533 narcotic Effects 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 239000011780 sodium chloride Substances 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
- 239000003440 toxic substance Substances 0.000 claims 1
Claims (1)
- Изобретение относится к применению некоторых дифенилбутил-пиперазинкарбоксамидов, в частности амперизида, 4- 4,4-бис(4-фторфенил) бутил-этил-1-пиперазинкарбоксамида и их солей при лечении нарушений, связанных с пристрастием к различным токсичным веществам. Кроме того лечение способствует облегчению симптомов отмены и изменения поведенческой реакции стремления к наркотическому веществу.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9100860A SE9100860D0 (sv) | 1991-03-22 | 1991-03-22 | New use |
| SE9100860-7 | 1991-03-22 | ||
| PCT/SE1992/000182 WO1992016211A1 (en) | 1991-03-22 | 1992-03-23 | New use of diphenylbutyl-piperazinecarboxamides in the treatment of substance disorders |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU92016400A true RU92016400A (ru) | 1995-02-10 |
| RU2095062C1 RU2095062C1 (ru) | 1997-11-10 |
Family
ID=20382242
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU9292016400A RU2095062C1 (ru) | 1991-03-22 | 1992-03-23 | Блокатор синдрома отмены, являющегося результатом привыкания к чрезмерному потреблению лекарств или веществ, вызывающих привыкание, фармакологическая композиция на его основе и способ облегчения или предотвращения синдрома отмены |
Country Status (24)
| Country | Link |
|---|---|
| US (2) | US5434156A (ru) |
| EP (1) | EP0538422B1 (ru) |
| JP (1) | JP3221611B2 (ru) |
| KR (1) | KR100196674B1 (ru) |
| AT (1) | ATE199057T1 (ru) |
| AU (1) | AU653797B2 (ru) |
| BG (1) | BG61829B1 (ru) |
| BR (1) | BR9204969A (ru) |
| CA (1) | CA2083505C (ru) |
| CZ (1) | CZ282222B6 (ru) |
| DE (1) | DE69231680T2 (ru) |
| DK (1) | DK0538422T3 (ru) |
| EE (1) | EE02973B1 (ru) |
| ES (1) | ES2154261T3 (ru) |
| GR (1) | GR3035805T3 (ru) |
| HU (2) | HU9203632D0 (ru) |
| IE (1) | IE920920A1 (ru) |
| NO (1) | NO301311B1 (ru) |
| PT (1) | PT100279B (ru) |
| RO (1) | RO109702B1 (ru) |
| RU (1) | RU2095062C1 (ru) |
| SE (1) | SE9100860D0 (ru) |
| SK (1) | SK279237B6 (ru) |
| WO (1) | WO1992016211A1 (ru) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9100860D0 (sv) * | 1991-03-22 | 1991-03-22 | Kabi Pharmacia Ab | New use |
| SE9201239D0 (sv) * | 1992-04-21 | 1992-04-21 | Kabi Pharmacia Ab | Agents for treating substance abuse disorders |
| JP3571114B2 (ja) * | 1995-07-11 | 2004-09-29 | ポーラ化成工業株式会社 | 麻薬拮抗剤 |
| US6265393B1 (en) | 1998-08-07 | 2001-07-24 | Heinrichs William Leroy | Prevention of endometriosis signs or symptons |
| US6090780A (en) * | 1999-04-07 | 2000-07-18 | Chandon Prasad | Histidyl-proline diketopiperazine and method of use |
| GB9923748D0 (en) | 1999-10-07 | 1999-12-08 | Glaxo Group Ltd | Chemical compounds |
| USRE39921E1 (en) | 1999-10-07 | 2007-11-13 | Smithkline Beecham Corporation | Chemical compounds |
| GB0025354D0 (en) | 2000-10-17 | 2000-11-29 | Glaxo Group Ltd | Chemical compounds |
| US20050192271A1 (en) * | 2003-07-15 | 2005-09-01 | Hythiam, Inc. | Use of selective chloride channel modulators to treat alcohol and/or stimulant substance abuse |
| CA2433833C (en) * | 2001-01-17 | 2009-06-02 | Juan Jose Legarda Ibanez | Use of flumazenil in developing a drug for the treatment of alcohol dependence |
| US7183410B2 (en) * | 2001-08-02 | 2007-02-27 | Bidachem S.P.A. | Stable polymorph of flibanserin |
| US20030060475A1 (en) * | 2001-08-10 | 2003-03-27 | Boehringer Ingelheim Pharma Kg | Method of using flibanserin for neuroprotection |
| UA78974C2 (en) * | 2001-10-20 | 2007-05-10 | Boehringer Ingelheim Pharma | Use of flibanserin for treating disorders of sexual desire |
| US10675280B2 (en) | 2001-10-20 | 2020-06-09 | Sprout Pharmaceuticals, Inc. | Treating sexual desire disorders with flibanserin |
| GB0203020D0 (en) | 2002-02-08 | 2002-03-27 | Glaxo Group Ltd | Chemical compounds |
| US7482365B2 (en) | 2002-02-08 | 2009-01-27 | Glaxo Group Limited | Piperidylcarboxamide derivatives and their use in the treatment of tachykinin-mediated diseases |
| GB0203022D0 (en) | 2002-02-08 | 2002-03-27 | Glaxo Group Ltd | Chemical compounds |
| US20050239798A1 (en) * | 2004-04-22 | 2005-10-27 | Boehringer Ingelheim Pharmaceuticals, Inc. | Method for the treatment of premenstrual and other female sexual disorders |
| RU2445095C2 (ru) * | 2004-04-22 | 2012-03-20 | Бёрингер Ингельхайм Интернациональ Гмбх | Новые фармацевтические композиции для лечения сексуальных расстройств |
| US20060025420A1 (en) * | 2004-07-30 | 2006-02-02 | Boehringer Ingelheimn International GmbH | Pharmaceutical compositions for the treatment of female sexual disorders |
| EP1789048A1 (en) * | 2004-09-03 | 2007-05-30 | Boehringer Ingelheim International GmbH | Method for the treatment of attention deficit hyperactivity disorder |
| EP1858516A1 (en) * | 2005-03-04 | 2007-11-28 | Boehringer Ingelheim International GmbH | Pharmaceutical compositions for the treatment and/or prevention of depression |
| WO2006096439A2 (en) * | 2005-03-04 | 2006-09-14 | Boehringer Ingelheim International Gmbh | Pharmaceutical compositions for the treatment and/or prevention of schizophrenia and related diseases |
| US20060199805A1 (en) * | 2005-03-04 | 2006-09-07 | Boehringer Ingelheim International Gmbh | Pharmaceutical compositions for the treatment and/or prevention of anxiety disorders |
| EP1904182A2 (en) * | 2005-05-06 | 2008-04-02 | Boehringer Ingelheim International GmbH | Method for the treatment of drug abuse with flibanserin |
| JP2008540673A (ja) * | 2005-05-19 | 2008-11-20 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 薬剤誘発性性機能不全の治療方法 |
| WO2006125041A1 (en) * | 2005-05-19 | 2006-11-23 | Boehringer Ingelheim International Gmbh | Method for the treatment of sexual dysfunctions due to medical conditions |
| WO2007014929A1 (en) | 2005-08-03 | 2007-02-08 | Boehringer Ingelheim International Gmbh | Use of flibanserin in the treatment of obesity |
| US20070123540A1 (en) * | 2005-10-29 | 2007-05-31 | Angelo Ceci | Sexual desire enhancing medicaments comprising benzimidazolone derivatives |
| EP1945214A1 (en) * | 2005-10-29 | 2008-07-23 | Boehringer Ingelheim International GmbH | Benzimidazolone derivatives for the treatment of premenstrual and other female sexual disorders |
| US20070105869A1 (en) * | 2005-11-08 | 2007-05-10 | Stephane Pollentier | Use of flibanserin for the treatment of pre-menopausal sexual desire disorders |
| AU2007247094B2 (en) * | 2006-05-09 | 2012-11-01 | Sprout Pharmaceuticals, Inc. | Use of flibanserin for the treatment of post-menopausal Sexual Desire Disorders |
| WO2008000760A1 (en) * | 2006-06-30 | 2008-01-03 | Boehringer Ingelheim International Gmbh | Flibanserin for the treatment of urinary incontinence and related diseases |
| CA2657043A1 (en) * | 2006-07-14 | 2008-01-17 | Boehringer Ingelheim International Gmbh | Use of flibanserin for the treatment of sexual disorders in females |
| CL2007002214A1 (es) * | 2006-08-14 | 2008-03-07 | Boehringer Ingelheim Int | Composicion farmaceutica en la forma de comprimido, donde al menos la longitud del comprimido en el estado anterior de la aplicacion es al menos 7/12 del diametro pilorico del paciente y despues de ingerirlo en estado alimentado, la longitud del comp |
| CA2660476C (en) | 2006-08-14 | 2015-11-17 | Boehringer Ingelheim International Gmbh | Formulations of flibanserin and method for manufacturing the same |
| BRPI0716436B8 (pt) * | 2006-08-25 | 2021-05-25 | Boehringer Ingelheim Int | sistema de liberação controlada e método para fabricação do mesmo |
| CL2008002693A1 (es) * | 2007-09-12 | 2009-10-16 | Boehringer Ingelheim Int | Uso de flibanserina para el tratamiento de sintomas vasomotores seleccionados de sofocos, sudores nocturnos, cambios de estado de animo e irritabilidad |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NO154582C (no) * | 1978-10-20 | 1986-11-05 | Ferrosan Ab | Analogifremgangsmaate for fremstilling av terapeutisk aktive difenyl-dibutylpiperazinkarboksamider. |
| SE9100860D0 (sv) * | 1991-03-22 | 1991-03-22 | Kabi Pharmacia Ab | New use |
-
1991
- 1991-03-22 SE SE9100860A patent/SE9100860D0/xx unknown
-
1992
- 1992-03-23 DK DK92907159T patent/DK0538422T3/da active
- 1992-03-23 ES ES92907159T patent/ES2154261T3/es not_active Expired - Lifetime
- 1992-03-23 EP EP92907159A patent/EP0538422B1/en not_active Expired - Lifetime
- 1992-03-23 RU RU9292016400A patent/RU2095062C1/ru not_active IP Right Cessation
- 1992-03-23 HU HU9203632A patent/HU9203632D0/hu unknown
- 1992-03-23 AU AU14280/92A patent/AU653797B2/en not_active Ceased
- 1992-03-23 HU HU9203632A patent/HU217833B/hu not_active IP Right Cessation
- 1992-03-23 SK SK3449-92A patent/SK279237B6/sk unknown
- 1992-03-23 US US07/949,869 patent/US5434156A/en not_active Expired - Fee Related
- 1992-03-23 BR BR9204969A patent/BR9204969A/pt not_active Application Discontinuation
- 1992-03-23 IE IE092092A patent/IE920920A1/en not_active IP Right Cessation
- 1992-03-23 JP JP50658392A patent/JP3221611B2/ja not_active Expired - Fee Related
- 1992-03-23 CA CA002083505A patent/CA2083505C/en not_active Expired - Fee Related
- 1992-03-23 DE DE69231680T patent/DE69231680T2/de not_active Expired - Fee Related
- 1992-03-23 PT PT100279A patent/PT100279B/pt not_active IP Right Cessation
- 1992-03-23 RO RO92-01457A patent/RO109702B1/ro unknown
- 1992-03-23 KR KR1019920702939A patent/KR100196674B1/ko not_active IP Right Cessation
- 1992-03-23 CZ CS923449A patent/CZ282222B6/cs not_active IP Right Cessation
- 1992-03-23 AT AT92907159T patent/ATE199057T1/de not_active IP Right Cessation
- 1992-03-23 WO PCT/SE1992/000182 patent/WO1992016211A1/en active IP Right Grant
- 1992-11-20 BG BG97108A patent/BG61829B1/bg unknown
- 1992-11-23 NO NO924502A patent/NO301311B1/no unknown
-
1994
- 1994-11-17 EE EE9400358A patent/EE02973B1/xx not_active IP Right Cessation
-
1995
- 1995-04-25 US US08/428,899 patent/US5618817A/en not_active Expired - Fee Related
-
2001
- 2001-04-27 GR GR20010400653T patent/GR3035805T3/el not_active IP Right Cessation
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