PT1517883E - Derivados do ácido benzóico substituído na posição orto para o tratamento de resistência à insulina - Google Patents

Derivados do ácido benzóico substituído na posição orto para o tratamento de resistência à insulina Download PDF

Info

Publication number: PT1517883E
Authority: PT; Portugal
Prior art keywords: ortho; treatment; benzoic acid; acid derivatives; insulin resistance
Prior art date: 2002-06-20

Application number

PT03732713T

Other languages

English (en)

Inventor

Lanna Li

Original Assignee

Astrazeneca Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-06-20

Filing date

2003-06-17

Publication date

2008-04-21

2002-06-20 Priority claimed from SE0201935A external-priority patent/SE0201935D0/xx

2002-12-20 Priority claimed from SE0203826A external-priority patent/SE0203826D0/xx

2003-06-17 Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab

2008-04-21 Publication of PT1517883E publication Critical patent/PT1517883E/pt

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/32—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C07C235/34—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/62—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Diabetes (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Obesity (AREA)
Hematology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Endocrinology (AREA)
Emergency Medicine (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Child & Adolescent Psychology (AREA)
Epidemiology (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Peptides Or Proteins (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Steroid Compounds (AREA)

PT03732713T 2002-06-20 2003-06-17 Derivados do ácido benzóico substituído na posição orto para o tratamento de resistência à insulina PT1517883E (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
SE0201935A SE0201935D0 (sv)	2002-06-20	2002-06-20	Therapeutic agents
SE0203826A SE0203826D0 (sv)	2002-12-20	2002-12-20	Therapeutic agents

Publications (1)

Publication Number	Publication Date
PT1517883E true PT1517883E (pt)	2008-04-21

Family

ID=30002442

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT03732713T PT1517883E (pt)	2002-06-20	2003-06-17	Derivados do ácido benzóico substituído na posição orto para o tratamento de resistência à insulina

Country Status (22)

Country	Link
US (1)	US7355069B2 (pt)
EP (1)	EP1517883B8 (pt)
JP (2)	JP3782818B2 (pt)
KR (1)	KR20050014013A (pt)
CN (1)	CN1319938C (pt)
AR (1)	AR039713A1 (pt)
AT (1)	ATE386013T1 (pt)
AU (1)	AU2003240099B2 (pt)
BR (1)	BR0311932A (pt)
CA (1)	CA2489834C (pt)
DE (1)	DE60319084T2 (pt)
DK (1)	DK1517883T3 (pt)
ES (1)	ES2299702T3 (pt)
IL (1)	IL165671A0 (pt)
IS (1)	IS7627A (pt)
MX (1)	MXPA04012686A (pt)
NO (1)	NO20045353L (pt)
PL (1)	PL375074A1 (pt)
PT (1)	PT1517883E (pt)
RU (1)	RU2004137094A (pt)
TW (1)	TWI282784B (pt)
WO (1)	WO2004000790A1 (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6262118B1 (en) *	1999-06-04	2001-07-17	Metabolex, Inc.	Use of (-) (3-trihalomethylphenoxy) (4-halophenyl) acetic acid derivatives for treatment of insulin resistance, type 2 diabetes and hyperlipidemia
US7576131B2 (en)	1999-06-04	2009-08-18	Metabolex, Inc.	Use of (-) (3-trihalomethylphenoxy) (4-halophenyl) acetic acid derivatives for treatment of insulin resistance, type 2 diabetes, hyperlipidemia and hyperuricemia
SE0104333D0 (sv)	2001-12-19	2001-12-19	Astrazeneca Ab	Therapeutic agents
FR2875805B1 (fr) *	2004-09-27	2006-12-29	Genfit S A	Composes derives de n-(benzyl) phenylacetamide substitues, preparation et utilisations
GB0522431D0 (en) *	2005-11-03	2005-12-14	Astrazeneca Ab	Chemical process
GB0522433D0 (en) *	2005-11-03	2005-12-14	Astrazeneca Ab	Therapeutic agents

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK148576A (da)	1975-04-18	1976-10-19	Boehringer Mannheim Gmbh	Fenylalkankarbonsyrederivater og fremgangsmade til deres fremstilling
DE19615263A1 (de)	1996-04-18	1997-10-23	Bayer Ag	Benzyloxy-substituierte Phenylglycinolamide
BR9814087A (pt)	1997-10-17	2000-10-03	Aventis Pharm Prod Inc	Processos para mediar a atividade do receptor de ppar-gama, e para tratar uma condição fisiológica em um paciente
PL341044A1 (en)	1997-12-19	2001-03-26	Schering Ag	Derivatives of orthoantranilic amide as anticoagulants
SE9801992D0 (sv)	1998-06-04	1998-06-04	Astra Ab	New 3-aryl-2-hydroxypropionic acid derivative I
GB9822473D0 (en)	1998-10-16	1998-12-09	Glaxo Group Ltd	Chemical compounds
YU74701A (sh)	1999-04-28	2005-07-19	Aventis Pharma Deutschland Gmbh.	Derivati tri-aril kiseline kao ligandi ppar receptora
HRP20010795A2 (en)	1999-04-28	2003-02-28	Aventis Pharma Gmbh	Di-aryl acid derivatives as ppar receptor ligands
JP4618845B2 (ja) *	1999-06-09	2011-01-26	杏林製薬株式会社	ヒトペルオキシゾーム増殖薬活性化受容体（ＰＰＡＲ）αアゴニストとしての置換フェニルプロピオン酸誘導体
GB9919411D0 (en)	1999-08-18	1999-10-20	Zeneca Ltd	Chemical compounds
SE0000772D0 (sv)	2000-03-08	2000-03-08	Astrazeneca Ab	Chemical compounds
US6509374B2 (en)	2000-04-17	2003-01-21	Novo Nordisk A/S	Compounds, their preparation and use
SE0003766D0 (sv)	2000-10-18	2000-10-18	Astrazeneca Ab	Novel formulation
EG26979A (en)	2000-12-21	2015-03-01	Astrazeneca Ab	Chemical compounds
GB0116955D0 (en)	2001-07-11	2001-09-05	Syngenta Ltd	Weed control process
GB0121337D0 (en)	2001-09-04	2001-10-24	Astrazeneca Ab	Chemical compounds
GB0121621D0 (en)	2001-09-07	2001-10-31	Astrazeneca Ab	Chemical compounds
GB0121622D0 (en)	2001-09-07	2001-10-31	Astrazeneca Ab	Chemical compounds
US7132416B2 (en)	2001-09-08	2006-11-07	Astrazeneca Ab	Benzothiazepine and benzothiazepine derivatives with ileal bile acid transport (IBAT) inhibotory activity for the treatment hyperlipidaemia
SE0104334D0 (sv)	2001-12-19	2001-12-19	Astrazeneca Ab	Therapeutic agents
GB0229931D0 (en)	2002-12-21	2003-01-29	Astrazeneca Ab	Therapeutic agents
SE0104333D0 (sv)	2001-12-19	2001-12-19	Astrazeneca Ab	Therapeutic agents
GB0209467D0 (en)	2002-04-25	2002-06-05	Astrazeneca Ab	Chemical compounds
GB0213669D0 (en)	2002-06-14	2002-07-24	Astrazeneca Ab	Chemical compounds
US7351858B2 (en)	2002-06-20	2008-04-01	Astrazeneca Ab	Ortho-substituted benzoic acid derivatives for the treatment of insulin resistance
SE0201936D0 (sv)	2002-06-20	2002-06-20	Astrazeneca Ab	Therapeutic agents
SE0201937D0 (sv)	2002-06-20	2002-06-20	Astrazeneca Ab	Therapeutic agents
GB0314075D0 (en)	2003-06-18	2003-07-23	Astrazeneca Ab	Therapeutic agents
GB0314078D0 (en)	2003-06-18	2003-07-23	Astrazeneca Ab	Therapeutic agents
GB0314130D0 (en)	2003-06-18	2003-07-23	Astrazeneca Ab	Therapeutic agents
GB0314129D0 (en)	2003-06-18	2003-07-23	Astrazeneca Ab	Therapeutic agents
GB0314131D0 (en)	2003-06-18	2003-07-23	Astrazeneca Ab	Therapeutic agents
GB0314136D0 (en)	2003-06-18	2003-07-23	Astrazeneca Ab	Therapeutic agents
GB0314260D0 (en)	2003-06-19	2003-07-23	Astrazeneca Ab	Therapeutic agents

2003
- 2003-06-17 EP EP03732713A patent/EP1517883B8/en not_active Expired - Lifetime
- 2003-06-17 TW TW092116378A patent/TWI282784B/zh not_active IP Right Cessation
- 2003-06-17 JP JP2004515007A patent/JP3782818B2/ja not_active Expired - Lifetime
- 2003-06-17 KR KR10-2004-7020670A patent/KR20050014013A/ko not_active Withdrawn
- 2003-06-17 CN CNB038194740A patent/CN1319938C/zh not_active Expired - Fee Related
- 2003-06-17 US US10/518,007 patent/US7355069B2/en not_active Expired - Fee Related
- 2003-06-17 AT AT03732713T patent/ATE386013T1/de not_active IP Right Cessation
- 2003-06-17 ES ES03732713T patent/ES2299702T3/es not_active Expired - Lifetime
- 2003-06-17 AU AU2003240099A patent/AU2003240099B2/en not_active Ceased
- 2003-06-17 RU RU2004137094/04A patent/RU2004137094A/ru not_active Application Discontinuation
- 2003-06-17 WO PCT/GB2003/002584 patent/WO2004000790A1/en active IP Right Grant
- 2003-06-17 DE DE60319084T patent/DE60319084T2/de not_active Expired - Lifetime
- 2003-06-17 PT PT03732713T patent/PT1517883E/pt unknown
- 2003-06-17 PL PL03375074A patent/PL375074A1/xx not_active Application Discontinuation
- 2003-06-17 BR BR0311932-7A patent/BR0311932A/pt not_active IP Right Cessation
- 2003-06-17 MX MXPA04012686A patent/MXPA04012686A/es not_active Application Discontinuation
- 2003-06-17 DK DK03732713T patent/DK1517883T3/da active
- 2003-06-17 CA CA002489834A patent/CA2489834C/en not_active Expired - Fee Related
- 2003-06-20 AR ARP030102197A patent/AR039713A1/es not_active Application Discontinuation
2004
- 2004-12-07 NO NO20045353A patent/NO20045353L/no not_active Application Discontinuation
- 2004-12-09 IL IL16567104A patent/IL165671A0/xx unknown
2005
- 2005-01-05 IS IS7627A patent/IS7627A/is unknown
2006
- 2006-01-27 JP JP2006019068A patent/JP2006182782A/ja active Pending

Also Published As

Publication number	Publication date
CA2489834C (en)	2006-10-03
ATE386013T1 (de)	2008-03-15
DE60319084D1 (de)	2008-03-27
KR20050014013A (ko)	2005-02-05
AU2003240099B2 (en)	2007-02-01
TW200409747A (en)	2004-06-16
DK1517883T3 (da)	2008-05-26
WO2004000790A1 (en)	2003-12-31
JP3782818B2 (ja)	2006-06-07
CN1319938C (zh)	2007-06-06
ES2299702T3 (es)	2008-06-01
AU2003240099A1 (en)	2004-01-06
TWI282784B (en)	2007-06-21
JP2005529970A (ja)	2005-10-06
IS7627A (is)	2005-01-05
NO20045353L (no)	2005-01-20
RU2004137094A (ru)	2005-08-10
EP1517883B8 (en)	2008-05-21
US7355069B2 (en)	2008-04-08
CA2489834A1 (en)	2003-12-31
MXPA04012686A (es)	2005-03-23
IL165671A0 (en)	2006-01-15
HK1073838A1 (en)	2005-10-21
DE60319084T2 (de)	2009-01-29
EP1517883B1 (en)	2008-02-13
BR0311932A (pt)	2005-03-22
CN1675171A (zh)	2005-09-28
AR039713A1 (es)	2005-03-09
PL375074A1 (en)	2005-11-14
US20050256198A1 (en)	2005-11-17
EP1517883A1 (en)	2005-03-30
JP2006182782A (ja)	2006-07-13

Publication	Publication Date	Title
IL147822A0 (en)	2002-08-14	Benzoic acid derivatives for the treatment of diabetes mellitus
PL372865A1 (en)	2005-08-08	Aryl 5-thio-beta-d-glucopyranoside derivatives and remedies for diabetes containing the same
IL173522A0 (en)	2006-07-05	Phenoxyacetic acid derivatives
AU2003299741A8 (en)	2004-07-22	Steerable catheter
IL177232A0 (en)	2006-12-10	Heteroarylaminopyrazole derivatives useful for the treatment of diabetes
AU2003265382A8 (en)	2004-03-11	Antibacterial benzoic acid derivatives
PL377164A1 (pl)	2006-01-23	Pochodne anilinopirazolu przydatne do leczenia cukrzycy
AU2003279442A8 (en)	2004-04-23	2-thiohydantoine derivative compounds and use thereof for the treatment of diabetes
EP1535644A4 (en)	2006-05-17	NEEDLE FOR MEDICAL USE
IL165242A0 (en)	2005-12-18	Treatment for diabetes
PL375074A1 (en)	2005-11-14	Ortho-substituted benzoic acid derivatives for the treatment of insulin resistance
PT1517679E (pt)	2008-04-21	Derivados do ácido benzóico substituído na posição orto para o tratamento de resistência à insulina
EP1750698A4 (en)	2010-06-02	5-ANILINO-4-HETEROARYLPYRAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF DIABETES
ZA200605302B (en)	2007-04-25	Use of pentadienoic acid derivatives for the treatment of hyperuricemia
SI1517883T1 (sl)	2008-06-30	Orto-substituirani derivati benzojske kisline za zdravljenje insulinske rezistence
SI1517679T1 (sl)	2008-06-30	Orto-substituirani derivati benzojske kisline za zdravljenje insulinske rezistence
AU2002335304A1 (en)	2004-05-04	The use of berberine as insulin sensitizer
GB0315878D0 (en)	2003-08-13	Aryl carboxylic acid derivatives and their therapeutic use
GB0212790D0 (en)	2002-07-10	Medicament for the treatment of diabetes
EP1177789A3 (en)	2003-01-29	Use of phytanic acid for the treatment of diabetes
ZA200608015B (en)	2008-12-31	Heteroarylaminopyrazole derivatives useful for the treatment of diabetes
GB0326306D0 (en)	2003-12-17	Heat sensitive composition comprising benzoic acid derivatives
GB0315876D0 (en)	2003-08-13	Aryl and heteroaryl carboxylic acid derivatives and their therapeutic use
GB0219252D0 (en)	2002-09-25	Patient monitoring
GB0211098D0 (en)	2002-06-26	Medical compounds