DK1517883T3 - Ortho-substituerede benzoesyrederivater til behandling af insulinresistens - Google Patents

Ortho-substituerede benzoesyrederivater til behandling af insulinresistens

Info

Publication number: DK1517883T3
Authority: DK; Denmark
Prior art keywords: ortho; treatment; benzoic acid; acid derivatives; insulin resistance
Prior art date: 2002-06-20

Application number

DK03732713T

Other languages

English (en)

Inventor

Lanna Li

Original Assignee

Astrazeneca Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-06-20

Filing date

2003-06-17

Publication date

2008-05-26

2002-06-20 Priority claimed from SE0201935A external-priority patent/SE0201935D0/xx

2002-12-20 Priority claimed from SE0203826A external-priority patent/SE0203826D0/xx

2003-06-17 Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab

2008-05-26 Application granted granted Critical

2008-05-26 Publication of DK1517883T3 publication Critical patent/DK1517883T3/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/32—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C07C235/34—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/62—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Diabetes (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Obesity (AREA)
Hematology (AREA)
Heart & Thoracic Surgery (AREA)
Endocrinology (AREA)
Cardiology (AREA)
Child & Adolescent Psychology (AREA)
Emergency Medicine (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Epidemiology (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Peptides Or Proteins (AREA)
Steroid Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

DK03732713T 2002-06-20 2003-06-17 Ortho-substituerede benzoesyrederivater til behandling af insulinresistens DK1517883T3 (da)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
SE0201935A SE0201935D0 (sv)	2002-06-20	2002-06-20	Therapeutic agents
SE0203826A SE0203826D0 (sv)	2002-12-20	2002-12-20	Therapeutic agents
PCT/GB2003/002584 WO2004000790A1 (en)	2002-06-20	2003-06-17	Ortho-substituted benzoic acid derivatives for the treatment of insulin resistance

Publications (1)

Publication Number	Publication Date
DK1517883T3 true DK1517883T3 (da)	2008-05-26

Family

ID=30002442

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK03732713T DK1517883T3 (da)	2002-06-20	2003-06-17	Ortho-substituerede benzoesyrederivater til behandling af insulinresistens

Country Status (23)

Country	Link
US (1)	US7355069B2 (da)
EP (1)	EP1517883B8 (da)
JP (2)	JP3782818B2 (da)
KR (1)	KR20050014013A (da)
CN (1)	CN1319938C (da)
AR (1)	AR039713A1 (da)
AT (1)	ATE386013T1 (da)
AU (1)	AU2003240099B2 (da)
BR (1)	BR0311932A (da)
CA (1)	CA2489834C (da)
DE (1)	DE60319084T2 (da)
DK (1)	DK1517883T3 (da)
ES (1)	ES2299702T3 (da)
HK (1)	HK1073838A1 (da)
IL (1)	IL165671A0 (da)
IS (1)	IS7627A (da)
MX (1)	MXPA04012686A (da)
NO (1)	NO20045353L (da)
PL (1)	PL375074A1 (da)
PT (1)	PT1517883E (da)
RU (1)	RU2004137094A (da)
TW (1)	TWI282784B (da)
WO (1)	WO2004000790A1 (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7576131B2 (en)	1999-06-04	2009-08-18	Metabolex, Inc.	Use of (-) (3-trihalomethylphenoxy) (4-halophenyl) acetic acid derivatives for treatment of insulin resistance, type 2 diabetes, hyperlipidemia and hyperuricemia
US6262118B1 (en) *	1999-06-04	2001-07-17	Metabolex, Inc.	Use of (-) (3-trihalomethylphenoxy) (4-halophenyl) acetic acid derivatives for treatment of insulin resistance, type 2 diabetes and hyperlipidemia
SE0104333D0 (sv)	2001-12-19	2001-12-19	Astrazeneca Ab	Therapeutic agents
FR2875805B1 (fr) *	2004-09-27	2006-12-29	Genfit S A	Composes derives de n-(benzyl) phenylacetamide substitues, preparation et utilisations
GB0522431D0 (en) *	2005-11-03	2005-12-14	Astrazeneca Ab	Chemical process
GB0522433D0 (en) *	2005-11-03	2005-12-14	Astrazeneca Ab	Therapeutic agents

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK148576A (da)	1975-04-18	1976-10-19	Boehringer Mannheim Gmbh	Fenylalkankarbonsyrederivater og fremgangsmade til deres fremstilling
DE19615263A1 (de) *	1996-04-18	1997-10-23	Bayer Ag	Benzyloxy-substituierte Phenylglycinolamide
CA2306825A1 (en)	1997-10-17	1999-04-29	Avantis Pharmaceuticals Products Inc.	Therapeutic uses of quinoline derivatives
PT1040108E (pt)	1997-12-19	2004-06-30	Schering Ag	Derivados de orto-antranilamida como anticoagulantes
SE9801992D0 (sv)	1998-06-04	1998-06-04	Astra Ab	New 3-aryl-2-hydroxypropionic acid derivative I
GB9822473D0 (en)	1998-10-16	1998-12-09	Glaxo Group Ltd	Chemical compounds
SK15522001A3 (sk)	1999-04-28	2002-06-04	Aventis Pharma Deutschland Gmbh	Deriváty kyselín s tromi arylovými zvyškami ako ligandy receptorov PPAR a farmaceutické kompozície, ktoré ich obsahujú
NZ515086A (en)	1999-04-28	2003-10-31	Aventis Pharma Gmbh	Di-aryl acid derivatives as PPAR receptor ligands
JP4618845B2 (ja)	1999-06-09	2011-01-26	杏林製薬株式会社	ヒトペルオキシゾーム増殖薬活性化受容体（ＰＰＡＲ）αアゴニストとしての置換フェニルプロピオン酸誘導体
GB9919411D0 (en)	1999-08-18	1999-10-20	Zeneca Ltd	Chemical compounds
SE0000772D0 (sv)	2000-03-08	2000-03-08	Astrazeneca Ab	Chemical compounds
US6509374B2 (en)	2000-04-17	2003-01-21	Novo Nordisk A/S	Compounds, their preparation and use
SE0003766D0 (sv)	2000-10-18	2000-10-18	Astrazeneca Ab	Novel formulation
EG26979A (en)	2000-12-21	2015-03-01	Astrazeneca Ab	Chemical compounds
GB0116955D0 (en)	2001-07-11	2001-09-05	Syngenta Ltd	Weed control process
GB0121337D0 (en)	2001-09-04	2001-10-24	Astrazeneca Ab	Chemical compounds
GB0121622D0 (en)	2001-09-07	2001-10-31	Astrazeneca Ab	Chemical compounds
GB0121621D0 (en)	2001-09-07	2001-10-31	Astrazeneca Ab	Chemical compounds
JP3616635B2 (ja)	2001-09-08	2005-02-02	アストラゼネカアクチボラグ	高脂質血症の治療のための回腸胆汁酸運搬（ｉｂａｔ）阻害活性を持つベンゾチアゼピン及びベンゾチアジアゼピン誘導体
GB0229931D0 (en)	2002-12-21	2003-01-29	Astrazeneca Ab	Therapeutic agents
SE0104334D0 (sv)	2001-12-19	2001-12-19	Astrazeneca Ab	Therapeutic agents
SE0104333D0 (sv)	2001-12-19	2001-12-19	Astrazeneca Ab	Therapeutic agents
GB0209467D0 (en)	2002-04-25	2002-06-05	Astrazeneca Ab	Chemical compounds
GB0213669D0 (en)	2002-06-14	2002-07-24	Astrazeneca Ab	Chemical compounds
SE0201937D0 (sv)	2002-06-20	2002-06-20	Astrazeneca Ab	Therapeutic agents
SE0201936D0 (sv)	2002-06-20	2002-06-20	Astrazeneca Ab	Therapeutic agents
US7351858B2 (en)	2002-06-20	2008-04-01	Astrazeneca Ab	Ortho-substituted benzoic acid derivatives for the treatment of insulin resistance
GB0314130D0 (en)	2003-06-18	2003-07-23	Astrazeneca Ab	Therapeutic agents
GB0314078D0 (en)	2003-06-18	2003-07-23	Astrazeneca Ab	Therapeutic agents
GB0314136D0 (en)	2003-06-18	2003-07-23	Astrazeneca Ab	Therapeutic agents
GB0314075D0 (en)	2003-06-18	2003-07-23	Astrazeneca Ab	Therapeutic agents
GB0314129D0 (en)	2003-06-18	2003-07-23	Astrazeneca Ab	Therapeutic agents
GB0314131D0 (en)	2003-06-18	2003-07-23	Astrazeneca Ab	Therapeutic agents
GB0314260D0 (en)	2003-06-19	2003-07-23	Astrazeneca Ab	Therapeutic agents

2003
- 2003-06-17 RU RU2004137094/04A patent/RU2004137094A/ru not_active Application Discontinuation
- 2003-06-17 EP EP03732713A patent/EP1517883B8/en not_active Expired - Lifetime
- 2003-06-17 AT AT03732713T patent/ATE386013T1/de not_active IP Right Cessation
- 2003-06-17 PL PL03375074A patent/PL375074A1/xx not_active Application Discontinuation
- 2003-06-17 ES ES03732713T patent/ES2299702T3/es not_active Expired - Lifetime
- 2003-06-17 CA CA002489834A patent/CA2489834C/en not_active Expired - Fee Related
- 2003-06-17 TW TW092116378A patent/TWI282784B/zh not_active IP Right Cessation
- 2003-06-17 DK DK03732713T patent/DK1517883T3/da active
- 2003-06-17 BR BR0311932-7A patent/BR0311932A/pt not_active IP Right Cessation
- 2003-06-17 PT PT03732713T patent/PT1517883E/pt unknown
- 2003-06-17 CN CNB038194740A patent/CN1319938C/zh not_active Expired - Fee Related
- 2003-06-17 US US10/518,007 patent/US7355069B2/en not_active Expired - Fee Related
- 2003-06-17 KR KR10-2004-7020670A patent/KR20050014013A/ko not_active Application Discontinuation
- 2003-06-17 WO PCT/GB2003/002584 patent/WO2004000790A1/en active IP Right Grant
- 2003-06-17 JP JP2004515007A patent/JP3782818B2/ja not_active Expired - Lifetime
- 2003-06-17 DE DE60319084T patent/DE60319084T2/de not_active Expired - Lifetime
- 2003-06-17 MX MXPA04012686A patent/MXPA04012686A/es not_active Application Discontinuation
- 2003-06-17 AU AU2003240099A patent/AU2003240099B2/en not_active Ceased
- 2003-06-20 AR ARP030102197A patent/AR039713A1/es not_active Application Discontinuation
2004
- 2004-12-07 NO NO20045353A patent/NO20045353L/no not_active Application Discontinuation
- 2004-12-09 IL IL16567104A patent/IL165671A0/xx unknown
2005
- 2005-01-05 IS IS7627A patent/IS7627A/is unknown
- 2005-07-26 HK HK05106401A patent/HK1073838A1/xx not_active IP Right Cessation
2006
- 2006-01-27 JP JP2006019068A patent/JP2006182782A/ja active Pending

Also Published As

Publication number	Publication date
JP2006182782A (ja)	2006-07-13
CN1319938C (zh)	2007-06-06
EP1517883A1 (en)	2005-03-30
DE60319084D1 (de)	2008-03-27
RU2004137094A (ru)	2005-08-10
JP2005529970A (ja)	2005-10-06
NO20045353L (no)	2005-01-20
TWI282784B (en)	2007-06-21
BR0311932A (pt)	2005-03-22
EP1517883B1 (en)	2008-02-13
EP1517883B8 (en)	2008-05-21
CN1675171A (zh)	2005-09-28
CA2489834C (en)	2006-10-03
DE60319084T2 (de)	2009-01-29
US20050256198A1 (en)	2005-11-17
JP3782818B2 (ja)	2006-06-07
AR039713A1 (es)	2005-03-09
AU2003240099A1 (en)	2004-01-06
IS7627A (is)	2005-01-05
HK1073838A1 (en)	2005-10-21
WO2004000790A1 (en)	2003-12-31
AU2003240099B2 (en)	2007-02-01
KR20050014013A (ko)	2005-02-05
PT1517883E (pt)	2008-04-21
PL375074A1 (en)	2005-11-14
ATE386013T1 (de)	2008-03-15
ES2299702T3 (es)	2008-06-01
TW200409747A (en)	2004-06-16
CA2489834A1 (en)	2003-12-31
IL165671A0 (en)	2006-01-15
US7355069B2 (en)	2008-04-08
MXPA04012686A (es)	2005-03-23

Publication	Publication Date	Title
CY2013027I1 (el)	2024-09-20	Νεα παραγωγα ινσουλινης
DK1660431T3 (da)	2009-06-15	Phenoxyeddikesyrederivater
DK1542748T3 (da)	2014-05-12	Engangssprøjte
DK1471057T3 (da)	2006-05-15	Pyrimidinyleddikesyrederivater, der er egnede til behandlingen af sygdomme medieret af CRTH2
DK1803718T3 (da)	2008-10-27	4-Tetrazolyl-4-phenylpiperidin-derivater til behandling af smerter
IS8941A (is)	2010-12-29	Efnasambönd með bólgueyðandi virkni
DK2275439T3 (da)	2014-05-12	Hidtil ukendte insulinderivater
DK1487828T3 (da)	2009-02-02	Morpholinyl-urea-derivater til anvendelse til behandling af inflammatoriske sygdomme
DK1517883T3 (da)	2008-05-26	Ortho-substituerede benzoesyrederivater til behandling af insulinresistens
DK1434588T3 (da)	2011-08-15	2-(amino-3,4-dioxo-1cyclobuten-1-yl)aminoalkylsyrederivater til behandling af smerte
DK1517679T3 (da)	2008-05-19	Ortosubstituerede benzoesyrederivater til behandling af insulinresistens
DE60324703D1 (de)	2008-12-24	Barbitursäure derivaten.
FI20021783A0 (fi)	2002-10-07	Menetelmä kardiovaskulaaristen sairauksien riskin havaitsemiseksi
DK1620085T3 (da)	2008-11-24	Anvendelse af phenoxyacetatsyrederivater til behandling af hyperaktiv blære
DK1497290T3 (da)	2008-12-15	Fremgangsmåde til fremstilling af syresalte af gemifloxacin
DK1593391T3 (da)	2013-11-11	Lægemiddel til degenererede båndskiver
SI1517883T1 (sl)	2008-06-30	Orto-substituirani derivati benzojske kisline za zdravljenje insulinske rezistence
SI1517679T1 (sl)	2008-06-30	Orto-substituirani derivati benzojske kisline za zdravljenje insulinske rezistence
ES1051002Y (es)	2002-10-16	Jeringa perfeccionada.
ES1055675Y (es)	2004-04-16	Jeringa perfeccionada.
FI20021817A0 (fi)	2002-10-14	Kanyyli
IS8301A (is)	2006-02-14	Nýjar fúsíðsýruafleiður
UA6623S (uk)	2002-11-15	Шприц
ITVI20020014A1 (it)	2003-07-29	Siringa monouso
UA6774S (uk)	2002-12-16	Натільна пов`язка для суглобів