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PT1175224E - Terapeutica de combinacao contra hiv com interferao-alfa peguilado e um antagonista de ccr5 - Google Patents

Terapeutica de combinacao contra hiv com interferao-alfa peguilado e um antagonista de ccr5

Info

Publication number
PT1175224E
PT1175224E PT00928604T PT00928604T PT1175224E PT 1175224 E PT1175224 E PT 1175224E PT 00928604 T PT00928604 T PT 00928604T PT 00928604 T PT00928604 T PT 00928604T PT 1175224 E PT1175224 E PT 1175224E
Authority
PT
Portugal
Prior art keywords
peguiled
interphant
alpha
combination therapy
ccr5 antagonist
Prior art date
Application number
PT00928604T
Other languages
English (en)
Inventor
Mark A Laughlin
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of PT1175224E publication Critical patent/PT1175224E/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A61K38/212—IFN-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Virology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
PT00928604T 1999-05-04 2000-05-01 Terapeutica de combinacao contra hiv com interferao-alfa peguilado e um antagonista de ccr5 PT1175224E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US30489799A 1999-05-04 1999-05-04

Publications (1)

Publication Number Publication Date
PT1175224E true PT1175224E (pt) 2005-07-29

Family

ID=23178462

Family Applications (1)

Application Number Title Priority Date Filing Date
PT00928604T PT1175224E (pt) 1999-05-04 2000-05-01 Terapeutica de combinacao contra hiv com interferao-alfa peguilado e um antagonista de ccr5

Country Status (21)

Country Link
EP (1) EP1175224B1 (pt)
JP (1) JP2002543144A (pt)
CN (1) CN1349408A (pt)
AR (1) AR023824A1 (pt)
AT (1) ATE289516T1 (pt)
AU (1) AU776541B2 (pt)
BR (1) BR0010593A (pt)
CA (1) CA2365900A1 (pt)
DE (1) DE60018273T2 (pt)
ES (1) ES2238277T3 (pt)
HK (1) HK1039278B (pt)
HU (1) HUP0202734A3 (pt)
MX (1) MXPA01011116A (pt)
MY (1) MY127670A (pt)
NO (1) NO328679B1 (pt)
NZ (1) NZ514519A (pt)
PE (1) PE20010283A1 (pt)
PT (1) PT1175224E (pt)
TW (1) TWI289454B (pt)
WO (1) WO2000066141A2 (pt)
ZA (1) ZA200108870B (pt)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050065319A1 (en) * 2000-12-19 2005-03-24 Baroudy Bahige M. Combination method for treating viral infections
NZ542304A (en) 2003-03-14 2009-07-31 Ono Pharmaceutical Co Nitrogen-containing heterocyclic derivatives and drugs containing the same as the active ingredient
JP4710606B2 (ja) 2003-04-18 2011-06-29 小野薬品工業株式会社 スピロピペリジン化合物およびその医薬用途
WO2004092136A1 (ja) * 2003-04-18 2004-10-28 Ono Pharmaceutical Co., Ltd. 含窒素複素環化合物およびその用途
ATE374838T1 (de) 2004-04-29 2007-10-15 Hoffmann La Roche Nukleotidsequenzvariation im gen ns5a als marker
TWI400232B (zh) 2004-09-13 2013-07-01 Ono Pharmaceutical Co 含氮雜環衍生物及以該含氮雜環衍生物為有效成分之藥劑
AU2006216731A1 (en) * 2005-02-23 2006-08-31 Schering Corporation Piperidinyl piperazine derivatives useful as inhibitors of chemokine receptors
WO2006129679A1 (ja) 2005-05-31 2006-12-07 Ono Pharmaceutical Co., Ltd. スピロピペリジン化合物およびその医薬用途
DK1942108T3 (da) 2005-10-28 2013-12-09 Ono Pharmaceutical Co Forbindelse indeholdende basisk gruppe samt anvendelse deraf
ES2407115T3 (es) 2005-11-18 2013-06-11 Ono Pharmaceutical Co., Ltd. Compuesto que contiene un grupo básico y uso del mismo
MX2008011414A (es) 2006-03-10 2008-09-22 Ono Pharmaceutical Co Derivado heterociclico nitrogenado y agente farmaceutico que comprende el derivado como ingrediente activo.
US8618122B2 (en) 2006-05-16 2013-12-31 Ono Pharmaceutical Co., Ltd. Compound having acidic group which may be protected, and use thereof
JP5245827B2 (ja) 2006-07-31 2013-07-24 小野薬品工業株式会社 スピロ結合した環状基を含有する化合物およびその用途
WO2010129351A1 (en) 2009-04-28 2010-11-11 Schepens Eye Research Institute Method to identify and treat age-related macular degeneration
WO2013024022A1 (en) 2011-08-12 2013-02-21 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and pharmaceutical compositions for treatment of pulmonary hypertension
US9187451B2 (en) 2011-11-18 2015-11-17 Heptares Therapeutics Limited Muscarinic M1 receptor agonists
SG10201908048QA (en) * 2014-01-08 2019-10-30 Immunovative Therapies Ltd Treatment of Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome
GB201513743D0 (en) 2015-08-03 2015-09-16 Heptares Therapeutics Ltd Muscarinic agonists
GB201519352D0 (en) 2015-11-02 2015-12-16 Heptares Therapeutics Ltd Pharmaceutical compounds
GB201617454D0 (en) 2016-10-14 2016-11-30 Heptares Therapeutics Limited Pharmaceutical compounds
GB201810239D0 (en) 2018-06-22 2018-08-08 Heptares Therapeutics Ltd Pharmaceutical compounds
GB201819960D0 (en) 2018-12-07 2019-01-23 Heptares Therapeutics Ltd Pharmaceutical compounds
GB202020191D0 (en) 2020-12-18 2021-02-03 Heptares Therapeutics Ltd Pharmaceutical compounds
US11629196B2 (en) 2020-04-27 2023-04-18 Incelldx, Inc. Method of treating SARS-CoV-2-associated hypercytokinemia by administering a human monoclonal antibody (PRO-140) that inhibits CCR5/CCL5 binding interactions

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5889006A (en) * 1995-02-23 1999-03-30 Schering Corporation Muscarinic antagonists
PT858343E (pt) * 1995-11-02 2004-07-30 Schering Corp Terapia por infusao continua de uma dose baixa de citoquina
US5908621A (en) * 1995-11-02 1999-06-01 Schering Corporation Polyethylene glycol modified interferon therapy
GB9609932D0 (en) * 1996-05-13 1996-07-17 Hoffmann La Roche Use of IL-12 and IFN alpha for the treatment of infectious diseases
WO1998025617A1 (en) * 1996-12-13 1998-06-18 Merck & Co., Inc. Substituted aryl piperazines as modulators of chemokine receptor activity
AR013669A1 (es) * 1997-10-07 2001-01-10 Smithkline Beecham Corp Compuestos y metodos

Also Published As

Publication number Publication date
ZA200108870B (en) 2003-03-26
EP1175224B1 (en) 2005-02-23
DE60018273D1 (de) 2005-03-31
ES2238277T3 (es) 2005-09-01
HUP0202734A2 (hu) 2002-12-28
CA2365900A1 (en) 2000-11-09
WO2000066141A3 (en) 2001-02-08
HK1039278A1 (en) 2002-04-19
WO2000066141A2 (en) 2000-11-09
AR023824A1 (es) 2002-09-04
CN1349408A (zh) 2002-05-15
MXPA01011116A (es) 2002-06-04
EP1175224A2 (en) 2002-01-30
MY127670A (en) 2006-12-29
DE60018273T2 (de) 2005-08-18
ATE289516T1 (de) 2005-03-15
NO328679B1 (no) 2010-04-26
JP2002543144A (ja) 2002-12-17
BR0010593A (pt) 2002-02-13
NO20015367L (no) 2002-01-03
HUP0202734A3 (en) 2003-11-28
PE20010283A1 (es) 2001-03-16
NO20015367D0 (no) 2001-11-02
AU776541B2 (en) 2004-09-16
NZ514519A (en) 2003-07-25
AU4681500A (en) 2000-11-17
TWI289454B (en) 2007-11-11
HK1039278B (zh) 2005-06-30

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