HK1039278B - PEG化的干擾素-α-CCR5拮抗劑組合HIV療法 - Google Patents

PEG化的干擾素-α-CCR5拮抗劑組合HIV療法

Info

Publication number: HK1039278B
Authority: HK; Hong Kong
Prior art keywords: interferon alfa; pegylated interferon; ccr5 antagonist; antagonist combination; hiv therapy
Prior art date: 1999-05-04

Application number

HK02100826.8A

Other languages

English (en)

Other versions

HK1039278A1 (en

Inventor

A Laughlin Mark

Original Assignee

Schering Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-05-04

Filing date

2002-02-02

Publication date

2005-06-30

2002-02-02 Application filed by Schering Corp filed Critical Schering Corp

2002-04-19 Publication of HK1039278A1 publication Critical patent/HK1039278A1/xx

2005-06-30 Publication of HK1039278B publication Critical patent/HK1039278B/zh

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
- A61K38/212—IFN-alpha
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Virology (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Oncology (AREA)
Molecular Biology (AREA)
Bioinformatics & Cheminformatics (AREA)
Communicable Diseases (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Epidemiology (AREA)
Immunology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
AIDS & HIV (AREA)
Tropical Medicine & Parasitology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

HK02100826.8A 1999-05-04 2002-02-02 PEG化的干擾素-α-CCR5拮抗劑組合HIV療法 HK1039278B (zh)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US30489799A	1999-05-04	1999-05-04
PCT/US2000/011634 WO2000066141A2 (en)	1999-05-04	2000-05-01	Pegylated interferon alfa-ccr5 antagonist combination hiv therapy

Publications (2)

Publication Number	Publication Date
HK1039278A1 HK1039278A1 (en)	2002-04-19
HK1039278B true HK1039278B (zh)	2005-06-30

Family

ID=23178462

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HK02100826.8A HK1039278B (zh)	1999-05-04	2002-02-02	PEG化的干擾素-α-CCR5拮抗劑組合HIV療法

Country Status (21)

Country	Link
EP (1)	EP1175224B1 (zh)
JP (1)	JP2002543144A (zh)
CN (1)	CN1349408A (zh)
AR (1)	AR023824A1 (zh)
AT (1)	ATE289516T1 (zh)
AU (1)	AU776541B2 (zh)
BR (1)	BR0010593A (zh)
CA (1)	CA2365900A1 (zh)
DE (1)	DE60018273T2 (zh)
ES (1)	ES2238277T3 (zh)
HK (1)	HK1039278B (zh)
HU (1)	HUP0202734A3 (zh)
MX (1)	MXPA01011116A (zh)
MY (1)	MY127670A (zh)
NO (1)	NO328679B1 (zh)
NZ (1)	NZ514519A (zh)
PE (1)	PE20010283A1 (zh)
PT (1)	PT1175224E (zh)
TW (1)	TWI289454B (zh)
WO (1)	WO2000066141A2 (zh)
ZA (1)	ZA200108870B (zh)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20050065319A1 (en) *	2000-12-19	2005-03-24	Baroudy Bahige M.	Combination method for treating viral infections
NZ542304A (en)	2003-03-14	2009-07-31	Ono Pharmaceutical Co	Nitrogen-containing heterocyclic derivatives and drugs containing the same as the active ingredient
JP4710606B2 (ja)	2003-04-18	2011-06-29	小野薬品工業株式会社	スピロピペリジン化合物およびその医薬用途
WO2004092136A1 (ja) *	2003-04-18	2004-10-28	Ono Pharmaceutical Co., Ltd.	含窒素複素環化合物およびその用途
ATE374838T1 (de)	2004-04-29	2007-10-15	Hoffmann La Roche	Nukleotidsequenzvariation im gen ns5a als marker
TWI400232B (zh)	2004-09-13	2013-07-01	Ono Pharmaceutical Co	含氮雜環衍生物及以該含氮雜環衍生物為有效成分之藥劑
AU2006216731A1 (en) *	2005-02-23	2006-08-31	Schering Corporation	Piperidinyl piperazine derivatives useful as inhibitors of chemokine receptors
WO2006129679A1 (ja)	2005-05-31	2006-12-07	Ono Pharmaceutical Co., Ltd.	スピロピペリジン化合物およびその医薬用途
DK1942108T3 (da)	2005-10-28	2013-12-09	Ono Pharmaceutical Co	Forbindelse indeholdende basisk gruppe samt anvendelse deraf
ES2407115T3 (es)	2005-11-18	2013-06-11	Ono Pharmaceutical Co., Ltd.	Compuesto que contiene un grupo básico y uso del mismo
MX2008011414A (es)	2006-03-10	2008-09-22	Ono Pharmaceutical Co	Derivado heterociclico nitrogenado y agente farmaceutico que comprende el derivado como ingrediente activo.
US8618122B2 (en)	2006-05-16	2013-12-31	Ono Pharmaceutical Co., Ltd.	Compound having acidic group which may be protected, and use thereof
JP5245827B2 (ja)	2006-07-31	2013-07-24	小野薬品工業株式会社	スピロ結合した環状基を含有する化合物およびその用途
WO2010129351A1 (en)	2009-04-28	2010-11-11	Schepens Eye Research Institute	Method to identify and treat age-related macular degeneration
WO2013024022A1 (en)	2011-08-12	2013-02-21	INSERM (Institut National de la Santé et de la Recherche Médicale)	Methods and pharmaceutical compositions for treatment of pulmonary hypertension
US9187451B2 (en)	2011-11-18	2015-11-17	Heptares Therapeutics Limited	Muscarinic M1 receptor agonists
SG10201908048QA (en) *	2014-01-08	2019-10-30	Immunovative Therapies Ltd	Treatment of Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome
GB201513743D0 (en)	2015-08-03	2015-09-16	Heptares Therapeutics Ltd	Muscarinic agonists
GB201519352D0 (en)	2015-11-02	2015-12-16	Heptares Therapeutics Ltd	Pharmaceutical compounds
GB201617454D0 (en)	2016-10-14	2016-11-30	Heptares Therapeutics Limited	Pharmaceutical compounds
GB201810239D0 (en)	2018-06-22	2018-08-08	Heptares Therapeutics Ltd	Pharmaceutical compounds
GB201819960D0 (en)	2018-12-07	2019-01-23	Heptares Therapeutics Ltd	Pharmaceutical compounds
GB202020191D0 (en)	2020-12-18	2021-02-03	Heptares Therapeutics Ltd	Pharmaceutical compounds
US11629196B2 (en)	2020-04-27	2023-04-18	Incelldx, Inc.	Method of treating SARS-CoV-2-associated hypercytokinemia by administering a human monoclonal antibody (PRO-140) that inhibits CCR5/CCL5 binding interactions

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5889006A (en) *	1995-02-23	1999-03-30	Schering Corporation	Muscarinic antagonists
PT858343E (pt) *	1995-11-02	2004-07-30	Schering Corp	Terapia por infusao continua de uma dose baixa de citoquina
US5908621A (en) *	1995-11-02	1999-06-01	Schering Corporation	Polyethylene glycol modified interferon therapy
GB9609932D0 (en) *	1996-05-13	1996-07-17	Hoffmann La Roche	Use of IL-12 and IFN alpha for the treatment of infectious diseases
WO1998025617A1 (en) *	1996-12-13	1998-06-18	Merck & Co., Inc.	Substituted aryl piperazines as modulators of chemokine receptor activity
AR013669A1 (es) *	1997-10-07	2001-01-10	Smithkline Beecham Corp	Compuestos y metodos

2000
- 2000-05-01 CA CA002365900A patent/CA2365900A1/en not_active Abandoned
- 2000-05-01 AU AU46815/00A patent/AU776541B2/en not_active Ceased
- 2000-05-01 AT AT00928604T patent/ATE289516T1/de not_active IP Right Cessation
- 2000-05-01 MX MXPA01011116A patent/MXPA01011116A/es active IP Right Grant
- 2000-05-01 HU HU0202734A patent/HUP0202734A3/hu unknown
- 2000-05-01 BR BR0010593-7A patent/BR0010593A/pt not_active Application Discontinuation
- 2000-05-01 ES ES00928604T patent/ES2238277T3/es not_active Expired - Lifetime
- 2000-05-01 PT PT00928604T patent/PT1175224E/pt unknown
- 2000-05-01 CN CN00807116A patent/CN1349408A/zh active Pending
- 2000-05-01 DE DE60018273T patent/DE60018273T2/de not_active Expired - Lifetime
- 2000-05-01 WO PCT/US2000/011634 patent/WO2000066141A2/en active IP Right Grant
- 2000-05-01 JP JP2000615025A patent/JP2002543144A/ja not_active Ceased
- 2000-05-01 EP EP00928604A patent/EP1175224B1/en not_active Expired - Lifetime
- 2000-05-01 NZ NZ514519A patent/NZ514519A/en not_active IP Right Cessation
- 2000-05-02 PE PE2000000408A patent/PE20010283A1/es not_active Application Discontinuation
- 2000-05-02 AR ARP000102097A patent/AR023824A1/es unknown
- 2000-05-02 MY MYPI20001893A patent/MY127670A/en unknown
- 2000-05-02 TW TW089108323A patent/TWI289454B/zh not_active IP Right Cessation
2001
- 2001-10-26 ZA ZA200108870A patent/ZA200108870B/xx unknown
- 2001-11-02 NO NO20015367A patent/NO328679B1/no not_active IP Right Cessation
2002
- 2002-02-02 HK HK02100826.8A patent/HK1039278B/zh not_active IP Right Cessation

Also Published As

Publication number	Publication date
ZA200108870B (en)	2003-03-26
EP1175224B1 (en)	2005-02-23
DE60018273D1 (de)	2005-03-31
ES2238277T3 (es)	2005-09-01
HUP0202734A2 (hu)	2002-12-28
CA2365900A1 (en)	2000-11-09
WO2000066141A3 (en)	2001-02-08
HK1039278A1 (en)	2002-04-19
WO2000066141A2 (en)	2000-11-09
AR023824A1 (es)	2002-09-04
CN1349408A (zh)	2002-05-15
MXPA01011116A (es)	2002-06-04
EP1175224A2 (en)	2002-01-30
MY127670A (en)	2006-12-29
DE60018273T2 (de)	2005-08-18
ATE289516T1 (de)	2005-03-15
NO328679B1 (no)	2010-04-26
JP2002543144A (ja)	2002-12-17
PT1175224E (pt)	2005-07-29
BR0010593A (pt)	2002-02-13
NO20015367L (no)	2002-01-03
HUP0202734A3 (en)	2003-11-28
PE20010283A1 (es)	2001-03-16
NO20015367D0 (no)	2001-11-02
AU776541B2 (en)	2004-09-16
NZ514519A (en)	2003-07-25
AU4681500A (en)	2000-11-17
TWI289454B (en)	2007-11-11

Publication	Publication Date	Title
HK1039278B (zh)	2005-06-30	PEG化的干擾素-α-CCR5拮抗劑組合HIV療法
HK1200316A1 (zh)	2015-08-07	治療微泡沫
EP1187827A4 (en)	2002-10-24	ANTIVIRAL ACTIVE SUBSTANCE
GB9911863D0 (en)	1999-07-21	Therapeutic agents
GB9905010D0 (en)	1999-04-28	Therapeutic agents
IL150030A0 (en)	2002-12-01	Therapeutic agents
GB9904786D0 (en)	1999-04-28	Therapeutic agents
GB9929685D0 (en)	2000-02-09	Therapeutic agents
GB9929687D0 (en)	2000-02-09	Therapeutic agents
GB9911881D0 (en)	1999-07-21	Therapeutic agents
GB9921351D0 (en)	1999-11-10	Therapeutic agents
GB9911802D0 (en)	1999-07-21	Therapeutic combination
GB9929569D0 (en)	2000-02-09	Therapeutic agents
GB9903476D0 (en)	1999-04-07	Therapeutic agents
GB9911803D0 (en)	1999-07-21	Therapeutic combination
GB9911804D0 (en)	1999-07-21	Therapeutic combination
GB9914744D0 (en)	1999-08-25	Therapeutic agents
AU2002222557A1 (en)	2002-06-11	Interferon therapeutic effect-potentiating agents
GB9903119D0 (en)	1999-04-07	Therapeutic agents
IL147078A0 (en)	2002-08-14	Therapeutic agents
GB9914745D0 (en)	1999-08-25	Therapeutic agents
SI1175224T1 (en)	2005-06-30	Pegylated interferon alfa-ccr5 antagonist combination hiv therapy
GB9902881D0 (en)	1999-03-31	Therapeutic agents
GB9914743D0 (en)	1999-08-25	Therapeutic agents
GB9915616D0 (en)	1999-09-01	Therapeutic agents

Legal Events

Date	Code	Title	Description
2011-12-16	PC	Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)	Effective date: 20110501